SE8600632D0 - Novel pharmaceutical composition - Google Patents
Novel pharmaceutical compositionInfo
- Publication number
- SE8600632D0 SE8600632D0 SE8600632A SE8600632A SE8600632D0 SE 8600632 D0 SE8600632 D0 SE 8600632D0 SE 8600632 A SE8600632 A SE 8600632A SE 8600632 A SE8600632 A SE 8600632A SE 8600632 D0 SE8600632 D0 SE 8600632D0
- Authority
- SE
- Sweden
- Prior art keywords
- pharmaceutical composition
- novel pharmaceutical
- pregnanolone
- composition
- claving
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- AURFZBICLPNKBZ-YZRLXODZSA-N 3alpha-hydroxy-5beta-pregnan-20-one Chemical compound C([C@H]1CC2)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](C(=O)C)[C@@]2(C)CC1 AURFZBICLPNKBZ-YZRLXODZSA-N 0.000 abstract 2
- AURFZBICLPNKBZ-UHFFFAOYSA-N Pregnanolone Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(=O)C)C1(C)CC2 AURFZBICLPNKBZ-UHFFFAOYSA-N 0.000 abstract 2
- 229950007402 eltanolone Drugs 0.000 abstract 2
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000007764 o/w emulsion Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Anesthesiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600632A SE8600632D0 (sv) | 1986-02-13 | 1986-02-13 | Novel pharmaceutical composition |
AT87850029T ATE64526T1 (de) | 1986-02-13 | 1987-01-29 | Zubereitung von pregnanolol in einer stabilen oel- in-wasser-emulsion. |
DE8787850029T DE3770830D1 (de) | 1986-02-13 | 1987-01-29 | Zubereitung von pregnanolol in einer stabilen oel-in-wasser-emulsion. |
EP87850029A EP0233849B1 (de) | 1986-02-13 | 1987-01-29 | Zubereitung von Pregnanolol in einer stabilen Öl-in-Wasser-Emulsion |
ES198787850029T ES2037742T3 (es) | 1986-02-13 | 1987-01-29 | Procedimiento de obtencion de una composicion para administracion intravenosa. |
DK198700621A DK175504B1 (da) | 1986-02-13 | 1987-02-06 | Farmaceutisk præparat indeholdende 3alfa-hydroxy-5beta-pregnan-20-on og fremstilling deraf |
CA000529609A CA1301651C (en) | 1986-02-13 | 1987-02-12 | Pharmaceutical composition containing pregnanolone |
JP62028395A JPH0788305B2 (ja) | 1986-02-13 | 1987-02-12 | 静脈内投与用組成物およびその製法 |
FI870589A FI88676C (fi) | 1986-02-13 | 1987-02-12 | Foerfarande foer framstaellning av en komposition foer intravenoes administrering av pregnanolon |
NO870560A NO175040B (no) | 1986-02-13 | 1987-02-12 | Fremgangsmåte for fremstilling av et preparat for intravenös administrering av 3 |
US07/316,576 US5028600A (en) | 1986-02-13 | 1989-02-28 | Novel pharmaceutical composition |
GR91400996T GR3002299T3 (en) | 1986-02-13 | 1991-07-11 | Composition of pregnanolole comprising a stable oil-in-water emulsion |
SG1028/92A SG102892G (en) | 1986-02-13 | 1992-10-07 | Composition of pregnanolole comprising a stable oil-in-water emulsion |
HK832/93A HK83293A (en) | 1986-02-13 | 1993-08-12 | Composition of pregnanolole comprising a stable oil-in-water emulsion |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8600632A SE8600632D0 (sv) | 1986-02-13 | 1986-02-13 | Novel pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
SE8600632D0 true SE8600632D0 (sv) | 1986-02-13 |
Family
ID=20363448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8600632A SE8600632D0 (sv) | 1986-02-13 | 1986-02-13 | Novel pharmaceutical composition |
Country Status (14)
Country | Link |
---|---|
US (1) | US5028600A (de) |
EP (1) | EP0233849B1 (de) |
JP (1) | JPH0788305B2 (de) |
AT (1) | ATE64526T1 (de) |
CA (1) | CA1301651C (de) |
DE (1) | DE3770830D1 (de) |
DK (1) | DK175504B1 (de) |
ES (1) | ES2037742T3 (de) |
FI (1) | FI88676C (de) |
GR (1) | GR3002299T3 (de) |
HK (1) | HK83293A (de) |
NO (1) | NO175040B (de) |
SE (1) | SE8600632D0 (de) |
SG (1) | SG102892G (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9302295D0 (sv) * | 1993-07-02 | 1993-07-02 | Kabi Pharmacia Ab | New pharmaceutical composition |
US5616330A (en) * | 1994-07-19 | 1997-04-01 | Hemagen/Pfc | Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same |
AU8779898A (en) * | 1997-08-11 | 1999-03-01 | Weider Nutrition International, Inc. | Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors |
WO2000010531A1 (en) | 1998-08-19 | 2000-03-02 | Rtp Pharma Inc. | Injectable aqueous dispersions of propofol |
US20020155161A1 (en) * | 2000-12-29 | 2002-10-24 | Deckelbaum Richard J. | Use of IV emulsions with different triglyceride composition, particle size and apolipoprotein E for targeted tissue delivery of hydrophobic compounds |
MXPA04012756A (es) * | 2002-07-02 | 2005-03-23 | Altana Pharma Ag | Suspension acuosa esteril que contiene ciclesonida. |
PE20050941A1 (es) * | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
EA200700440A1 (ru) * | 2004-09-13 | 2008-02-28 | Бхарат Сирумс Энд Вэксинс Лтд. | Композиции стабильных эмульсий для внутривенного введения, имеющие защитную эффективность |
EP2663326B2 (de) * | 2011-01-14 | 2021-09-29 | Vivacelle Bio, Inc. | Verfahren und zusammensetzungen zur behandlung von leiden in zusammenhang mit mangelnder blutversorgung, schocks und verletzungen |
US10478505B2 (en) | 2011-09-23 | 2019-11-19 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
CA2862076C (en) | 2012-01-23 | 2020-04-21 | Sage Therapeutics, Inc. | Neuroactive steroid formulations and methods of treating cns disorders |
US20140050789A1 (en) | 2012-08-13 | 2014-02-20 | The Regents Of The University Of California | Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids |
IL275725B (en) | 2012-08-21 | 2022-08-01 | Sage Therapeutics Inc | Methods of treating epilepsy or status epilepticus |
DK2925327T3 (da) | 2012-11-30 | 2024-03-25 | Univ California | Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression |
JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
TWI798173B (zh) | 2016-03-08 | 2023-04-11 | 美商賽吉醫療公司 | 神經活性類固醇,其組合物及用途 |
WO2020123551A1 (en) * | 2018-12-10 | 2020-06-18 | Halo Science LLC | Stable formulations of anesthetics and associated dosage forms |
EP4017498A4 (de) * | 2019-08-19 | 2022-11-09 | Arizona Board of Regents on behalf of the University of Arizona | Topische neurosteroidformulierungen |
US11969434B1 (en) | 2022-08-29 | 2024-04-30 | Lipocine Inc. | Oral allopregnanolone compositions and methods of use |
CN114344309B (zh) * | 2021-12-30 | 2024-02-06 | 南京迈诺威医药科技有限公司 | 一种别孕烷醇酮衍生物自乳化制剂及其制备方法 |
US12186327B2 (en) | 2022-08-29 | 2025-01-07 | Lipocine Inc. | Oral allopregnanolone compositions and methods of use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1215702B (de) * | 1962-07-03 | 1966-05-05 | Merck Ag E | Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen |
CA895860A (en) * | 1969-11-05 | 1972-03-21 | Kruger Gunther | PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE |
US3917830A (en) * | 1970-12-17 | 1975-11-04 | Glaxo Lab Ltd | Steroidal anaesthetic composition for intraveneous injection |
US3900561A (en) * | 1970-12-17 | 1975-08-19 | Glaxo Lab Ltd | Pharmaceutical compositions |
US4168308A (en) * | 1976-03-12 | 1979-09-18 | Apoteksvarucentralen Vitrum Ab | Composition for enhancing the administration of pharmacologically active agents |
JPS609726B2 (ja) * | 1980-05-15 | 1985-03-12 | 株式会社 ミドリ十字 | ステロイド製剤 |
JPS5716818A (en) * | 1981-04-25 | 1982-01-28 | Green Cross Corp:The | Steroid fatty emulsion |
JPS60258110A (ja) * | 1984-06-05 | 1985-12-20 | Daigo Eiyou Kagaku Kk | 静脈注射可能なプロゲステロン乳化注射液 |
-
1986
- 1986-02-13 SE SE8600632A patent/SE8600632D0/xx unknown
-
1987
- 1987-01-29 ES ES198787850029T patent/ES2037742T3/es not_active Expired - Lifetime
- 1987-01-29 DE DE8787850029T patent/DE3770830D1/de not_active Expired - Fee Related
- 1987-01-29 EP EP87850029A patent/EP0233849B1/de not_active Expired - Lifetime
- 1987-01-29 AT AT87850029T patent/ATE64526T1/de not_active IP Right Cessation
- 1987-02-06 DK DK198700621A patent/DK175504B1/da not_active IP Right Cessation
- 1987-02-12 JP JP62028395A patent/JPH0788305B2/ja not_active Expired - Fee Related
- 1987-02-12 FI FI870589A patent/FI88676C/fi not_active IP Right Cessation
- 1987-02-12 CA CA000529609A patent/CA1301651C/en not_active Expired - Fee Related
- 1987-02-12 NO NO870560A patent/NO175040B/no not_active IP Right Cessation
-
1989
- 1989-02-28 US US07/316,576 patent/US5028600A/en not_active Expired - Lifetime
-
1991
- 1991-07-11 GR GR91400996T patent/GR3002299T3/el unknown
-
1992
- 1992-10-07 SG SG1028/92A patent/SG102892G/en unknown
-
1993
- 1993-08-12 HK HK832/93A patent/HK83293A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ES2037742T3 (es) | 1993-07-01 |
DE3770830D1 (de) | 1991-07-25 |
NO870560L (no) | 1987-08-14 |
NO175040B (no) | 1994-05-16 |
FI88676B (fi) | 1993-03-15 |
FI870589L (fi) | 1987-08-14 |
FI88676C (fi) | 1993-06-28 |
EP0233849A1 (de) | 1987-08-26 |
GR3002299T3 (en) | 1992-12-30 |
JPS62192322A (ja) | 1987-08-22 |
JPH0788305B2 (ja) | 1995-09-27 |
DK62187D0 (da) | 1987-02-06 |
SG102892G (en) | 1992-12-04 |
FI870589A0 (fi) | 1987-02-12 |
NO175040C (de) | 1994-08-24 |
EP0233849B1 (de) | 1991-06-19 |
NO870560D0 (no) | 1987-02-12 |
DK62187A (da) | 1987-08-14 |
DK175504B1 (da) | 2004-11-15 |
ATE64526T1 (de) | 1991-07-15 |
HK83293A (en) | 1993-08-20 |
CA1301651C (en) | 1992-05-26 |
US5028600A (en) | 1991-07-02 |
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