SG11202100482UA - Modified meningococcal fhbp polypeptides - Google Patents
Modified meningococcal fhbp polypeptidesInfo
- Publication number
- SG11202100482UA SG11202100482UA SG11202100482UA SG11202100482UA SG11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA
- Authority
- SG
- Singapore
- Prior art keywords
- meningococcal fhbp
- fhbp polypeptides
- modified meningococcal
- modified
- polypeptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18188321.6A EP3607967A1 (fr) | 2018-08-09 | 2018-08-09 | Polypeptides modifiés du méningocoque fhbp |
| PCT/EP2019/071410 WO2020030782A1 (fr) | 2018-08-09 | 2019-08-09 | Polypeptides fhbp méningococciques modifiés |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202100482UA true SG11202100482UA (en) | 2021-02-25 |
Family
ID=63371487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202100482UA SG11202100482UA (en) | 2018-08-09 | 2019-08-09 | Modified meningococcal fhbp polypeptides |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11708394B2 (fr) |
| EP (2) | EP3607967A1 (fr) |
| JP (2) | JP7271654B2 (fr) |
| KR (1) | KR102677445B1 (fr) |
| CN (1) | CN112566657B (fr) |
| AU (1) | AU2019318120B2 (fr) |
| BR (1) | BR112021000988A2 (fr) |
| CA (1) | CA3108355A1 (fr) |
| EA (1) | EA202190184A1 (fr) |
| IL (1) | IL280189B1 (fr) |
| MA (1) | MA53271A (fr) |
| MX (1) | MX2021001610A (fr) |
| SG (1) | SG11202100482UA (fr) |
| WO (1) | WO2020030782A1 (fr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2714248C2 (ru) * | 2014-07-23 | 2020-02-13 | Чилдрен'З Хоспитал Энд Рисёрч Сентер Эт Окленд | Варианты фактор н-связывающего белка и способы их применения |
| GB202013262D0 (en) | 2020-08-25 | 2020-10-07 | Glaxosmithkline Biologicals Sa | Vaccine Composition |
| CN114681601A (zh) * | 2020-12-31 | 2022-07-01 | 基础治疗有限公司 | 脑膜炎奈瑟氏球菌疫苗及其应用 |
| TW202245836A (zh) | 2021-02-19 | 2022-12-01 | 美商賽諾菲巴斯德公司 | 重組ｂ型腦膜炎球菌疫苗 |
| GB202115077D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202115151D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Methods |
| GB202208089D0 (en) * | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| GB202208093D0 (en) * | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| TW202423477A (zh) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物 |
| CN117264031B (zh) * | 2023-11-03 | 2024-01-30 | 烟台派诺生物技术有限公司 | 一种B群脑膜炎奈瑟菌fHBP重组蛋白及其应用 |
| CN118240723B (zh) * | 2024-05-29 | 2024-08-23 | 上海羽冠生物技术有限公司 | 一种通过发酵产生细菌外膜囊泡的方法 |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4057685A (en) | 1972-02-02 | 1977-11-08 | Abbott Laboratories | Chemically modified endotoxin immunizing agent |
| DE2848965A1 (de) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4882317A (en) | 1984-05-10 | 1989-11-21 | Merck & Co., Inc. | Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| IT1187753B (it) | 1985-07-05 | 1987-12-23 | Sclavo Spa | Coniugati glicoproteici ad attivita' immunogenica trivalente |
| NL8802046A (nl) | 1988-08-18 | 1990-03-16 | Gen Electric | Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen. |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| CA2006700A1 (fr) | 1989-01-17 | 1990-07-17 | Antonello Pessi | Peptides synthetiques et leur utilisation comme porteurs universels pour la preparation de conjugats immunogenes convenant a la mise au point de vaccins synthetiques |
| WO1991001146A1 (fr) | 1989-07-14 | 1991-02-07 | Praxis Biologics, Inc. | Cytokine et supports d'hormone pour vaccins conjugues |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| SE466259B (sv) | 1990-05-31 | 1992-01-20 | Arne Forsgren | Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal |
| IL98715A0 (en) | 1990-08-13 | 1992-07-15 | American Cyanamid Co | Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| DE122009000058I1 (de) | 1993-09-22 | 2009-12-31 | Jackson H M Found Military Med | Verfahren zur aktivierung von löslichem kohlenhydraten durch verwendung von neuen cyanylierungsreagenzien, zur herstellung von immunogenischen konstrukten |
| US6180111B1 (en) | 1995-05-18 | 2001-01-30 | University Of Maryland | Vaccine delivery system |
| GB9711964D0 (en) | 1997-06-09 | 1997-08-06 | Medical Res Council | Live attenuated vaccines |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| JP2004505885A (ja) | 1998-08-19 | 2004-02-26 | ノース アメリカン ワクチン， インコーポレイテッド | Ｎ−アクリロイル化ポリサッカリドを用いて産生されたワクチンとして有用な免疫原性β−プロピオンアミド連結ポリサッカリド−タンパク質結合体 |
| AU1626199A (en) | 1998-12-04 | 2000-06-26 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | A vi-repa conjugate vaccine for immunization against salmonella typhi |
| JP2002541808A (ja) | 1999-04-09 | 2002-12-10 | テクラブ， インコーポレイテッド | ポリサッカリド結合体ワクチンのための組換えトキシンａタンパク質キャリア |
| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| WO2001034642A2 (fr) | 1999-11-12 | 2001-05-17 | University Of Iowa Research Foundation | Commande de la synthese de membrane de neisseria |
| DK1248647T3 (da) | 2000-01-17 | 2010-09-27 | Novartis Vaccines & Diagnostic | Ydre membranvesikel (OMV) vaccine omfattende N. meningitidis serogruppe B ydre membranproteiner |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| NO20002828D0 (no) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav |
| ES2519440T3 (es) | 2000-07-27 | 2014-11-07 | Children's Hospital & Research Center At Oakland | Vacunas para la protección de amplio espectro contra enfermedades causadas por Neisseria meningitidis |
| GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| DE60139563D1 (de) | 2000-10-27 | 2009-09-24 | Craig J Venter Inst Inc | Nukleinsäuren und proteine von gruppen a und b-streptokokken |
| GB0103171D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| US20030035806A1 (en) | 2001-05-11 | 2003-02-20 | D'ambra Anello J. | Novel meningitis conjugate vaccine |
| CA2452720C (fr) | 2001-07-26 | 2012-04-17 | Chiron S.R.L. | Vaccins comprenant des adjuvants aluminium et histidine |
| KR20050039839A (ko) | 2002-08-02 | 2005-04-29 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Ｌｇｔｂ- 나이세리아 메닌기티디스로부터의 ｌ2 및/또는ｌ3 면역유형 리포올리고사카라이드를 포함하는 백신 조성물 |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| WO2004046177A2 (fr) | 2002-11-15 | 2004-06-03 | Chiron Srl | Proteines de surface inattendues sur le meningocoque |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| PL2682126T3 (pl) | 2005-01-27 | 2017-07-31 | Children's Hospital & Research Center At Oakland | Szczepionki pęcherzykowe oparte na GNA1870 dla szerokiego spektrum ochrony przeciwko chorobom spowodowanym przez Neisseria meningitidis |
| US8679770B2 (en) | 2005-09-05 | 2014-03-25 | Glaxo Smith Kline Biologicals S.A. | Serum bactericidal assay for N. meningitidis specific antisera |
| GB0819633D0 (en) | 2008-10-25 | 2008-12-03 | Isis Innovation | Composition |
| GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
| BR112012010531A2 (pt) * | 2009-10-27 | 2019-09-24 | Novartis Ag | "polipeptídeos de modificação meningocócica fhbp" |
| EP2552942B1 (fr) * | 2010-03-30 | 2017-12-27 | Children's Hospital & Research Center at Oakland | Protéines de liaison du facteur h (fhbp) avec des propriétés altérées et leurs procédés d'utilisation |
| MX2014002375A (es) | 2011-08-31 | 2014-09-15 | Children S Hospital & Res Ct Oakland | Secuencias diseñadas para facilitar la expresion de antigenos en neisseria y metodos de uso. |
| CN104114706A (zh) | 2012-02-02 | 2014-10-22 | 诺华股份有限公司 | 用于脑膜炎球菌中增加的蛋白表达的启动子 |
| WO2015128480A1 (fr) | 2014-02-28 | 2015-09-03 | Novartis Ag | Polypeptides fhbp méningococciques modifiés |
| WO2016008960A1 (fr) * | 2014-07-17 | 2016-01-21 | Glaxosmithkline Biologicals S.A. | Polypeptides fhbp méningococciques modifiés |
| AR101225A1 (es) * | 2014-07-17 | 2016-11-30 | Glaxosmithkline Biologicals Sa | Vacunas de meningococos |
| RU2714248C2 (ru) | 2014-07-23 | 2020-02-13 | Чилдрен'З Хоспитал Энд Рисёрч Сентер Эт Окленд | Варианты фактор н-связывающего белка и способы их применения |
-
2018
- 2018-08-09 EP EP18188321.6A patent/EP3607967A1/fr not_active Ceased
-
2019
- 2019-08-08 IL IL280189A patent/IL280189B1/en unknown
- 2019-08-09 US US17/265,610 patent/US11708394B2/en active Active
- 2019-08-09 WO PCT/EP2019/071410 patent/WO2020030782A1/fr unknown
- 2019-08-09 MA MA053271A patent/MA53271A/fr unknown
- 2019-08-09 CN CN201980053356.2A patent/CN112566657B/zh active Active
- 2019-08-09 SG SG11202100482UA patent/SG11202100482UA/en unknown
- 2019-08-09 BR BR112021000988-4A patent/BR112021000988A2/pt unknown
- 2019-08-09 EP EP19758346.1A patent/EP3833388A1/fr active Pending
- 2019-08-09 JP JP2021506665A patent/JP7271654B2/ja active Active
- 2019-08-09 EA EA202190184A patent/EA202190184A1/ru unknown
- 2019-08-09 CA CA3108355A patent/CA3108355A1/fr active Pending
- 2019-08-09 MX MX2021001610A patent/MX2021001610A/es unknown
- 2019-08-09 KR KR1020217006606A patent/KR102677445B1/ko active Active
- 2019-08-09 AU AU2019318120A patent/AU2019318120B2/en active Active
-
2023
- 2023-01-27 JP JP2023010597A patent/JP2023061971A/ja active Pending
- 2023-06-02 US US18/328,162 patent/US20240228551A9/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019318120A1 (en) | 2021-02-11 |
| CN112566657B (zh) | 2025-03-14 |
| IL280189A (en) | 2021-03-01 |
| CN112566657A (zh) | 2021-03-26 |
| WO2020030782A1 (fr) | 2020-02-13 |
| US20240228551A9 (en) | 2024-07-11 |
| JP2023061971A (ja) | 2023-05-02 |
| CA3108355A1 (fr) | 2020-02-13 |
| IL280189B1 (en) | 2025-01-01 |
| EA202190184A1 (ru) | 2021-05-14 |
| MX2021001610A (es) | 2021-04-19 |
| US20240132550A1 (en) | 2024-04-25 |
| EP3833388A1 (fr) | 2021-06-16 |
| MA53271A (fr) | 2021-11-17 |
| US20210277069A1 (en) | 2021-09-09 |
| AU2019318120B2 (en) | 2024-03-14 |
| EP3607967A1 (fr) | 2020-02-12 |
| JP7271654B2 (ja) | 2023-05-11 |
| KR102677445B1 (ko) | 2024-06-20 |
| JP2021533748A (ja) | 2021-12-09 |
| KR20210041594A (ko) | 2021-04-15 |
| US11708394B2 (en) | 2023-07-25 |
| BR112021000988A2 (pt) | 2021-04-27 |
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