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SE9600086D0 - New manufacturing process - Google Patents

New manufacturing process

Info

Publication number
SE9600086D0
SE9600086D0 SE9600086A SE9600086A SE9600086D0 SE 9600086 D0 SE9600086 D0 SE 9600086D0 SE 9600086 A SE9600086 A SE 9600086A SE 9600086 A SE9600086 A SE 9600086A SE 9600086 D0 SE9600086 D0 SE 9600086D0
Authority
SE
Sweden
Prior art keywords
pct
manufacturing process
new manufacturing
sec
date
Prior art date
Application number
SE9600086A
Other languages
English (en)
Swedish (sv)
Inventor
Anders Gustavsson
Aake Kaellstroem
Sven Palmer
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9600086A priority Critical patent/SE9600086D0/xx
Publication of SE9600086D0 publication Critical patent/SE9600086D0/xx
Priority to PT96944714T priority patent/PT874822E/pt
Priority to KR1019980705100A priority patent/KR100488384B1/ko
Priority to ES96944714T priority patent/ES2206617T3/es
Priority to AT96944714T priority patent/ATE249436T1/de
Priority to DE69629942T priority patent/DE69629942T2/de
Priority to NZ325967A priority patent/NZ325967A/xx
Priority to PL96327946A priority patent/PL188308B1/pl
Priority to SK878-98A priority patent/SK281989B6/sk
Priority to EE9800201A priority patent/EE03438B1/xx
Priority to EP96944714A priority patent/EP0874822B1/en
Priority to BR9612457A priority patent/BR9612457A/pt
Priority to RU98112386/04A priority patent/RU2171251C2/ru
Priority to PCT/SE1996/001649 priority patent/WO1997025313A1/en
Priority to TR1998/01283T priority patent/TR199801283T2/xx
Priority to JP52512297A priority patent/JP4587497B2/ja
Priority to DK96944714T priority patent/DK0874822T3/da
Priority to CN96199573A priority patent/CN1105104C/zh
Priority to US08/750,933 priority patent/US5942624A/en
Priority to HU9901392A priority patent/HU227384B1/hu
Priority to SI9630642T priority patent/SI0874822T1/xx
Priority to CZ19982180A priority patent/CZ291063B6/cs
Priority to UA98063019A priority patent/UA44914C2/uk
Priority to IL12519496A priority patent/IL125194A/en
Priority to CA002240201A priority patent/CA2240201C/en
Priority to AU13230/97A priority patent/AU706989B2/en
Priority to ZA9610937A priority patent/ZA9610937B/xx
Priority to TW085116296A priority patent/TW343194B/zh
Priority to ARP970100008A priority patent/AR005342A1/es
Priority to EG1797A priority patent/EG24197A/xx
Priority to MYPI97000093A priority patent/MY116842A/en
Priority to IS4779A priority patent/IS1826B/is
Priority to NO19983166A priority patent/NO310233B1/no
Priority to HK99100002A priority patent/HK1014941A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • General Factory Administration (AREA)
  • Catalysts (AREA)
SE9600086A 1996-01-10 1996-01-10 New manufacturing process SE9600086D0 (sv)

Priority Applications (34)

Application Number Priority Date Filing Date Title
SE9600086A SE9600086D0 (sv) 1996-01-10 1996-01-10 New manufacturing process
AU13230/97A AU706989B2 (en) 1996-01-10 1996-12-13 New manufacturing process
DK96944714T DK0874822T3 (da) 1996-01-10 1996-12-13 Ny fremgangsmåde til fremstilling
CN96199573A CN1105104C (zh) 1996-01-10 1996-12-13 新的制备方法
ES96944714T ES2206617T3 (es) 1996-01-10 1996-12-13 Nuevo procedimiento de fabricacion.
AT96944714T ATE249436T1 (de) 1996-01-10 1996-12-13 Herstellungsverfahren
DE69629942T DE69629942T2 (de) 1996-01-10 1996-12-13 Herstellungsverfahren
NZ325967A NZ325967A (en) 1996-01-10 1996-12-13 New manufacturing process for felodipine by reacting dichlorobenzlidene and ethyl 3-aminocrtonate using alcohol as a solvent
PL96327946A PL188308B1 (pl) 1996-01-10 1996-12-13 Sposób wytwarzania estru etylowo-metylowego kwasu4-(2,3-dichlorofenylo)-1,4-dihydro-2,6-dimetylo-3,5-pirydynodikarboksylowego
SK878-98A SK281989B6 (sk) 1996-01-10 1996-12-13 Spôsob výroby felodipínu
EE9800201A EE03438B1 (et) 1996-01-10 1996-12-13 Felodipiini valmistamise protsess
EP96944714A EP0874822B1 (en) 1996-01-10 1996-12-13 New manufacturing process
BR9612457A BR9612457A (pt) 1996-01-10 1996-12-13 Processo para a fabricação de felodipina
RU98112386/04A RU2171251C2 (ru) 1996-01-10 1996-12-13 Способ производства фелодипина
PCT/SE1996/001649 WO1997025313A1 (en) 1996-01-10 1996-12-13 New manufacturing process
TR1998/01283T TR199801283T2 (xx) 1996-01-10 1996-12-13 Yeni imalat prosesi.
JP52512297A JP4587497B2 (ja) 1996-01-10 1996-12-13 新しい製造方法
PT96944714T PT874822E (pt) 1996-01-10 1996-12-13 Novo processo de producao
HU9901392A HU227384B1 (en) 1996-01-10 1996-12-13 Process for producing felodipine
KR1019980705100A KR100488384B1 (ko) 1996-01-10 1996-12-13 신규한제조방법
US08/750,933 US5942624A (en) 1996-01-10 1996-12-13 Manufacturing process for felodipine
SI9630642T SI0874822T1 (en) 1996-01-10 1996-12-13 New manufacturing process
CZ19982180A CZ291063B6 (cs) 1996-01-10 1996-12-13 Způsob přípravy felodipinu
UA98063019A UA44914C2 (uk) 1996-01-10 1996-12-13 Спосіб одержання фелодипіну та спосіб одержання фелодипіну у формі фармацевтичного препарату
IL12519496A IL125194A (en) 1996-01-10 1996-12-13 Process for the production of flodipine
CA002240201A CA2240201C (en) 1996-01-10 1996-12-13 Process for the preparation of felodipine
TW085116296A TW343194B (en) 1996-01-10 1996-12-30 Improved method for the manufacture of felodipine
ZA9610937A ZA9610937B (en) 1996-01-10 1996-12-30 New manufacturing process
ARP970100008A AR005342A1 (es) 1996-01-10 1997-01-02 Metodo para la manufactura de felodipina
EG1797A EG24197A (en) 1996-01-10 1997-01-07 New manufacturing process
MYPI97000093A MY116842A (en) 1996-01-10 1997-01-09 Manufacturing process for felopipine
IS4779A IS1826B (is) 1996-01-10 1998-06-19 Aðferð til að framleiða felódipín og aðferð til að framleiða lyfjablöndu
NO19983166A NO310233B1 (no) 1996-01-10 1998-07-09 Fremgangsmåte for fremstilling av felodipin, og fremgangsmåte for fremstilling av et farmasöytisk preparat
HK99100002A HK1014941A1 (en) 1996-01-10 1999-01-04 New manufacturing process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9600086A SE9600086D0 (sv) 1996-01-10 1996-01-10 New manufacturing process

Publications (1)

Publication Number Publication Date
SE9600086D0 true SE9600086D0 (sv) 1996-01-10

Family

ID=20400982

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9600086A SE9600086D0 (sv) 1996-01-10 1996-01-10 New manufacturing process

Country Status (34)

Country Link
US (1) US5942624A (es)
EP (1) EP0874822B1 (es)
JP (1) JP4587497B2 (es)
KR (1) KR100488384B1 (es)
CN (1) CN1105104C (es)
AR (1) AR005342A1 (es)
AT (1) ATE249436T1 (es)
AU (1) AU706989B2 (es)
BR (1) BR9612457A (es)
CA (1) CA2240201C (es)
CZ (1) CZ291063B6 (es)
DE (1) DE69629942T2 (es)
DK (1) DK0874822T3 (es)
EE (1) EE03438B1 (es)
EG (1) EG24197A (es)
ES (1) ES2206617T3 (es)
HK (1) HK1014941A1 (es)
HU (1) HU227384B1 (es)
IL (1) IL125194A (es)
IS (1) IS1826B (es)
MY (1) MY116842A (es)
NO (1) NO310233B1 (es)
NZ (1) NZ325967A (es)
PL (1) PL188308B1 (es)
PT (1) PT874822E (es)
RU (1) RU2171251C2 (es)
SE (1) SE9600086D0 (es)
SI (1) SI0874822T1 (es)
SK (1) SK281989B6 (es)
TR (1) TR199801283T2 (es)
TW (1) TW343194B (es)
UA (1) UA44914C2 (es)
WO (1) WO1997025313A1 (es)
ZA (1) ZA9610937B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
KR101369207B1 (ko) 2007-04-11 2014-03-04 한국과학기술원 (ｓ)-(-)-펠로디핀의 제조방법
WO2010027113A2 (en) * 2008-09-04 2010-03-11 Ahn-Gook Pharmaceutical Co., Ltd Process for preparing (s)-(-)-felodipine
CN101613280B (zh) * 2009-05-13 2012-10-17 合肥立方制药股份有限公司 非洛地平合成中间体2,3-二氯亚苄基乙酰乙酸甲酯的制备方法
CN101735042B (zh) * 2009-12-15 2013-10-09 浙江大学 2-烷基-4,4-二芳基反-2-丁烯酸乙酯的合成方法
WO2012123966A1 (en) 2011-03-04 2012-09-20 Arch Pharmalabs Limited Process for the preparation of 4 -substituted -1, 4-dihydropyridines
CN102304079B (zh) * 2011-09-29 2013-09-25 合肥立方制药股份有限公司 一种非洛地平环合反应液直接水析纯化方法
CN103373956B (zh) * 2012-04-23 2015-07-01 黑龙江省格润药业有限责任公司 一种制备丁酸氯维地平的方法
CN104557679A (zh) * 2013-10-23 2015-04-29 丹阳恒安化学科技研究所有限公司 一种西尼地平的合成方法
CN108840819B (zh) * 2018-04-02 2021-07-30 常州瑞明药业有限公司 一种非洛地平的制备方法
CN115201379B (zh) * 2022-07-26 2023-10-20 常州瑞明药业有限公司 非洛地平中基因毒性杂质的检测方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
US5310917A (en) * 1991-09-13 1994-05-10 Merck & Co., Inc. Process for the preparation of 4-substituted-1,4-dihydropydrines

Also Published As

Publication number Publication date
NO983166L (no) 1998-07-09
PL327946A1 (en) 1999-01-04
NO310233B1 (no) 2001-06-11
SK87898A3 (en) 1998-12-02
ES2206617T3 (es) 2004-05-16
HUP9901392A3 (en) 1999-11-29
JP2000503647A (ja) 2000-03-28
IS4779A (is) 1998-06-19
US5942624A (en) 1999-08-24
IL125194A (en) 2002-09-12
WO1997025313A1 (en) 1997-07-17
EE9800201A (et) 1998-12-15
CZ218098A3 (cs) 1998-10-14
DE69629942D1 (de) 2003-10-16
ATE249436T1 (de) 2003-09-15
EP0874822A1 (en) 1998-11-04
AU706989B2 (en) 1999-07-01
HK1014941A1 (en) 1999-10-08
TR199801283T2 (xx) 1998-10-21
PL188308B1 (pl) 2005-01-31
KR100488384B1 (ko) 2006-03-23
SK281989B6 (sk) 2001-09-11
IL125194A0 (en) 1999-03-12
TW343194B (en) 1998-10-21
EE03438B1 (et) 2001-06-15
CA2240201C (en) 2006-08-29
AU1323097A (en) 1997-08-01
CN1105104C (zh) 2003-04-09
MY116842A (en) 2004-04-30
SI0874822T1 (en) 2004-02-29
CN1207726A (zh) 1999-02-10
AR005342A1 (es) 1999-04-28
BR9612457A (pt) 1999-07-13
DK0874822T3 (da) 2003-12-08
HU227384B1 (en) 2011-05-30
CZ291063B6 (cs) 2002-12-11
EG24197A (en) 2008-10-14
KR19990076972A (ko) 1999-10-25
PT874822E (pt) 2004-02-27
IS1826B (is) 2002-10-01
ZA9610937B (en) 1997-07-10
RU2171251C2 (ru) 2001-07-27
JP4587497B2 (ja) 2010-11-24
DE69629942T2 (de) 2004-07-15
NZ325967A (en) 2000-01-28
EP0874822B1 (en) 2003-09-10
CA2240201A1 (en) 1997-07-17
HUP9901392A2 (hu) 1999-08-30
UA44914C2 (uk) 2002-03-15

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