[go: up one dir, main page]

SG10201912128SA - Treatment of diuretic resistance - Google Patents

Treatment of diuretic resistance

Info

Publication number
SG10201912128SA
SG10201912128SA SG10201912128SA SG10201912128SA SG10201912128SA SG 10201912128S A SG10201912128S A SG 10201912128SA SG 10201912128S A SG10201912128S A SG 10201912128SA SG 10201912128S A SG10201912128S A SG 10201912128SA SG 10201912128S A SG10201912128S A SG 10201912128SA
Authority
SG
Singapore
Prior art keywords
treatment
diuretic resistance
diuretic
resistance
Prior art date
Application number
SG10201912128SA
Other languages
English (en)
Inventor
Jeffrey Testani
Veena Rao
Rahul Kakkar
Chih-Hung Lo
Madhav N Devalaraja
Original Assignee
Univ Yale
Corvidia Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale, Corvidia Therapeutics Inc filed Critical Univ Yale
Publication of SG10201912128SA publication Critical patent/SG10201912128SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10201912128SA 2017-02-01 2018-02-01 Treatment of diuretic resistance SG10201912128SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762453257P 2017-02-01 2017-02-01

Publications (1)

Publication Number Publication Date
SG10201912128SA true SG10201912128SA (en) 2020-02-27

Family

ID=63040146

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201912128SA SG10201912128SA (en) 2017-02-01 2018-02-01 Treatment of diuretic resistance
SG11201906852XA SG11201906852XA (en) 2017-02-01 2018-02-01 Treatment of diuretic resistance

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201906852XA SG11201906852XA (en) 2017-02-01 2018-02-01 Treatment of diuretic resistance

Country Status (12)

Country Link
US (2) US11203636B2 (ja)
EP (1) EP3576790A4 (ja)
JP (3) JP7630906B2 (ja)
KR (2) KR20200012823A (ja)
CN (1) CN110913900A (ja)
AU (2) AU2018214554C1 (ja)
CA (1) CA3051865C (ja)
IL (2) IL268294B2 (ja)
MX (1) MX390722B (ja)
SG (2) SG10201912128SA (ja)
TW (3) TWI850514B (ja)
WO (1) WO2018144773A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3119498A1 (en) 2015-07-31 2017-02-09 Medimmune Limited Methods for treating hepcidin-mediated disorders
US11203636B2 (en) 2017-02-01 2021-12-21 Yale University Treatment of existing left ventricular heart failure
JP7395479B2 (ja) 2018-01-05 2023-12-11 ノヴォ ノルディスク アー/エス 免疫抑制なしにil-6媒介性炎症を処置する方法
MA55809A (fr) 2019-05-01 2022-03-09 Novo Nordisk As Formulation d'anticorps anti-il-6
JP2022537555A (ja) * 2019-06-20 2022-08-26 武田薬品工業株式会社 ウイルスベースの遺伝子療法による治療方法
AR122933A1 (es) 2020-07-10 2022-10-19 Novo Nordisk As Métodos para tratar la enfermedad cardiovascular
US20240050433A1 (en) * 2020-12-11 2024-02-15 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Application of jak inhibitor in kidney disease

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0399429A1 (en) 1989-05-22 1990-11-28 Toray Industries, Inc. Anti-human interleukin-6 monoclonal antibody
JP2881311B2 (ja) 1989-07-28 1999-04-12 味の素株式会社 抗ヒトbcdfモノクローナル抗体及びそれを用いたヒトbcdfの定量法
ZA943778B (en) 1993-05-31 1995-02-21 Chugai Seiyaku Kagushiki Kaish Reshaped human antibody to human interleukin-6
US5888510A (en) 1993-07-21 1999-03-30 Chugai Seiyaku Kabushiki Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
CA2168963C (en) * 1994-06-07 2007-01-16 Masayuki Miyata Drug for prevention and therapy of diseases caused by fibrinoid formation or thrombus formation in the lung and model animals of the diseases
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
JPH1066582A (ja) 1996-08-27 1998-03-10 Tosoh Corp Il−6のヘリックスd領域を認識する抗体の遺伝子断片等
EP1074268B1 (en) 1998-03-17 2008-01-16 Chugai Seiyaku Kabushiki Kaisha Preventives or remedies for inflammatory intestinal diseases containing il-6 receptor antagonist antibodies
US6395273B1 (en) 1998-06-10 2002-05-28 Promega Corporation Prevention and treatment of inflammatory bowel disease
US7163681B2 (en) 2000-08-07 2007-01-16 Centocor, Inc. Anti-integrin antibodies, compositions, methods and uses
WO2002036164A1 (fr) 2000-10-27 2002-05-10 Chugai Seiyaku Kabushiki Kaisha Agent abaissant le taux sanguin de vegf contenant un antagoniste de il-6 en tant que principe actif
DE60143544D1 (de) 2000-12-12 2011-01-05 Medimmune Llc Moleküle mit längeren halbwertszeiten, zusammensetzungen und deren verwendung
US7658921B2 (en) 2000-12-12 2010-02-09 Medimmune, Llc Molecules with extended half-lives, compositions and uses thereof
SK302004A3 (sk) 2001-06-28 2005-07-01 Pliva, D.D. Heterocyklické zlúčeniny a ich použitie ako inhibítory D-Ala-D-Ala ligázy
WO2004039826A1 (en) 2001-11-14 2004-05-13 Centocor, Inc. Anti-il-6 antibodies, compositions, methods and uses
EP1456347A4 (en) 2001-11-16 2006-08-02 Human Genome Sciences Inc ANTIBODIES BINDING TO BLYS ACCORDING TO AN IMMUNOSPECIFIC MODE
FR2833011B1 (fr) 2001-12-04 2004-10-29 Univ Claude Bernard Lyon Nouvelle proteine a activite inhibitrice de l'il-6
ES2263984T3 (es) 2002-06-28 2006-12-16 Domantis Limited Ligandos doble-especificos con una vida media serica aumentada.
US20060078533A1 (en) 2004-10-12 2006-04-13 Omoigui Osemwota S Method of prevention and treatment of aging and age-related disorders including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimer's disease and cancer
US20060275294A1 (en) 2002-08-22 2006-12-07 Omoigui Osemwota S Method of prevention and treatment of aging, age-related disorders and/or age-related manifestations including atherosclerosis, peripheral vascular disease, coronary artery disease, osteoporosis, arthritis, type 2 diabetes, dementia, alzheimers disease and cancer
KR100442281B1 (ko) 2002-08-26 2004-08-02 엘지전자 주식회사 홈 네트워크 시스템의 제어 방법
EP1536012A4 (en) 2002-08-30 2006-03-08 Chemo Sero Therapeut Res Inst HUMAN-TYPE ANTIHUMAN INTERLEUKIN-6 ANTIBODY ANTIBODY ANTIBODY FRAGMENT
JP2006516957A (ja) 2002-11-15 2006-07-13 セントカー・インコーポレーテツド Il−6アンタゴニストの抗血管形成用途
JP4869064B2 (ja) 2003-04-04 2012-02-01 ジェネンテック, インコーポレイテッド 高濃度抗体及びタンパク質製剤
JP4960096B2 (ja) 2003-09-22 2012-06-27 ペントラコール ゲゼルシャフト ミット ベシュレンクテル ハフツング Il−6の生物学的効果を減じる化合物の使用
JP2008505054A (ja) 2004-02-11 2008-02-21 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー Il−6アンタゴニストで骨関節炎を治療する方法
WO2006072954A2 (en) 2005-01-05 2006-07-13 Compugen Ltd. Novel il-6 polynucleotides encoding variant il-6 polypeptides and methods using same
PA8672101A1 (es) 2005-04-29 2006-12-07 Centocor Inc Anticuerpos anti-il-6, composiciones, métodos y usos
KR101414438B1 (ko) 2005-05-20 2014-07-10 아블린쓰 엔.브이. 폰 빌레브란트 인자에 대한 단일 도메인 vhh 항체
US8163881B2 (en) 2005-05-31 2012-04-24 The Board Of Regents Of The University Of Texas System Immunoglobulin molecules with improved characteristics
AR057582A1 (es) 2005-11-15 2007-12-05 Nat Hospital Organization Agentes para suprimir la induccion de linfocitos t citotoxicos
EP1967209B1 (en) 2005-11-25 2012-06-06 Keio University Therapeutic agent for prostate cancer
JP5183484B2 (ja) 2005-12-09 2013-04-17 ユセベ ファルマ ソシエテ アノニム ヒトil−6に対して特異性を有する抗体分子
US9084777B2 (en) 2005-12-28 2015-07-21 Chugai Seiyaku Kabushiki Kaisha Stabilized antibody-containing formulations
BRPI0620797A2 (pt) 2005-12-30 2011-11-22 Merck Patent Ges Mit Beschonkter Haftung anticorpos anti-il-6 que previnem a ligação de il-6 complexado com il-6ralfa a gp130
WO2007104529A2 (en) 2006-03-13 2007-09-20 Ablynx N.V. Amino acid sequences directed against il-6 and polypeptides comprising the same for the treatment of diseases and disorders associated with il-6-mediated signalling
US7504106B2 (en) * 2006-03-14 2009-03-17 Boris Skurkovich Method and composition for treatment of renal failure with antibodies and their equivalents as partial or complete replacement for dialysis
CA2657763C (en) 2006-08-03 2016-05-31 Vaccinex Inc. Anti-il-6 monoclonal antibodies and uses thereof
JP2010507624A (ja) 2006-10-27 2010-03-11 アブリンクス エン.ヴェー. ポリペプチド及びタンパク質の鼻内送達
ES2433380T3 (es) 2006-11-30 2013-12-10 Medimmune Limited Anticuerpos específicos para el complejo de interleucina 6 y el receptor de interleucina 6
TW200831528A (en) 2006-11-30 2008-08-01 Astrazeneca Ab Compounds
JP4966647B2 (ja) 2006-12-27 2012-07-04 矢崎総業株式会社 電気接続箱のシール構造
US20090060906A1 (en) 2007-01-09 2009-03-05 Wyeth Anti-IL-13 antibody formulations and uses thereof
CA2685465C (en) 2007-05-07 2020-02-25 Medimmune, Llc Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
HUE032563T2 (en) 2007-05-21 2017-09-28 Alderbio Holdings Llc Antibodies to IL-6 and their use
US8404235B2 (en) 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8062864B2 (en) 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
US20090238825A1 (en) 2007-05-21 2009-09-24 Kovacevich Brian R Novel rabbit antibody humanization methods and humanized rabbit antibodies
KR20170036814A (ko) 2007-05-21 2017-04-03 앨더바이오 홀딩스 엘엘씨 신규한 래빗 항체 인간화 방법 및 인간화된 래빗 항체
EP2170393A4 (en) 2007-06-19 2013-01-23 Univ Johns Hopkins ANTITROMOMBOTIC AGENTS AND METHOD OF USE THEREOF
US20110008329A1 (en) 2007-06-26 2011-01-13 Medlmmune, Llc Methods of Treating RSV Infections And Related Conditions
US9884899B2 (en) 2007-07-06 2018-02-06 Promedior, Inc. Methods for treating fibrosis using CRP antagonists
CA2734577A1 (en) 2007-08-16 2009-02-26 Carnegie Mellon University Inflammation-regulating compositions and methods
US20100203009A1 (en) 2007-10-02 2010-08-12 The Uab Research Foundation Pathway for Th-17 Cell Development and Methods Utilizing Same
PE20091174A1 (es) 2007-12-27 2009-08-03 Chugai Pharmaceutical Co Ltd Formulacion liquida con contenido de alta concentracion de anticuerpo
AU2009246430B2 (en) 2008-05-13 2015-07-02 Novimmune S.A. Anti-IL-6/IL-6R antibodies and methods of use thereof
US8277804B2 (en) 2008-05-21 2012-10-02 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8188235B2 (en) 2008-06-18 2012-05-29 Pfizer Inc. Antibodies to IL-6 and their uses
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
NZ602166A (en) 2008-11-25 2014-02-28 Alder Biopharmaceuticals Inc Antibodies to il-6 and use thereof
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
AU2010208125B2 (en) 2009-01-29 2015-02-12 Medimmune, Llc Human anti-IL-6 antibodies with extended in vivo half-life and their use in treatment of oncology, autoimmune diseases and inflammatory diseases
US9468676B2 (en) 2009-11-24 2016-10-18 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
JO3417B1 (ar) 2010-01-08 2019-10-20 Regeneron Pharma الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
US20130224109A1 (en) * 2010-07-20 2013-08-29 Beth Israel Deaconess Medical Center, Inc. Compositions and methods featuring il-6 and il-21 antagonists
NZ609557A (en) 2010-10-06 2014-12-24 Regeneron Pharma Stabilized formulations containing anti-interleukin-4 receptor (il-4r) antibodies
US20120189621A1 (en) * 2011-01-21 2012-07-26 Yann Dean Combination Therapies and Methods Using Anti-CD3 Modulating Agents and Anti-IL-6 Antagonists
MX342810B (es) 2011-03-03 2016-10-13 Apexigen Inc Anticuerpos del receptor anti-interleucina-6 (anti-il-6) y sus metodos de uso.
WO2013175276A1 (en) 2012-05-23 2013-11-28 Argen-X B.V Il-6 binding molecules
KR20160009008A (ko) 2012-10-22 2016-01-25 스텔스 바이오테라퓨틱스 코포레이션 심부전과 관련된 위험 및 이와 관련된 인자를 감소시키는 방법
JP2015536934A (ja) 2012-10-25 2015-12-24 メディミューン,エルエルシー 安定した低粘度の抗体製剤
MX2015005831A (es) 2012-11-08 2015-09-24 Eleven Biotherapeutics Inc Antagonistas de il-6 y usos de los mismos.
BR112015010566A2 (pt) 2012-11-08 2017-07-11 Clearside Biomedical Inc métodos e dispositivos para o tratamento de doenças oculares em indivíduos humanos
JP2016064985A (ja) * 2013-02-01 2016-04-28 国立大学法人大阪大学 拡張性心不全を治療または診断するための組成物およびその利用
ES2695166T3 (es) 2013-03-15 2019-01-02 Intrinsic Lifesciences Llc Anticuerpos antihepcidina y usos de los mismos
AU2014314053C1 (en) 2013-08-30 2023-11-02 Takeda Pharmaceutical Company Limited Antibodies neutralizing GM-CSF for use in the treatment of rheumatoid arthritis or as analgesics
US20160130340A1 (en) 2013-10-07 2016-05-12 Alderbio Holdings Llc Dosing regimens using anti-il-6 antibodies for the treatment of rheumatoid and psoriatic arthritis
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US8945560B1 (en) 2014-07-15 2015-02-03 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US9139648B1 (en) 2014-07-15 2015-09-22 Kymab Limited Precision medicine by targeting human NAV1.9 variants for treatment of pain
UY36449A (es) 2014-12-19 2016-07-29 Novartis Ag Composiciones y métodos para anticuerpos dirigidos a bmp6
CA3119498A1 (en) 2015-07-31 2017-02-09 Medimmune Limited Methods for treating hepcidin-mediated disorders
US11203636B2 (en) 2017-02-01 2021-12-21 Yale University Treatment of existing left ventricular heart failure
JP7395479B2 (ja) 2018-01-05 2023-12-11 ノヴォ ノルディスク アー/エス 免疫抑制なしにil-6媒介性炎症を処置する方法

Also Published As

Publication number Publication date
SG11201906852XA (en) 2019-08-27
KR20250029283A (ko) 2025-03-04
TWI716668B (zh) 2021-01-21
EP3576790A4 (en) 2020-12-23
CA3051865C (en) 2023-01-17
EP3576790A1 (en) 2019-12-11
IL268294B1 (en) 2023-03-01
AU2018214554A1 (en) 2019-09-19
JP7630906B2 (ja) 2025-02-18
IL268294A (en) 2019-09-26
US20220195033A1 (en) 2022-06-23
JP2020506190A (ja) 2020-02-27
WO2018144773A1 (en) 2018-08-09
IL281274A (en) 2021-04-29
TW202130366A (zh) 2021-08-16
US11203636B2 (en) 2021-12-21
TW202444416A (zh) 2024-11-16
CN110913900A (zh) 2020-03-24
MX390722B (es) 2025-03-21
IL268294B2 (en) 2023-07-01
JP2023002563A (ja) 2023-01-10
AU2018214554C1 (en) 2022-12-15
US20200079846A1 (en) 2020-03-12
JP2024164113A (ja) 2024-11-26
TW201832780A (zh) 2018-09-16
CA3051865A1 (en) 2018-08-09
AU2022221557A1 (en) 2022-11-24
KR20200012823A (ko) 2020-02-05
AU2018214554B2 (en) 2022-06-02
TWI850514B (zh) 2024-08-01

Similar Documents

Publication Publication Date Title
ZA202006746B (en) Methods of treatment
IL281274A (en) Methods for treating diuretic resistance
GB201608885D0 (en) Treatment
GB201818605D0 (en) Nivel use
IL269409A (en) Combinations of chk1- and wee1 - inhibitors
GB201502137D0 (en) Treatment
GB201522243D0 (en) Treatment
IL272738A (en) treatment regimens
IL254825A0 (en) Methods of treatment with Tesalisib
SG11202005850VA (en) Methods of treatment of hypertrigl yceridemia
GB201508841D0 (en) Treatment
GB201500534D0 (en) Sexual stimulator
GB201700526D0 (en) Therapeutic use
GB201510481D0 (en) Artificial heart
PL2875832T3 (pl) Pasta implantowalna i jej zastosowanie
GB201707846D0 (en) Use
HK40019119A (en) Treatment of diuretic resistance
GB201503008D0 (en) Treatment
GB2558788B (en) New therapeutic uses
GB201718985D0 (en) Treatment
GB201713650D0 (en) Treatment
GB201720107D0 (en) Human Wings
GB201706955D0 (en) Treatment
GB201721386D0 (en) Chrondogy of time-wave
GB201711677D0 (en) Combination treatment