|
MXPA03009566A
(es)
*
|
2001-04-19 |
2004-12-06 |
Scripps Research Inst |
Metodos y composicion para la produccion de pares trna-aminoaciltrna sintetasa ortogonales.
|
|
DE60329700D1
(en)
*
|
2002-10-16 |
2009-11-26 |
Scripps Research Inst |
Glycoproteinsynthese
|
|
CN103289960B
(zh)
|
2003-04-17 |
2017-04-26 |
斯克利普斯研究院 |
扩展真核生物遗传密码
|
|
EP2392923B1
(en)
|
2003-06-18 |
2014-05-21 |
The Scripps Research Institute |
Method of producing proteins comprising unnatural amino acid
|
|
SI1666604T1
(sl)
*
|
2003-07-07 |
2008-08-31 |
Scripps Research Inst |
Sestavki ortogonalnih parov lizil-tRNA in aminoacil-tRNA in aminoacil-tRNA-sintetaze in njihove uporabe
|
|
US8008041B2
(en)
|
2003-10-14 |
2011-08-30 |
The Scripps Research Institute |
Site-specific incorporation of redox active amino acids into proteins
|
|
SG135176A1
(en)
|
2004-02-02 |
2007-09-28 |
Ambrx Inc |
Modified human four helical bundle polypeptides and their uses
|
|
AU2005248392A1
(en)
*
|
2004-05-25 |
2005-12-08 |
Irm, Llc |
Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for crystal structure determination
|
|
CN102603895B
(zh)
|
2004-06-18 |
2016-09-28 |
Ambrx公司 |
新颖抗原结合多肽和其用途
|
|
WO2006091231A2
(en)
|
2004-07-21 |
2006-08-31 |
Ambrx, Inc. |
Biosynthetic polypeptides utilizing non-naturally encoded amino acids
|
|
US7718410B2
(en)
|
2004-09-21 |
2010-05-18 |
The Scripps Research Institute |
In vivo incorporation of alkynyl amino acids into proteins in eubacteria
|
|
US20080171317A1
(en)
*
|
2004-09-22 |
2008-07-17 |
The Scripps Research Institute |
Site-Specific Labeling of Proteins for Nmr Studies
|
|
US20080064059A1
(en)
|
2004-10-20 |
2008-03-13 |
Scripps Research Institute |
In Vivo Site-Specific Incorporation of N-Acetyl-Galactosamine Amino Acids in Eubacteria
|
|
EP2383340B1
(en)
|
2004-10-27 |
2014-07-16 |
The Scripps Research Institute |
Orthogonal translation components for the in vivo incorporation of unnatural amino acids
|
|
WO2006073846A2
(en)
|
2004-12-22 |
2006-07-13 |
Ambrx, Inc. |
Methods for expression and purification of recombinant human growth hormone
|
|
MX2007007581A
(es)
|
2004-12-22 |
2007-07-24 |
Ambrx Inc |
Composiciones de amino acil-arnt sintetasa y sus usos.
|
|
CN103690936A
(zh)
|
2004-12-22 |
2014-04-02 |
Ambrx公司 |
经修饰的人类生长激素
|
|
US7816320B2
(en)
|
2004-12-22 |
2010-10-19 |
Ambrx, Inc. |
Formulations of human growth hormone comprising a non-naturally encoded amino acid at position 35
|
|
CN101247821B
(zh)
|
2005-06-03 |
2013-01-23 |
Ambrx公司 |
经改良人类干扰素分子和其用途
|
|
KR20080069993A
(ko)
|
2005-10-12 |
2008-07-29 |
더 스크립스 리서치 인스티튜트 |
파지-디스플레이된 폴리펩티드의 선별적인 번역후 변형
|
|
KR20080079643A
(ko)
|
2005-11-16 |
2008-09-01 |
암브룩스, 인코포레이티드 |
비-천연 아미노산을 포함하는 방법 및 조성물
|
|
EP1963536B1
(en)
|
2005-12-22 |
2016-05-04 |
Pacific Biosciences of California, Inc. |
Polymerases for nucleotide analogue incorporation
|
|
EP1991680B1
(en)
*
|
2006-03-09 |
2013-08-21 |
The Scripps Research Institute |
System for the expression of orthogonal translation components in eubacterial host cells
|
|
MX2008011669A
(es)
|
2006-03-16 |
2008-09-22 |
Scripps Research Inst |
Expresion programada geneticamente de proteinas que contienen el aminoacido no natural fenilselenocisteina.
|
|
WO2007139870A1
(en)
*
|
2006-05-23 |
2007-12-06 |
The Scripps Research Institute |
Genetically encoded fluorescent coumarin amino acids
|
|
EP2064333B1
(en)
|
2006-09-08 |
2014-02-26 |
Ambrx, Inc. |
Suppressor trna transcription in vertebrate cells
|
|
CA2663083A1
(en)
|
2006-09-08 |
2008-03-13 |
Ambrx, Inc. |
Modified human plasma polypeptide or fc scaffolds and their uses
|
|
US8114652B2
(en)
|
2006-09-21 |
2012-02-14 |
The Scripps Research Institute |
Genetically programmed expression of selectively sulfated proteins in eubacteria
|
|
RU2009112104A
(ru)
|
2006-10-18 |
2010-11-27 |
Зе Скрипс Ресеч Инститьют (Us) |
Генетическое встраивание не встречающихся в природе аминокислот в белки клеток млекопитающих
|
|
BRPI0809583B1
(pt)
|
2007-03-30 |
2022-02-22 |
Ambrx, Inc |
Polipeptídeo fgf-21 modificado, composição compreendendo o mesmo, método para produzir o referido polipetídeo fgf-21 e célula compreendendo um polinucleotídeo
|
|
MX2009011870A
(es)
|
2007-05-02 |
2009-11-12 |
Ambrx Inc |
Polipeptidos de interferon beta modificados y usos de los mismos.
|
|
CN102203257B
(zh)
*
|
2007-10-25 |
2014-01-08 |
斯克利普斯研究院 |
3-氨基酪氨酸遗传掺入还原酶
|
|
WO2009059056A2
(en)
*
|
2007-11-02 |
2009-05-07 |
The Scripps Research Institute |
A genetically encoded boronate amino acid
|
|
BRPI0819092A2
(pt)
*
|
2007-11-02 |
2014-10-14 |
Scripps Research Inst |
Evolução direcionada usando proteínas que compreendem aminoácidos não naturais.
|
|
ES2632504T3
(es)
|
2007-11-20 |
2017-09-13 |
Ambrx, Inc. |
Polipéptidos de insulina modificados y sus usos
|
|
JP2011527886A
(ja)
|
2007-12-11 |
2011-11-10 |
ザ スクリプス リサーチ インスティチュート |
メタノール資化性酵母ピキア・パストリスにおけるインビボ非天然アミノ酸発現
|
|
BRPI0906388A2
(pt)
*
|
2008-02-08 |
2015-07-07 |
Scripps Research Inst |
Quebra de tolerância imunológica com um aminoácido não natural geneticamente codificado
|
|
NZ620606A
(en)
|
2008-02-08 |
2015-08-28 |
Ambrx Inc |
Modified leptin polypeptides and their uses
|
|
WO2009151491A2
(en)
*
|
2008-02-27 |
2009-12-17 |
The Scripps Research Institute |
In vivo incorporation of an unnatural amino acid comprising a 1,2-aminothiol group
|
|
ES2614078T3
(es)
|
2008-03-31 |
2017-05-29 |
Pacific Biosciences Of California, Inc. |
Generación de polimerasas modificadas para precisión mejorada en secuenciación de una única molécula
|
|
PE20110426A1
(es)
|
2008-07-23 |
2011-07-01 |
Ambrx Inc |
Polipeptidos g-csf bovinos modificados
|
|
CN102232085A
(zh)
|
2008-09-26 |
2011-11-02 |
Ambrx公司 |
修饰的动物促红细胞生成素多肽和其用途
|
|
PT2337846T
(pt)
|
2008-09-26 |
2018-04-05 |
Ambrx Inc |
Vacinas e microrganismos dependentes da replicação de aminoácidos não naturais
|
|
CN102307905B
(zh)
*
|
2008-12-10 |
2015-11-25 |
斯克利普斯研究院 |
利用化学反应性非天然氨基酸产生载体-肽偶联物
|
|
US20090197339A1
(en)
*
|
2008-12-10 |
2009-08-06 |
The Scripps Research Institute |
In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris
|
|
WO2011087810A1
(en)
|
2009-12-21 |
2011-07-21 |
Ambrx, Inc. |
Modified porcine somatotropin polypeptides and their uses
|
|
JP2013515080A
(ja)
|
2009-12-21 |
2013-05-02 |
アンブルックス,インコーポレイテッド |
修飾されているウシのソマトトロピンポリペプチドおよびそれらの使用
|
|
AU2011248625B2
(en)
|
2010-04-26 |
2017-01-05 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase
|
|
CA2797259C
(en)
|
2010-04-27 |
2020-09-29 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl trna synthetases
|
|
WO2011139799A2
(en)
|
2010-04-27 |
2011-11-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl trna synthetases
|
|
CN103097524B
(zh)
|
2010-04-28 |
2016-08-03 |
Atyr医药公司 |
与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
|
|
CA2797393C
(en)
|
2010-04-29 |
2020-03-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases
|
|
US9068177B2
(en)
|
2010-04-29 |
2015-06-30 |
Atyr Pharma, Inc |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases
|
|
CN103097523B
(zh)
|
2010-04-29 |
2016-09-28 |
Atyr医药公司 |
与天冬酰胺酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
|
|
CN103096925A
(zh)
|
2010-05-03 |
2013-05-08 |
Atyr医药公司 |
与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
|
|
WO2011140132A2
(en)
|
2010-05-03 |
2011-11-10 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases
|
|
JP6008841B2
(ja)
|
2010-05-03 |
2016-10-19 |
エータイアー ファーマ, インコーポレイテッド |
メチオニルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
AU2011248357B2
(en)
|
2010-05-03 |
2017-02-23 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-tRNA synthetases
|
|
CN102985103A
(zh)
|
2010-05-04 |
2013-03-20 |
Atyr医药公司 |
与p38多-tRNA合成酶复合物相关的治疗、诊断和抗体组合物的创新发现
|
|
US9062301B2
(en)
|
2010-05-04 |
2015-06-23 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-tRNA synthetases
|
|
US8945541B2
(en)
|
2010-05-14 |
2015-02-03 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases
|
|
JP6027965B2
(ja)
|
2010-05-17 |
2016-11-16 |
エータイアー ファーマ, インコーポレイテッド |
ロイシルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
JP5906237B2
(ja)
|
2010-06-01 |
2016-04-20 |
エータイアー ファーマ, インコーポレイテッド |
リジルtRNA合成酵素のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
|
|
CN103118695B
(zh)
|
2010-07-12 |
2016-08-03 |
Atyr医药公司 |
与甘氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现
|
|
CA2804278C
(en)
|
2010-07-12 |
2021-07-13 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases
|
|
US8999321B2
(en)
|
2010-07-12 |
2015-04-07 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
|
|
WO2012021249A2
(en)
|
2010-07-12 |
2012-02-16 |
Atyr Pharma, Inc. |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
|
|
AU2011291943B2
(en)
|
2010-08-17 |
2015-01-22 |
Ambrx, Inc. |
Modified relaxin polypeptides and their uses
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
WO2012027611A2
(en)
|
2010-08-25 |
2012-03-01 |
Atyr Pharma, Inc. |
INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF TYROSYL-tRNA SYNTHETASES
|
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
|
AU2011311956C1
(en)
|
2010-10-06 |
2017-06-15 |
Pangu Biopharma Limited |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl tRNA synthetases
|
|
US20130078671A1
(en)
*
|
2011-03-25 |
2013-03-28 |
The Texas A&M University System |
Incorporation of two different noncanonical amino acids into a single protein
|
|
US10323236B2
(en)
|
2011-07-22 |
2019-06-18 |
President And Fellows Of Harvard College |
Evaluation and improvement of nuclease cleavage specificity
|
|
WO2013022982A2
(en)
|
2011-08-09 |
2013-02-14 |
Atyr Pharma, Inc. |
Pegylated tyrosyl-trna synthetase polypeptides
|
|
WO2013086216A1
(en)
|
2011-12-06 |
2013-06-13 |
Atyr Pharma, Inc. |
Improved aspartyl-trna synthetases
|
|
WO2013086228A1
(en)
|
2011-12-06 |
2013-06-13 |
Atyr Pharma, Inc. |
Pegylated aspartyl-trna synthetase polypeptides
|
|
CN102517241B
(zh)
*
|
2011-12-19 |
2013-06-19 |
中国药科大学 |
一种含有d型氨基酸的双羰基还原酶的突变体的制备方法
|
|
JP6169608B2
(ja)
|
2011-12-29 |
2017-07-26 |
エータイアー ファーマ, インコーポレイテッド |
アスパルチルtRNAシンテターゼ−Fcコンジュゲート
|
|
CN108410827B
(zh)
*
|
2012-05-18 |
2023-05-09 |
英国研究与创新署 |
整合包含bcn基团的氨基酸到多肽中的方法
|
|
JO3564B1
(ar)
|
2013-03-08 |
2020-07-05 |
Novartis Ag |
ببتيدات وتركيبات لعلاج ضرر المفاصل
|
|
JP6397479B2
(ja)
|
2013-03-15 |
2018-09-26 |
エータイアー ファーマ, インコーポレイテッド |
ヒスチジル−tRNAシンテターゼFcコンジュゲート
|
|
CN104099360A
(zh)
*
|
2013-04-12 |
2014-10-15 |
北京大学 |
非天然氨基酸标记的目的蛋白或肽的制备
|
|
EP3021942A4
(en)
|
2013-07-19 |
2017-04-19 |
The Regents of The University of California |
Milk fat globule epidermal growth factor 8 regulates fatty acid uptake
|
|
US9163284B2
(en)
|
2013-08-09 |
2015-10-20 |
President And Fellows Of Harvard College |
Methods for identifying a target site of a Cas9 nuclease
|
|
US9359599B2
(en)
|
2013-08-22 |
2016-06-07 |
President And Fellows Of Harvard College |
Engineered transcription activator-like effector (TALE) domains and uses thereof
|
|
US9340799B2
(en)
|
2013-09-06 |
2016-05-17 |
President And Fellows Of Harvard College |
MRNA-sensing switchable gRNAs
|
|
US9322037B2
(en)
|
2013-09-06 |
2016-04-26 |
President And Fellows Of Harvard College |
Cas9-FokI fusion proteins and uses thereof
|
|
US9526784B2
(en)
|
2013-09-06 |
2016-12-27 |
President And Fellows Of Harvard College |
Delivery system for functional nucleases
|
|
US20150165054A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting caspase-9 point mutations
|
|
US10077453B2
(en)
|
2014-07-30 |
2018-09-18 |
President And Fellows Of Harvard College |
CAS9 proteins including ligand-dependent inteins
|
|
SG11201702824UA
(en)
|
2014-10-24 |
2017-05-30 |
Bristol Myers Squibb Co |
Modified fgf-21 polypeptides and uses thereof
|
|
SG10201906059VA
(en)
|
2015-07-30 |
2019-08-27 |
Macrogenics Inc |
Pd-1-binding molecules and methods of use thereof
|
|
US10167457B2
(en)
|
2015-10-23 |
2019-01-01 |
President And Fellows Of Harvard College |
Nucleobase editors and uses thereof
|
|
CR20180318A
(es)
|
2015-12-14 |
2018-09-19 |
Macrogenics Inc |
Moléculas biespecíficas que tienen inmunorreactividad con pd-1 y ctla-4, y métodos de uso de las mismas
|
|
KR20250103795A
(ko)
|
2016-08-03 |
2025-07-07 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
EP3497214B1
(en)
|
2016-08-09 |
2023-06-28 |
President and Fellows of Harvard College |
Programmable cas9-recombinase fusion proteins and uses thereof
|
|
WO2018039438A1
(en)
|
2016-08-24 |
2018-03-01 |
President And Fellows Of Harvard College |
Incorporation of unnatural amino acids into proteins using base editing
|
|
AU2017342543B2
(en)
|
2016-10-14 |
2024-06-27 |
President And Fellows Of Harvard College |
AAV delivery of nucleobase editors
|
|
CN109963579A
(zh)
|
2016-11-14 |
2019-07-02 |
诺华股份有限公司 |
用于治疗软骨损伤和关节炎的方法和组合物
|
|
US10745677B2
(en)
|
2016-12-23 |
2020-08-18 |
President And Fellows Of Harvard College |
Editing of CCR5 receptor gene to protect against HIV infection
|
|
KR102670432B1
(ko)
|
2017-02-08 |
2024-05-28 |
브리스톨-마이어스 스큅 컴퍼니 |
약동학적 인핸서를 포함하는 변형된 렐락신 폴리펩티드 및 그의 용도
|
|
EP3592853A1
(en)
|
2017-03-09 |
2020-01-15 |
President and Fellows of Harvard College |
Suppression of pain by gene editing
|
|
US12390514B2
(en)
|
2017-03-09 |
2025-08-19 |
President And Fellows Of Harvard College |
Cancer vaccine
|
|
US11542496B2
(en)
|
2017-03-10 |
2023-01-03 |
President And Fellows Of Harvard College |
Cytosine to guanine base editor
|
|
BR112019019655A2
(pt)
|
2017-03-23 |
2020-04-22 |
Harvard College |
editores de nucleobase que compreendem proteínas de ligação a dna programáveis por ácido nucleico
|
|
CA3060514A1
(en)
|
2017-04-20 |
2018-10-25 |
Atyr Pharma, Inc. |
Compositions and methods for treating lung inflammation
|
|
WO2018209320A1
(en)
|
2017-05-12 |
2018-11-15 |
President And Fellows Of Harvard College |
Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation
|
|
US11732274B2
(en)
|
2017-07-28 |
2023-08-22 |
President And Fellows Of Harvard College |
Methods and compositions for evolving base editors using phage-assisted continuous evolution (PACE)
|
|
US11319532B2
(en)
|
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2022-05-03 |
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|
|
AU2018352592C1
(en)
|
2017-10-16 |
2025-09-25 |
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|
|
US12406749B2
(en)
|
2017-12-15 |
2025-09-02 |
The Broad Institute, Inc. |
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|
|
AU2019233673B2
(en)
|
2018-03-15 |
2025-05-01 |
Arcturus Therapeutics, Inc. |
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|
|
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(en)
|
2018-03-15 |
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|
|
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(zh)
|
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2021-02-02 |
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|
|
EP3788149B1
(en)
|
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|
|
US12157760B2
(en)
|
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|
|
US12522807B2
(en)
|
2018-07-09 |
2026-01-13 |
The Broad Institute, Inc. |
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|
|
SG11202102427XA
(en)
|
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|
|
AU2019361206A1
(en)
|
2018-10-19 |
2021-06-03 |
Ambrx, Inc. |
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|
|
GB201817444D0
(en)
|
2018-10-26 |
2018-12-12 |
Res & Innovation Uk |
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|
|
WO2020092453A1
(en)
|
2018-10-29 |
2020-05-07 |
The Broad Institute, Inc. |
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|
|
US12351837B2
(en)
|
2019-01-23 |
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The Broad Institute, Inc. |
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|
|
CN114127285B
(zh)
|
2019-03-19 |
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布罗德研究所股份有限公司 |
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|
|
CN111718920B
(zh)
*
|
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宁波鲲鹏生物科技有限公司 |
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|
|
LU101182B1
(en)
*
|
2019-04-11 |
2020-10-12 |
Univ Hamburg |
Synthetic transfer RNA with extended anticodon loop
|
|
EP3953469A1
(en)
|
2019-04-11 |
2022-02-16 |
Arcturus Therapeutics, Inc. |
Synthetic transfer rna with extended anticodon loop
|
|
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(en)
|
2019-04-17 |
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The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
CN110172467B
(zh)
*
|
2019-05-24 |
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浙江大学 |
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|
|
US12435330B2
(en)
|
2019-10-10 |
2025-10-07 |
The Broad Institute, Inc. |
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|
|
CA3174114A1
(en)
|
2020-03-11 |
2021-09-16 |
Ambrx, Inc. |
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|
|
DE112021002672T5
(de)
|
2020-05-08 |
2023-04-13 |
President And Fellows Of Harvard College |
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|
|
CN114250243B
(zh)
*
|
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|
|
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(en)
|
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|
|
WO2023281484A1
(en)
|
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|
|
AU2022306788A1
(en)
|
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|
|
US20230201365A1
(en)
|
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|
|
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(en)
|
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|
|
US20240384267A1
(en)
|
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|
|
AU2023226512A1
(en)
|
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|
|
US20240132563A1
(en)
|
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|
|
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(zh)
*
|
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|
|
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(en)
|
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Ada Forsyth Institute, Inc. |
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|
|
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(en)
|
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|
|
CN115975978B
(zh)
*
|
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|
|
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(en)
|
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|
|
WO2025041102A1
(en)
|
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|
|
US20250197467A1
(en)
|
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|