[go: up one dir, main page]

CL2014003373A1 - Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv. - Google Patents

Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv.

Info

Publication number
CL2014003373A1
CL2014003373A1 CL2014003373A CL2014003373A CL2014003373A1 CL 2014003373 A1 CL2014003373 A1 CL 2014003373A1 CL 2014003373 A CL2014003373 A CL 2014003373A CL 2014003373 A CL2014003373 A CL 2014003373A CL 2014003373 A1 CL2014003373 A1 CL 2014003373A1
Authority
CL
Chile
Prior art keywords
hmpv
hybridomas
secreted
antigen
diagnosis
Prior art date
Application number
CL2014003373A
Other languages
English (en)
Inventor
Ramirez Susan Marcela Bueno
Parra Alexis Mikes Kalergis
Alarcon Jorge Eugenio Mora
Original Assignee
Univ Pontificia Catolica Chile
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pontificia Catolica Chile filed Critical Univ Pontificia Catolica Chile
Priority to CL2014003373A priority Critical patent/CL2014003373A1/es
Priority to EP18188183.0A priority patent/EP3495386A1/en
Priority to US15/535,170 priority patent/US9995747B2/en
Priority to CA3168348A priority patent/CA3168348A1/en
Priority to GB1709129.9A priority patent/GB2547603B/en
Priority to GB1901874.6A priority patent/GB2568617A/en
Priority to BR112017012511-0A priority patent/BR112017012511B1/pt
Priority to EP15866549.7A priority patent/EP3231815A4/en
Priority to PE2017000986A priority patent/PE20171734A1/es
Priority to MX2017007611A priority patent/MX383563B/es
Priority to PCT/IB2015/050790 priority patent/WO2016092380A1/es
Priority to CN201580073977.9A priority patent/CN107207584B/zh
Priority to CA2970482A priority patent/CA2970482A1/en
Priority to KR1020177019261A priority patent/KR102339334B1/ko
Priority to RU2017120228A priority patent/RU2698052C2/ru
Priority to DE112015005539.8T priority patent/DE112015005539T5/de
Publication of CL2014003373A1 publication Critical patent/CL2014003373A1/es
Priority to ARP150104031A priority patent/AR102966A1/es
Priority to UY0001036431A priority patent/UY36431A/es
Priority to CONC2017/0005781A priority patent/CO2017005781A2/es
Priority to ZA2017/04530A priority patent/ZA201704530B/en
Priority to ZA2018/04550A priority patent/ZA201804550B/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/115Paramyxoviridae, e.g. parainfluenza virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CL2014003373A 2014-12-11 2014-12-11 Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv. CL2014003373A1 (es)

Priority Applications (21)

Application Number Priority Date Filing Date Title
CL2014003373A CL2014003373A1 (es) 2014-12-11 2014-12-11 Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv.
MX2017007611A MX383563B (es) 2014-12-11 2015-02-02 Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnostico.
CA2970482A CA2970482A1 (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen m of the human metapneumovirus (hmpv), and use thereof in a diagnostic method
CA3168348A CA3168348A1 (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen m of the human metapneumovirus (hmpv), and use thereof in a diagnostic method
GB1709129.9A GB2547603B (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen M of the human metapneumovirus (HMPV) and use thereof in a diagnostic method
GB1901874.6A GB2568617A (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen M of the human metapneumovirus (HMPV), and use thereof in a diagnostic method
BR112017012511-0A BR112017012511B1 (pt) 2014-12-11 2015-02-02 Anticorpo monoclonal ou um fragmento do mesmo, método de diagnóstico in vitro e/ou ex vivo para a infecção por hmpv e kit de diagnóstico para a detecção de hmpv
EP15866549.7A EP3231815A4 (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen m of the human metapneumovirus (hmpv) and use thereof in a diagnostic method
PE2017000986A PE20171734A1 (es) 2014-12-11 2015-02-02 Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnostico
EP18188183.0A EP3495386A1 (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen m of the human metapneumovirus (hmpv) and use thereof in a diagnostic method
PCT/IB2015/050790 WO2016092380A1 (es) 2014-12-11 2015-02-02 Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y su uso en un metodo de diagnostico
CN201580073977.9A CN107207584B (zh) 2014-12-11 2015-02-02 人偏肺病毒(hmpv)的m抗原的特异性单克隆抗体及其在诊断方法中的用途
US15/535,170 US9995747B2 (en) 2014-12-11 2015-02-02 Specific monoclonal antibodies of the antigen M of the human metapneumovirus (HMPV) and use thereof in a diagnostic method
KR1020177019261A KR102339334B1 (ko) 2014-12-11 2015-02-02 인간 메타뉴모바이러스(hMPV)의 항원 M의 특이적 단클론 항체 및 진단 방법에 있어서의 그 용도
RU2017120228A RU2698052C2 (ru) 2014-12-11 2015-02-02 Особые моноклональные антитела антигена м метапневмовируса человека (hmpv) и способ их использования в методе диагностики
DE112015005539.8T DE112015005539T5 (de) 2014-12-11 2015-02-02 Spezifische monoklonale Antikörper des M-Antigens des Human-Metapneumvirus (HMPV) und deren Verwendung in einem Diagnoseverfahren
ARP150104031A AR102966A1 (es) 2014-12-11 2015-12-10 ANTICUERPOS MONOCLONALES ESPECÍFICOS PARA EL ANTÍGENO M DEL VIRUS METAPNEUMOVIRUS HUMANO (hMPV), PRODUCIDOS Y SECRETADOS POR HIBRIDOMAS CELULARES, ÚTILES PARA LA DETECCIÓN Y EL DIAGNÓSTICO DE LA INFECCIÓN CAUSADA POR hMPV
UY0001036431A UY36431A (es) 2014-12-11 2015-12-11 Anticuerpos monoclonales específicos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnóstico de la infección causada por hmpv
CONC2017/0005781A CO2017005781A2 (es) 2014-12-11 2017-06-12 Anticuerpos monoclonales especificos del antigeno m del virus metapneumovirus humano (hmpv) y metodo de diagnostico que involucra el mismo
ZA2017/04530A ZA201704530B (en) 2014-12-11 2017-07-04 Specific monoclonal antibodies of the antigen m of the human metapneumovirus (hmpv) and use thereof in a diagnostic method
ZA2018/04550A ZA201804550B (en) 2014-12-11 2018-07-09 Specific monoclonal antibodies of the antigen m of the human metapneumovirus (hmpv) and use thereof in a diagnostic method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CL2014003373A CL2014003373A1 (es) 2014-12-11 2014-12-11 Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv.

Publications (1)

Publication Number Publication Date
CL2014003373A1 true CL2014003373A1 (es) 2015-04-10

Family

ID=53404103

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014003373A CL2014003373A1 (es) 2014-12-11 2014-12-11 Anticuerpos monoclonales especificos para el antígeno m del virus metapneumovirus humano (hmpv), producidos y secretados por hibridomas celulares , útiles para la deteccion y el diagnostico de la infeccion causada por hmpv.

Country Status (17)

Country Link
US (1) US9995747B2 (es)
EP (2) EP3231815A4 (es)
KR (1) KR102339334B1 (es)
CN (1) CN107207584B (es)
AR (1) AR102966A1 (es)
BR (1) BR112017012511B1 (es)
CA (2) CA2970482A1 (es)
CL (1) CL2014003373A1 (es)
CO (1) CO2017005781A2 (es)
DE (1) DE112015005539T5 (es)
GB (2) GB2547603B (es)
MX (1) MX383563B (es)
PE (1) PE20171734A1 (es)
RU (1) RU2698052C2 (es)
UY (1) UY36431A (es)
WO (1) WO2016092380A1 (es)
ZA (2) ZA201704530B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112912394B (zh) * 2018-09-03 2024-04-16 智利天主教教皇大学 针对hrsv的n抗原的单抗,可用于治疗感染、其检测和诊断
JP7274904B2 (ja) * 2019-03-26 2023-05-17 田中貴金属工業株式会社 ヒトメタニューモウイルス検出用試薬
CN119143871B (zh) * 2024-11-20 2025-02-07 首都儿科研究所 用于人偏肺病毒检测的单克隆抗体、检测试剂及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715922B2 (en) * 2001-01-19 2014-05-06 ViroNovative Virus causing respiratory tract illness in susceptible mammals
EP2494987A1 (en) 2003-04-25 2012-09-05 MedImmune Vaccines, Inc. Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
EP1473037A1 (en) * 2003-05-02 2004-11-03 Vironovative B.V. Treatment of hPMV infections with Ribavirin
WO2006099360A2 (en) * 2005-03-10 2006-09-21 Medimmune Vaccines, Inc. Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
US20090123529A1 (en) * 2005-10-03 2009-05-14 Xiaomao Li Nucleic acid immunological composition for human metapneumovirus
US8492097B2 (en) * 2006-04-24 2013-07-23 Diagnostic Hybrids, Inc. Compositions and methods for human metapneumovirus monoclonal antibodies
CA2665447A1 (en) * 2006-10-04 2008-04-10 The Scripps Research Institute Human antibodies neutralizing human metapneumovirus
WO2008148170A1 (en) * 2007-06-08 2008-12-11 The University Of Queensland Human metapneumovirus immunogenic peptides, compositions, and methods of use
CN102145167A (zh) * 2010-02-05 2011-08-10 重庆医科大学附属儿童医院 重组人类偏肺病毒疫苗
CL2011003002A1 (es) * 2011-11-25 2012-05-25 Univ Pontificia Catolica Chile Anticuerpo monoclonal o un fragmento del mismo que se une a la proteina m2-1 del virus respiratorio sincicial (vrs) humano; secuencias nucleotidicas; composicion farmaceutica; metodo de diagnostico de infeccion producida por vrs; kit; y uso de dicho anticuerpo para preparar un medicamento.

Also Published As

Publication number Publication date
ZA201804550B (en) 2019-09-25
GB2547603B (en) 2019-10-30
EP3231815A1 (en) 2017-10-18
BR112017012511B1 (pt) 2023-12-12
EP3231815A4 (en) 2018-02-21
GB2547603A (en) 2017-08-23
DE112015005539T5 (de) 2017-08-31
AR102966A1 (es) 2017-04-05
ZA201704530B (en) 2018-11-28
KR20170086668A (ko) 2017-07-26
RU2698052C2 (ru) 2019-08-21
MX2017007611A (es) 2017-09-18
MX383563B (es) 2025-03-14
GB2568617A (en) 2019-05-22
CO2017005781A2 (es) 2017-08-31
BR112017012511A2 (pt) 2018-02-27
RU2017120228A (ru) 2019-01-11
GB201709129D0 (en) 2017-07-26
EP3495386A1 (en) 2019-06-12
CN107207584B (zh) 2021-01-08
CA2970482A1 (en) 2016-06-16
PE20171734A1 (es) 2017-12-04
UY36431A (es) 2016-01-29
CN107207584A (zh) 2017-09-26
GB201901874D0 (en) 2019-04-03
KR102339334B1 (ko) 2021-12-14
WO2016092380A1 (es) 2016-06-16
US9995747B2 (en) 2018-06-12
RU2017120228A3 (es) 2019-01-11
US20170343546A1 (en) 2017-11-30
CA3168348A1 (en) 2016-06-16

Similar Documents

Publication Publication Date Title
CY1122804T1 (el) Μονοκλωνικα αντισωματα εναντι ανθρωπινου αντιγονου ωριμανσης β κυτταρων (βcμα)
PL3505535T3 (pl) Przeciwciało monoklonalne anty-pd1, jego kompozycja farmaceutyczna i jego zastosowanie
HUE053719T2 (hu) CTLA4 elleni monoklonális ellenanyag vagy annak antigénkötõ fragmentuma, gyógyásztati készítmény és alkalmazás
JOP20170004B1 (ar) الأجسام المضادة لببتيد بيتا النشوي مضاد N3pGlu واستخداماته
HUE053452T2 (hu) Anti-PD-1 és anti-LAG3 antitestek rák kezelésére
CO2017004516A2 (es) Anticuerpos anti-ox40 humanizados
CL2015002152A1 (es) Anticuerpos monoclonales específicos para el antígeno p del virus respiratorio sincicial humano (vrsh), producidos y secretados por hibridomas celulares, útiles para la detección y el diagnostico de la infección causada por vrsh
EA201500995A1 (ru) Биспецифические антитела, специфические в отношении fap и dr5, антитела, специфические в отношении dr5, и способы их применения
LT3556775T (lt) Anti-lag-3 antikūnai, skirti hematologinių piktybinių susirgimų gydymui
HUE055407T2 (hu) PD1-re és TIM3-ra specifikus bispecifikus antitestek
EA201691991A1 (ru) Мультиспецифические антитела
DK3309174T3 (da) ANTI-PD-L1-antistoffer og diagnostiske anvendelser deraf
HUE049081T2 (hu) GP120 elleni neutralizáló antitestek és alkalmazásuk
HUE053641T2 (hu) Anti-LAG3 antitestek és antigénkötõ fragmentumok
HUE049083T2 (hu) Humanizált, humán CD19 elleni antitestek és alkalmazási eljárások
EP3589648A4 (en) MONOCLONAL ANTI-RSV ANTIBODY FORMULATION
EA201691473A1 (ru) Биспецифические анти-il-13/il-17 антитела и их применение
CR20160270A (es) ANTICUERPOS ANTI-TAU (pS422) HUMANIZADOS Y MÉTODOS DE UTILIZACIÓN
CO2017007121A2 (es) Compuestos bicíclicos fusionados para el tratamiento de enfermedades
JO3791B1 (ar) تركيبات و طرق الأجسام المضادة المستهدفة لـ bmp6
BR112017015880A2 (pt) anticorpos, usos e métodos
HUE048855T2 (hu) RSV-re specifikus ellenanyagok és azok funkcionális részei
HUE053736T2 (hu) ANTI-CD28, humanizált antitestek embereknek történõ beadásra kiszerelve
ZA201804705B (en) Monoclonal antibodies specific for the piii antigen of human adenovirus (adv), produced and secreted by cell hybridomas, useful for detection and diagnosis of adv infection
HUE052528T2 (hu) Anti szklerosztin antitest, antigénkötõ fragmens és annak orvosi használata