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RU95116650A - Гидрат кальпотриола и фармацевтическая композиция - Google Patents

Гидрат кальпотриола и фармацевтическая композиция

Info

Publication number
RU95116650A
RU95116650A RU95116650/04A RU95116650A RU95116650A RU 95116650 A RU95116650 A RU 95116650A RU 95116650/04 A RU95116650/04 A RU 95116650/04A RU 95116650 A RU95116650 A RU 95116650A RU 95116650 A RU95116650 A RU 95116650A
Authority
RU
Russia
Prior art keywords
calcipotriol
hydrate
pharmaceutical composition
crystalline form
high quality
Prior art date
Application number
RU95116650/04A
Other languages
English (en)
Other versions
RU2128646C1 (ru
Inventor
Торнгор Хансен Эрик
Dk]
Смит Раструп Андерсен Нильс
Хоффмейер Рингборг Лене
Original Assignee
Лео Фармасьютикал Продактс Лтд. А/С (Левенс Кемиске Фабрик Продукционсактиесельскаб) (Dk)
Лео Фармасьютикал Продактс Лтд. А/С (Левенс Кемиске Фабрик Продукционсактиесельскаб)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10728784&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU95116650(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Лео Фармасьютикал Продактс Лтд. А/С (Левенс Кемиске Фабрик Продукционсактиесельскаб) (Dk), Лео Фармасьютикал Продактс Лтд. А/С (Левенс Кемиске Фабрик Продукционсактиесельскаб) filed Critical Лео Фармасьютикал Продактс Лтд. А/С (Левенс Кемиске Фабрик Продукционсактиесельскаб) (Dk)
Publication of RU95116650A publication Critical patent/RU95116650A/ru
Application granted granted Critical
Publication of RU2128646C1 publication Critical patent/RU2128646C1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/02—Apparatus characterised by being constructed of material selected for its chemically-resistant properties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/321—Catalytic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/327—Formation of non-aromatic carbon-to-carbon double bonds only
    • C07C5/333—Catalytic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C5/00—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms
    • C07C5/32—Preparation of hydrocarbons from hydrocarbons containing the same number of carbon atoms by dehydrogenation with formation of free hydrogen
    • C07C5/327—Formation of non-aromatic carbon-to-carbon double bonds only
    • C07C5/333—Catalytic processes
    • C07C5/3335—Catalytic processes with metals
    • C07C5/3337—Catalytic processes with metals of the platinum group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02—Apparatus characterised by their chemically-resistant properties
    • B01J2219/0204—Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02—Apparatus characterised by their chemically-resistant properties
    • B01J2219/0204—Apparatus characterised by their chemically-resistant properties comprising coatings on the surfaces in direct contact with the reactive components
    • B01J2219/0236—Metal based
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/02—Apparatus characterised by their chemically-resistant properties
    • B01J2219/025—Apparatus characterised by their chemically-resistant properties characterised by the construction materials of the reactor vessel proper
    • B01J2219/0277—Metal based
    • B01J2219/0286—Steel
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals
    • C07C2523/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals of the platinum group metals
    • C07C2523/42—Platinum

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Данное изобретение касается кадьципотриола-гидрата новой кристаллической формы кальципотриола, с техническими свойствами высокого качества и превосходной стабильностью.

Claims (1)

  1. Данное изобретение касается кадьципотриола-гидрата новой кристаллической формы кальципотриола, с техническими свойствами высокого качества и превосходной стабильностью.
RU95116650A 1993-01-15 1994-01-07 Гидрат кальципотриола, фармацевтическая композиция RU2128646C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939300763A GB9300763D0 (en) 1993-01-15 1993-01-15 Chemical compound
GB9300763.1 1993-01-15
PCT/DK1994/000011 WO1994015912A1 (en) 1993-01-15 1994-01-07 New crystalline form of a vitamin d analogue

Publications (2)

Publication Number Publication Date
RU95116650A true RU95116650A (ru) 1997-06-10
RU2128646C1 RU2128646C1 (ru) 1999-04-10

Family

ID=10728784

Family Applications (1)

Application Number Title Priority Date Filing Date
RU95116650A RU2128646C1 (ru) 1993-01-15 1994-01-07 Гидрат кальципотриола, фармацевтическая композиция

Country Status (17)

Country Link
US (2) US5763426A (ru)
EP (1) EP0679154B1 (ru)
JP (1) JP3729847B2 (ru)
KR (1) KR100309751B1 (ru)
CN (1) CN1040746C (ru)
AT (1) ATE159717T1 (ru)
AU (1) AU663249B2 (ru)
CA (1) CA2151730C (ru)
DE (1) DE69406529T2 (ru)
DK (1) DK0679154T3 (ru)
ES (1) ES2111287T3 (ru)
FI (1) FI108638B (ru)
GB (1) GB9300763D0 (ru)
GR (1) GR3025668T3 (ru)
NZ (1) NZ259679A (ru)
RU (1) RU2128646C1 (ru)
WO (1) WO1994015912A1 (ru)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU710931B2 (en) * 1996-02-28 1999-09-30 Sumitomo Pharmaceuticals Company, Limited Crystalline vitamin D derivative
US8263580B2 (en) 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
ME00298B (me) * 1999-04-23 2011-05-10 Leo Pharmaceutical Products Ltd As Løvens Kemiske Fabrik Produktionsaktieselskab Farmaceutski preparat
US20090098065A1 (en) * 2000-01-11 2009-04-16 Avikam Harel Composition and methods for the treatment of skin disorders
WO2004046097A1 (en) * 2002-11-18 2004-06-03 Teva Pharmaceutical Industries Ltd. A crystallization method for purification of calcipotriene
MY139521A (en) * 2004-03-18 2009-10-30 Leo Pharma As Stereoselective synthesis of vitamin d analogues
FR2871696B1 (fr) * 2004-06-17 2006-11-10 Galderma Sa Composition topique pour le traitement du psoriasis
TWI318203B (en) * 2004-09-01 2009-12-11 Leo Pharma As Epimerization of allylic alcohols
AU2006253913B2 (en) * 2005-06-01 2010-09-16 Mayne Pharma Llc Vitamin formulation
US7989631B2 (en) * 2006-02-10 2011-08-02 Amgen Inc. Hydrate forms of AMG706
EP1844010B1 (en) 2006-03-17 2013-02-13 Leo Pharma A/S Isomerisation of pharmaceutical intermediates
KR20110113664A (ko) * 2006-08-29 2011-10-17 테바 파마슈티컬 인더스트리즈 리미티드 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물
US20100056644A1 (en) * 2006-11-29 2010-03-04 Nilendu Sen Pharmaceutical compositions containing anhydrous calcipotriene
ES2272198B1 (es) * 2006-12-28 2008-06-01 Laboratorios Viñas S.A. Procedimiento para la obtencion de hidrato de calcipotriol.
EP1970048A1 (en) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Polyaphron topical composition with vitamin D
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
EP2008651A1 (en) 2007-06-26 2008-12-31 Drug Delivery Solutions Limited A bioerodible patch
EP2300408B1 (en) * 2008-05-08 2016-04-13 United Therapeutics Corporation Process for the preparation of treprostinil monohydrate and its use for storage and shipping
WO2011002756A2 (en) * 2009-07-01 2011-01-06 Vitamin Derivatives, Inc. Vitamin d compounds and methods for preparing same
CN102770121B (zh) 2009-12-22 2014-10-15 利奥制药有限公司 包含溶剂混合物和维生素d衍生物或类似物的药物组合物
US9254296B2 (en) 2009-12-22 2016-02-09 Leo Pharma A/S Pharmaceutical composition comprising vitamin D analogue and cosolvent-surfactant mixture
NZ600999A (en) 2009-12-22 2014-06-27 Leo Pharma As Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants
MX2012007234A (es) * 2009-12-22 2012-07-30 Leo Pharma As Nanocristales de monohidrato de calciprotiol.
BR112012015447A2 (pt) * 2009-12-22 2016-03-15 Leo Pharma As composição tópica para aplicação cutânea
NZ603470A (en) 2010-06-11 2014-12-24 Leo Pharma As A pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid
SI2686017T1 (sl) 2011-03-14 2019-11-29 Drug Delivery Solutions Ltd Očesna sestava
RU2602171C2 (ru) 2011-03-24 2016-11-10 Лео Фарма А/С Композиция, содержащая липидные наночастицы и кортикостероид или производное витамина d
JP5652723B2 (ja) * 2012-08-17 2015-01-14 フォーモサ・ラボラトリーズ・インコーポレーテッド マキサカルシトールの新しい結晶形態
CN103724162A (zh) * 2014-01-07 2014-04-16 成都医路康医学技术服务有限公司 一种银屑病治疗药物卡泊三醇溶剂化物的制备方法
MA41818A (fr) 2015-03-27 2018-01-30 Leo Pharma As Timbre à micro-aiguilles pour administration d'un principe actif à la peau
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2457282A1 (fr) * 1979-05-23 1980-12-19 Roussel Uclaf Nouveau derive du 1a,25 dihydroxy cholecalciferol, son procede de preparation et son application comme medicament
JPS59104358A (ja) 1982-12-03 1984-06-16 Teijin Ltd １α，２４−ジヒドロキシコレカルシフエロ−ルの一水塩及びその製造法
JPH07100685B2 (ja) * 1985-08-02 1995-11-01 レオ・ファ−マシュ−ティカル・プロダクツ・リミテッド・エイ／エス（レ−ベンス・ケミスケ・ファブリック・プロデュクチオンスアクチ−セルスカブ） 新規ビタミンｄ類似体
GB9004544D0 (en) * 1990-03-01 1990-04-25 Leo Pharm Prod Ltd Novel treatment ii

Also Published As

Publication number Publication date
AU5857394A (en) 1994-08-15
FI952797A0 (fi) 1995-06-07
DE69406529T2 (de) 1998-05-28
JPH08505612A (ja) 1996-06-18
ES2111287T3 (es) 1998-03-01
FI108638B (fi) 2002-02-28
FI952797L (fi) 1995-06-07
KR100309751B1 (ko) 2002-11-08
AU663249B2 (en) 1995-09-28
DE69406529D1 (de) 1997-12-04
CN1040746C (zh) 1998-11-18
DK0679154T3 (da) 1998-03-30
ATE159717T1 (de) 1997-11-15
KR950704249A (ko) 1995-11-17
GB9300763D0 (en) 1993-03-03
JP3729847B2 (ja) 2005-12-21
CA2151730A1 (en) 1994-07-21
WO1994015912A1 (en) 1994-07-21
RU2128646C1 (ru) 1999-04-10
US5763426A (en) 1998-06-09
CA2151730C (en) 2005-01-04
GR3025668T3 (en) 1998-03-31
CN1115979A (zh) 1996-01-31
EP0679154B1 (en) 1997-10-29
USRE39706E1 (en) 2007-06-26
EP0679154A1 (en) 1995-11-02
NZ259679A (en) 1996-11-26

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