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UY36431A - Anticuerpos monoclonales específicos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por hmpv - Google Patents

Anticuerpos monoclonales específicos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por hmpv

Info

Publication number
UY36431A
UY36431A UY0001036431A UY36431A UY36431A UY 36431 A UY36431 A UY 36431A UY 0001036431 A UY0001036431 A UY 0001036431A UY 36431 A UY36431 A UY 36431A UY 36431 A UY36431 A UY 36431A
Authority
UY
Uruguay
Prior art keywords
hmpv
monoclonal antibodies
antigen
diagnosis
secreted
Prior art date
Application number
UY0001036431A
Other languages
English (en)
Inventor
Bueno Ramírez Susan Marcela
Kalergis Parra Alexis Mikes
Mora Alarcón Jorge Eugenio
Original Assignee
Pontificia Universidad Católica De Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pontificia Universidad Católica De Chile filed Critical Pontificia Universidad Católica De Chile
Publication of UY36431A publication Critical patent/UY36431A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Anticuerpos monoclonales murinos, correspondientes a anticuerpos monoclonales secretados por líneas celulares de hibridomas denominados 3G8/C11 y 7G4/A12, y que reaccionan contra el antígeno M de hMPV. Estos anticuerpos no compiten entre sí por el sitio de unión al antígeno, ni ejercen un impedimento para unirse simultáneamente a este. Dichos anticuerpos monoclonales pueden ser utilizados para ensayos de detección, diagnóstico y/o determinación de infección por hMPV.
UY0001036431A 2014-12-11 2015-12-11 Anticuerpos monoclonales específicos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por hmpv UY36431A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2014003373A CL2014003373A1 (es) 2014-12-11 2014-12-11 Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv.

Publications (1)

Publication Number Publication Date
UY36431A true UY36431A (es) 2016-01-29

Family

ID=53404103

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001036431A UY36431A (es) 2014-12-11 2015-12-11 Anticuerpos monoclonales específicos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por hmpv

Country Status (17)

Country Link
US (1) US9995747B2 (es)
EP (2) EP3231815A4 (es)
KR (1) KR102339334B1 (es)
CN (1) CN107207584B (es)
AR (1) AR102966A1 (es)
BR (1) BR112017012511B1 (es)
CA (2) CA3168348A1 (es)
CL (1) CL2014003373A1 (es)
CO (1) CO2017005781A2 (es)
DE (1) DE112015005539T5 (es)
GB (2) GB2547603B (es)
MX (1) MX2017007611A (es)
PE (1) PE20171734A1 (es)
RU (1) RU2698052C2 (es)
UY (1) UY36431A (es)
WO (1) WO2016092380A1 (es)
ZA (2) ZA201704530B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3848389A4 (en) * 2018-09-03 2022-04-13 Pontificia Universidad Católica De Chile SPECIFIC MONOCLONAL ANTIBODIES AGAINST HUMAN RESPIRATORY SYNCYTIAL VIRUS (HRSV) N-ANTIGEN FOR TREATMENT, DETECTION AND DIAGNOSIS OF INFECTION
JP7274904B2 (ja) * 2019-03-26 2023-05-17 田中貴金属工業株式会社 ヒトメタニューモウイルス検出用試薬
CN119143871B (zh) * 2024-11-20 2025-02-07 首都儿科研究所 用于人偏肺病毒检测的单克隆抗体、检测试剂及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715922B2 (en) * 2001-01-19 2014-05-06 ViroNovative Virus causing respiratory tract illness in susceptible mammals
CA2523319A1 (en) 2003-04-25 2004-11-11 Medimmune Vaccines, Inc. Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
EP1473037A1 (en) * 2003-05-02 2004-11-03 Vironovative B.V. Treatment of hPMV infections with Ribavirin
US20060216700A1 (en) * 2005-03-10 2006-09-28 Medimmune Vaccines, Inc. Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
CA2624291A1 (en) * 2005-10-03 2007-04-12 Seneca College Of Applied Arts & Technology Nucleic acid immunological composition for human metapneumovirus
US8492097B2 (en) * 2006-04-24 2013-07-23 Diagnostic Hybrids, Inc. Compositions and methods for human metapneumovirus monoclonal antibodies
WO2008043052A2 (en) * 2006-10-04 2008-04-10 The Scripps Research Institute Human antibodies neutralizing human metapneumovirus
WO2008148170A1 (en) * 2007-06-08 2008-12-11 The University Of Queensland Human metapneumovirus immunogenic peptides, compositions, and methods of use
CN102145167A (zh) * 2010-02-05 2011-08-10 重庆医科大学附属儿童医院 重组人类偏肺病毒疫苗
CL2011003002A1 (es) * 2011-11-25 2012-05-25 Univ Pontificia Catolica Chile Anticuerpo monoclonal o un fragmento del mismo que se une a la proteina m2-1 del virus respiratorio sincicial (vrs) humano; secuencias nucleotidicas; composicion farmaceutica; metodo de diagnostico de infeccion producida por vrs; kit; y uso de dicho anticuerpo para preparar un medicamento.

Also Published As

Publication number Publication date
US20170343546A1 (en) 2017-11-30
KR20170086668A (ko) 2017-07-26
GB2547603A (en) 2017-08-23
CL2014003373A1 (es) 2015-04-10
RU2698052C2 (ru) 2019-08-21
GB2568617A (en) 2019-05-22
CN107207584A (zh) 2017-09-26
CA2970482A1 (en) 2016-06-16
RU2017120228A3 (es) 2019-01-11
ZA201804550B (en) 2019-09-25
EP3495386A1 (en) 2019-06-12
MX2017007611A (es) 2017-09-18
US9995747B2 (en) 2018-06-12
GB2547603B (en) 2019-10-30
GB201709129D0 (en) 2017-07-26
DE112015005539T5 (de) 2017-08-31
BR112017012511A2 (pt) 2018-02-27
RU2017120228A (ru) 2019-01-11
CO2017005781A2 (es) 2017-08-31
AR102966A1 (es) 2017-04-05
EP3231815A1 (en) 2017-10-18
BR112017012511B1 (pt) 2023-12-12
EP3231815A4 (en) 2018-02-21
PE20171734A1 (es) 2017-12-04
KR102339334B1 (ko) 2021-12-14
GB201901874D0 (en) 2019-04-03
ZA201704530B (en) 2018-11-28
WO2016092380A1 (es) 2016-06-16
CN107207584B (zh) 2021-01-08
CA3168348A1 (en) 2016-06-16

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