|
US2976146A
(en)
|
1958-11-28 |
1961-03-21 |
Eastman Kodak Co |
Novel cyan-forming couplers
|
|
BE790440A
(es)
|
1971-10-23 |
1973-04-24 |
Bayer Ag |
|
|
JPS5752334B2
(es)
|
1974-02-05 |
1982-11-06 |
|
|
|
JPS538707B2
(es)
|
1974-02-05 |
1978-03-31 |
|
|
|
US3906953A
(en)
|
1974-05-23 |
1975-09-23 |
American Optical Corp |
Endoscopic surgical laser system
|
|
SU509578A1
(ru)
|
1974-09-19 |
1976-04-05 |
Стерлитамакский Химический Завод |
Способ получени пропилендиаминов
|
|
GB1502312A
(en)
|
1975-03-20 |
1978-03-01 |
Ici Ltd |
Quinolone derivatives
|
|
IE43079B1
(en)
|
1975-03-20 |
1980-12-17 |
Ici Ltd |
Quinolone derivatives
|
|
FR2311776A1
(fr)
|
1975-05-23 |
1976-12-17 |
Sogeras |
Diamino-2,4 bromo-5 chloro-6 pyrimidines et procede pour leur preparation
|
|
GB1570494A
(en)
|
1975-11-28 |
1980-07-02 |
Ici Ltd |
Thienopyrimidine derivatives and their use as pesticides
|
|
JPS5382783A
(en)
|
1976-12-29 |
1978-07-21 |
Yamanouchi Pharmaceut Co Ltd |
Novel pyridone derivs and process for their preparation
|
|
ZA782648B
(en)
|
1977-05-23 |
1979-06-27 |
Ici Australia Ltd |
The prevention,control or eradication of infestations of ixodid ticks
|
|
DE2750288A1
(de)
|
1977-11-10 |
1979-05-17 |
Thomae Gmbh Dr K |
Neue 9-(omega-heteroarylamino- alkylamino)-erythromycine, ihre salze, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
|
|
US4432979A
(en)
|
1981-10-26 |
1984-02-21 |
William H. Rorer, Inc. |
Pyridone compounds
|
|
FI824314L
(fi)
|
1981-12-16 |
1983-06-17 |
Sankyo Co |
Thienopyrimidin-derivater, deras framstaellning och deras medicinska anvaendning
|
|
US4358453A
(en)
|
1982-01-08 |
1982-11-09 |
Schering Corporation |
1,2,4-Triazolo[4,3-a]pyridines
|
|
US4520025A
(en)
|
1982-07-21 |
1985-05-28 |
William H. Rorer, Inc. |
Bicyclic nitrogen heterocyclic ethers and thioethers, and their pharmaceutical uses
|
|
JPS60159184A
(ja)
|
1984-01-27 |
1985-08-20 |
Agency Of Ind Science & Technol |
水電解用陽極
|
|
DE3406329A1
(de)
|
1984-02-22 |
1985-08-22 |
Merck Patent Gmbh, 6100 Darmstadt |
Pyridone
|
|
US4550166A
(en)
|
1984-05-21 |
1985-10-29 |
American Cyanamid Company |
(Pyridinyl)-1,2,4-triazolo[4,3-a]pyridines
|
|
US5175157A
(en)
|
1985-11-27 |
1992-12-29 |
Boehringer Ingelheim Gmbh |
Cyclic amine derivatives, pharmaceutical compositions containing these compounds and methods for preparing them
|
|
DE3717561A1
(de)
|
1987-05-25 |
1988-12-08 |
Thomae Gmbh Dr K |
Indol-, isochinolin- und benzazepinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
US4866074A
(en)
|
1987-05-08 |
1989-09-12 |
Rorer Pharmaceutical Corporation |
Naphtheridinone- and pyridooxazinone-pyridone compounds, cardiotonic compositions including same, and their uses
|
|
EP0308020A3
(en)
|
1987-09-18 |
1990-12-05 |
Merck & Co. Inc. |
5-(aryl and heteroaryl)-6-(aryl and heteroaryl)-1,2-dihydro-2-oxo 3-pyridinecarboxylic acids and derivatives thereof
|
|
US5260293A
(en)
|
1988-01-30 |
1993-11-09 |
Merck Sharp & Dohme Limited |
Pyrazines, pyrimidines and pyridazines useful in the treatment of senile dementia
|
|
GB8804448D0
(en)
|
1988-02-25 |
1988-03-23 |
Smithkline Beckman Intercredit |
Compounds
|
|
JP2614081B2
(ja)
|
1988-05-27 |
1997-05-28 |
大塚化学株式会社 |
光学活性β−ラクタム誘導体の製造法
|
|
JPH02124871A
(ja)
|
1988-07-27 |
1990-05-14 |
Dainippon Pharmaceut Co Ltd |
１位が置換された複素環式カルボン酸アミド誘導体
|
|
DE68923527D1
(de)
|
1988-10-20 |
1995-08-24 |
Sandoz Ag |
Faserreaktive Azofarbstoffe.
|
|
US5032602A
(en)
|
1988-12-14 |
1991-07-16 |
Bayer Aktiengesellschaft |
Inhibiting HMG-CoA reductase with novel substituted 2-pyridones and pyrid-2-thiones
|
|
HU206337B
(en)
|
1988-12-29 |
1992-10-28 |
Mitsui Petrochemical Ind |
Process for producing pyrimidine derivatives and pharmaceutical compositions
|
|
JPH02277044A
(ja)
|
1989-04-19 |
1990-11-13 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料
|
|
US5236917A
(en)
|
1989-05-04 |
1993-08-17 |
Sterling Winthrop Inc. |
Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
|
|
US5280026A
(en)
|
1989-05-30 |
1994-01-18 |
Smithkline Beecham Intercredit B.V. |
Thienopyrimidines
|
|
AU622330B2
(en)
|
1989-06-23 |
1992-04-02 |
Takeda Chemical Industries Ltd. |
Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
|
|
US4978663A
(en)
|
1989-08-16 |
1990-12-18 |
Hoechst-Roussel Pharmaceuticals Inc. |
5-(1-aminocyclohexyl)-2(1H)-pyridinone compounds which have pharmaceutical utility
|
|
GB8926560D0
(en)
|
1989-11-24 |
1990-01-17 |
Zambeletti Spa L |
Pharmaceuticals
|
|
IL96432A0
(en)
|
1989-11-30 |
1991-08-16 |
Schering Ag |
Pesticidal compositions containing pyridine derivatives and novel pyridine derivatives
|
|
DE3940480A1
(de)
|
1989-12-07 |
1991-06-13 |
Bayer Ag |
Chromogene enaminverbindungen, ihre herstellung und verwendung als farbbildner
|
|
AU6979091A
(en)
|
1989-12-22 |
1991-07-24 |
Upjohn Company, The |
Pyridinones useful as antiatherosclerotic agents
|
|
FR2657610A1
(fr)
|
1990-01-29 |
1991-08-02 |
Rhone Poulenc Agrochimie |
Triazolopyridines herbicides.
|
|
GB9104238D0
(en)
|
1990-03-16 |
1991-04-17 |
Ici Pharma |
3-tetrazolylthiomethyl cephalosporin antibiotics
|
|
DE4008726A1
(de)
|
1990-03-19 |
1991-09-26 |
Basf Ag |
Thieno(2,3-d)pyrimidinderivate
|
|
CA2039411A1
(en)
|
1990-03-30 |
1991-10-01 |
Ronnie Gerald Edie |
Thienopyrimidine derivatives
|
|
RU1796625C
(ru)
|
1990-06-27 |
1993-02-23 |
Киевский Государственный Университет Им.Т.Г.Шевченко |
3-Амино-7-нитро-4(2,3,4-триметоксифенил)-2-фенил-1(2Н)изохинолон, обладающий аналептическим действием
|
|
DE69131268T2
(de)
|
1990-09-21 |
1999-12-30 |
Rohm And Haas Co., Philadelphia |
Dihydropyridazinone und Pyridazinone als Fungizide
|
|
KR920008026A
(ko)
|
1990-10-24 |
1992-05-27 |
오노 화아마슈티칼 캄파니 리미팃드 |
이소퀴놀리논 유도체 또는 이의 무독성 산부가염 또는 이의 수화물, 이의 제조방법 및 이를 포함하는 약제 조성물
|
|
AU1532492A
(en)
|
1991-04-18 |
1992-11-17 |
Dr. Lo Zambeletti S.P.A. |
Use of heterocyclic compounds for the treatment of inflammatory pain
|
|
DE4122240A1
(de)
|
1991-07-05 |
1993-01-07 |
Boehringer Mannheim Gmbh |
Dibenz(b,e)azepinderivate und diese enthaltende arzneimittel
|
|
DE4129340A1
(de)
|
1991-09-04 |
1993-03-11 |
Merck Patent Gmbh |
1,2-dihydro-2-oxopyridine
|
|
US5332750A
(en)
|
1991-09-04 |
1994-07-26 |
Merck Patent Gesellschaft Mit Beschrankter Haftung |
1,2-dihydro-2-oxopyridines
|
|
DE4131924A1
(de)
|
1991-09-25 |
1993-07-08 |
Hoechst Ag |
Substituierte 4-alkoxypyrimidine, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel
|
|
US5204198A
(en)
|
1991-10-28 |
1993-04-20 |
Eastman Kodak Company |
Photoelectrographic elements utilizing nonionic sulfonic acid photogenerators
|
|
US5416099A
(en)
|
1991-10-29 |
1995-05-16 |
Merck & Co., Inc. |
Fibrinogen receptor antagonists
|
|
DE4221583A1
(de)
|
1991-11-12 |
1993-05-13 |
Bayer Ag |
Substituierte biphenylpyridone
|
|
JP2878531B2
(ja)
|
1991-12-16 |
1999-04-05 |
富士写真フイルム株式会社 |
ハロゲン化銀写真感光材料
|
|
US5378720A
(en)
|
1991-12-19 |
1995-01-03 |
Sterling Winthrop Inc. |
Saccharin derivative proteolytic enzyme inhibitors
|
|
AU668694B2
(en)
|
1991-12-19 |
1996-05-16 |
Sanofi-Synthelabo |
Saccharin derivative proteolytic enzyme inhibitors
|
|
TW219935B
(es)
|
1991-12-25 |
1994-02-01 |
Mitsubishi Chemicals Co Ltd |
|
|
GB9200293D0
(en)
|
1992-01-08 |
1992-02-26 |
Wyeth John & Brother Ltd |
Piperazine derivatives
|
|
GB9201694D0
(en)
|
1992-01-27 |
1992-03-11 |
Smithkline Beecham Intercredit |
Compounds
|
|
JPH05204071A
(ja)
|
1992-01-29 |
1993-08-13 |
Konica Corp |
ハロゲン化銀写真感光材料
|
|
JP3042156B2
(ja)
|
1992-02-20 |
2000-05-15 |
田辺製薬株式会社 |
ナフタレン誘導体、その製法及びその合成中間体
|
|
DE4206045A1
(de)
|
1992-02-27 |
1993-09-02 |
Bayer Ag |
Sulfonylbenzyl substituierte pyridone
|
|
US5922773A
(en)
|
1992-12-04 |
1999-07-13 |
The Children's Medical Center Corp. |
Glaucoma treatment
|
|
AU660132B2
(en)
|
1992-12-21 |
1995-06-08 |
Bayer Aktiengesellschaft |
Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridine
|
|
JPH06211798A
(ja)
|
1993-01-19 |
1994-08-02 |
Tosoh Corp |
テトラヒドロイソキノリノン誘導体及びその製造方法
|
|
JPH06211797A
(ja)
|
1993-01-19 |
1994-08-02 |
Tosoh Corp |
テトラヒドロイソキノリン誘導体、その製法及び抗真菌剤
|
|
SE9300657D0
(sv)
|
1993-02-26 |
1993-02-26 |
Astra Ab |
New compounds
|
|
US5814645A
(en)
|
1993-03-24 |
1998-09-29 |
Bayer Aktiengesellschaft |
Arylor hetaryl substituted nitrogen heterocycles and their use as pesticides
|
|
DE4316077A1
(de)
|
1993-05-13 |
1994-11-17 |
Bayer Ag |
Substituierte Mono- und Bihydridylmethylpyridone
|
|
EP0702671A4
(en)
|
1993-06-09 |
1996-06-19 |
Smithkline Beecham Corp |
BICYCLIC FIBRINOGEN ANTAGONISTS
|
|
JP3333271B2
(ja)
|
1993-06-17 |
2002-10-15 |
大日本印刷株式会社 |
自動丁合装置
|
|
JPH07101861A
(ja)
|
1993-08-10 |
1995-04-18 |
Tanabe Seiyaku Co Ltd |
抗喘息薬
|
|
DE4326758A1
(de)
|
1993-08-10 |
1995-02-16 |
Basf Ag |
[1,3,4]Triazolo[1,5-a]pyridine
|
|
US5824682A
(en)
|
1993-08-18 |
1998-10-20 |
Janssen Pharmaceutica, N.V. |
Vasoconstrictive dihydrobenzopyran derivatives
|
|
PL179008B1
(pl)
|
1993-08-19 |
2000-07-31 |
Janssen Pharmaceutica Nv |
Nowy zwiazek, podstawiona aryloksyalkilodwuamina o dzialaniu naczyniozwezajacym, kompozycja farmaceutycznai sposób wytwarzania podstawionej aryloksyalkilodwuaminy. PL PL
|
|
AU7467294A
(en)
|
1993-08-20 |
1995-03-21 |
Banyu Pharmaceutical Co., Ltd. |
Tyrosine kinase inhibitor
|
|
JP3701984B2
(ja)
|
1993-08-31 |
2005-10-05 |
サントリー株式会社 |
ラベル化シクロプロパン誘導体およびその製造方法
|
|
US5424435A
(en)
|
1993-10-18 |
1995-06-13 |
Olin Corporation |
1-hydroxy-6-substituted-2-pyridones
|
|
US5500420A
(en)
|
1993-12-20 |
1996-03-19 |
Cornell Research Foundation, Inc. |
Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia
|
|
US5654307A
(en)
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
|
DE69522676T2
(de)
|
1994-03-10 |
2002-04-18 |
Fujisawa Pharmaceutical Co., Ltd. |
Naphtalen-derivate als prostaglandin i2 agonisten
|
|
ES2079323B1
(es)
|
1994-06-21 |
1996-10-16 |
Vita Invest Sa |
Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes.
|
|
GB9416554D0
(en)
|
1994-08-19 |
1994-10-12 |
Ciba Geigy Ag |
Glutamate receptor
|
|
JPH10504569A
(ja)
|
1994-08-24 |
1998-05-06 |
イーライ・リリー・アンド・カンパニー |
向代謝性グルタメート受容体拮抗剤としてのピロリジニルジカルボン酸誘導体
|
|
US5473077A
(en)
|
1994-11-14 |
1995-12-05 |
Eli Lilly And Company |
Pyrrolidinyl di-carboxylic acid derivatives as metabotropic glutamate receptor agonists
|
|
US6017697A
(en)
|
1994-11-14 |
2000-01-25 |
Eli Lilly And Company |
Excitatory amino acid receptor protein and related nucleic acid compounds
|
|
US5512576A
(en)
|
1994-12-02 |
1996-04-30 |
Sterling Winthrop Inc. |
2-substituted 1,2,5,-thiadiazolidin-3-one 1,1-dioxides and compositions and method of use thereof
|
|
US5789426A
(en)
|
1995-01-20 |
1998-08-04 |
Cornell Research Foundation, Inc. |
Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
|
|
US5869486A
(en)
|
1995-02-24 |
1999-02-09 |
Ono Pharmaceutical Co., Ltd. |
Fused pyrimidines and pyriazines as pharmaceutical compounds
|
|
DE19507522C2
(de)
|
1995-03-03 |
2003-05-28 |
Basf Ag |
Verfahren zur Herstellung von 3,4-Dihydroisochinolinverbindungen und 3,4-Dihydroisochinolinium-Salzen
|
|
US5869428A
(en)
|
1995-03-13 |
1999-02-09 |
Ishihara Sangyo Kaisha Ltd. |
Pyridonesulfonylurea compounds, process for their production and herbicides containing them
|
|
DE19510965A1
(de)
|
1995-03-24 |
1996-09-26 |
Asta Medica Ag |
Neue Pyrido/3,2-e/pyrazinone mit antiasthmatischer Wirksamkeit und Verfahren zu deren Herstellung
|
|
WO1996033974A1
(fr)
|
1995-04-27 |
1996-10-31 |
The Green Cross Corporation |
Composes heterocycliques amides et leur utilisation medicinale
|
|
JPH08325248A
(ja)
|
1995-05-26 |
1996-12-10 |
Chugoku Kayaku Kk |
テトラゾール類の新規な合成試薬及びそれを用いたテトラゾール類の製造方法
|
|
US5849587A
(en)
|
1995-06-09 |
1998-12-15 |
Cornell Research Foundation, Inc. |
Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
|
|
EP0756200B1
(en)
|
1995-07-26 |
1999-11-10 |
Konica Corporation |
Silver halide color photographic light-sensitive material
|
|
US5659033A
(en)
|
1995-09-13 |
1997-08-19 |
Neurogen Corporation |
N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands
|
|
ATE187172T1
(de)
|
1995-09-15 |
1999-12-15 |
Sanofi Synthelabo |
Chinolin-2-on derivate als serotonin antagonisten
|
|
JPH1045750A
(ja)
|
1995-09-20 |
1998-02-17 |
Takeda Chem Ind Ltd |
アゾール化合物、その製造方法及び用途
|
|
US6130217A
(en)
|
1995-09-20 |
2000-10-10 |
Pfizer Inc |
Compounds enhancing antitumor activity of other cytotoxic agents
|
|
AR004010A1
(es)
|
1995-10-11 |
1998-09-30 |
Glaxo Group Ltd |
Compuestos heterociclicos
|
|
AP1108A
(en)
|
1995-12-08 |
2002-10-02 |
Janssen Pharmaceutica Nv |
Farnesyl protein transferase inhibiting (imidazol-5-Y1) Methyl-2-Quinoline derivatives.
|
|
GB9602166D0
(en)
|
1996-02-02 |
1996-04-03 |
Zeneca Ltd |
Aminoheterocyclic derivatives
|
|
EP0880501A1
(en)
|
1996-02-02 |
1998-12-02 |
Zeneca Limited |
Heterocyclic compounds useful as pharmaceutical agents
|
|
GB9602294D0
(en)
|
1996-02-05 |
1996-04-03 |
Zeneca Ltd |
Heterocyclic compounds
|
|
US6084084A
(en)
|
1996-02-21 |
2000-07-04 |
Nps Pharmaceuticals, Inc. |
Human metabotropic glutamate receptor
|
|
US5710274A
(en)
|
1996-02-28 |
1998-01-20 |
Neurogen Corporation |
N-aminoalkyldibenzofurancarboxamides; new dopamine receptor subtype specific ligands
|
|
US5756518A
(en)
|
1996-04-02 |
1998-05-26 |
Kowa Co., Ltd. |
Phenylene derivatives
|
|
JPH1029979A
(ja)
|
1996-04-12 |
1998-02-03 |
Ajinomoto Co Inc |
新規ピリジン誘導体
|
|
WO1997046532A1
(en)
|
1996-06-03 |
1997-12-11 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
2-benzyl-4-sulfonyl-4h-isoquinolin-1,3-diones and their use as anti-inflammatory agents
|
|
WO1998006724A1
(fr)
|
1996-08-09 |
1998-02-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Agonistes du recepteur du glutamate metabotropique
|
|
DE19632423A1
(de)
|
1996-08-12 |
1998-02-19 |
Merck Patent Gmbh |
Thienopyrimidine
|
|
SK18499A3
(en)
|
1996-08-14 |
1999-07-12 |
Zeneca Ltd |
Substituted pyrimidine derivatives and their pharmaceutical use
|
|
DE69710594T2
(de)
|
1996-09-16 |
2002-08-29 |
Du Pont Pharmaceuticals Co., Wilmington |
Eine resorbierbare röntgenopake markierung enthaltendes chirurgisches implantat und verfahren zum verriegeln desselben in einem körper
|
|
DE19638486A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
|
DE19638484A1
(de)
|
1996-09-20 |
1998-03-26 |
Basf Ag |
Hetaroylderivate
|
|
DE19644228A1
(de)
|
1996-10-24 |
1998-04-30 |
Merck Patent Gmbh |
Thienopyrimidine
|
|
US6284794B1
(en)
|
1996-11-05 |
2001-09-04 |
Head Explorer Aps |
Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
|
|
NZ335992A
(en)
|
1996-12-05 |
2001-09-28 |
Amgen Inc |
Substituted pyrimidinone and pyridone compounds and methods of use
|
|
DE19653647A1
(de)
|
1996-12-20 |
1998-06-25 |
Hoechst Ag |
Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
|
|
US6482821B2
(en)
|
1996-12-20 |
2002-11-19 |
Hoechst Aktiengellschaft |
Vitronectin receptor antagonists, their preparation and their use
|
|
NZ336676A
(en)
|
1997-01-24 |
2000-01-28 |
Norsk Hydro As |
Gemcitabine esters or amides useful as anti-cancer and anti-viral agents
|
|
US5855654A
(en)
|
1997-01-30 |
1999-01-05 |
Rohm And Haas Company |
Pyridazinones as marine antifouling agents
|
|
FR2759366B1
(fr)
|
1997-02-11 |
1999-04-16 |
Centre Nat Rech Scient |
Composes constituant notamment des effecteurs de recepteurs du systeme nerveux central sensibles aux amino acides neuroexcitateurs, leur preparation et leurs applications biologiques
|
|
US6262068B1
(en)
|
1997-02-21 |
2001-07-17 |
Bristol-Myers Squibb Company |
Lactam derivatives as antiarrhythmic agents
|
|
AU6230098A
(en)
|
1997-02-27 |
1998-09-18 |
Tanabe Seiyaku Co., Ltd. |
Isoquinolinone derivatives, process for preparing the same, and their use as phosphodiesterase inhibitors
|
|
ES2131463B1
(es)
|
1997-04-08 |
2000-03-01 |
Lilly Sa |
Derivados de ciclopropilglicina con propiedades farmaceuticas.
|
|
GB9708945D0
(en)
|
1997-05-01 |
1997-06-25 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
DE19728996A1
(de)
|
1997-07-07 |
1999-01-14 |
Basf Ag |
Triazolverbindungen und deren Verwendung
|
|
AU743899B2
(en)
|
1997-07-18 |
2002-02-07 |
Georgetown University |
Bicyclic metabotropic glutamate receptor ligands
|
|
EP0891978B1
(en)
|
1997-07-18 |
2002-03-20 |
F. Hoffmann-La Roche Ag |
5H-Thiazolo (3,2-a) pyrimidine derivatives
|
|
PT1035848E
(pt)
|
1997-07-31 |
2003-09-30 |
Celgene Corp |
Acidos alcano-hidroxamicos substituidos e metodo de reducao dos niveis de tnf alfa
|
|
ATE262331T1
(de)
|
1997-08-14 |
2004-04-15 |
Hoffmann La Roche |
Heterocyclische vinylether zur behandlung neurologischer krankheiten
|
|
US6358975B1
(en)
|
1997-08-15 |
2002-03-19 |
Johns Hopkins University |
Method of using selective parp inhibitors to prevent or treat neurotoxicity
|
|
US6121278A
(en)
|
1997-09-03 |
2000-09-19 |
Guilford Pharmaceuticals, Inc. |
Di-n-heterocyclic compounds, methods, and compositions for inhibiting parp activity
|
|
US20020022636A1
(en)
|
1997-09-03 |
2002-02-21 |
Jia-He Li |
Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity
|
|
US6635642B1
(en)
|
1997-09-03 |
2003-10-21 |
Guilford Pharmaceuticals Inc. |
PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same
|
|
US20020028813A1
(en)
|
1997-09-03 |
2002-03-07 |
Paul F. Jackson |
Thioalkyl compounds, methods, and compositions for inhibiting parp activity
|
|
WO1999011622A1
(en)
|
1997-09-03 |
1999-03-11 |
Guilford Pharmaceuticals Inc. |
Amino-substituted compounds, methods, and compositions for inhibiting parp activity
|
|
US6197785B1
(en)
|
1997-09-03 |
2001-03-06 |
Guilford Pharmaceuticals Inc. |
Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity
|
|
AU9740998A
(en)
|
1997-09-08 |
1999-03-29 |
F. Hoffmann-La Roche Ag |
Piperidine derivatives against malaria
|
|
DE69815008T2
(de)
|
1997-09-19 |
2004-04-01 |
Ssp Co., Ltd. |
Alfa-substituierte Phenylpropionsäurederivate und diese enthaltende Arzneimittel
|
|
US6162804A
(en)
|
1997-09-26 |
2000-12-19 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
WO1999016755A1
(en)
|
1997-09-26 |
1999-04-08 |
Merck & Co., Inc. |
Novel angiogenesis inhibitors
|
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
|
AU9781098A
(en)
|
1997-10-02 |
1999-04-27 |
Merck & Co., Inc. |
Inhibitors of prenyl-protein transferase
|
|
IL135588A0
(en)
|
1997-10-14 |
2001-05-20 |
Welfide Corp |
Piperazine derivatives and pharmaceutical compositions containing the same
|
|
WO1999021992A2
(en)
|
1997-10-23 |
1999-05-06 |
Ganimed Pharmaceuticals Gmbh |
Nucleic acid molecules encoding a glutamate receptor
|
|
WO1999031062A1
(fr)
|
1997-12-17 |
1999-06-24 |
Shionogi & Co., Ltd. |
Nouveaux composes de pyridine
|
|
DE69839221T2
(de)
|
1997-12-18 |
2009-04-30 |
Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield |
Pyridone als hemmer der sh2-domäne der src-familie
|
|
US6013672A
(en)
|
1997-12-18 |
2000-01-11 |
Uab Research Foundation |
Agonists of metabotropic glutamate receptors and uses thereof
|
|
SI1042293T1
(sl)
|
1997-12-19 |
2008-08-31 |
Amgen Inc |
Substituirane piridinske in piridazinske spojine in njihova farmacevtska uporaba
|
|
FR2772763B1
(fr)
|
1997-12-24 |
2004-01-23 |
Sod Conseils Rech Applic |
Nouveaux analogues tetracycliques de camptothecines, leurs procedes de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
|
|
IT1298155B1
(it)
|
1998-01-19 |
1999-12-20 |
Moreno Paolini |
Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della
|
|
US6664250B2
(en)
|
1998-01-20 |
2003-12-16 |
Bristol-Myers Squibb Co. |
Lactam derivatives as antiarrhythmic agents
|
|
CN1182105C
(zh)
|
1998-01-28 |
2004-12-29 |
大正制药株式会社 |
含氟氨基酸衍生物
|
|
EP1056742B1
(en)
|
1998-02-17 |
2003-07-23 |
Tularik, Inc. |
Anti-viral pyrimidine derivatives
|
|
DE69919142T2
(de)
|
1998-03-17 |
2005-01-20 |
Pfizer Products Inc., Groton |
Bicyclo [2.2.1] heptane und verwandte verbindungen
|
|
ID27165A
(id)
|
1998-04-08 |
2001-03-08 |
Novaris Ag |
Herbisida-herbisida n-piridonil
|
|
AU3170099A
(en)
|
1998-04-16 |
1999-11-08 |
Yamanouchi Pharmaceutical Co., Ltd. |
Remedies for obesity
|
|
EP0955301A3
(en)
|
1998-04-27 |
2001-04-18 |
Pfizer Products Inc. |
7-aza-bicyclo[2.2.1]-heptane derivatives, their preparation and use according to their affinity for neuronal nicotinic acetylcholine receptors
|
|
DE19822198C2
(de)
|
1998-05-16 |
2003-02-13 |
Wella Ag |
Oxonolfarbstoffe enthaltende Mittel und Verfahren zur Erzeugung von semipermanenten Färbungen auf Haaren
|
|
US6288054B1
(en)
|
1998-06-02 |
2001-09-11 |
Merck & Co., Inc. |
Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
|
|
SK18542000A3
(sk)
|
1998-06-04 |
2001-12-03 |
Abbott Laboratories |
Protizápalové zlúčeniny inhibujúce bunkovú adhéziu
|
|
DE19826671A1
(de)
|
1998-06-16 |
1999-12-23 |
Hoechst Schering Agrevo Gmbh |
1,3-Oxazolin- und 1,3-Thiazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
|
|
FR2781218B1
(fr)
|
1998-07-15 |
2001-09-07 |
Lafon Labor |
Compositions pharmaceutiques comprenant des 2-quinolones
|
|
JP2000072751A
(ja)
|
1998-08-26 |
2000-03-07 |
Tanabe Seiyaku Co Ltd |
イソキノリノン誘導体
|
|
EP1110943B1
(en)
|
1998-08-31 |
2004-06-16 |
Taisho Pharmaceutical Co. Ltd. |
6-fluorobicyclo 3. 1.0]hexane derivatives
|
|
JP2002523459A
(ja)
|
1998-08-31 |
2002-07-30 |
メルク エンド カムパニー インコーポレーテッド |
新規血管形成阻害剤
|
|
JP2000072731A
(ja)
|
1998-08-31 |
2000-03-07 |
Taisho Pharmaceut Co Ltd |
４−置換−２−アミノビシクロ［３．１．０］ヘキサン−２，６−ジカルボン酸誘導体及び製薬用組成物
|
|
CH694053A5
(de)
|
1998-09-03 |
2004-06-30 |
Hoffmann La Roche |
Verfahren zur Herstellung von 2-Amino-bicyclo[3.1.0]hexan-2,6-dicarbonsäure-Derivaten.
|
|
US6284759B1
(en)
|
1998-09-30 |
2001-09-04 |
Neurogen Corporation |
2-piperazinoalkylaminobenzo-azole derivatives: dopamine receptor subtype specific ligands
|
|
SE9803518D0
(sv)
|
1998-10-15 |
1998-10-15 |
Astra Pharma Prod |
Novel compounds
|
|
PE20001236A1
(es)
|
1998-11-13 |
2000-11-10 |
Lilly Co Eli |
Moduladores del receptor de aminoacidos excitadores
|
|
US6133271A
(en)
|
1998-11-19 |
2000-10-17 |
Cell Pathways, Inc. |
Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
|
|
US5948911A
(en)
|
1998-11-20 |
1999-09-07 |
Cell Pathways, Inc. |
Method for inhibiting neoplastic cells and related conditions by exposure to thienopyrimidine derivatives
|
|
EP1006112A1
(en)
|
1998-12-01 |
2000-06-07 |
Cerebrus Pharmaceuticals Limited |
3-Hydroxy-2(1H)-pyridinone or 3-hydroxy-4(1H)-pyridinone derivatives useful as reactive oxygen species (ROS) scavengers
|
|
WO2000034244A1
(en)
|
1998-12-04 |
2000-06-15 |
Bristol-Myers Squibb Company |
3-substituted-4-arylquinolin-2-one derivatives as potassium channel modulators
|
|
US6245759B1
(en)
|
1999-03-11 |
2001-06-12 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
TW564247B
(en)
|
1999-04-08 |
2003-12-01 |
Akzo Nobel Nv |
Bicyclic heteraromatic compound
|
|
GB9908175D0
(en)
|
1999-04-09 |
1999-06-02 |
Lilly Co Eli |
Method of treating neurological disorders
|
|
US6723711B2
(en)
|
1999-05-07 |
2004-04-20 |
Texas Biotechnology Corporation |
Propanoic acid derivatives that inhibit the binding of integrins to their receptors
|
|
US6972296B2
(en)
|
1999-05-07 |
2005-12-06 |
Encysive Pharmaceuticals Inc. |
Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
|
|
EP1183238A1
(en)
|
1999-05-17 |
2002-03-06 |
Eli Lilly And Company |
Metabotropic glutamate receptor antagonists
|
|
EP1196397B1
(en)
|
1999-06-02 |
2005-08-17 |
Nps Pharmaceuticals, Inc. |
Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
|
|
CA2390948A1
(en)
|
1999-06-03 |
2000-12-14 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
|
EP1189873A1
(en)
|
1999-06-03 |
2002-03-27 |
Lilly, S.A. |
Excitatory amino acid receptor modulators
|
|
JP4783967B2
(ja)
|
1999-07-21 |
2011-09-28 |
大正製薬株式会社 |
含フッ素アミノ酸誘導体を有効成分とする医薬
|
|
MXPA02001340A
(es)
|
1999-08-05 |
2004-07-16 |
Prescient Neuropharma Inc |
Compuestos novedosos 1,4-benzodiazepina y derivados de los mismos.
|
|
US6660753B2
(en)
|
1999-08-19 |
2003-12-09 |
Nps Pharmaceuticals, Inc. |
Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
|
|
US7040838B2
(en)
|
1999-08-27 |
2006-05-09 |
Kristar Enterprises, Inc. |
High capacity catch basin filtration system with adjustable deflector ring
|
|
SI1224175T1
(en)
|
1999-10-15 |
2004-08-31 |
F. Hoffmann-La Roche Ag |
Benzodiazepine derivatives as metabotropic glutamate receptor antagonists
|
|
CZ20021653A3
(cs)
|
1999-10-15 |
2002-08-14 |
F. Hoffmann-La Roche Ag |
Nové deriváty benzodiazepinu
|
|
NZ518001A
(en)
|
1999-10-19 |
2004-05-28 |
Merck & Co Inc |
Tyrosine kinase inhibitors
|
|
SV2002000205A
(es)
|
1999-11-01 |
2002-06-07 |
Lilly Co Eli |
Compuestos farmaceuticos ref. x-01095
|
|
GB2355982A
(en)
|
1999-11-03 |
2001-05-09 |
Lilly Co Eli |
Heterocyclic amino acids
|
|
AU2220801A
(en)
|
1999-12-22 |
2001-07-03 |
Kyorin Pharmaceutical Co. Ltd. |
Tricyclic compounds and addition salts thereof
|
|
MXPA02007036A
(es)
|
2000-01-20 |
2002-12-13 |
Eisai Co Ltd |
Compuesto de piperidina novedoso y composicion farmaceutica del mismo.
|
|
GB0002100D0
(en)
|
2000-01-28 |
2000-03-22 |
Novartis Ag |
Organic compounds
|
|
AU2001234420A1
(en)
|
2000-02-03 |
2001-08-14 |
Eli Lilly And Company |
Potentiators of glutamate receptors
|
|
IL150912A0
(en)
|
2000-02-25 |
2003-02-12 |
Hoffmann La Roche |
Adenosine receptor modulators
|
|
DE10012373A1
(de)
|
2000-03-14 |
2001-09-20 |
Dresden Arzneimittel |
Verwendung von Pyrido[3,2-e]-pyrazinonen als Inhibitoren der Phosphodiesterase 5 zur Therapie von erektiler Dysfunktion
|
|
GB0007108D0
(en)
|
2000-03-23 |
2000-05-17 |
Novartis Ag |
Organic compounds
|
|
AU2001249399A1
(en)
|
2000-03-24 |
2001-10-08 |
Cor Therapeutics, Inc. |
Isoquinolone inhibitors of factor xa
|
|
JP2001270871A
(ja)
|
2000-03-24 |
2001-10-02 |
Sumitomo Chem Co Ltd |
オキシラン化合物の製造方法
|
|
GB0007193D0
(en)
|
2000-03-25 |
2000-05-17 |
Univ Manchester |
Treatment of movrmrnt disorders
|
|
US6403588B1
(en)
|
2000-04-27 |
2002-06-11 |
Yamanouchi Pharmaceutical Co., Ltd. |
Imidazopyridine derivatives
|
|
ES2244613T3
(es)
|
2000-04-27 |
2005-12-16 |
Astellas Pharma Inc. |
Derivados de imidazopiridina.
|
|
CN1209336C
(zh)
|
2000-04-28 |
2005-07-06 |
日本农药株式会社 |
生产2－卤代苯甲酸的方法
|
|
EP1288199A4
(en)
|
2000-04-28 |
2005-10-12 |
Shionogi & Co |
INHIBITORS OF MMP-12
|
|
US20020009713A1
(en)
|
2000-05-11 |
2002-01-24 |
Miller Freda D. |
Methods for identifying modulators of neuronal growth
|
|
AU2000258650A1
(en)
|
2000-05-11 |
2001-11-20 |
Eli Lilly And Co |
2-piperidone compounds for the treatment of cancer
|
|
AU2001256039A1
(en)
|
2000-05-11 |
2001-11-20 |
Kenneth Curry |
Novel spiro(2.4)heptane amino carboxy compounds and derivatives thereof
|
|
US7081481B2
(en)
|
2000-05-31 |
2006-07-25 |
Eli Lilly And Company |
Excitatory amino acid receptor modulators
|
|
CA2412172C
(en)
|
2000-06-12 |
2012-07-24 |
Eisai Co., Ltd. |
1,2-dihydropyridine compounds, manufacturing method thereof and use thereof
|
|
JP2002003401A
(ja)
|
2000-06-27 |
2002-01-09 |
Japan Science & Technology Corp |
脳由来神経栄養因子誘導剤
|
|
JP2002012533A
(ja)
|
2000-06-27 |
2002-01-15 |
Kao Corp |
染毛剤組成物
|
|
EP1297138A2
(en)
|
2000-06-27 |
2003-04-02 |
Centre National De La Recherche Scientifique (Cnrs) |
Mammal 2p domain mechano-sensitive k+ channel, cloning and applications thereof
|
|
US6770676B2
(en)
|
2000-06-28 |
2004-08-03 |
Taisho Pharmaceutical Co., Ltd. |
Dicarboxylic acid derivatives
|
|
DE10031390A1
(de)
|
2000-07-03 |
2002-01-17 |
Knoll Ag |
Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
|
|
US20020041880A1
(en)
|
2000-07-05 |
2002-04-11 |
Defeo-Jones Deborah |
Method of treating cancer
|
|
JP2002069057A
(ja)
|
2000-07-07 |
2002-03-08 |
Kyowa Hakko Kogyo Co Ltd |
ピペリジン誘導体
|
|
JP2002040252A
(ja)
|
2000-07-27 |
2002-02-06 |
Shiseido Co Ltd |
コレステリック液晶層を含む光学シート、それを用いた情報記録体、情報記録方法並びに情報判別方法
|
|
DE10038019A1
(de)
|
2000-08-04 |
2002-02-14 |
Bayer Ag |
Substituierte Triazolopyrid(az)ine
|
|
KR100804111B1
(ko)
|
2000-08-11 |
2008-02-18 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
2-아미노피리딘 화합물 및 그의 의약 용도
|
|
EP1849782A1
(en)
|
2000-09-11 |
2007-10-31 |
Novartis Vaccines and Diagnostics, Inc. |
Quinolinone derivatives as tyrosine kinase inhibitors
|
|
US6599940B2
(en)
|
2000-09-13 |
2003-07-29 |
Georgetown University |
Synthesis of 2-hydroxymethylglutamic acid and congeners thereof
|
|
JP2002105085A
(ja)
|
2000-09-28 |
2002-04-10 |
Yamanouchi Pharmaceut Co Ltd |
新規イミダゾチアゾール誘導体
|
|
SK5212003A3
(en)
|
2000-10-02 |
2004-03-02 |
Janssen Pharmaceutica Nv |
Metabotropic glutamate receptor antagonists
|
|
DE10058663A1
(de)
|
2000-11-25 |
2002-05-29 |
Merck Patent Gmbh |
Verwendung von Thienopyrimidinen
|
|
JPWO2002051849A1
(ja)
|
2000-12-26 |
2004-04-22 |
第一製薬株式会社 |
Ｃｄｋ４活性阻害剤
|
|
KR20030070082A
(ko)
|
2000-12-28 |
2003-08-27 |
시오노기세이야쿠가부시키가이샤 |
칸나비노이드 2형 수용체 친화 작용을 갖는 피리돈 유도체
|
|
JP2002308882A
(ja)
|
2001-02-08 |
2002-10-23 |
Yamanouchi Pharmaceut Co Ltd |
チエノピリミジン誘導体
|
|
AU2002258400A1
(en)
|
2001-02-16 |
2002-08-28 |
Tularik Inc. |
Methods of using pyrimidine-based antiviral agents
|
|
WO2002070662A2
(en)
|
2001-03-02 |
2002-09-12 |
Gpc Biotech Ag |
Three hybrid assay system
|
|
DE10291003D2
(de)
|
2001-03-08 |
2004-04-15 |
Ilfa Industrieelektronik Und L |
Mehrschichtige Leiterplatte
|
|
US6831074B2
(en)
|
2001-03-16 |
2004-12-14 |
Pfizer Inc |
Pharmaceutically active compounds
|
|
US6596731B2
(en)
|
2001-03-27 |
2003-07-22 |
Hoffmann-La Roche Inc. |
Substituted imidazo[1,2-A] pyridine derivatives
|
|
CA2443144A1
(en)
|
2001-04-02 |
2002-10-10 |
Merck & Co., Inc. |
In vivo methods of determining activity of receptor-type kinase inhibitors
|
|
KR100566178B1
(ko)
|
2001-04-12 |
2006-03-29 |
에프. 호프만-라 로슈 아게 |
ｍＧｌｕＲ2 길항물질 Ｉ로서의디하이드로-벤조[ｂ][1,4]디아제핀-2-온 유도체
|
|
EP1379511B1
(en)
|
2001-04-12 |
2005-07-20 |
F. Hoffmann-La Roche Ag |
DIHYDRO-BENZO (b) (1, 4) DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II
|
|
SE0101579D0
(sv)
|
2001-05-04 |
2001-05-04 |
Astrazeneca Ab |
New compounds
|
|
PL366577A1
(en)
|
2001-05-14 |
2005-02-07 |
Bristol-Myers Squibb Pharma Company |
Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands
|
|
WO2002094264A1
(en)
|
2001-05-23 |
2002-11-28 |
Tularik Inc. |
Ccr4 antagonists
|
|
US20030027820A1
(en)
|
2001-05-30 |
2003-02-06 |
Alteon, Inc. |
Method for treating fibrotic diseases or other indications V
|
|
EP1414464A4
(en)
|
2001-05-30 |
2005-06-22 |
Alteon Inc |
METHOD OF TREATING GLAUCOMA
|
|
US20030114448A1
(en)
|
2001-05-31 |
2003-06-19 |
Millennium Pharmaceuticals, Inc. |
Inhibitors of factor Xa
|
|
CA2446193C
(en)
|
2001-06-05 |
2011-11-01 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
1,4-disubstituted benzo-fused cycloalkyl urea compounds
|
|
JPWO2002102807A1
(ja)
|
2001-06-14 |
2004-09-30 |
萬有製薬株式会社 |
新規イソキサゾロピリドン誘導体及びその用途
|
|
CA2450934A1
(en)
|
2001-06-19 |
2002-12-27 |
Marco Dodier |
Pyrimidine inhibitors of phosphodiesterase (pde) 7
|
|
JP2003012653A
(ja)
|
2001-06-28 |
2003-01-15 |
Yamanouchi Pharmaceut Co Ltd |
キナゾリン誘導体
|
|
US6750350B2
(en)
|
2001-08-02 |
2004-06-15 |
Neurocrine Biosciences, Inc. |
Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
|
|
US7427623B2
(en)
|
2001-09-11 |
2008-09-23 |
Smithkline Beecham Corporation |
4-Amino-2,3-disubstituted thieno[2,3-d]pyrimidines and pharmacetical compositions thereof
|
|
DE60228103D1
(de)
|
2001-10-02 |
2008-09-18 |
Smithkline Beecham Corp |
Chemische verbindungen
|
|
TWI330183B
(es)
|
2001-10-22 |
2010-09-11 |
Eisai R&D Man Co Ltd |
|
|
TW200406466A
(en)
|
2001-11-13 |
2004-05-01 |
Ciba Sc Holding Ag |
Compositions comprising at least one oxonol dye and at least one metal complex
|
|
US6921762B2
(en)
|
2001-11-16 |
2005-07-26 |
Amgen Inc. |
Substituted indolizine-like compounds and methods of use
|
|
GB0129260D0
(en)
|
2001-12-06 |
2002-01-23 |
Eisai London Res Lab Ltd |
Pharmaceutical compositions and their uses
|
|
BR0214967A
(pt)
|
2001-12-14 |
2005-05-10 |
Novo Nordisk As |
Composto, sal famaceuticamente aceitável, processo para a preparação de um composto, composição farmacêutica, uso de um composto e método de tratar um distúrbio de um paciente
|
|
ES2421511T3
(es)
|
2001-12-21 |
2013-09-03 |
X Ceptor Therapeutics Inc |
Moduladores de LXR
|
|
PL208123B1
(pl)
|
2001-12-27 |
2011-03-31 |
Taisho Pharmaceutical Co Ltd |
Pochodna kwasu 2-amino-3-alkoksy-6-fluorobicyklo [3.1.0] heksano-2, 6-dikarboksylowego, zawierająca ją kompozycja farmaceutyczna i lek, oraz jej zastosowanie
|
|
DE10164139A1
(de)
|
2001-12-27 |
2003-07-10 |
Bayer Ag |
2-Heteroarylcarbonsäureamide
|
|
JP2005170790A
(ja)
|
2002-01-09 |
2005-06-30 |
Ajinomoto Co Inc |
Ｎ−アルキルスルフォニル置換アミド誘導体
|
|
EP1465862A1
(en)
|
2002-01-17 |
2004-10-13 |
SmithKline Beecham Corporation |
Cycloalkyl ketoamides derivatives useful as cathepsin k inhibitors
|
|
WO2003062392A2
(en)
|
2002-01-18 |
2003-07-31 |
Ceretek Llc |
Methods of treating conditions associated with an edg receptor
|
|
US20050113283A1
(en)
|
2002-01-18 |
2005-05-26 |
David Solow-Cordero |
Methods of treating conditions associated with an EDG-4 receptor
|
|
WO2003064428A1
(en)
|
2002-01-29 |
2003-08-07 |
H. Lundbeck A/S |
Furano- and thienopyrimidines as neurokinase inhibitors
|
|
US6949542B2
(en)
|
2002-02-06 |
2005-09-27 |
Hoffman-La Roche Inc. |
Dihydro-benzo[b][1,4]diazepin-2-one derivatives
|
|
AU2003210869A1
(en)
|
2002-02-07 |
2003-09-02 |
University Of Miami |
Schwann cell and phosphodiesterase inhibitors based therapy
|
|
US20040116489A1
(en)
|
2002-02-12 |
2004-06-17 |
Massey Steven Marc |
Synthetic excitatory amino acids
|
|
CA2476162A1
(en)
|
2002-02-13 |
2003-08-21 |
Takeda Chemical Industries, Ltd. |
Jnk inhibitor
|
|
PL218749B1
(pl)
|
2002-02-14 |
2015-01-30 |
Pharmacia Corp |
Pochodna pirydynonu oraz jej zastosowanie do wytwarzania leku
|
|
WO2003070712A1
(en)
|
2002-02-19 |
2003-08-28 |
H. Lundbeck A/S |
Thioibotenic acid and derivatives thereof
|
|
US6833380B2
(en)
|
2002-03-07 |
2004-12-21 |
Warner-Lambert Company, Llc |
Compounds that modulate PPAR activity and methods of preparation
|
|
JP2005526068A
(ja)
|
2002-03-14 |
2005-09-02 |
バイエル・ヘルスケア・アクチェンゲゼルシャフト |
抗炎症剤としての単環式アロイルピリジノン類
|
|
AU2003225964B2
(en)
|
2002-03-28 |
2008-11-20 |
Merck Sharp & Dohme Corp. |
Substituted 2,3-diphenyl pyridines
|
|
WO2003082350A2
(en)
|
2002-03-29 |
2003-10-09 |
Janssen Pharmaceutica N.V. |
Radiolabelled quinoline and quinolinone derivatives and their use as metabotropic glutamate receptor ligands
|
|
JP2005528378A
(ja)
|
2002-04-03 |
2005-09-22 |
イーライ・リリー・アンド・カンパニー |
非定型抗精神病薬およびｍＧＬＵ２／３受容体アゴニストを組み合わせた精神病治療
|
|
US6864261B2
(en)
|
2002-05-02 |
2005-03-08 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
|
US7125888B2
(en)
|
2002-05-02 |
2006-10-24 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
|
MXPA04011470A
(es)
|
2002-05-21 |
2005-02-14 |
Amgen Inc |
Compuestos heterociclicos sustituidos y metodos de uso.
|
|
PL221489B1
(pl)
|
2002-06-11 |
2016-04-29 |
Lilly Co Eli |
Kwas (1R, 4S, 5S, 6S)-4-(2<sup>'</sup>S-4<sup>'</sup>-metylotio-2<sup>'</sup>-aminobutanoilo)amino-2,2-diokso-2λ<sup>6</sup>-tia-bicyklo[3.1.0]heksano-4,6-dikarboksylowy, jego hydrat, zastosowanie, oraz kompozycja farmaceutyczna zawierająca te związki do leczenia zaburzeń neurologicznych i psychiatrycznych
|
|
RU2333208C2
(ru)
|
2002-06-13 |
2008-09-10 |
Вертекс Фармасьютикалз Инкорпорейтед |
Производные 2-уреидо-6-гетероарил-3н-бензимидазол-6-карбоновой кислоты и родственные соединения в качестве ингибиторов гиразы и/или топоизомеразы iv для лечения бактериальных инфекций
|
|
MY141867A
(en)
|
2002-06-20 |
2010-07-16 |
Vertex Pharma |
Substituted pyrimidines useful as protein kinase inhibitors
|
|
GB0214268D0
(en)
|
2002-06-20 |
2002-07-31 |
Celltech R&D Ltd |
Chemical compounds
|
|
EP1545523A1
(en)
|
2002-07-03 |
2005-06-29 |
Astex Technology Limited |
3-&-grave;(HETERO) ARYLMETHOXY ! PYRIDINES AND THEIR ANALOGUES ASP38 MAP KINASE INHIBITORS
|
|
US7262194B2
(en)
|
2002-07-26 |
2007-08-28 |
Euro-Celtique S.A. |
Therapeutic agents useful for treating pain
|
|
US20040138238A1
(en)
|
2002-08-08 |
2004-07-15 |
Dhanoa Dale S. |
Substituted aminopyrimidine compounds as neurokinin antagonists
|
|
GB0218630D0
(en)
|
2002-08-10 |
2002-09-18 |
Tanabe Seiyaku Co |
Novel compounds
|
|
GB0218800D0
(en)
|
2002-08-13 |
2002-09-18 |
Celltech R&D Ltd |
Chemical compounds
|
|
WO2004017950A2
(en)
|
2002-08-22 |
2004-03-04 |
Piramed Limited |
Phosphadidylinositol 3,5-biphosphate inhibitors as anti-viral agents
|
|
JP2006502143A
(ja)
|
2002-08-26 |
2006-01-19 |
メルク エンド カムパニー インコーポレーテッド |
向代謝型グルタミン酸受容体のアセトフェノン増強因子
|
|
AU2003258305A1
(en)
|
2002-08-28 |
2004-03-19 |
Intermune, Inc. |
Combination therapy for treatment of fibrotic disorders
|
|
MY139563A
(en)
|
2002-09-04 |
2009-10-30 |
Bristol Myers Squibb Co |
Heterocyclic aromatic compounds useful as growth hormone secretagogues
|
|
AU2003270166A1
(en)
|
2002-09-10 |
2004-04-30 |
Novartis Ag |
Mglu receptors antagonists for treating disorders associated with mglu receptors including addiction and depression
|
|
EP1546201A4
(en)
|
2002-09-11 |
2006-08-16 |
Merck & Co Inc |
NUCLEIC ACID SEQUENCES CODING TO MGLUR2 AND MGLUR3 FOR NEW POINT MUTATIONS
|
|
CA2495721C
(en)
|
2002-09-19 |
2009-08-18 |
Boehringer Ingelheim (Canada) Ltd. |
Non-nucleoside reverse transcriptase inhibitors
|
|
WO2004026875A1
(en)
|
2002-09-19 |
2004-04-01 |
Boehringer Ingelheim (Canada) Ltd. |
Non-nucleoside reverse transcriptase inhibitors
|
|
AR044743A1
(es)
|
2002-09-26 |
2005-10-05 |
Nihon Nohyaku Co Ltd |
Herbicida, metodo de emplearlo, derivados de tienopirimidina sustituida,compuestos intermediarios, y procedimientos que se utilizan para producirlos,
|
|
US7067658B2
(en)
|
2002-09-30 |
2006-06-27 |
Bristol-Myers Squibb Company |
Pyridino and pyrimidino pyrazinones
|
|
US7998163B2
(en)
|
2002-10-03 |
2011-08-16 |
Boston Scientific Scimed, Inc. |
Expandable retrieval device
|
|
US7329520B2
(en)
|
2002-10-23 |
2008-02-12 |
Daiichi Pure Chemicals Co., Ltd. |
Fructosyl peptide oxidase and utilization thereof
|
|
US20040138204A1
(en)
|
2002-10-30 |
2004-07-15 |
Harrington James Frederick |
Compositions and methods for pain reduction
|
|
PL376823A1
(pl)
|
2002-11-01 |
2006-01-09 |
Abbott Laboratories |
Środki przeciwzakaźne
|
|
US7902203B2
(en)
|
2002-11-01 |
2011-03-08 |
Abbott Laboratories, Inc. |
Anti-infective agents
|
|
US6930117B2
(en)
|
2002-11-09 |
2005-08-16 |
The Procter & Gamble Company |
N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones
|
|
ES2412273T3
(es)
|
2002-11-21 |
2013-07-10 |
Novartis Ag |
Inhibidores de 2-morfolín-4-pirimidinas como inhibidores de fosfotidilinositol (PI) 3-quinasa y su uso en el tratamiento del cáncer.
|
|
AU2003289386A1
(en)
|
2002-12-18 |
2004-07-09 |
Takeda Pharmaceutical Company Limited |
Jnk inhibitors
|
|
BR0317885A
(pt)
|
2002-12-30 |
2005-12-06 |
Celgene Corp |
Composto, isÈmeros s e r enantiomericamente puros do mesmo, composição farmacêutica e métodos de inibir pde4 e mmp, de modular a produção de tnf-alfa, de tratar ou prevenir mds, de tratar doença mieloproliferativa, angiogênese indesejada, câncer, uma doença, inflamação dos pulmões, depressão, distúrbio pulmonar obstrutivo crÈnico, doença inflamatória do intestino, dermatite atópica, psorìase, doença de crohn, artrite reumatóide, asma, eslcerose múltipla e doença cardìaca em um mamìfero e de tratar, prevenir ou controlar a sìndrome de dor regional complexa
|
|
NZ540612A
(en)
|
2003-01-14 |
2008-02-29 |
Arena Pharm Inc |
1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
|
|
ITMI20030151A1
(it)
|
2003-01-30 |
2004-07-31 |
Recordati Ind Chimica E Farma Ceutica S P A |
Uso di antagonisti selettivi del recettore mglu5 per il trattamento di disfunzioni neuromuscolari del tratto urinario inferiore.
|
|
EP1592684B1
(en)
|
2003-02-04 |
2008-07-30 |
F. Hoffmann-La Roche Ag |
Malonamide derivatives as gamma-secretase inhibitors
|
|
DE10306250A1
(de)
|
2003-02-14 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
SI1606282T1
(sl)
|
2003-02-24 |
2009-04-30 |
Arena Pharm Inc |
Fenilni in piridilpiperidinski derivati kot modulatorji glukoznega metabolizma
|
|
JP2006515341A
(ja)
|
2003-03-03 |
2006-05-25 |
エフ．ホフマン−ラ ロシュ アーゲー |
５−ｈｔ６調節物質として使用するための２，５−および２，６−置換テトラヒドロイソキノリン
|
|
ITFI20030058A1
(it)
|
2003-03-06 |
2004-09-07 |
Univ Firenze |
Formulazioni farmaceutiche contenenti tiazolidinedioni
|
|
DE10311065A1
(de)
|
2003-03-13 |
2004-09-23 |
Abbott Gmbh & Co. Kg |
Pyrimidin-2-on-Verbindungen und ihre therapeutische Verwendung
|
|
WO2004092123A2
(en)
|
2003-04-10 |
2004-10-28 |
Microbia, Inc. |
Inhibitors of fungal invasion
|
|
WO2004092135A2
(en)
|
2003-04-15 |
2004-10-28 |
Astrazeneca |
Substituted benzosulphonamide as potentiators of glutamate receptors
|
|
JP2004339080A
(ja)
|
2003-05-13 |
2004-12-02 |
Tokyo Institute Of Technology |
ピラゾ−ル誘導体を含有する高血圧治療剤
|
|
WO2004110350A2
(en)
|
2003-05-14 |
2004-12-23 |
Torreypines Therapeutics, Inc. |
Compouds and uses thereof in modulating amyloid beta
|
|
WO2005040337A2
(en)
|
2003-05-20 |
2005-05-06 |
The Regents Of The University Of California |
METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES
|
|
GB0315950D0
(en)
|
2003-06-11 |
2003-08-13 |
Xention Discovery Ltd |
Compounds
|
|
EP1680125A1
(en)
|
2003-07-02 |
2006-07-19 |
Warner-Lambert Company LLC |
Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
|
|
TWI372050B
(en)
|
2003-07-03 |
2012-09-11 |
Astex Therapeutics Ltd |
(morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles
|
|
WO2005007144A2
(en)
|
2003-07-14 |
2005-01-27 |
Decode Genetics Ehf |
Method of diagnosis and treatment for asthma based on haplotype association
|
|
NZ546044A
(en)
|
2003-08-29 |
2009-09-25 |
Vernalis Cambridge Ltd |
Pyrimidothiophene compounds
|
|
GB0320300D0
(en)
|
2003-08-29 |
2003-10-01 |
Cancer Rec Tech Ltd |
Pyrimidothiophene compounds
|
|
GB0322016D0
(en)
|
2003-09-19 |
2003-10-22 |
Merck Sharp & Dohme |
New compounds
|
|
WO2005061507A1
(en)
|
2003-12-16 |
2005-07-07 |
Pfizer Products Inc. |
Bicyclic pyrazol-4-one cannabinoid receptor ligands and uses thereof
|
|
MXPA06009019A
(es)
|
2004-02-18 |
2007-03-08 |
Astrazeneca Ab |
Compuestos de tetrazol y su uso como antagonistas del receptor de glutamato metabotropico.
|
|
DE102004009039A1
(de)
|
2004-02-23 |
2005-09-08 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
|
|
US7306631B2
(en)
|
2004-03-30 |
2007-12-11 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
BRPI0509795A
(pt)
|
2004-04-12 |
2007-10-23 |
Sankyo Co |
composto ou um sal farmacologicamente aceitável do mesmo, composição farmacêutica, uso do composto ou sal farmacologicamente aceitável do mesmo, e, método para promover osteogênese, supressão de ressorção óssea e/ou melhoramento da densidade óssea
|
|
US7459562B2
(en)
|
2004-04-23 |
2008-12-02 |
Bristol-Myers Squibb Company |
Monocyclic heterocycles as kinase inhibitors
|
|
GB0413605D0
(en)
|
2004-06-17 |
2004-07-21 |
Addex Pharmaceuticals Sa |
Novel compounds
|
|
US8063004B2
(en)
|
2004-07-22 |
2011-11-22 |
Malcera, L.L.C. |
Chemical composition of matter for the liquefaction and dissolution of asphaltene and paraffin sludges into petroleum crude oils and refined products at ambient temperatures and method of use
|
|
JP2008508306A
(ja)
|
2004-07-30 |
2008-03-21 |
メルク エンド カムパニー インコーポレーテッド |
メタボトロピックグルタミン酸受容体のインダノン増強剤
|
|
AU2005269546A1
(en)
|
2004-07-30 |
2006-02-09 |
Merck & Co., Inc. |
Heterocyclic acetophenone potentiators of metabotropic glutamate receptors
|
|
MX2007001341A
(es)
|
2004-08-02 |
2007-04-23 |
Sanol Arznei Schwarz Gmbh |
Carboxamidas de indolizina y sus derivados aza y diaza.
|
|
US20080097210A1
(en)
|
2004-08-11 |
2008-04-24 |
Koninklijke Philips Electronics N.V. |
Ultrasonic Diagnosis of Ischemic Cardiodisease
|
|
TW200613272A
(en)
|
2004-08-13 |
2006-05-01 |
Astrazeneca Ab |
Isoindolone compounds and their use as metabotropic glutamate receptor potentiators
|
|
BRPI0514391A
(pt)
|
2004-08-18 |
2008-06-10 |
Pharmacia & Upjohn Co Llc |
compostos de triazolopiridina para o tratamento de inflamação
|
|
DE102004044884A1
(de)
|
2004-09-14 |
2006-05-24 |
Grünenthal GmbH |
Substituierte bizyklische Imidazo-3-yl-amin-Verbindungen
|
|
WO2006030847A1
(ja)
|
2004-09-17 |
2006-03-23 |
Dainippon Sumitomo Pharma Co., Ltd. |
新規二環性ピラゾール誘導体
|
|
GB0420722D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
US20080096935A1
(en)
|
2004-10-25 |
2008-04-24 |
Pinkerton Anthony B |
Heterocyclic Indanone Potentiators of Metabotropic Glutamate Receptors
|
|
DE102004054665A1
(de)
|
2004-11-12 |
2006-05-18 |
Bayer Cropscience Gmbh |
Substituierte bi- und tricyclische Pyrazol-Derivate Verfahren zur Herstellung und Verwendung als Herbizide und Pflanzenwachstumsregulatoren
|
|
US7718921B2
(en)
|
2004-11-17 |
2010-05-18 |
Metal Improvement Company Llc |
Active beam delivery system with variable optical path segment through air
|
|
DK1817301T3
(da)
|
2004-11-22 |
2012-02-27 |
Lilly Co Eli |
Forstærkere af glutamat-receptorer
|
|
US7434262B2
(en)
|
2004-12-08 |
2008-10-07 |
At&T Intellectual Property I, L.P. |
Methods and systems that selectively resurrect blocked communications between devices
|
|
DE102004061288A1
(de)
|
2004-12-14 |
2006-06-29 |
Schering Ag |
3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel
|
|
MX2007007220A
(es)
|
2004-12-27 |
2007-08-20 |
Astrazeneca Ab |
Compuestos de pirazolona como agonistas de receptor de glutamato metabotropico para el tratamiento de trastornos neurologicos y psiquiatricos.
|
|
US7456289B2
(en)
|
2004-12-31 |
2008-11-25 |
National Health Research Institutes |
Anti-tumor compounds
|
|
WO2006091496A2
(en)
|
2005-02-24 |
2006-08-31 |
Merck & Co., Inc. |
Benzazole potentiators of metabotropic glutamate receptors
|
|
CA2602444C
(en)
|
2005-03-23 |
2013-03-19 |
F.Hoffmann-La Roche Ag |
Acetylenyl-pyrazolo-pyrimidine derivatives as mglur2 antagonists
|
|
EP1875912A4
(en)
|
2005-04-08 |
2008-06-04 |
Eisai R&D Man Co Ltd |
MEANS OF TREATING UNWILLING MOVEMENTS
|
|
US7572807B2
(en)
|
2005-06-09 |
2009-08-11 |
Bristol-Myers Squibb Company |
Heteroaryl 11-beta-hydroxysteroid dehydrogenase type I inhibitors
|
|
US7579360B2
(en)
|
2005-06-09 |
2009-08-25 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
JPWO2006137350A1
(ja)
|
2005-06-22 |
2009-01-15 |
キッセイ薬品工業株式会社 |
新規なフロピリジン誘導体、それを含有する医薬組成物およびそれらの用途
|
|
RU2008101923A
(ru)
|
2005-08-05 |
2009-09-10 |
Астразенека Аб (Se) |
Трициклические бензимидазолы и их применение в качестве модуляторов метаботропного глутаматного рецептора
|
|
JP5031745B2
(ja)
|
2005-08-12 |
2012-09-26 |
アストラゼネカ アクチボラグ |
代謝型グルタミン酸受容体増強性イソインドロン
|
|
WO2007027669A1
(en)
|
2005-08-29 |
2007-03-08 |
Cps Biofuels, Inc. |
Improved biodiesel fuel, additives, and lubbricants
|
|
ES2328630T3
(es)
|
2005-09-17 |
2009-11-16 |
Novartis Ag |
Derivados de 5-amino-4-hydroxi-7-(imidazo (1,2-a>)piridin-6- ilmetil-8-metil-nonamida y compuestos relacionados como inhibidores de la renina para el tratamiento de la hipertension.
|
|
EP1764099A3
(en)
|
2005-09-17 |
2007-05-09 |
Speedel Experimenta AG |
Diaminoalcohol derivatives for the treatment of Alzheimer, malaria, HIV
|
|
US8492428B2
(en)
|
2005-09-20 |
2013-07-23 |
Mayo Foundation For Medical Education And Research |
Small-molecule botulinum toxin inhibitors
|
|
KR101121292B1
(ko)
|
2005-09-27 |
2012-04-13 |
에프. 호프만-라 로슈 아게 |
Ｍｇｌｕｒ2 길항제로서 옥사다이아졸일 피라졸로-피리미딘
|
|
RU2592703C9
(ru)
|
2005-11-15 |
2016-10-20 |
Эррей Байофарма Инк. |
ИНГИБИТОРЫ ТИПА ErbB
|
|
AR057218A1
(es)
|
2005-12-15 |
2007-11-21 |
Astra Ab |
Compuestos de oxazolidinona y su uso como pontenciadores del receptor metabotropico de glutamato
|
|
US7998959B2
(en)
|
2006-01-12 |
2011-08-16 |
Incyte Corporation |
Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
|
|
US7553836B2
(en)
*
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
TW200804281A
(en)
|
2006-02-16 |
2008-01-16 |
Astrazeneca Ab |
New metabotropic glutamate receptor-potentiating isoindolones
|
|
EP1993539A4
(en)
|
2006-03-02 |
2010-05-19 |
Glaxosmithkline Llc |
THIAZOLONE AS A PI3 KINASE INHIBITOR
|
|
AR059898A1
(es)
|
2006-03-15 |
2008-05-07 |
Janssen Pharmaceutica Nv |
Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
|
|
GB0606774D0
(en)
|
2006-04-03 |
2006-05-10 |
Novartis Ag |
Organic compounds
|
|
GB0608263D0
(en)
|
2006-04-26 |
2006-06-07 |
Glaxo Group Ltd |
Compounds
|
|
WO2007135527A2
(en)
|
2006-05-23 |
2007-11-29 |
Pfizer Products Inc. |
Benzimidazolyl compounds
|
|
WO2007135529A2
(en)
|
2006-05-23 |
2007-11-29 |
Pfizer Products Inc. |
Azabenzimidazolyl compounds as mglur2 potentiators
|
|
ATE556061T1
(de)
|
2006-06-19 |
2012-05-15 |
Toray Industries |
Therapeutisches oder prophylaktisches mittel gegen multiple sklerose
|
|
WO2008001115A2
(en)
|
2006-06-29 |
2008-01-03 |
Astex Therapeutics Limited |
Pharmaceutical combinations of 1-cyclopropyl-3- [3- (5-m0rphoolin-4-ylmethyl-1h-benzoimidazol-2-yl) -lh-1-pyrazol- 4-yl] -urea
|
|
CA2656855A1
(en)
|
2006-07-12 |
2008-01-17 |
Christoph Luthy |
Triazolopyridine derivatives as herbicides
|
|
US8198448B2
(en)
|
2006-07-14 |
2012-06-12 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
|
PE20080403A1
(es)
|
2006-07-14 |
2008-04-25 |
Amgen Inc |
Derivados heterociclicos fusionados y metodos de uso
|
|
WO2008012622A2
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Azabenzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
CN101511802A
(zh)
|
2006-09-13 |
2009-08-19 |
阿斯利康(瑞典)有限公司 |
螺唑烷酮化合物及其作为代谢型谷氨酸受体增效剂的用途
|
|
CA2665195C
(en)
|
2006-10-11 |
2011-08-09 |
Amgen Inc. |
Imidazo- and triazolo-pyridine compounds and methods of use thereof
|
|
US7994190B2
(en)
|
2006-11-01 |
2011-08-09 |
Bristol-Myers Squibb Company |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
|
TW200831085A
(en)
|
2006-12-13 |
2008-08-01 |
Merck & Co Inc |
Non-nucleoside reverse transcriptase inhibitors
|
|
WO2008078091A1
(en)
|
2006-12-22 |
2008-07-03 |
Astex Therapeutics Limited |
Bicyclic heterocyclic compounds as fgfr inhibitors
|
|
EP2121687B1
(en)
|
2006-12-22 |
2015-10-14 |
Astex Therapeutics Limited |
Tricyclic amine derivatives as protein tyrosine kinase inhibitors
|
|
US20110053953A1
(en)
|
2007-02-09 |
2011-03-03 |
Abdelmalik Slassi |
AZA-Isoindolones and Their Use as Metabotropic Glutamate Receptor Potentiators - 613
|
|
ES2320955B1
(es)
|
2007-03-02 |
2010-03-16 |
Laboratorios Almirall S.A. |
Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida.
|
|
TW200900065A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
|
|
TW200900391A
(en)
|
2007-03-07 |
2009-01-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-phenyl-piperidin-1-yl)-pyridin-2-one derivatives
|
|
BRPI0808445A2
(pt)
|
2007-03-07 |
2014-08-05 |
Janssen Pharmaceutica Nv |
TIAZOLIDINADIONAS COMO MODULADORES DE RECEPTOR-a RELACIONADOS COM ESTROGÊNIO
|
|
CA2680212A1
(en)
|
2007-03-07 |
2008-09-12 |
Janssen Pharmaceutica N.V. |
Substituted phenoxy aminothiazolones as estrogen related receptor-.alpha. modulators
|
|
SI2132188T1
(sl)
|
2007-03-07 |
2012-04-30 |
Janssen Pharmaceutica Nv |
Substituiran fenoksi n-alkilirani tiazoldinedioni kot z estrogenom povezani receptor-alfa modulatorji
|
|
TW200845978A
(en)
|
2007-03-07 |
2008-12-01 |
Janssen Pharmaceutica Nv |
3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives
|
|
GB0704407D0
(en)
|
2007-03-07 |
2007-04-18 |
Glaxo Group Ltd |
Compounds
|
|
AU2008226649B2
(en)
|
2007-03-09 |
2013-08-01 |
Sanofi |
Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
|
|
WO2008124085A2
(en)
|
2007-04-03 |
2008-10-16 |
Exelixis, Inc. |
Methods of using combinations of mek and jak-2 inhibitors
|
|
WO2008130853A1
(en)
|
2007-04-17 |
2008-10-30 |
Astrazeneca Ab |
Hydrazides and their use as metabotropic glutamate receptor potentiators - 681
|
|
WO2008141239A1
(en)
|
2007-05-10 |
2008-11-20 |
Acadia Pharmaceuticals Inc. |
Imidazol [1,2-a] pyridines and related compounds with activity at cannabinoid cb2 receptors
|
|
BRPI0812163A2
(pt)
|
2007-05-25 |
2014-12-16 |
Abbott Gmbh & Co Kg |
Compostos heterocíclicos como moduladores positivos do receptor metabotrópico de glutamato 2 (receptor mglu2)
|
|
TWI417100B
(zh)
|
2007-06-07 |
2013-12-01 |
Astrazeneca Ab |
二唑衍生物及其作為代謝型麩胺酸受體增效劑-８４２之用途
|
|
TW200911255A
(en)
|
2007-06-07 |
2009-03-16 |
Astrazeneca Ab |
Metabotropic glutamate receptor oxadiazole ligands and their use as potentiators-841
|
|
WO2009004430A1
(en)
|
2007-06-29 |
2009-01-08 |
Pfizer Inc. |
N-benzyl oxazolidinones and related heterocycleic compounds as potentiators of glutamate receptors
|
|
US20090017943A1
(en)
|
2007-07-13 |
2009-01-15 |
Ken Landry |
Golf green reader
|
|
BRPI0816970A2
(pt)
|
2007-09-14 |
2015-03-24 |
Ortho Mcneil Janssen Pharm |
1,3-dissubstituídas-4-fenil-1h-piridin-2-onas
|
|
WO2009033704A1
(en)
|
2007-09-14 |
2009-03-19 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc. |
1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h, 1'h-[1, 4'] bipyridinyl-2'-ones
|
|
CN101848893B
(zh)
|
2007-09-14 |
2012-06-06 |
奥梅-杨森制药有限公司 |
1,3-二取代的4-(芳基-x-苯基)-1h-吡啶-2-酮
|
|
WO2009041567A1
(ja)
|
2007-09-27 |
2009-04-02 |
Banyu Pharmaceutical Co., Ltd. |
メラニン凝集ホルモン受容体拮抗作用を有するジアリールケチミン誘導体
|
|
US8119658B2
(en)
|
2007-10-01 |
2012-02-21 |
Bristol-Myers Squibb Company |
Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
JP5433582B2
(ja)
|
2007-11-14 |
2014-03-05 |
ジャンセン ファーマシューティカルズ， インコーポレイテッド． |
イミダゾ［１，２−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体の正のアロステリック調節因子としてのその使用
|
|
JP2011510083A
(ja)
|
2008-01-24 |
2011-03-31 |
メルク・シャープ・エンド・ドーム・コーポレイション |
３，５−二置換−１，３−オキサゾリジン−２−オン誘導体
|
|
EP2085390A1
(en)
|
2008-01-31 |
2009-08-05 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Labelled analogues of halobenzamides as multimodal radiopharmaceuticals and their precursors
|
|
US9446995B2
(en)
|
2012-05-21 |
2016-09-20 |
Illinois Institute Of Technology |
Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
|
|
WO2009110901A1
(en)
|
2008-03-06 |
2009-09-11 |
Sanofi-Aventis |
Substituted dihydro, trihydro and tetrahydro cycloalkyloxazolopyrimidinones, preparation and use thereof as allosteric modulators of mglur
|
|
KR101673621B1
(ko)
|
2008-03-24 |
2016-11-07 |
노파르티스 아게 |
아릴술폰아미드-계 매트릭스 메탈로프로테아제 억제제
|
|
DE102008001056A1
(de)
|
2008-04-08 |
2009-10-15 |
Robert Bosch Gmbh |
Umlenkeinrichtung für einen Strahl einer elektromagnetischen Welle
|
|
WO2009130232A1
(en)
|
2008-04-24 |
2009-10-29 |
Glaxo Group Limited |
Pyrazolo [1, 5 -a] pyrazine derivatives as antagonists of v1b receptors
|
|
US20110124661A1
(en)
|
2008-05-15 |
2011-05-26 |
Merck Sharp & Dohme Corp. |
Oxazolobenzimidazole derivatives
|
|
JP2011520892A
(ja)
|
2008-05-15 |
2011-07-21 |
メルク・シャープ・エンド・ドーム・コーポレイション |
オキサゾロベンゾイミダゾール誘導体
|
|
US7790760B2
(en)
|
2008-06-06 |
2010-09-07 |
Astrazeneca Ab |
Metabotropic glutamate receptor isoxazole ligands and their use as potentiators 286
|
|
TW201006801A
(en)
|
2008-07-18 |
2010-02-16 |
Lilly Co Eli |
Imidazole carboxamides
|
|
UY32049A
(es)
|
2008-08-14 |
2010-03-26 |
Takeda Pharmaceutical |
Inhibidores de cmet
|
|
WO2010022081A1
(en)
|
2008-08-19 |
2010-02-25 |
Array Biopharma Inc. |
Triazolopyridine compounds as pim kinase inhibitors
|
|
TWI496779B
(zh)
|
2008-08-19 |
2015-08-21 |
Array Biopharma Inc |
作為ｐｉｍ激酶抑制劑之三唑吡啶化合物
|
|
JPWO2010024258A1
(ja)
|
2008-08-29 |
2012-01-26 |
塩野義製薬株式会社 |
Ｐｉ３ｋ阻害活性を有する縮環アゾール誘導体
|
|
WO2010025890A1
(en)
|
2008-09-02 |
2010-03-11 |
Ortho-Mcneil-Janssen Pharmaceuticals, Inc |
3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors
|
|
MX2011003691A
(es)
|
2008-10-16 |
2011-09-06 |
Ortho Mcneil Janssen Pharm |
Derivados de indol y benzomorfolina como moduladores de los receptores de glutamato metabotropico.
|
|
EP2373649B1
(en)
|
2008-11-28 |
2013-01-23 |
Janssen Pharmaceuticals, Inc. |
Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors
|
|
AT507619B1
(de)
|
2008-12-05 |
2011-11-15 |
Oesterreichisches Forschungs Und Pruefzentrum Arsenal Ges M B H |
Verfahren zur approximation des zeitlichen verlaufs von verkehrsdaten
|
|
US8637505B2
(en)
|
2009-02-04 |
2014-01-28 |
Boehringer Ingelheim International Gmbh |
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
|
|
WO2010114726A1
(en)
|
2009-03-31 |
2010-10-07 |
Merck Sharp & Dohme Corp. |
Aminobenzotriazole derivatives
|
|
EP2417135A1
(en)
|
2009-04-07 |
2012-02-15 |
Schering Corporation |
Substituted triazolopyridines and analogs thereof
|
|
MY153913A
(en)
*
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
CN102439008B
(zh)
|
2009-05-12 |
2015-04-29 |
杨森制药有限公司 |
1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途
|
|
MY153912A
(en)
*
|
2009-05-12 |
2015-04-15 |
Janssen Pharmaceuticals Inc |
1, 2, 4,-triazolo[4,3-a[pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
|
|
WO2010141360A1
(en)
|
2009-06-05 |
2010-12-09 |
Merck Sharp & Dohme Corp. |
Biaryl benzotriazole derivatives
|
|
US8975286B2
(en)
|
2009-08-20 |
2015-03-10 |
Merck Sharp & Dohme Corp. |
Ether benzotriazole derivatives
|
|
CN102002040A
(zh)
|
2009-09-01 |
2011-04-06 |
上海药明康德新药开发有限公司 |
一种三唑并吡啶环化合物的合成方法
|
|
AR078171A1
(es)
|
2009-09-15 |
2011-10-19 |
Sanofi Aventis |
Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas
|
|
AR078173A1
(es)
|
2009-09-15 |
2011-10-19 |
Sanofi Aventis |
Bifeniloximetil dihidro oxazolopirimidinonas sustituidas, su preparacion y su uso
|
|
WO2011034741A1
(en)
|
2009-09-15 |
2011-03-24 |
Merck Sharp & Dohme Corp. |
Imidazopyridin-2-one derivatives
|
|
AR078172A1
(es)
|
2009-09-15 |
2011-10-19 |
Sanofi Aventis |
Fenoximetil dihidro oxazolopirimidinonas sustituidas y uso de las mismas como moduladores de receptores metabotropicos de mglur
|
|
JP5204071B2
(ja)
|
2009-09-25 |
2013-06-05 |
パナソニック株式会社 |
電気かみそり
|
|
EP2496569A2
(en)
|
2009-11-02 |
2012-09-12 |
MSD Oss B.V. |
Heterocyclic derivatives
|
|
AU2011223898A1
(en)
|
2010-03-04 |
2012-09-13 |
Merck Sharp & Dohme Corp. |
Positive allosteric modulators of mGluR2
|
|
US8748632B2
(en)
|
2010-03-19 |
2014-06-10 |
Sanford-Burnham Medical Research Institute |
Positive allosteric modulators of group II mGluRs
|
|
US8664214B2
(en)
|
2010-03-30 |
2014-03-04 |
AbbVie Deutschland GmbH & Co. KG |
Small molecule potentiators of metabotropic glutamate receptors I
|
|
US8314120B2
(en)
|
2010-03-30 |
2012-11-20 |
Abbott Gmbh & Co. Kg |
Small molecule potentiators of metabotropic glutamate receptors
|
|
WO2011137046A1
(en)
|
2010-04-29 |
2011-11-03 |
Merck Sharp & Dohme Corp. |
Substituted 1,3-benzothiazol-2(3h)-ones and [1,3]thiazolo[5,4-b]pyridin-2(1h)-ones as positive allosteric modulators of mglur2
|
|
PH12012502074A1
(en)
|
2010-04-30 |
2013-02-04 |
Unilever Nv |
Composition
|
|
CA2795218A1
(en)
|
2010-04-30 |
2011-11-03 |
Helen Blade |
Polymorphs of a metabotropic glutamate receptor positive allosteric modulator
|
|
EP2579717A4
(en)
|
2010-06-09 |
2013-12-11 |
Merck Sharp & Dohme |
POSITIVE ALLOSTERIC MODULATORS OF MGLUR2
|
|
CN101893589B
(zh)
|
2010-06-29 |
2012-10-17 |
中国人民解放军第三0二医院 |
一种无菌检查方法及其使用的全封闭集菌安瓿培养器
|
|
EP2603079B1
(en)
|
2010-08-12 |
2018-09-19 |
Merck Sharp & Dohme Corp. |
Positive allosteric modulators of mglur2
|
|
CN103108871B
(zh)
|
2010-09-16 |
2014-09-10 |
诺华股份有限公司 |
17α-羟化酶/C17,20-裂合酶抑制剂
|
|
US8785481B2
(en)
|
2010-09-29 |
2014-07-22 |
Merck Sharp & Dohme Corp. |
Ether benzotriazole derivatives
|
|
PL2649069T3
(pl)
|
2010-11-08 |
2016-01-29 |
Janssen Pharmaceuticals Inc |
Pochodne 1,2,4-triazolo[4,3-a]pirydyny i ich zastosowanie jako dodatnich allosterycznych modulatorów receptorów mGluR2
|
|
JP5852665B2
(ja)
|
2010-11-08 |
2016-02-03 |
ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド |
１，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
|
|
JP5852666B2
(ja)
|
2010-11-08 |
2016-02-03 |
ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド |
１，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
|
|
AU2011328196A1
(en)
|
2010-11-08 |
2013-05-02 |
Janssen Pharmaceuticals, Inc. |
Radiolabelled mGluR2 PET ligands
|
|
CA2821972A1
(en)
*
|
2010-12-17 |
2012-06-21 |
Vanderbilt University |
Bicyclic triazole and pyrazole lactams as allosteric modulators of mglur5 receptors
|
|
GB201106817D0
(en)
|
2011-04-21 |
2011-06-01 |
Astex Therapeutics Ltd |
New compound
|
|
EP2705025A4
(en)
|
2011-05-03 |
2015-01-21 |
Merck Sharp & Dohme |
Hydroxymethyl biaryl benzotriazole derivatives
|
|
EP2705024B1
(en)
|
2011-05-03 |
2015-12-16 |
Merck Sharp & Dohme Corp. |
Alkyne benzotriazole derivatives
|
|
WO2012151136A1
(en)
|
2011-05-03 |
2012-11-08 |
Merck Sharp & Dohme Corp. |
Aminomethyl biaryl benzotriazole derivatives
|
|
WO2013012915A1
(en)
|
2011-07-19 |
2013-01-24 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
|
KR20140063605A
(ko)
|
2011-07-19 |
2014-05-27 |
인피니티 파마슈티칼스, 인코포레이티드 |
헤테로사이클릭 화합물 및 그의 용도
|
|
AU2012332895B2
(en)
|
2011-11-03 |
2015-12-17 |
Merck Sharp & Dohme Corp. |
Quinoline carboxamide and quinoline carbonitrile derivatives as mGluR2-negative allosteric modulators, compositions, and their use
|
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
|
US20130281397A1
(en)
|
2012-04-19 |
2013-10-24 |
Rvx Therapeutics Inc. |
Treatment of diseases by epigenetic regulation
|
|
JP6211797B2
(ja)
|
2012-05-14 |
2017-10-11 |
パナソニック株式会社 |
除臭剤を備えた除臭装置、および除臭装置を備えた冷蔵庫
|
|
EP2666775A1
(en)
|
2012-05-21 |
2013-11-27 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
AU2013277152A1
(en)
|
2012-06-20 |
2015-01-22 |
Vanderbilt University |
Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors
|
|
US20130345205A1
(en)
|
2012-06-20 |
2013-12-26 |
Vanderbilt University |
Substituted bicyclic aralkyl pyrazole lactam analogs as allosteric modulators of mglur5 receptors
|
|
US20130345204A1
(en)
|
2012-06-20 |
2013-12-26 |
Vanderbilt University |
Substituted bicyclic cycloalkyl pyrazole lactam analogs as allosteric modulators of mglur5 receptors
|
|
BR112015008297A2
(pt)
|
2012-10-23 |
2017-07-04 |
Hoffmann La Roche |
antagonistas de mglu2/3 para o tratamento de distúrbios autistas
|
|
US9191739B2
(en)
|
2013-03-25 |
2015-11-17 |
Bose Corporation |
Active reduction of harmonic noise from multiple rotating devices
|
|
JP6211798B2
(ja)
|
2013-05-17 |
2017-10-11 |
富士機械製造株式会社 |
基板上の異物検査方法および異物検査装置
|
|
JO3368B1
(ar)
|
2013-06-04 |
2019-03-13 |
Janssen Pharmaceutica Nv |
مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
|