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NO175040B - Fremgangsmåte for fremstilling av et preparat for intravenös administrering av 3 - Google Patents

Fremgangsmåte for fremstilling av et preparat for intravenös administrering av 3 Download PDF

Info

Publication number
NO175040B
NO175040B NO870560A NO870560A NO175040B NO 175040 B NO175040 B NO 175040B NO 870560 A NO870560 A NO 870560A NO 870560 A NO870560 A NO 870560A NO 175040 B NO175040 B NO 175040B
Authority
NO
Norway
Prior art keywords
oil
pregnanolone
amount
preparation
final composition
Prior art date
Application number
NO870560A
Other languages
English (en)
Norwegian (no)
Other versions
NO870560L (no
NO175040C (de
NO870560D0 (no
Inventor
Roland Ingolf Jeppsson
Original Assignee
Kabi Pharmacia Ab
Kabivitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab, Kabivitrum Ab filed Critical Kabi Pharmacia Ab
Publication of NO870560D0 publication Critical patent/NO870560D0/no
Publication of NO870560L publication Critical patent/NO870560L/no
Publication of NO175040B publication Critical patent/NO175040B/no
Publication of NO175040C publication Critical patent/NO175040C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO870560A 1986-02-13 1987-02-12 Fremgangsmåte for fremstilling av et preparat for intravenös administrering av 3 NO175040B (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8600632A SE8600632D0 (sv) 1986-02-13 1986-02-13 Novel pharmaceutical composition

Publications (4)

Publication Number Publication Date
NO870560D0 NO870560D0 (no) 1987-02-12
NO870560L NO870560L (no) 1987-08-14
NO175040B true NO175040B (no) 1994-05-16
NO175040C NO175040C (de) 1994-08-24

Family

ID=20363448

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870560A NO175040B (no) 1986-02-13 1987-02-12 Fremgangsmåte for fremstilling av et preparat for intravenös administrering av 3

Country Status (14)

Country Link
US (1) US5028600A (de)
EP (1) EP0233849B1 (de)
JP (1) JPH0788305B2 (de)
AT (1) ATE64526T1 (de)
CA (1) CA1301651C (de)
DE (1) DE3770830D1 (de)
DK (1) DK175504B1 (de)
ES (1) ES2037742T3 (de)
FI (1) FI88676C (de)
GR (1) GR3002299T3 (de)
HK (1) HK83293A (de)
NO (1) NO175040B (de)
SE (1) SE8600632D0 (de)
SG (1) SG102892G (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9302295D0 (sv) * 1993-07-02 1993-07-02 Kabi Pharmacia Ab New pharmaceutical composition
US5616330A (en) * 1994-07-19 1997-04-01 Hemagen/Pfc Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
AU8779898A (en) * 1997-08-11 1999-03-01 Weider Nutrition International, Inc. Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors
WO2000010531A1 (en) 1998-08-19 2000-03-02 Rtp Pharma Inc. Injectable aqueous dispersions of propofol
US20020155161A1 (en) * 2000-12-29 2002-10-24 Deckelbaum Richard J. Use of IV emulsions with different triglyceride composition, particle size and apolipoprotein E for targeted tissue delivery of hydrophobic compounds
MXPA04012756A (es) * 2002-07-02 2005-03-23 Altana Pharma Ag Suspension acuosa esteril que contiene ciclesonida.
PE20050941A1 (es) * 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
EA200700440A1 (ru) * 2004-09-13 2008-02-28 Бхарат Сирумс Энд Вэксинс Лтд. Композиции стабильных эмульсий для внутривенного введения, имеющие защитную эффективность
EP2663326B2 (de) * 2011-01-14 2021-09-29 Vivacelle Bio, Inc. Verfahren und zusammensetzungen zur behandlung von leiden in zusammenhang mit mangelnder blutversorgung, schocks und verletzungen
US10478505B2 (en) 2011-09-23 2019-11-19 The Regents Of The University Of California Edible oils to enhance delivery of orally administered steroids
CA2862076C (en) 2012-01-23 2020-04-21 Sage Therapeutics, Inc. Neuroactive steroid formulations and methods of treating cns disorders
US20140050789A1 (en) 2012-08-13 2014-02-20 The Regents Of The University Of California Mitigation of epileptic seizures by combination therapy using benzodiazepines and neurosteroids
IL275725B (en) 2012-08-21 2022-08-01 Sage Therapeutics Inc Methods of treating epilepsy or status epilepticus
DK2925327T3 (da) 2012-11-30 2024-03-25 Univ California Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression
JOP20200195A1 (ar) 2014-09-08 2017-06-16 Sage Therapeutics Inc سترويدات وتركيبات نشطة عصبياً، واستخداماتها
TWI798173B (zh) 2016-03-08 2023-04-11 美商賽吉醫療公司 神經活性類固醇，其組合物及用途
WO2020123551A1 (en) * 2018-12-10 2020-06-18 Halo Science LLC Stable formulations of anesthetics and associated dosage forms
EP4017498A4 (de) * 2019-08-19 2022-11-09 Arizona Board of Regents on behalf of the University of Arizona Topische neurosteroidformulierungen
US11969434B1 (en) 2022-08-29 2024-04-30 Lipocine Inc. Oral allopregnanolone compositions and methods of use
CN114344309B (zh) * 2021-12-30 2024-02-06 南京迈诺威医药科技有限公司 一种别孕烷醇酮衍生物自乳化制剂及其制备方法
US12186327B2 (en) 2022-08-29 2025-01-07 Lipocine Inc. Oral allopregnanolone compositions and methods of use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1215702B (de) * 1962-07-03 1966-05-05 Merck Ag E Verfahren zur Herstellung von 1alpha-Alkylthio-3-keto-androstanen
CA895860A (en) * 1969-11-05 1972-03-21 Kruger Gunther PROCESS FOR THE PREPARATION OF 3.alpha.-HYDROXY-5.beta.-PREGNAN-20-ONE
US3917830A (en) * 1970-12-17 1975-11-04 Glaxo Lab Ltd Steroidal anaesthetic composition for intraveneous injection
US3900561A (en) * 1970-12-17 1975-08-19 Glaxo Lab Ltd Pharmaceutical compositions
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
JPS609726B2 (ja) * 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) * 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液

Also Published As

Publication number Publication date
ES2037742T3 (es) 1993-07-01
DE3770830D1 (de) 1991-07-25
NO870560L (no) 1987-08-14
FI88676B (fi) 1993-03-15
FI870589L (fi) 1987-08-14
FI88676C (fi) 1993-06-28
EP0233849A1 (de) 1987-08-26
GR3002299T3 (en) 1992-12-30
JPS62192322A (ja) 1987-08-22
JPH0788305B2 (ja) 1995-09-27
DK62187D0 (da) 1987-02-06
SG102892G (en) 1992-12-04
FI870589A0 (fi) 1987-02-12
SE8600632D0 (sv) 1986-02-13
NO175040C (de) 1994-08-24
EP0233849B1 (de) 1991-06-19
NO870560D0 (no) 1987-02-12
DK62187A (da) 1987-08-14
DK175504B1 (da) 2004-11-15
ATE64526T1 (de) 1991-07-15
HK83293A (en) 1993-08-20
CA1301651C (en) 1992-05-26
US5028600A (en) 1991-07-02

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Legal Events

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