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UA39918C2 - ПОХІДНІ ЦИКЛОПЕНТАН- АБО ЦИКЛОПЕНТЕН-<font face="Symbol">b</font>-АМІНОКИСЛОТ ТА ЇХ СОЛІ, КОМПОЗИЦІЯ, АКТИВНА ЩОДО ШТАМІВ S. AUREUS, CANDIDA I TRICHOPHYTON - Google Patents

ПОХІДНІ ЦИКЛОПЕНТАН- АБО ЦИКЛОПЕНТЕН-<font face="Symbol">b</font>-АМІНОКИСЛОТ ТА ЇХ СОЛІ, КОМПОЗИЦІЯ, АКТИВНА ЩОДО ШТАМІВ S. AUREUS, CANDIDA I TRICHOPHYTON

Info

Publication number
UA39918C2
UA39918C2 UA93002975A UA93002975A UA39918C2 UA 39918 C2 UA39918 C2 UA 39918C2 UA 93002975 A UA93002975 A UA 93002975A UA 93002975 A UA93002975 A UA 93002975A UA 39918 C2 UA39918 C2 UA 39918C2
Authority
UA
Ukraine
Prior art keywords
alcohol
font
purified
ethyl alcohol
amount
Prior art date
Application number
UA93002975A
Other languages
English (en)
Inventor
Йоахім Міттендорф
Франц Куніш
Міхаєль Матцке
Ханс-Крістіан Мілітцер
Ханс-Кристиан Милитцер
Райнер Ендерманн
Райнер Эндерманн
Карл Георг Метцгер
Клаус-Дітер БРЕММ
Клаус-Дитер БРЕММ
Манфред Племпель
Original Assignee
Байєр Аг
Байер Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4217776A external-priority patent/DE4217776A1/de
Priority claimed from DE4302155A external-priority patent/DE4302155A1/de
Application filed by Байєр Аг, Байер Аг filed Critical Байєр Аг
Publication of UA39918C2 publication Critical patent/UA39918C2/uk

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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/35—Unsaturated compounds having unsaturation outside the rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/18—Hydroxylamino compounds or their ethers or esters having nitrogen atoms of hydroxylamino groups further bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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    • C07C251/42—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
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    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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    • C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/36—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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    • C07C69/753—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring of polycyclic acids
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    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
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    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Спосіб приготування розчину водно-етанольного типового. Винахід відноситься до харчової промисловості, зокрема до лікеро-горілчаної галузі. Спосіб передбачає очистку спирту етилового та змішування його з водою дистильованою і реактивами. Спирт етиловий очищають до вмісту домішок, в перерахунку на безводний спирт: альдегідів 0,1-1,0 мг/дм3, сивушного масла 0,1-2,0 мг/дм3, метилового спирту 0,001-0,01 об.%. Спирт етиловий очищають від сивушного масла хімічним способом при дії порошку алюмінію і їдкого калію кількістю по 8-10 г/дм3 кожного протягом 50-80 хвилин при температурі 70-90 С з подальшим фракціонуванням спирту. Далі спирт етиловий очищають від альдегідів та метилового спирту хімічним способом при дії оцтовокислого свинцю кількістю 2,5-3 г/дм3 і їдкого калію кількістю 4-5 г/дм3 протягом 10-12 годин при температурі 15-25 С з подальшим фракціонуванням спирту. Технічним результатом винаходу є зниження до оптимальної допустимих концентрацій шкідливих домішок в вихідному спирті.
UA93002975A 1992-05-29 1993-06-17 ПОХІДНІ ЦИКЛОПЕНТАН- АБО ЦИКЛОПЕНТЕН-<font face="Symbol">b</font>-АМІНОКИСЛОТ ТА ЇХ СОЛІ, КОМПОЗИЦІЯ, АКТИВНА ЩОДО ШТАМІВ S. AUREUS, CANDIDA I TRICHOPHYTON UA39918C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4217776A DE4217776A1 (de) 1992-05-29 1992-05-29 Cyclopentan- und penten-µ-Aminosäuren
DE4302155A DE4302155A1 (de) 1993-01-27 1993-01-27 Verwendung von Cyclopentan- und -penten-beta-Aminosäuren

Publications (1)

Publication Number Publication Date
UA39918C2 true UA39918C2 (uk) 2001-07-16

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ID=25915249

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Application Number Title Priority Date Filing Date
UA93002975A UA39918C2 (uk) 1992-05-29 1993-06-17 ПОХІДНІ ЦИКЛОПЕНТАН- АБО ЦИКЛОПЕНТЕН-<font face="Symbol">b</font>-АМІНОКИСЛОТ ТА ЇХ СОЛІ, КОМПОЗИЦІЯ, АКТИВНА ЩОДО ШТАМІВ S. AUREUS, CANDIDA I TRICHOPHYTON

Country Status (27)

Country Link
US (1) US5739160A (uk)
EP (1) EP0571870B1 (uk)
JP (1) JP3565878B2 (uk)
KR (1) KR100300692B1 (uk)
CN (1) CN1065237C (uk)
AT (1) ATE169900T1 (uk)
AU (1) AU673824B2 (uk)
CA (1) CA2097044C (uk)
CZ (1) CZ286591B6 (uk)
DE (1) DE59308884D1 (uk)
DK (1) DK0571870T3 (uk)
ES (1) ES2121892T3 (uk)
FI (2) FI932427L (uk)
HK (1) HK1005132A1 (uk)
HR (1) HRP930938B1 (uk)
HU (1) HUT65188A (uk)
IL (1) IL105797A (uk)
MX (1) MX9303123A (uk)
MY (1) MY128260A (uk)
NO (1) NO304784B1 (uk)
NZ (1) NZ247715A (uk)
PH (1) PH31079A (uk)
RU (1) RU2126379C1 (uk)
SI (1) SI9300286B (uk)
SK (1) SK282660B6 (uk)
TW (1) TW264461B (uk)
UA (1) UA39918C2 (uk)

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WO1995007022A1 (en) * 1993-09-07 1995-03-16 Zeneca Limited Fungicides
DE4400749A1 (de) * 1994-01-13 1995-07-20 Bayer Ag Neues hochenantioselektives Verfahren zur Herstellung von enantiomerenreinen Cyclopentan- und -penten-beta-Aminosäuren
GB2291873A (en) * 1994-08-03 1996-02-07 Zeneca Ltd Fungicidal cyclopenta-oxazines and thiazines
DE19526274A1 (de) * 1995-07-19 1997-01-23 Bayer Ag Verbesserung der Verträglichkeit von pharmazeutisch wirksamen beta-Aminosäuren
DE19526275A1 (de) * 1995-07-19 1997-01-23 Bayer Ag Cyclopentan-beta-aminosäure-tripeptide
DE19617772A1 (de) * 1996-05-03 1997-11-13 Bayer Ag Neues effizientes und hochenantioselektives Verfahren zur Herstellung von enantiomerenreinen Cyclopentan-beta-aminosäuren
WO1997047194A1 (en) 1996-06-14 1997-12-18 Biocryst Pharmaceuticals, Inc. Substituted cyclopentane compounds useful as neuraminidase inhibitors
US6060585A (en) 1997-03-04 2000-05-09 Wisconsin Alumni Research Foundation β-polypeptide foldamers of well-defined secondary structure
AU2200199A (en) * 1997-12-17 1999-07-19 Biocryst Pharmaceuticals, Inc. Substituted cyclopentane and cyclopentene compounds useful as neuraminidase inhibitors
WO2000028328A1 (en) 1998-11-05 2000-05-18 Biocryst Pharmaceuticals, Inc. New cyclopentane and cyclopentene compounds and use for detecting influenza virus
WO2003008439A1 (en) * 2001-07-18 2003-01-30 Wisconsin Alumni Research Foundation ANTIMICROBIAL COMPOSITIONS CONTAINING β-AMINO ACID OLIGOMERS
US7084178B2 (en) * 2003-11-26 2006-08-01 Bristol-Myers Squibb Company Antiamyloid phenylsulfonamides: N-cycloalkylcarboxamides derivatives
FR2874014B1 (fr) * 2004-08-03 2010-05-14 Univ Paris Descartes Analogues d'aminoglycosides, leur utilisation et leur synthese
CN102459169B (zh) 2009-05-15 2014-12-31 莱德克斯制药有限公司 氧化还原药物衍生物
CN103154075B (zh) * 2010-09-30 2016-03-16 日本瑞翁株式会社 环戊烯开环聚合物及其制造方法
WO2017051922A1 (ja) 2015-09-25 2017-03-30 三菱レイヨン株式会社 （メタ）アクリル系共重合体、重合体溶液、重合体含有組成物、防汚塗料組成物及び（メタ）アクリル系共重合体の製造方法

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AU3829393A (en) 1993-12-02
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AU673824B2 (en) 1996-11-28
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