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SK286384B6 - Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie - Google Patents

Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie Download PDF

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Publication number
SK286384B6
SK286384B6 SK848-2002A SK8482002A SK286384B6 SK 286384 B6 SK286384 B6 SK 286384B6 SK 8482002 A SK8482002 A SK 8482002A SK 286384 B6 SK286384 B6 SK 286384B6
Authority
SK
Slovakia
Prior art keywords
polypeptide
seq
antibody
amino acids
amino acid
Prior art date
Application number
SK848-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK8482002A3 (en
Inventor
Richard Harkins
Deborah Parkes
Gordon Parry
Douglas W. Schneider
Renate Steinbrecher
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of SK8482002A3 publication Critical patent/SK8482002A3/sk
Publication of SK286384B6 publication Critical patent/SK286384B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
SK848-2002A 1999-12-16 2000-12-15 Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie SK286384B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17237099P 1999-12-16 1999-12-16
US09/732,357 US6682902B2 (en) 1999-12-16 2000-12-07 DNA encoding a novel RG1 polypeptide
PCT/US2000/033901 WO2001044291A2 (en) 1999-12-16 2000-12-15 Polynucleotid encoding the rg1 polypeptide

Publications (2)

Publication Number Publication Date
SK8482002A3 SK8482002A3 (en) 2003-02-04
SK286384B6 true SK286384B6 (sk) 2008-08-05

Family

ID=26868022

Family Applications (2)

Application Number Title Priority Date Filing Date
SK848-2002A SK286384B6 (sk) 1999-12-16 2000-12-15 Izolované protilátky alebo fragmenty protilátok špecificky viažucich polypeptidy RG1, ich imunokonjugát a ich použitie
SK5055-2008A SK288147B6 (sk) 1999-12-16 2000-12-15 Isolated antibody or antibody fragment, which specifically bind to RG1 polypeptide, and immunoconjugate

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK5055-2008A SK288147B6 (sk) 1999-12-16 2000-12-15 Isolated antibody or antibody fragment, which specifically bind to RG1 polypeptide, and immunoconjugate

Country Status (32)

Country Link
US (5) US6682902B2 (bg)
EP (2) EP1237915B1 (bg)
JP (1) JP4979867B2 (bg)
KR (1) KR100752434B1 (bg)
CN (1) CN1297566C (bg)
AT (1) ATE440862T1 (bg)
AU (1) AU784674B2 (bg)
BG (1) BG65898B1 (bg)
BR (1) BR0017022A (bg)
CA (1) CA2394574A1 (bg)
CZ (1) CZ299232B6 (bg)
DE (1) DE60042836D1 (bg)
DK (1) DK1237915T3 (bg)
EE (1) EE05293B1 (bg)
ES (1) ES2331106T3 (bg)
HR (1) HRP20020549B1 (bg)
HU (1) HU229001B1 (bg)
IL (2) IL150115A0 (bg)
LT (1) LT5046B (bg)
ME (1) MEP37808A (bg)
MX (1) MXPA02005914A (bg)
NO (1) NO330924B1 (bg)
NZ (1) NZ519598A (bg)
PL (1) PL207634B1 (bg)
PT (1) PT1237915E (bg)
RO (1) RO122543B1 (bg)
RS (1) RS50831B (bg)
RU (1) RU2283130C2 (bg)
SI (2) SI21140A (bg)
SK (2) SK286384B6 (bg)
WO (1) WO2001044291A2 (bg)
ZA (1) ZA200205638B (bg)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

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US20020161199A1 (en) * 1998-04-08 2002-10-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
NZ528700A (en) * 1998-04-08 2005-02-25 Genentech Inc Novel PRO866 polypeptides and nucleic acids with homology to mindin and spondin proteins
US6960433B1 (en) 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US20070031901A1 (en) * 1999-03-08 2007-02-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
WO2005010048A2 (en) * 2003-07-22 2005-02-03 Schering Aktiengesellschaft Rg1 antibodies and uses thereof
US7294704B2 (en) 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
TWI494319B (zh) * 2007-02-21 2015-08-01 Oncotherapy Science Inc 表現腫瘤相關抗原之癌症的胜肽疫苗
CA2707443A1 (en) * 2007-11-30 2009-06-11 Bristol-Myers Squibb Company Conjugates of anti-rg-1 antibodies
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
CN102346184B (zh) * 2010-08-03 2014-03-26 中国人民解放军军事医学科学院生物工程研究所 Spon2的新用途

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5246692A (en) * 1986-09-05 1993-09-21 The United States Of America As Represented By The Secretary Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US4831175A (en) * 1986-09-05 1989-05-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5399493A (en) 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
US5437994A (en) 1989-06-15 1995-08-01 Regents Of The University Of Michigan Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
US5225212A (en) 1989-10-20 1993-07-06 Liposome Technology, Inc. Microreservoir liposome composition and method
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
DE69127627T2 (de) 1990-08-29 1998-02-19 Genpharm Int Produktion und Nützung nicht-menschliche transgentiere zur Produktion heterologe Antikörper
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
CA2135499A1 (en) 1992-05-14 1993-11-25 James D. Thompson Method and reagent for inhibiting cancer development
US5871969A (en) 1996-02-12 1999-02-16 Human Genome Sciences, Inc. Nucleic acids encoding human neuronal attachment factor-1
US6177244B1 (en) * 1996-05-10 2001-01-23 Beth Israel Deaconess Medical Center Inc. NPG-1 gene that is differentially expressed in prostate tumors
US5804382A (en) 1996-05-10 1998-09-08 Beth Israel Deaconess Medical Center, Inc. Methods for identifying differentially expressed genes and differences between genomic nucleic acid sequences
US6287777B1 (en) * 1996-05-10 2001-09-11 Beth Israel Deaconess Medical Center NPG-1 gene that is differentially expressed in prostate tumors
JP3494529B2 (ja) * 1996-06-06 2004-02-09 Ykk株式会社 一体成形面ファスナー
WO1998008381A1 (en) * 1996-08-26 1998-03-05 University Of Washington Therapeutic and diagnostic applications of perlecan domain i splice variants
WO1998045442A2 (en) 1997-04-10 1998-10-15 Zymogenetics, Inc. Secreted f-spondin homologs
WO1998050555A2 (en) * 1997-05-06 1998-11-12 Human Genome Sciences, Inc. Enterococcus faecalis polynucleotides and polypeptides
AU7376698A (en) 1997-05-09 1998-11-27 Smithkline Beecham Corporation Integrin ligand, human mindin
ES2312205T3 (es) 1998-03-10 2009-02-16 Genentech, Inc. Nuevo polipeptido y acidos nucleicos que lo codifican.
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
JP2002527757A (ja) * 1998-10-19 2002-08-27 ダイアデクスアス・インコーポレーテッド 前立腺癌を診断、監視、病期分類、イメージング及び治療する方法
US6960433B1 (en) * 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
EE05627B1 (et) * 1998-12-23 2013-02-15 Pfizer Inc. CTLA-4 vastased inimese monoklonaalsed antikehad
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels
DE202012012998U1 (de) 2011-08-31 2014-06-13 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

Also Published As

Publication number Publication date
NO20022836D0 (no) 2002-06-14
EE05293B1 (et) 2010-04-15
US20020004047A1 (en) 2002-01-10
DE60042836D1 (de) 2009-10-08
HU229001B1 (en) 2013-07-29
HRP20020549A2 (en) 2004-04-30
SI1237915T1 (sl) 2009-12-31
US20040152139A1 (en) 2004-08-05
AU784674B2 (en) 2006-05-25
WO2001044291A2 (en) 2001-06-21
ES2331106T3 (es) 2009-12-22
IL150115A0 (en) 2002-12-01
EP2048157B1 (en) 2012-10-10
MXPA02005914A (es) 2003-02-27
SI21140A (sl) 2003-08-31
IL150115A (en) 2013-11-28
LT2002070A (en) 2003-04-25
CN1434832A (zh) 2003-08-06
EP1237915B1 (en) 2009-08-26
PL207634B1 (pl) 2011-01-31
ATE440862T1 (de) 2009-09-15
RO122543B1 (ro) 2009-08-28
CA2394574A1 (en) 2001-06-21
BG65898B1 (bg) 2010-04-30
RU2002119208A (ru) 2004-02-27
AU3074601A (en) 2001-06-25
SK8482002A3 (en) 2003-02-04
HUP0204224A3 (en) 2004-12-28
PL356220A1 (en) 2004-06-28
NO20022836L (no) 2002-08-15
KR20020065575A (ko) 2002-08-13
KR100752434B1 (ko) 2007-08-27
BR0017022A (pt) 2002-11-05
CZ299232B6 (cs) 2008-05-21
US6682902B2 (en) 2004-01-27
CN1297566C (zh) 2007-01-31
LT5046B (lt) 2003-08-25
YU44602A (sh) 2005-06-10
HUP0204224A2 (hu) 2003-03-28
BG106823A (bg) 2003-04-30
US7307154B2 (en) 2007-12-11
RU2283130C2 (ru) 2006-09-10
JP4979867B2 (ja) 2012-07-18
EP1237915A2 (en) 2002-09-11
MEP37808A (en) 2011-05-10
US20040023307A1 (en) 2004-02-05
WO2001044291A3 (en) 2002-01-17
DK1237915T3 (da) 2009-11-16
NO330924B1 (no) 2011-08-22
ZA200205638B (en) 2003-10-15
JP2003521244A (ja) 2003-07-15
US20090214422A1 (en) 2009-08-27
EP2048157A1 (en) 2009-04-15
NZ519598A (en) 2004-03-26
HRP20020549B1 (hr) 2013-09-30
US7887804B2 (en) 2011-02-15
EE200200323A (et) 2003-10-15
US7893217B2 (en) 2011-02-22
PT1237915E (pt) 2009-11-04
RS50831B (sr) 2010-08-31
US20090292112A1 (en) 2009-11-26
SK288147B6 (sk) 2013-12-02

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20141215