SG11202100482UA - Modified meningococcal fhbp polypeptides - Google Patents
Modified meningococcal fhbp polypeptidesInfo
- Publication number
- SG11202100482UA SG11202100482UA SG11202100482UA SG11202100482UA SG11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA SG 11202100482U A SG11202100482U A SG 11202100482UA
- Authority
- SG
- Singapore
- Prior art keywords
- meningococcal fhbp
- fhbp polypeptides
- modified meningococcal
- modified
- polypeptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18188321.6A EP3607967A1 (en) | 2018-08-09 | 2018-08-09 | Modified meningococcal fhbp polypeptides |
| PCT/EP2019/071410 WO2020030782A1 (en) | 2018-08-09 | 2019-08-09 | Modified meningococcal fhbp polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202100482UA true SG11202100482UA (en) | 2021-02-25 |
Family
ID=63371487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202100482UA SG11202100482UA (en) | 2018-08-09 | 2019-08-09 | Modified meningococcal fhbp polypeptides |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11708394B2 (en) |
| EP (2) | EP3607967A1 (en) |
| JP (2) | JP7271654B2 (en) |
| KR (1) | KR102677445B1 (en) |
| CN (1) | CN112566657B (en) |
| AU (1) | AU2019318120B2 (en) |
| BR (1) | BR112021000988A2 (en) |
| CA (1) | CA3108355A1 (en) |
| EA (1) | EA202190184A1 (en) |
| IL (1) | IL280189B1 (en) |
| MA (1) | MA53271A (en) |
| MX (1) | MX2021001610A (en) |
| SG (1) | SG11202100482UA (en) |
| WO (1) | WO2020030782A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2714248C2 (en) * | 2014-07-23 | 2020-02-13 | Чилдрен'З Хоспитал Энд Рисёрч Сентер Эт Окленд | Versions of factor n-binding protein and methods of use thereof |
| GB202013262D0 (en) | 2020-08-25 | 2020-10-07 | Glaxosmithkline Biologicals Sa | Vaccine Composition |
| CN114681601A (en) * | 2020-12-31 | 2022-07-01 | 基础治疗有限公司 | Neisseria meningitidis vaccines and uses thereof |
| TW202245836A (en) | 2021-02-19 | 2022-12-01 | 美商賽諾菲巴斯德公司 | Meningococcal b recombinant vaccine |
| GB202115077D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Assay |
| GB202115151D0 (en) | 2021-10-21 | 2021-12-08 | Glaxosmithkline Biologicals Sa | Methods |
| GB202208089D0 (en) * | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| GB202208093D0 (en) * | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| TW202423477A (en) | 2022-08-03 | 2024-06-16 | 美商賽諾菲巴斯德公司 | Adjuvanted immunogenic composition against neisseria meningitidis b |
| CN117264031B (en) * | 2023-11-03 | 2024-01-30 | 烟台派诺生物技术有限公司 | Group B neisseria meningitidis fHBP recombinant protein and application thereof |
| CN118240723B (en) * | 2024-05-29 | 2024-08-23 | 上海羽冠生物技术有限公司 | Method for producing bacterial outer membrane vesicles by fermentation |
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| DE2848965A1 (en) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | METHOD FOR PRODUCING MEMBRANE PROTEINS FROM NEISSERIA MENINGITIDIS AND VACCINE CONTAINING THEM |
| US4356170A (en) | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| US4459286A (en) | 1983-01-31 | 1984-07-10 | Merck & Co., Inc. | Coupled H. influenzae type B vaccine |
| US4663160A (en) | 1983-03-14 | 1987-05-05 | Miles Laboratories, Inc. | Vaccines for gram-negative bacteria |
| US4761283A (en) | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| US4882317A (en) | 1984-05-10 | 1989-11-21 | Merck & Co., Inc. | Covalently-modified bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers and methods of preparing such polysaccharides and conjugataes and of confirming covalency |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| US4808700A (en) | 1984-07-09 | 1989-02-28 | Praxis Biologics, Inc. | Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers |
| IT1187753B (en) | 1985-07-05 | 1987-12-23 | Sclavo Spa | GLYCOPROTEIC CONJUGATES WITH TRIVALENT IMMUNOGENIC ACTIVITY |
| NL8802046A (en) | 1988-08-18 | 1990-03-16 | Gen Electric | POLYMER MIXTURE WITH POLYESTER AND ALKANE SULFONATE, OBJECTS THEREFORE. |
| DE3841091A1 (en) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | SYNTHETIC ANTIGENS, METHOD FOR THEIR PRODUCTION AND THEIR USE |
| CA2006700A1 (en) | 1989-01-17 | 1990-07-17 | Antonello Pessi | Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines |
| WO1991001146A1 (en) | 1989-07-14 | 1991-02-07 | Praxis Biologics, Inc. | Cytokine and hormone carriers for conjugate vaccines |
| IT1237764B (en) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | SYNTHETIC PEPTIDES USEFUL AS UNIVERSAL CARRIERS FOR THE PREPARATION OF IMMUNOGENIC CONJUGATES AND THEIR USE FOR THE DEVELOPMENT OF SYNTHETIC VACCINES. |
| SE466259B (en) | 1990-05-31 | 1992-01-20 | Arne Forsgren | PROTEIN D - AN IGD BINDING PROTEIN FROM HAEMOPHILUS INFLUENZAE, AND THE USE OF THIS FOR ANALYSIS, VACCINES AND PURPOSE |
| IL98715A0 (en) | 1990-08-13 | 1992-07-15 | American Cyanamid Co | Filamentous hemaglutinin of bodetella pertussis as a carrier molecule for conjugate vaccines |
| IT1262896B (en) | 1992-03-06 | 1996-07-22 | CONJUGATE COMPOUNDS FORMED FROM HEAT SHOCK PROTEIN (HSP) AND OLIGO-POLY-SACCHARIDES, THEIR USE FOR THE PRODUCTION OF VACCINES. | |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| DE122009000058I1 (en) | 1993-09-22 | 2009-12-31 | Jackson H M Found Military Med | PROCESS FOR ACTIVATING SOLUBLE CARBOHYDRATE BY USING NEW CYANYLATION REAGENTS FOR PREPARING IMMUNOGENIC CONSTRUCTS |
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| GB9918319D0 (en) | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| WO2001034642A2 (en) | 1999-11-12 | 2001-05-17 | University Of Iowa Research Foundation | Control of neisserial membrane synthesis |
| DK1248647T3 (en) | 2000-01-17 | 2010-09-27 | Novartis Vaccines & Diagnostic | Outer membrane vesicle (OMV) vaccine comprising N. meningitidis serogroup B outer membrane proteins |
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| NO20002828D0 (en) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinaceous vaccine against Neisseria meningtidis serogroup and method of preparation thereof |
| ES2519440T3 (en) | 2000-07-27 | 2014-11-07 | Children's Hospital & Research Center At Oakland | Vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
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| DE60139563D1 (en) | 2000-10-27 | 2009-09-24 | Craig J Venter Inst Inc | NUCLEIC ACIDS AND PROTEINS FROM GROUPS A AND B-STREPTOKOKKEN |
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| KR20050039839A (en) | 2002-08-02 | 2005-04-29 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | Vaccine compositions comprising l2 and/or l3 immunotype lipooligosaccharides from lgtb- neisseria minigitidis |
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| PL2682126T3 (en) | 2005-01-27 | 2017-07-31 | Children's Hospital & Research Center At Oakland | GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis |
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| BR112012010531A2 (en) * | 2009-10-27 | 2019-09-24 | Novartis Ag | "fhbp meningococcal modification polypeptides" |
| EP2552942B1 (en) * | 2010-03-30 | 2017-12-27 | Children's Hospital & Research Center at Oakland | Factor h binding proteins (fhbp) with altered properties and methods of use thereof |
| MX2014002375A (en) | 2011-08-31 | 2014-09-15 | Children S Hospital & Res Ct Oakland | Engineered sequences to facilitate expression of antigens in neisseria and methods of use. |
| CN104114706A (en) | 2012-02-02 | 2014-10-22 | 诺华股份有限公司 | Promoters for increased protein expression in meningococcus |
| WO2015128480A1 (en) | 2014-02-28 | 2015-09-03 | Novartis Ag | Modified meningococcal fhbp polypeptides |
| WO2016008960A1 (en) * | 2014-07-17 | 2016-01-21 | Glaxosmithkline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| AR101225A1 (en) * | 2014-07-17 | 2016-11-30 | Glaxosmithkline Biologicals Sa | MENINGOCOCK VACCINES |
| RU2714248C2 (en) | 2014-07-23 | 2020-02-13 | Чилдрен'З Хоспитал Энд Рисёрч Сентер Эт Окленд | Versions of factor n-binding protein and methods of use thereof |
-
2018
- 2018-08-09 EP EP18188321.6A patent/EP3607967A1/en not_active Ceased
-
2019
- 2019-08-08 IL IL280189A patent/IL280189B1/en unknown
- 2019-08-09 US US17/265,610 patent/US11708394B2/en active Active
- 2019-08-09 WO PCT/EP2019/071410 patent/WO2020030782A1/en unknown
- 2019-08-09 MA MA053271A patent/MA53271A/en unknown
- 2019-08-09 CN CN201980053356.2A patent/CN112566657B/en active Active
- 2019-08-09 SG SG11202100482UA patent/SG11202100482UA/en unknown
- 2019-08-09 BR BR112021000988-4A patent/BR112021000988A2/en unknown
- 2019-08-09 EP EP19758346.1A patent/EP3833388A1/en active Pending
- 2019-08-09 JP JP2021506665A patent/JP7271654B2/en active Active
- 2019-08-09 EA EA202190184A patent/EA202190184A1/en unknown
- 2019-08-09 CA CA3108355A patent/CA3108355A1/en active Pending
- 2019-08-09 MX MX2021001610A patent/MX2021001610A/en unknown
- 2019-08-09 KR KR1020217006606A patent/KR102677445B1/en active Active
- 2019-08-09 AU AU2019318120A patent/AU2019318120B2/en active Active
-
2023
- 2023-01-27 JP JP2023010597A patent/JP2023061971A/en active Pending
- 2023-06-02 US US18/328,162 patent/US20240228551A9/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019318120A1 (en) | 2021-02-11 |
| CN112566657B (en) | 2025-03-14 |
| IL280189A (en) | 2021-03-01 |
| CN112566657A (en) | 2021-03-26 |
| WO2020030782A1 (en) | 2020-02-13 |
| US20240228551A9 (en) | 2024-07-11 |
| JP2023061971A (en) | 2023-05-02 |
| CA3108355A1 (en) | 2020-02-13 |
| IL280189B1 (en) | 2025-01-01 |
| EA202190184A1 (en) | 2021-05-14 |
| MX2021001610A (en) | 2021-04-19 |
| US20240132550A1 (en) | 2024-04-25 |
| EP3833388A1 (en) | 2021-06-16 |
| MA53271A (en) | 2021-11-17 |
| US20210277069A1 (en) | 2021-09-09 |
| AU2019318120B2 (en) | 2024-03-14 |
| EP3607967A1 (en) | 2020-02-12 |
| JP7271654B2 (en) | 2023-05-11 |
| KR102677445B1 (en) | 2024-06-20 |
| JP2021533748A (en) | 2021-12-09 |
| KR20210041594A (en) | 2021-04-15 |
| US11708394B2 (en) | 2023-07-25 |
| BR112021000988A2 (en) | 2021-04-27 |
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