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SK14602002A3 - Spôsob výroby citalopramu a medziprodukty - Google Patents

Spôsob výroby citalopramu a medziprodukty Download PDF

Info

Publication number
SK14602002A3
SK14602002A3 SK1460-2002A SK14602002A SK14602002A3 SK 14602002 A3 SK14602002 A3 SK 14602002A3 SK 14602002 A SK14602002 A SK 14602002A SK 14602002 A3 SK14602002 A3 SK 14602002A3
Authority
SK
Slovakia
Prior art keywords
cyano
group
formula
compound
followed
Prior art date
Application number
SK1460-2002A
Other languages
English (en)
Slovak (sk)
Inventor
Hans Petersen
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of SK14602002A3 publication Critical patent/SK14602002A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
SK1460-2002A 2000-03-13 2001-03-13 Spôsob výroby citalopramu a medziprodukty SK14602002A3 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200000401 2000-03-13
DKPA200000415 2000-03-14
PCT/DK2001/000168 WO2001068631A1 (en) 2000-03-13 2001-03-13 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
SK14602002A3 true SK14602002A3 (sk) 2003-02-04

Family

ID=26068790

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1460-2002A SK14602002A3 (sk) 2000-03-13 2001-03-13 Spôsob výroby citalopramu a medziprodukty

Country Status (22)

Country Link
US (2) US6762308B2 (zh)
EP (1) EP1265883A1 (zh)
JP (1) JP2003527387A (zh)
KR (1) KR20020080481A (zh)
CN (1) CN1429219A (zh)
AU (1) AU2001242298A1 (zh)
BG (1) BG107047A (zh)
BR (1) BR0109176A (zh)
CA (1) CA2402388A1 (zh)
CZ (1) CZ20023384A3 (zh)
EA (1) EA200200969A1 (zh)
HR (1) HRP20020744A2 (zh)
HU (1) HUP0300274A2 (zh)
IL (1) IL151490A0 (zh)
IS (1) IS6529A (zh)
MX (1) MXPA02008869A (zh)
NO (1) NO20024213L (zh)
NZ (1) NZ521201A (zh)
PL (1) PL360110A1 (zh)
SK (1) SK14602002A3 (zh)
TR (1) TR200202166T2 (zh)
WO (1) WO2001068631A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69907037T3 (de) * 1999-04-14 2010-02-18 H. Lundbeck A/S Verfahren zur herstellung von citalopram
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
CA2402553A1 (en) * 2000-03-13 2001-09-20 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
HUP0300178A2 (en) 2000-03-14 2003-05-28 Lundbeck & Co As H Method for the preparation of citalopram
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
US7613106B2 (en) * 2005-01-04 2009-11-03 Avaya Inc. Dial plan transparency for fragmented networks
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (zh) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
AU737610B2 (en) 1997-07-08 2001-08-23 H. Lundbeck A/S Method for the preparation of citalopram
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
TR200001341T2 (tr) 1997-11-11 2000-11-21 H. Lundbeck A/S Sitalopramın hazırlandığı metot
ES2189502T3 (es) 1998-10-20 2003-07-01 Lundbeck & Co As H Metodo para la prevencion de citalopram.
UA70979C2 (uk) 1998-12-23 2004-11-15 Х. Луннбек А/С Спосіб одержання 5-ціанофталіду
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DE69907037T3 (de) 1999-04-14 2010-02-18 H. Lundbeck A/S Verfahren zur herstellung von citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
PL355532A1 (en) 1999-12-28 2004-05-04 H.Lundbeck A/S Method for the preparation of citalopram
AU1858400A (en) 1999-12-30 2001-07-16 H. Lundbeck A/S Method for the preparation of citalopram
KR100660802B1 (ko) 2000-01-14 2006-12-26 하. 룬트벡 아크티에 셀스카브 5-시아노프탈리드의 제조 방법
US6433196B1 (en) 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
HUP0300178A2 (en) 2000-03-14 2003-05-28 Lundbeck & Co As H Method for the preparation of citalopram
IL151487A0 (en) 2000-03-16 2003-04-10 Lundbeck & Co As H Method for the preparation of 5-cyano-1-(4-flourophenyl)-1,3-dihydroisobenzofurans
CZ2002832A3 (cs) 2000-07-06 2002-05-15 H. Lundbeck A/S Způsob výroby citalopramu
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
BR0106272A (pt) 2000-12-22 2004-06-15 Lundbeck & Co As H Processo para preparação de citalopram puro
CN1366526A (zh) 2000-12-28 2002-08-28 H·隆德贝克有限公司 纯西酞普兰的制备方法

Also Published As

Publication number Publication date
TR200202166T2 (tr) 2002-12-23
CA2402388A1 (en) 2001-09-20
NO20024213D0 (no) 2002-09-04
IL151490A0 (en) 2003-04-10
CZ20023384A3 (cs) 2003-01-15
IS6529A (is) 2002-08-27
BR0109176A (pt) 2003-04-22
NO20024213L (no) 2002-11-13
EA200200969A1 (ru) 2003-02-27
PL360110A1 (en) 2004-09-06
WO2001068631A1 (en) 2001-09-20
BG107047A (en) 2003-04-30
US6992198B2 (en) 2006-01-31
US20040215025A1 (en) 2004-10-28
MXPA02008869A (es) 2003-02-10
HUP0300274A2 (hu) 2003-06-28
JP2003527387A (ja) 2003-09-16
KR20020080481A (ko) 2002-10-23
HRP20020744A2 (en) 2004-12-31
AU2001242298A1 (en) 2001-09-24
CN1429219A (zh) 2003-07-09
EP1265883A1 (en) 2002-12-18
US20030092919A1 (en) 2003-05-15
US6762308B2 (en) 2004-07-13
NZ521201A (en) 2004-02-27

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