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RU94040895A - Устройство для разделения пробы жидкости, способ разделения пробы жидкости, способ разделения жидкости на два или большее число компонентов, кольцевой узел, способ отделения компонента крови от пробы жидкости, способ получения фибрин-мономера из крови - Google Patents

Устройство для разделения пробы жидкости, способ разделения пробы жидкости, способ разделения жидкости на два или большее число компонентов, кольцевой узел, способ отделения компонента крови от пробы жидкости, способ получения фибрин-мономера из крови

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Publication number
RU94040895A
RU94040895A RU94040895/14A RU94040895A RU94040895A RU 94040895 A RU94040895 A RU 94040895A RU 94040895/14 A RU94040895/14 A RU 94040895/14A RU 94040895 A RU94040895 A RU 94040895A RU 94040895 A RU94040895 A RU 94040895A
Authority
RU
Russia
Prior art keywords
separation
liquid sample
phase
vessel
piston
Prior art date
Application number
RU94040895/14A
Other languages
English (en)
Other versions
RU2133468C1 (ru
Inventor
Холм Нильс-Эрик
Dk]
Original Assignee
Бристоль-Мейерз Сквибб Компани (US)
Бристоль-Мейерз Сквибб Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Бристоль-Мейерз Сквибб Компани (US), Бристоль-Мейерз Сквибб Компани filed Critical Бристоль-Мейерз Сквибб Компани (US)
Publication of RU94040895A publication Critical patent/RU94040895A/ru
Application granted granted Critical
Publication of RU2133468C1 publication Critical patent/RU2133468C1/ru

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B04B1/04—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with inserted separating walls
    • B04B1/06—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with inserted separating walls of cylindrical shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B1/00—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles
    • B04B1/02—Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles without inserted separating walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B7/00—Elements of centrifuges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/0485—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with a displaceable piston in the centrifuge chamber
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Ecology (AREA)
  • Centrifugal Separators (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • External Artificial Organs (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

При способе разделения пробы жидкости, имеющей фазовые части с различными плотностями, путем центробежного разделения применяют сосуд для разделения фаз. Сосуд для разделения фаз содержит корпус, имеющий концентричные внутреннюю и наружную стенки, определяющие продольную ось, и верхнюю стенку, а также поршень, представляющий собой нижнюю стенку корпуса. Поршень вместе с наружной цилиндрической стенкой, внутренней цилиндрической стенкой и верхней стенкой ограничивает кольцевую камеру для приема пробы жидкости. Поршень может перемещаться в кольцевой камере для слива фазовой части, отделенной от пробы жидкости, через сливной канал, сообщающийся с кольцевой камерой. Сосуд для разделения фаз имеет также реакционную камеру, в которой обрабатывают фазовую часть, удаленную из кольцевой камеры. Устройство также содержит средства для подачи пробы жидкости в кольцевую камеру, электродвигатель для вращения сосуда для разделения фаз вокруг его продольной оси с частотой вращения, вызывающей разделение пробы жидкости на фазовые части, и исполнительный механизм для перемещения поршня в кольцевой камере.

Claims (1)

  1. При способе разделения пробы жидкости, имеющей фазовые части с различными плотностями, путем центробежного разделения применяют сосуд для разделения фаз. Сосуд для разделения фаз содержит корпус, имеющий концентричные внутреннюю и наружную стенки, определяющие продольную ось, и верхнюю стенку, а также поршень, представляющий собой нижнюю стенку корпуса. Поршень вместе с наружной цилиндрической стенкой, внутренней цилиндрической стенкой и верхней стенкой ограничивает кольцевую камеру для приема пробы жидкости. Поршень может перемещаться в кольцевой камере для слива фазовой части, отделенной от пробы жидкости, через сливной канал, сообщающийся с кольцевой камерой. Сосуд для разделения фаз имеет также реакционную камеру, в которой обрабатывают фазовую часть, удаленную из кольцевой камеры. Устройство также содержит средства для подачи пробы жидкости в кольцевую камеру, электродвигатель для вращения сосуда для разделения фаз вокруг его продольной оси с частотой вращения, вызывающей разделение пробы жидкости на фазовые части, и исполнительный механизм для перемещения поршня в кольцевой камере.
RU94040895A 1993-11-19 1994-11-18 Устройство для разделения пробы жидкости, способ разделения пробы жидкости, способ разделения жидкости на два или большее число компонентов, кольцевой узел, способ отделения компонента крови от пробы жидкости, способ получения фибрин-мономера из крови RU2133468C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15598493A 1993-11-19 1993-11-19
US155,984 1993-11-19
US155984 1993-11-19

Publications (2)

Publication Number Publication Date
RU94040895A true RU94040895A (ru) 1996-09-20
RU2133468C1 RU2133468C1 (ru) 1999-07-20

Family

ID=22557593

Family Applications (1)

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RU94040895A RU2133468C1 (ru) 1993-11-19 1994-11-18 Устройство для разделения пробы жидкости, способ разделения пробы жидкости, способ разделения жидкости на два или большее число компонентов, кольцевой узел, способ отделения компонента крови от пробы жидкости, способ получения фибрин-мономера из крови

Country Status (26)

Country Link
US (6) US5603845A (ru)
EP (2) EP1152241A3 (ru)
JP (1) JP3745397B2 (ru)
KR (1) KR950013582A (ru)
CN (1) CN1044977C (ru)
AT (1) ATE213329T1 (ru)
AU (1) AU688390B2 (ru)
BR (1) BR9404484A (ru)
CA (1) CA2136148C (ru)
CZ (1) CZ280694A3 (ru)
DE (1) DE69429852T2 (ru)
DK (1) DK0654669T3 (ru)
ES (1) ES2170763T3 (ru)
FI (2) FI114340B (ru)
HU (1) HU215246B (ru)
IL (1) IL111524A (ru)
MX (1) MXPA99004700A (ru)
NO (1) NO314715B1 (ru)
NZ (1) NZ264859A (ru)
PL (1) PL176963B1 (ru)
PT (1) PT654669E (ru)
RU (1) RU2133468C1 (ru)
SG (1) SG49212A1 (ru)
SK (1) SK138394A3 (ru)
UA (1) UA27898C2 (ru)
ZA (1) ZA948564B (ru)

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