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SG11201707282RA - Kv1.3 inhibitors and their medical application - Google Patents

Kv1.3 inhibitors and their medical application

Info

Publication number
SG11201707282RA
SG11201707282RA SG11201707282RA SG11201707282RA SG11201707282RA SG 11201707282R A SG11201707282R A SG 11201707282RA SG 11201707282R A SG11201707282R A SG 11201707282RA SG 11201707282R A SG11201707282R A SG 11201707282RA SG 11201707282R A SG11201707282R A SG 11201707282RA
Authority
SG
Singapore
Prior art keywords
inhibitors
medical application
medical
application
Prior art date
Application number
SG11201707282RA
Other languages
English (en)
Inventor
Stefan Tasler
Ilga Krimmelbein
Original Assignee
4Sc Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4Sc Ag filed Critical 4Sc Ag
Publication of SG11201707282RA publication Critical patent/SG11201707282RA/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/47—Quinolines; Isoquinolines
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
SG11201707282RA 2015-03-13 2016-03-14 Kv1.3 inhibitors and their medical application SG11201707282RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15159083 2015-03-13
PCT/EP2016/055441 WO2016146575A1 (en) 2015-03-13 2016-03-14 Kv1.3 inhibitors and their medical application

Publications (1)

Publication Number Publication Date
SG11201707282RA true SG11201707282RA (en) 2017-10-30

Family

ID=52684083

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201707282RA SG11201707282RA (en) 2015-03-13 2016-03-14 Kv1.3 inhibitors and their medical application

Country Status (29)

Country Link
US (2) US10399991B2 (pl)
EP (1) EP3268372B9 (pl)
JP (1) JP6506410B2 (pl)
KR (1) KR20170137055A (pl)
CN (1) CN107548396B (pl)
AU (1) AU2016232330B2 (pl)
BR (1) BR112017019386A2 (pl)
CA (1) CA2979501A1 (pl)
CY (1) CY1123797T1 (pl)
DK (1) DK3268372T3 (pl)
EA (1) EA036935B1 (pl)
ES (1) ES2818102T3 (pl)
HK (1) HK1243998A1 (pl)
HR (1) HRP20201425T1 (pl)
HU (1) HUE050606T2 (pl)
IL (1) IL254390B (pl)
LT (1) LT3268372T (pl)
MX (1) MX378039B (pl)
PH (1) PH12017501653B1 (pl)
PL (1) PL3268372T3 (pl)
PT (1) PT3268372T (pl)
RS (1) RS60800B1 (pl)
SG (1) SG11201707282RA (pl)
SI (1) SI3268372T1 (pl)
SM (1) SMT202000475T1 (pl)
TW (1) TWI698438B (pl)
UA (1) UA121494C2 (pl)
WO (1) WO2016146575A1 (pl)
ZA (1) ZA201705676B (pl)

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JP2022550641A (ja) * 2019-10-07 2022-12-02 ディー．イー．ショウ リサーチ，エルエルシー Ｋｖ１．３カリウムシェーカーチャネル遮断薬としてのアリール複素二環式化合物

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