SU667141A3 - Способ получени диметил-2-оксо-3феноксипропилфосфоната - Google Patents
Способ получени диметил-2-оксо-3феноксипропилфосфонатаInfo
- Publication number
- SU667141A3 SU667141A3 SU752106791A SU2106791A SU667141A3 SU 667141 A3 SU667141 A3 SU 667141A3 SU 752106791 A SU752106791 A SU 752106791A SU 2106791 A SU2106791 A SU 2106791A SU 667141 A3 SU667141 A3 SU 667141A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- oxo
- phenoxypropyl
- phosphate
- producing dimethyl
- dimethyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims 2
- VYZKJJNBLLEWQJ-UHFFFAOYSA-N (3-methyl-2-oxo-3-phenoxybutyl) dihydrogen phosphate Chemical compound OP(=O)(O)OCC(=O)C(C)(C)OC1=CC=CC=C1 VYZKJJNBLLEWQJ-UHFFFAOYSA-N 0.000 title 1
- VONWDASPFIQPDY-UHFFFAOYSA-N dimethyl methylphosphonate Chemical compound COP(C)(=O)OC VONWDASPFIQPDY-UHFFFAOYSA-N 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- BZCKRPHEZOHHBK-UHFFFAOYSA-N methyl 2-phenoxyacetate Chemical compound COC(=O)COC1=CC=CC=C1 BZCKRPHEZOHHBK-UHFFFAOYSA-N 0.000 claims 1
- 125000001979 organolithium group Chemical group 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5407—Acyclic saturated phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Claims (1)
- 3 66714 . -...--..,s, ..... -C-CHj-P-) и 6,8-7,5 (м 5Н, apcwaQ . тические протоны). Формула изобретени Способ получени диметил-2-оксо-З-фенрксипропилфосфбната формулы Н п««Н СПИНОР ОСН СвЙ50СН2СОСПг 1« йз12 i 14 о т ли ч а ю щ и и. с тем, что метил-2-феноксиацетат подвергают взаимодействию с диметилметилфосфонатом в присутствии .литийорганического со (единени с последующим выделением целевого продукта. Источники информации, прин тые во внимание при экспертизе 1. Вьтоженна за вка ФРГ 2150361, кл. G 07 С 61/32, 13.04.72.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30481372A | 1972-11-08 | 1972-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU667141A3 true SU667141A3 (ru) | 1979-06-05 |
Family
ID=23178133
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU7301971722A SU584766A3 (ru) | 1972-11-08 | 1973-11-11 | Способ получени производных -тетранорпростагландинов или их эпимеров по с -или их солей |
| SU752106791A SU667141A3 (ru) | 1972-11-08 | 1975-02-18 | Способ получени диметил-2-оксо-3феноксипропилфосфоната |
| SU752106125A SU893130A3 (ru) | 1972-11-08 | 1975-02-19 | Способ получени простагландинов или их эпимеров с15 или с9 и с15 эпимеров |
| SU782629453A SU745362A3 (ru) | 1972-11-08 | 1978-07-27 | Способ получени производных простагландинов или их с и с эпимеров |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU7301971722A SU584766A3 (ru) | 1972-11-08 | 1973-11-11 | Способ получени производных -тетранорпростагландинов или их эпимеров по с -или их солей |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU752106125A SU893130A3 (ru) | 1972-11-08 | 1975-02-19 | Способ получени простагландинов или их эпимеров с15 или с9 и с15 эпимеров |
| SU782629453A SU745362A3 (ru) | 1972-11-08 | 1978-07-27 | Способ получени производных простагландинов или их с и с эпимеров |
Country Status (29)
| Country | Link |
|---|---|
| JP (3) | JPS5416491B2 (ru) |
| AR (3) | AR200585A1 (ru) |
| AT (3) | AT367034B (ru) |
| AU (1) | AU470375B2 (ru) |
| BE (1) | BE806995A (ru) |
| CA (3) | CA1085831A (ru) |
| CH (1) | CH597176A5 (ru) |
| CS (3) | CS182793B2 (ru) |
| DD (4) | DD118856A5 (ru) |
| DE (1) | DE2355540C2 (ru) |
| DK (1) | DK144247C (ru) |
| ES (3) | ES420325A1 (ru) |
| FI (1) | FI60389C (ru) |
| FR (3) | FR2205335B1 (ru) |
| GB (3) | GB1456512A (ru) |
| HK (3) | HK28079A (ru) |
| HU (3) | HU172703B (ru) |
| IE (1) | IE39537B1 (ru) |
| IL (1) | IL43589A (ru) |
| IN (1) | IN139384B (ru) |
| KE (3) | KE2932A (ru) |
| MY (3) | MY7900246A (ru) |
| NL (1) | NL164273C (ru) |
| NO (3) | NO147836C (ru) |
| PH (3) | PH13272A (ru) |
| SE (4) | SE448992B (ru) |
| SU (4) | SU584766A3 (ru) |
| YU (3) | YU39715B (ru) |
| ZA (1) | ZA738554B (ru) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929862A (en) * | 1974-01-08 | 1975-12-30 | Upjohn Co | Substituted tolylesters of PGF{HD 2{B {60 |
| GB1506817A (en) * | 1975-03-31 | 1978-04-12 | Upjohn Co | Prostaglandins |
| US3986764A (en) * | 1975-03-31 | 1976-10-19 | Gte Automatic Electric Laboratories Incorporated | Panel for supporting a pair of elongated mating connectors and selectively locking them together |
| ES449162A1 (es) * | 1975-06-23 | 1977-12-16 | Syntex Inc | Un procedimiento para la preparacion de un compuesto racemi-co u 8r-antimerico. |
| GB1516414A (en) * | 1975-08-22 | 1978-07-05 | Ici Ltd | Prostane derivatives |
| SE7809008L (sv) * | 1977-12-12 | 1979-06-13 | Upjohn Co | Anvendning av amider av prostaglandintyp for att styra eller reglera reproduktionscykeln hos individer tillhorande deggdjursarter |
| DK523378A (da) * | 1978-01-16 | 1979-07-17 | Pfizer | Fremgangsmaade til fremstilling af n-(tetrazol-5-yl) prostaglandin-carboxamider eller salte deraf |
| KR20010023838A (ko) * | 1997-09-09 | 2001-03-26 | 데이비드 엠 모이어 | Ｆｐ 작동약으로 유용한 방향족 ｃ16-ｃ20-치환된테트라히드로 프로스타글란딘 |
| IL145122A0 (en) | 1999-03-05 | 2002-06-30 | Procter & Gamble | C16 unsaturated fp-selective prostaglandin analogs |
| US6894175B1 (en) | 1999-08-04 | 2005-05-17 | The Procter & Gamble Company | 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use |
| US20020037914A1 (en) | 2000-03-31 | 2002-03-28 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| JP2002329615A (ja) * | 2001-05-02 | 2002-11-15 | Ohira Denshi Kk | トロイダルコイル |
| US6476064B1 (en) * | 2001-06-13 | 2002-11-05 | Allergan, Inc. | Cyclopentane heptan(ene) acyl sulfonamide, 2-alkyl or 2-arylalkyl, or 2-heteroarylalkenyl derivatives as therapeutic agents |
| EP1812017A2 (en) | 2004-10-21 | 2007-08-01 | Duke University | Ophthamological drugs |
| US8623918B2 (en) | 2008-10-29 | 2014-01-07 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
| US8722739B2 (en) | 2008-10-29 | 2014-05-13 | Novaer Holdings, Inc. | Amino acid salts of prostaglandins |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1324737A (en) * | 1970-11-02 | 1973-07-25 | Upjohn Co | Prostaglandins and the preparation thereof |
| IE37602B1 (en) * | 1971-05-11 | 1977-08-31 | Ici Ltd | Cyclopentane derivatives |
-
1972
- 1972-11-07 DD DD182498*A patent/DD118856A5/xx unknown
-
1973
- 1973-10-29 SE SE7314686A patent/SE448992B/xx unknown
- 1973-11-07 GB GB5175873A patent/GB1456512A/en not_active Expired
- 1973-11-07 PH PH15191A patent/PH13272A/en unknown
- 1973-11-07 DE DE2355540A patent/DE2355540C2/de not_active Expired
- 1973-11-07 FI FI3443/73A patent/FI60389C/fi active
- 1973-11-07 AU AU62247/73A patent/AU470375B2/en not_active Expired
- 1973-11-07 DK DK601073A patent/DK144247C/da not_active IP Right Cessation
- 1973-11-07 GB GB2395076A patent/GB1456513A/en not_active Expired
- 1973-11-07 GB GB2285876A patent/GB1456514A/en not_active Expired
- 1973-11-07 DD DD182497*A patent/DD117233A5/xx unknown
- 1973-11-07 YU YU2880/73A patent/YU39715B/xx unknown
- 1973-11-07 JP JP12527273A patent/JPS5416491B2/ja not_active Expired
- 1973-11-07 DD DD174504A patent/DD109212A5/xx unknown
- 1973-11-07 IE IE2002/73A patent/IE39537B1/xx unknown
- 1973-11-07 IN IN2448/CAL/73A patent/IN139384B/en unknown
- 1973-11-07 DD DD182499*A patent/DD119411A5/xx unknown
- 1973-11-07 ES ES420325A patent/ES420325A1/es not_active Expired
- 1973-11-07 CA CA185,274A patent/CA1085831A/en not_active Expired
- 1973-11-07 ZA ZA738554A patent/ZA738554B/xx unknown
- 1973-11-07 NO NO4288/73A patent/NO147836C/no unknown
- 1973-11-07 CH CH1563973A patent/CH597176A5/xx not_active IP Right Cessation
- 1973-11-07 AT AT0936973A patent/AT367034B/de not_active IP Right Cessation
- 1973-11-07 IL IL43589A patent/IL43589A/en unknown
- 1973-11-07 NL NL7315263.A patent/NL164273C/xx not_active IP Right Cessation
- 1973-11-07 FR FR7339544A patent/FR2205335B1/fr not_active Expired
- 1973-11-07 BE BE1005485A patent/BE806995A/xx not_active IP Right Cessation
- 1973-11-07 AR AR250885A patent/AR200585A1/es active
- 1973-11-08 HU HU72PI00000399A patent/HU172703B/hu unknown
- 1973-11-08 HU HU73PI451A patent/HU173507B/hu unknown
- 1973-11-08 CS CS7500006065A patent/CS182793B2/cs unknown
- 1973-11-08 HU HU73PI00000452A patent/HU171819B/hu unknown
- 1973-11-08 CS CS7500006066A patent/CS182794B2/cs unknown
- 1973-11-08 CS CS7300007669A patent/CS182791B2/cs unknown
- 1973-11-11 SU SU7301971722A patent/SU584766A3/ru active
-
1974
- 1974-06-06 AR AR254090A patent/AR202931A1/es active
- 1974-06-06 AR AR254091A patent/AR199966A1/es active
- 1974-09-26 NO NO743493A patent/NO148998C/no unknown
- 1974-12-18 ES ES433046A patent/ES433046A1/es not_active Expired
- 1974-12-18 ES ES433047A patent/ES433047A1/es not_active Expired
-
1975
- 1975-02-18 NO NO750535A patent/NO149139C/no unknown
- 1975-02-18 SU SU752106791A patent/SU667141A3/ru active
- 1975-02-19 SU SU752106125A patent/SU893130A3/ru active
- 1975-07-24 PH PH17410A patent/PH13110A/en unknown
- 1975-07-24 PH PH17409A patent/PH13325A/en unknown
- 1975-08-22 FR FR7526059A patent/FR2279729A1/fr active Granted
- 1975-08-22 FR FR7526060A patent/FR2283146A1/fr active Granted
-
1976
- 1976-07-23 AT AT544676A patent/AT353285B/de active
- 1976-07-23 AT AT544576A patent/AT360672B/de not_active IP Right Cessation
- 1976-10-15 JP JP51123738A patent/JPS5257147A/ja active Pending
- 1976-10-15 JP JP51123737A patent/JPS5253841A/ja active Pending
-
1977
- 1977-01-24 SE SE7700718A patent/SE431756B/xx not_active IP Right Cessation
- 1977-01-24 SE SE7700716A patent/SE445111B/xx not_active IP Right Cessation
- 1977-01-24 SE SE7700717A patent/SE436278B/xx not_active IP Right Cessation
- 1977-07-11 CA CA341,898A patent/CA1088931A/en not_active Expired
- 1977-07-11 CA CA341,897A patent/CA1088930A/en not_active Expired
-
1978
- 1978-07-27 SU SU782629453A patent/SU745362A3/ru active
-
1979
- 1979-03-15 KE KE2932A patent/KE2932A/xx unknown
- 1979-03-15 KE KE2931A patent/KE2931A/xx unknown
- 1979-03-15 KE KE2930A patent/KE2930A/xx unknown
- 1979-05-03 HK HK280/79A patent/HK28079A/xx unknown
- 1979-05-03 HK HK279/79A patent/HK27979A/xx unknown
- 1979-05-03 HK HK281/79A patent/HK28179A/xx unknown
- 1979-12-30 MY MY246/79A patent/MY7900246A/xx unknown
- 1979-12-30 MY MY245/79A patent/MY7900245A/xx unknown
- 1979-12-30 MY MY243/79A patent/MY7900243A/xx unknown
-
1980
- 1980-10-23 YU YU2706/80A patent/YU37316B/xx unknown
- 1980-10-23 YU YU2707/80A patent/YU36975B/xx unknown
Also Published As
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