SG162806A1 - Methods of purifying anti a beta antibodies - Google Patents
Methods of purifying anti a beta antibodiesInfo
- Publication number
- SG162806A1 SG162806A1 SG201004275-2A SG2010042752A SG162806A1 SG 162806 A1 SG162806 A1 SG 162806A1 SG 2010042752 A SG2010042752 A SG 2010042752A SG 162806 A1 SG162806 A1 SG 162806A1
- Authority
- SG
- Singapore
- Prior art keywords
- ass
- methods
- protein
- binding
- binding protein
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 102000014914 Carrier Proteins Human genes 0.000 abstract 4
- 108091008324 binding proteins Proteins 0.000 abstract 4
- 101710120037 Toxin CcdB Proteins 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- -1 cation salt Chemical class 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69182105P | 2005-06-17 | 2005-06-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG162806A1 true SG162806A1 (en) | 2010-07-29 |
Family
ID=37433887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG201004275-2A SG162806A1 (en) | 2005-06-17 | 2006-06-16 | Methods of purifying anti a beta antibodies |
Country Status (25)
Country | Link |
---|---|
US (3) | US7825223B2 (zh) |
EP (3) | EP1896504B1 (zh) |
JP (2) | JP5270337B2 (zh) |
KR (2) | KR101307614B1 (zh) |
CN (3) | CN104926938B (zh) |
AR (2) | AR053632A1 (zh) |
AU (2) | AU2006261185B2 (zh) |
BR (2) | BRPI0611599A2 (zh) |
CA (2) | CA2611816C (zh) |
CR (2) | CR9576A (zh) |
EA (2) | EA201100177A1 (zh) |
EC (1) | ECSP088086A (zh) |
ES (2) | ES2402650T3 (zh) |
IL (2) | IL187642A (zh) |
MA (1) | MA29609B1 (zh) |
MX (2) | MX2007015952A (zh) |
MY (1) | MY144484A (zh) |
NI (1) | NI200700329A (zh) |
NO (2) | NO20076082L (zh) |
NZ (1) | NZ565044A (zh) |
RU (1) | RU2415865C2 (zh) |
SG (1) | SG162806A1 (zh) |
TW (2) | TW200740839A (zh) |
WO (2) | WO2006138737A2 (zh) |
ZA (2) | ZA200710331B (zh) |
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TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7588766B1 (en) | 2000-05-26 | 2009-09-15 | Elan Pharma International Limited | Treatment of amyloidogenic disease |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
HRP20050670A2 (en) * | 2003-02-01 | 2005-12-31 | WYETH Neuralab Limited | Active immunization to generate antibodies to soluble a-beta |
PE20050627A1 (es) * | 2003-05-30 | 2005-08-10 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
WO2006041934A2 (en) * | 2004-10-05 | 2006-04-20 | Neuralab Limited | Methods and compositions for improving recombinant protein production |
EA012162B1 (ru) * | 2004-10-22 | 2009-08-28 | Эмджен Инк. | Способ рефолдинга рекомбинантных антител |
AR052051A1 (es) * | 2004-12-15 | 2007-02-28 | Neuralab Ltd | Anticuerpos ab humanizados usados en mejorar la cognicion |
ES2396555T3 (es) | 2004-12-15 | 2013-02-22 | Janssen Alzheimer Immunotherapy | Anticuerpos que reconocen péptido beta amiloide |
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US8784810B2 (en) * | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
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