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SI1216048T1 - Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols - Google Patents

Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols

Info

Publication number
SI1216048T1
SI1216048T1 SI200030589T SI200030589T SI1216048T1 SI 1216048 T1 SI1216048 T1 SI 1216048T1 SI 200030589 T SI200030589 T SI 200030589T SI 200030589 T SI200030589 T SI 200030589T SI 1216048 T1 SI1216048 T1 SI 1216048T1
Authority
SI
Slovenia
Prior art keywords
lipases
polyols
inhibitor
fatty acid
acid ester
Prior art date
Application number
SI200030589T
Other languages
English (en)
Slovenian (sl)
Inventor
Smidt Passchier Christiaan De
Paul Hadvary
Hans Lengsfeld
Marcel Schmid
Donald Macfarland Small
Hans Steffen
Joseph Tardio
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8238989&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1216048(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI1216048T1 publication Critical patent/SI1216048T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
SI200030589T 1999-09-13 2000-09-11 Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols SI1216048T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99118179 1999-09-13
PCT/EP2000/008857 WO2001019378A2 (en) 1999-09-13 2000-09-11 Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols
EP00964158A EP1216048B1 (en) 1999-09-13 2000-09-11 Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols

Publications (1)

Publication Number Publication Date
SI1216048T1 true SI1216048T1 (en) 2005-06-30

Family

ID=8238989

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030589T SI1216048T1 (en) 1999-09-13 2000-09-11 Solid lipid formulations comprising an inhibitor of lipases and a fatty acid ester of polyols

Country Status (36)

Country Link
US (1) US6703369B1 (pt)
EP (1) EP1216048B1 (pt)
JP (1) JP4217017B2 (pt)
KR (1) KR100523879B1 (pt)
CN (1) CN1197554C (pt)
AR (1) AR025609A1 (pt)
AT (1) ATE285783T1 (pt)
AU (1) AU769016B2 (pt)
BR (1) BRPI0013940B1 (pt)
CA (1) CA2383036C (pt)
CO (1) CO5210857A1 (pt)
CZ (1) CZ301844B6 (pt)
DE (1) DE60017156T2 (pt)
EG (1) EG24225A (pt)
ES (1) ES2233444T3 (pt)
GC (1) GC0000259A (pt)
HK (1) HK1049798B (pt)
HR (1) HRP20020206B1 (pt)
HU (1) HU229037B1 (pt)
IL (2) IL148570A0 (pt)
JO (1) JO2300B1 (pt)
MA (1) MA26817A1 (pt)
ME (1) MEP90908A (pt)
MX (1) MXPA02002662A (pt)
MY (1) MY127430A (pt)
NO (1) NO328889B1 (pt)
NZ (1) NZ517396A (pt)
PE (1) PE20010661A1 (pt)
PL (1) PL199869B1 (pt)
PT (1) PT1216048E (pt)
RS (1) RS50373B (pt)
RU (1) RU2248218C2 (pt)
SI (1) SI1216048T1 (pt)
TR (1) TR200200605T2 (pt)
WO (1) WO2001019378A2 (pt)
ZA (1) ZA200201249B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas
JP4265911B2 (ja) * 2000-07-28 2009-05-20 エフ．ホフマン−ラ ロシュ アーゲー 新規医薬組成物
US6730319B2 (en) 2001-06-06 2004-05-04 Hoffmann-La Roche Inc. Pharmaceutical compositions having depressed melting points
US20030027786A1 (en) * 2001-06-06 2003-02-06 Karsten Maeder Lipase inhibiting composition
DE10251963A1 (de) * 2002-11-08 2004-05-19 Lts Lohmann Therapie-Systeme Ag Transmucosale pharmazeutische Darreichungsform
US8372430B2 (en) 2002-12-17 2013-02-12 The Procter & Gamble Company Compositions, methods, and kits useful for the alleviation of gastrointestinal effects
WO2004078164A1 (en) * 2003-03-04 2004-09-16 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
FI20045076L (fi) * 2004-03-15 2005-09-16 Bioferme Oy Funktionaalinen elintarvike
RU2375046C2 (ru) * 2004-10-25 2009-12-10 Джапан Тобакко Инк. Твердый состав с улучшенными растворимостью и стабильностью и способ его получения
KR100669497B1 (ko) * 2005-08-17 2007-01-16 보람제약주식회사 안정성과 용출률이 뛰어난 약리학적 조성물 및 그 제조방법
US20070148245A1 (en) * 2005-12-22 2007-06-28 Ilan Zalit Compressed solid dosage forms with drugs of low solubility and process for making the same
EP1808163A1 (en) * 2005-12-22 2007-07-18 Teva Pharmaceutical Industries Ltd. Compressed solid dosage forms with drugs of low solubility and process for making the same
CA2626234A1 (en) * 2005-12-22 2007-06-28 Teva Pharmaceutical Industries Ltd. Compressed solid dosage forms with drugs of low solubility and process for making the same
KR101252635B1 (ko) 2006-04-20 2013-04-10 (주)아모레퍼시픽 리파아제 저해제 및 친유성 오일흡수제를 포함하는 약학조성물 및 이로부터 제조된 경구 투여용 제제
KR100903504B1 (ko) * 2007-05-18 2009-06-17 강태용 비라칸사스 열매 추출물질을 포함하는 기능식품 및 체중 감소제
EP2076248A2 (en) * 2007-08-17 2009-07-08 Teva Pharmaceutical Industries Ltd. Methods and compositions for controlling the bioavailability of poorly soluble drugs
ATE477820T1 (de) * 2007-09-12 2010-09-15 Mader S R L Pharmazeutische zusammensetzungen zur oralen verabreichung bei der behandlung von adipositas- patienten
PL216542B1 (pl) 2008-03-20 2014-04-30 Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna Sposób wytwarzania stabilnej kompozycji orlistatu w postaci kapsułkowanego proszku
US8309107B2 (en) 2008-10-06 2012-11-13 Banner Pharmacaps, Inc. Stable solutions of orlistat for pharmaceutical dosage forms
BRPI0901602B8 (pt) 2009-04-03 2021-05-25 Ems S/A formulação farmacêuticas
UA107369C2 (en) 2010-02-01 2014-12-25 Lab Bago S A Pharmaceutical composition with anti-obesity activity comprising a premixture of pure orlistat and preparation process
EP2486805A1 (en) * 2011-02-11 2012-08-15 Puratos N.V. An emulsion whippable at room-temperature
PH12013501815A1 (en) * 2011-04-14 2013-10-14 J Oil Mills Inc Palm-based fractionated oil and fat, and oil and fat composition and food product containing the same
CN102552168B (zh) * 2012-01-31 2013-08-07 杭州华东医药集团生物工程研究所有限公司 一种含有奥利司他的药物组合物及其制备方法
GB2501535A (en) 2012-04-26 2013-10-30 Sony Corp Chrominance Processing in High Efficiency Video Codecs
US10328022B2 (en) * 2012-05-31 2019-06-25 Repros Therapeutics Inc. Formulations and methods for vaginal delivery of antiprogestins
EP3062787A1 (en) * 2013-10-28 2016-09-07 Nestec S.A. Monoacylglycerols for use in conjunction with a lipase inhibitor and/or diets low in fat and/or calories
CN115105476B (zh) * 2021-03-23 2023-11-14 山东新时代药业有限公司 一种奥利司他冻干口服制剂及其制备工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247547A (en) 1983-06-22 1988-12-28 Paul Hadvary Leucine derivatives
FR2710264B1 (fr) * 1993-09-21 1995-12-08 Rocher Yves Biolog Vegetale Utilisation pour le traitement des peaux mixtes d'une quantité efficace de substances actives.
WO1998024607A1 (en) * 1996-12-04 1998-06-11 Pincott James S Process and apparatus for making crumb rubber from scrap tyres
DK1017408T3 (da) 1997-02-05 2005-08-01 Hoffmann La Roche Anvendelse af tetrahydrolipstatin i behandling af diabetes type II
US6004996A (en) 1997-02-05 1999-12-21 Hoffman-La Roche Inc. Tetrahydrolipstatin containing compositions
US6267952B1 (en) 1998-01-09 2001-07-31 Geltex Pharmaceuticals, Inc. Lipase inhibiting polymers
BR9912979B1 (pt) * 1998-08-14 2010-09-21 composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan.
JP3774118B2 (ja) 1998-08-14 2006-05-10 エフ．ホフマン−ラ ロシュ アーゲー リパーゼ阻害剤を含む製薬学的組成物
AR025609A1 (es) * 1999-09-13 2002-12-04 Hoffmann La Roche Formulaciones lipidas solidas

Also Published As

Publication number Publication date
MY127430A (en) 2006-11-30
CA2383036C (en) 2006-01-10
JO2300B1 (en) 2005-09-12
CN1197554C (zh) 2005-04-20
NO20021205D0 (no) 2002-03-12
HRP20020206B1 (en) 2011-02-28
KR100523879B1 (ko) 2005-10-26
BR0013940A (pt) 2002-05-14
US6703369B1 (en) 2004-03-09
IL148570A (en) 2007-03-08
EP1216048B1 (en) 2004-12-29
NO328889B1 (no) 2010-06-07
ZA200201249B (en) 2003-07-30
CZ20021277A3 (cs) 2003-04-16
HK1049798A1 (en) 2003-05-30
AR025609A1 (es) 2002-12-04
PL199869B1 (pl) 2008-11-28
CA2383036A1 (en) 2001-03-22
RS50373B (sr) 2009-11-10
AU7517700A (en) 2001-04-17
WO2001019378A2 (en) 2001-03-22
MA26817A1 (fr) 2004-12-20
YU13602A (sh) 2006-01-16
PL356154A1 (en) 2004-06-14
RU2002107450A (ru) 2004-01-10
HU229037B1 (en) 2013-07-29
PE20010661A1 (es) 2001-06-25
HUP0202762A2 (hu) 2003-01-28
EP1216048A2 (en) 2002-06-26
ES2233444T3 (es) 2005-06-16
HUP0202762A3 (en) 2005-04-28
ME00675B (me) 2011-12-20
BRPI0013940B1 (pt) 2016-06-21
EG24225A (en) 2008-11-10
HRP20020206A2 (en) 2004-04-30
GC0000259A (en) 2006-11-01
MXPA02002662A (es) 2002-07-30
PT1216048E (pt) 2005-04-29
MEP90908A (en) 2011-12-20
TR200200605T2 (tr) 2002-08-21
CZ301844B6 (cs) 2010-07-07
RU2248218C2 (ru) 2005-03-20
CN1373659A (zh) 2002-10-09
KR20020060177A (ko) 2002-07-16
HK1049798B (zh) 2005-08-05
DE60017156T2 (de) 2006-01-05
NZ517396A (en) 2003-10-31
NO20021205L (no) 2002-03-12
WO2001019378A3 (en) 2001-05-10
JP4217017B2 (ja) 2009-01-28
CO5210857A1 (es) 2002-10-30
ATE285783T1 (de) 2005-01-15
AU769016B2 (en) 2004-01-15
IL148570A0 (en) 2002-09-12
JP2003509373A (ja) 2003-03-11
DE60017156D1 (de) 2005-02-03

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