RU2018132595A3 - - Google Patents
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- RU2018132595A3 RU2018132595A3 RU2018132595A RU2018132595A RU2018132595A3 RU 2018132595 A3 RU2018132595 A3 RU 2018132595A3 RU 2018132595 A RU2018132595 A RU 2018132595A RU 2018132595 A RU2018132595 A RU 2018132595A RU 2018132595 A3 RU2018132595 A3 RU 2018132595A3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662318014P | 2016-04-04 | 2016-04-04 | |
US62/318,014 | 2016-04-04 | ||
US201662378543P | 2016-08-23 | 2016-08-23 | |
US62/378,543 | 2016-08-23 | ||
PCT/US2017/025718 WO2017176628A1 (en) | 2016-04-04 | 2017-04-03 | Methods for solid tumor treatment |
Publications (3)
Publication Number | Publication Date |
---|---|
RU2018132595A RU2018132595A (ru) | 2020-05-12 |
RU2018132595A3 true RU2018132595A3 (ru) | 2020-06-22 |
RU2737934C2 RU2737934C2 (ru) | 2020-12-07 |
Family
ID=58668944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2018132595A RU2737934C2 (ru) | 2016-04-04 | 2017-04-03 | Способы лечения солидных опухолей |
Country Status (14)
Country | Link |
---|---|
US (6) | US10391090B2 (ru) |
EP (2) | EP3854381A1 (ru) |
JP (2) | JP6970683B2 (ru) |
KR (3) | KR20230017354A (ru) |
CN (2) | CN114767860A (ru) |
AU (2) | AU2017246316B2 (ru) |
BR (1) | BR112018069628A2 (ru) |
CA (1) | CA3018989A1 (ru) |
DK (1) | DK3439635T3 (ru) |
ES (1) | ES2858092T3 (ru) |
PT (1) | PT3439635T (ru) |
RU (1) | RU2737934C2 (ru) |
SG (2) | SG10201913409VA (ru) |
WO (1) | WO2017176628A1 (ru) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9814685B2 (en) | 2015-06-04 | 2017-11-14 | Crititech, Inc. | Taxane particles and their use |
KR102742522B1 (ko) | 2015-09-16 | 2024-12-12 | 디에프비 소리아, 엘엘씨 | 약물 나노입자 전달체 및 이의 제조방법 |
DK3439635T3 (da) | 2016-04-04 | 2021-03-08 | Crititech Inc | Formuleringer til behandling af fast tumor |
ES2955884T3 (es) | 2017-03-15 | 2023-12-07 | Dfb Soria Llc | Terapia tópica para el tratamiento de malignidades de la piel con nanoparticulas de taxanos |
ES2980123T3 (es) * | 2017-06-09 | 2024-09-30 | Crititech Inc | Composiciones para uso en el tratamiento de quistes epiteliales mediante inyección intraquística de partículas antineoplásicas |
CA3063436A1 (en) | 2017-06-14 | 2018-12-20 | Crititech, Inc. | Methods for treating lung disorders |
KR20250057947A (ko) | 2017-10-03 | 2025-04-29 | 크리티테크, 인크. | 암의 치료를 위한 면역치료제의 전신 전달과 조합된 항신생물성 입자의 국소 전달 |
KR20200106911A (ko) | 2018-01-05 | 2020-09-15 | 크리티테크, 인크. | 탁산 입자의 국소 투여에 의한 방광암의 치료 |
KR20200132963A (ko) | 2018-03-16 | 2020-11-25 | 디에프비 소리아, 엘엘씨 | 탁산의 나노입자를 사용하는 자궁경부 상피내 신생물 (cin) 및 자궁경부 암의 치료를 위한 국소적 요법 |
WO2019231499A1 (en) * | 2018-05-31 | 2019-12-05 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for treatment of cancer |
WO2019231498A1 (en) | 2018-05-31 | 2019-12-05 | Crititech, Inc. | Treatment of kidney tumors by intratumoral injection of taxane particles |
KR20210016511A (ko) * | 2018-05-31 | 2021-02-16 | 크리티테크, 인크. | 입양 세포 요법 및 암 백신을 위한 종양 특이적 면역 세포를 대상체로부터 단리하는 방법 |
WO2020072090A1 (en) * | 2018-10-03 | 2020-04-09 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for production of tertiary lymphoid structures (tls) |
KR20210078505A (ko) | 2018-10-16 | 2021-06-28 | 유에스 나노 푸드 앤 드럭 인코포레이티드 | 종양내 주사 제형 |
US12140589B2 (en) * | 2019-04-24 | 2024-11-12 | Kyocera Corporation | Gas detection system |
CA3169441A1 (en) | 2020-04-13 | 2021-10-21 | US Nano Food & Drug INC | Basic chemotherapeutic intratumour injection formulation |
CN117222417A (zh) * | 2021-04-26 | 2023-12-12 | 克里蒂泰克公司 | 顺铂颗粒及其用途 |
KR102712163B1 (ko) | 2022-09-29 | 2024-09-30 | 주식회사 동희산업 | 차량용 고압용기의 고정기구 |
KR102712164B1 (ko) | 2022-09-29 | 2024-09-30 | 주식회사 동희산업 | 수소탱크 고정장치 |
US20240156861A1 (en) * | 2022-10-25 | 2024-05-16 | Crititech, Inc. | Cisplatin particles and uses thereof |
Family Cites Families (123)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
US6749868B1 (en) | 1993-02-22 | 2004-06-15 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
US5994341A (en) | 1993-07-19 | 1999-11-30 | Angiogenesis Technologies, Inc. | Anti-angiogenic Compositions and methods for the treatment of arthritis |
GB9413202D0 (en) | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
US5626862A (en) | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US5874481A (en) | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
US5874029A (en) | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
US5833891A (en) | 1996-10-09 | 1998-11-10 | The University Of Kansas | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents |
US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
AU741439B2 (en) | 1996-12-30 | 2001-11-29 | Battelle Memorial Institute | Formulation and method for treating neoplasms by inhalation |
KR100789008B1 (ko) | 1997-06-27 | 2007-12-26 | 아브락시스 바이오사이언스 인크. | 신규 약물 제제 |
US6117949A (en) | 1998-10-01 | 2000-09-12 | Macromed, Inc. | Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
JP3418751B2 (ja) * | 1998-01-22 | 2003-06-23 | 参天製薬株式会社 | フルオロメトロン懸濁型点眼剤 |
IL131217A0 (en) | 1998-03-10 | 2001-01-28 | Napro Biotherapeutics Inc | Novel methods and compositions for delivery of taxanes |
US6221153B1 (en) | 1998-06-09 | 2001-04-24 | Trevor Percival Castor | Method for producing large crystals of complex molecules |
US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
US6113795A (en) | 1998-11-17 | 2000-09-05 | The University Of Kansas | Process and apparatus for size selective separation of micro- and nano-particles |
EP1275382A3 (de) | 1998-11-25 | 2003-02-12 | Universitätsklinikum Freiburg | Hyperforin als Zytostatikum sowie Hyperforin-Salbe oder -Creme als Applikationsform |
US6537585B1 (en) | 1999-03-26 | 2003-03-25 | Guilford Pharmaceuticals, Inc. | Methods and compositions for treating solid tumors |
US7217735B1 (en) | 1999-04-09 | 2007-05-15 | Au Jessie L-S | Methods and compositions for enhancing delivery of therapeutic agents to tissues |
BR0010984A (pt) | 1999-05-27 | 2002-04-30 | Acusphere Inc | Matrizes porosas de medicamento e processos para fabricação das mesmas |
CN100376291C (zh) * | 1999-05-27 | 2008-03-26 | 阿库斯菲尔公司 | 多孔药物基质及其制造方法 |
US6610317B2 (en) * | 1999-05-27 | 2003-08-26 | Acusphere, Inc. | Porous paclitaxel matrices and methods of manufacture thereof |
US6858199B1 (en) | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
US6616849B1 (en) | 1999-08-25 | 2003-09-09 | Shimadzu Corporation | Method of and system for continuously processing liquid materials, and the product processed thereby |
EP1235598A2 (en) | 1999-11-12 | 2002-09-04 | Angiotech Pharmaceuticals, Inc. | Compositions of a combination of radioactive therapy and cell-cycle inhibitors |
US6620351B2 (en) | 2000-05-24 | 2003-09-16 | Auburn University | Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer |
US6562952B1 (en) | 2000-10-31 | 2003-05-13 | The University Of Kansas | Precipitation of proteins from organic solutions |
US20020081339A1 (en) | 2000-12-22 | 2002-06-27 | Philippe Menei | Treatment of inoperable tumors by stereotactic injection of microspheres |
EP1387676A2 (en) | 2001-05-01 | 2004-02-11 | Angiotech Pharmaceuticals, Inc. | Compositions comprising an anti-microtubule agent and a polypeptide or a polysaccharide and the use thereof for the preparation of a medicament for the treatment of inflammatory conditions |
DK1401563T4 (en) | 2001-07-02 | 2016-01-11 | Cerbios Pharma Sa | A process for producing micro and / or nano-particles |
US20030054042A1 (en) | 2001-09-14 | 2003-03-20 | Elaine Liversidge | Stabilization of chemical compounds using nanoparticulate formulations |
US20030134810A1 (en) | 2001-10-09 | 2003-07-17 | Chris Springate | Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents |
US20030087837A1 (en) | 2001-10-15 | 2003-05-08 | Jonas Jeffrey M. | Compositions and methods for delivery of poorly water soluble drugs and methods of treatment |
US20030166509A1 (en) | 2001-11-20 | 2003-09-04 | Advanced Inhalation Research, Inc. | Compositions for sustained action product delivery and methods of use thereof |
WO2003075977A2 (en) | 2002-03-05 | 2003-09-18 | Cleveland State University | Agglomerated particles for aerosol drug delivery |
WO2003080027A1 (en) | 2002-03-20 | 2003-10-02 | Elan Pharma International, Ltd. | Nanoparticulate compositions of angiogenesis inhibitors |
CA2483218C (en) | 2002-04-25 | 2012-07-10 | Nektar Therapeutics Uk Ltd | Particulate materials |
EA200401250A1 (ru) * | 2002-04-26 | 2005-06-30 | Тева Фармасьютикал Индастриес Лтд. | Фармацевтические композиции на основе микрочастиц для внутриопухолевого введения |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
CN1255394C (zh) * | 2002-06-24 | 2006-05-10 | 成都思摩纳米技术有限公司 | 紫杉醇纳米微粒的制备方法及应用 |
KR100573289B1 (ko) | 2002-07-20 | 2006-04-24 | 대화제약 주식회사 | 방광내 투여를 통한 방광암치료용 파클리탁셀 조성물 및그의 제조 방법 |
AU2003304108B2 (en) | 2002-10-30 | 2007-03-22 | Spherics, Inc. | Nanoparticulate bioactive agents |
KR100508518B1 (ko) | 2002-11-13 | 2005-08-17 | 한미약품 주식회사 | 초임계유체 공정을 이용한 파클리탁셀 고체분산체의 제조방법 및 이 방법으로 제조된 파클리탁셀 고체분산체 |
ES2685436T3 (es) | 2002-12-09 | 2018-10-09 | Abraxis Bioscience, Llc | Composiciones y procedimientos para administración de agentes farmacológicos |
US7455797B2 (en) | 2003-02-28 | 2008-11-25 | Ferro Corporation | Method and apparatus for producing particles using supercritical fluid |
AU2004228008B2 (en) | 2003-04-03 | 2008-11-06 | Jessie L.-S. Au | Tumor-targeting drug-loaded particles |
US20060147535A1 (en) * | 2003-04-16 | 2006-07-06 | Poongunran Muthukumaran | Methods for and compositions of anticancer medicaments |
US20050059613A1 (en) | 2003-07-08 | 2005-03-17 | Bahram Memarzadeh | Compositions and methods for the enhanced uptake of therapeutic agents through the bladder epithelium |
US8021831B2 (en) | 2003-08-25 | 2011-09-20 | Board Of Regents, The University Of Texas System | Taxane chemosensitivity prediction test |
JP2007001865A (ja) | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤 |
US20080063699A1 (en) | 2003-10-15 | 2008-03-13 | Michael Teifel | Method of Administering Cationic Liposomes Comprising an Active Drug |
US7208106B2 (en) | 2003-10-24 | 2007-04-24 | Ferro Corporation | Method of forming particles |
ATE509618T1 (de) | 2003-11-05 | 2011-06-15 | Elan Pharma Int Ltd | Nanoteilchenförmige zusammensetzungen mit einem peptid als oberflächenstabilisator |
GB0402963D0 (en) | 2004-02-11 | 2004-03-17 | Univ Nottingham | Counter current mixing device for two different fluids |
US8043631B2 (en) | 2004-04-02 | 2011-10-25 | Au Jessie L S | Tumor targeting drug-loaded particles |
JP5164381B2 (ja) | 2004-10-29 | 2013-03-21 | 株式会社奈良機械製作所 | 微細粒子の造粒方法 |
US20060159712A1 (en) | 2004-12-14 | 2006-07-20 | Transave, Inc. | Lipid particles comprising bioactive agents, methods of preparing and uses thereof |
ES2265262B1 (es) | 2005-01-31 | 2008-03-01 | Activery Biotech, S.L.(Titular Al 50%) | Procedimiento para la obtencion de sistemas micro- y nanodispersos. |
US8735394B2 (en) | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
WO2006091780A2 (en) * | 2005-02-24 | 2006-08-31 | Elan Pharma International Limited | Nanoparticulate formulations of docetaxel and analogues thereof |
US7872050B2 (en) | 2005-03-14 | 2011-01-18 | Yaupon Therapeutics Inc. | Stabilized compositions of volatile alkylating agents and methods of using thereof |
JP5635231B2 (ja) | 2005-03-31 | 2014-12-03 | リッズ エービーLidds Ab | 活性物質の局所送達に基づく前立腺疾患の治療方法 |
CN1923189A (zh) | 2005-08-30 | 2007-03-07 | 孔庆忠 | 一种紫杉碱类抗癌药物的缓释注射剂 |
JP5368093B2 (ja) | 2005-08-31 | 2013-12-18 | アブラクシス バイオサイエンス, エルエルシー | 増大した安定性を有する難水溶性薬剤の組成物および調製の方法 |
AU2006322458A1 (en) | 2005-12-11 | 2007-06-14 | Scf Technologies A/S | Production of nanosized materials |
US8906392B2 (en) | 2005-12-16 | 2014-12-09 | University Of Kansas | Nanocluster compositions and methods |
AR054215A1 (es) | 2006-01-20 | 2007-06-13 | Eriochem Sa | Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit |
CN101336899A (zh) | 2006-01-25 | 2009-01-07 | 济南帅华医药科技有限公司 | 含紫杉烷的抗癌缓释注射剂 |
DE602007005231D1 (de) | 2006-03-14 | 2010-04-22 | Lidds Ab | Bioresorbierbare zusammensetzung mit kontrollierter freisetzung |
EP2077823B1 (en) | 2006-10-11 | 2012-06-27 | Crititech, Inc. | Method for precipitation of small medicament particles into use containers |
TWI405590B (zh) | 2007-04-06 | 2013-08-21 | Activus Pharma Co Ltd | 微粉碎化有機化合物粒子之製法 |
EP2146707A2 (en) | 2007-05-03 | 2010-01-27 | Abraxis BioScience, LLC | Methods and compositions for treating pulmonary hypertension |
WO2009006590A2 (en) | 2007-07-04 | 2009-01-08 | Dr. Reddy's Laboratories Ltd. | Docetaxel process and polymorphs |
CN101129338A (zh) | 2007-08-27 | 2008-02-27 | 四川大学 | 超临界流体新技术微细化抗癌药物紫杉醇 |
CN104096236A (zh) | 2008-03-06 | 2014-10-15 | 日东电工株式会社 | 用于治疗癌症的聚合物紫杉醇结合物和方法 |
PT2345426E (pt) | 2008-09-19 | 2014-06-09 | Activus Pharma Co Ltd | Composto orgânico compósito em pó para utilização médica, método de produção do mesmo e suspensão do mesmo |
CA2745238A1 (en) | 2008-12-02 | 2010-06-10 | Biocompatibles Uk Limited | Pancreatic tumour treatment |
PT104693B (pt) | 2009-07-27 | 2011-11-24 | Univ Lisboa | Nanopartículas lipídicas semi-sólidas contendo um agente antineoplásico e seu processo de preparação |
SG178885A1 (en) | 2009-08-24 | 2012-04-27 | Baylor College Medicine | Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses |
CN101829061A (zh) * | 2010-05-14 | 2010-09-15 | 无锡纳生生物科技有限公司 | 一种紫杉醇纳米颗粒组合物及其制备方法 |
PH12012502378A1 (en) | 2010-06-02 | 2013-02-11 | Abraxis Bioscience Llc | Methods of treating bladder cancer |
CN103209710B (zh) | 2010-09-21 | 2016-04-06 | 克里斯特欧德里发里有限公司 | 用于药物递送系统中组分的短暂连接的可调的、可生物降解的接头分子以及利用其制备的药物递送系统 |
EP2627317A4 (en) | 2010-10-15 | 2014-08-20 | Glaxo Group Ltd | MEDICINAL FORMULATIONS FROM AGGREGATED NANOPARTICLES AND THEIR PREPARATION AND USE |
WO2012096995A2 (en) | 2011-01-11 | 2012-07-19 | Boston Scientific Scimed, Inc. | Coated medical devices |
PT2699233T (pt) | 2011-04-20 | 2017-07-03 | Univ Sydney | Material particulado e toxina celular para utilização no tratamento de um tumor sólido |
US20140154269A1 (en) | 2011-04-26 | 2014-06-05 | The Methodist Hospital Research Institute | Targeted nanovectors and their use for treatment of brain tumors |
US10973763B2 (en) | 2011-06-17 | 2021-04-13 | Berg Llc | Inhalable pharmaceutical compositions |
WO2013002636A1 (en) | 2011-06-27 | 2013-01-03 | Cristal Delivery B.V. | Controlled release system |
FR2980683B1 (fr) | 2011-09-30 | 2014-11-21 | Univ Paris Curie | Dispositif de guidage d'un instrument medical insere dans une voie naturelle ou une voie artificielle d'un patient |
CN102488682A (zh) | 2011-11-22 | 2012-06-13 | 四川九章生物化工科技发展有限公司 | 绿原酸的抗癌新用途 |
US10555911B2 (en) | 2012-05-04 | 2020-02-11 | Yale University | Highly penetrative nanocarriers for treatment of CNS disease |
TW201408304A (zh) | 2012-08-31 | 2014-03-01 | Cathay General Hospital | 一種合併抗癌藥物及荷爾蒙之抗腎細胞癌藥物及其製造方法 |
DK2897620T3 (da) | 2012-09-21 | 2020-08-17 | Intensity Therapeutics Inc | Fremgangsmåde til behandling af cancer |
US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
BR112015018838B1 (pt) * | 2013-02-28 | 2020-12-15 | Pfizer Inc. | Composição oral líquida com estabilidade melhorada e seu processo para a preparação |
US9925512B2 (en) | 2013-03-14 | 2018-03-27 | Crititech, Inc. | Equipment assembly for and method of processing particles |
US8778181B1 (en) | 2013-03-14 | 2014-07-15 | Crititech, Inc. | Equipment assembly for and method of processing particles |
EP2978420A4 (en) | 2013-03-28 | 2016-12-21 | Bbs Nanotechnology Ltd | STABLE NANO COMPOSITION WITH DOXORUBICIN, PROCESS FOR THE PREPARATION THEREOF, THE USE THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREWITH |
WO2014169137A1 (en) | 2013-04-10 | 2014-10-16 | Massachusetts Institute Of Technology | Local drug delivery devices and methods for treating cancer |
JP6595463B2 (ja) | 2013-10-16 | 2019-10-23 | ユニベルシテ リブレ デ ブリュッセル | 気道に影響する増殖性疾患の処置に有用な製剤 |
IL296657A (en) | 2013-12-17 | 2022-11-01 | Genentech Inc | Methods of treating cancers using pd-1 axis binding antagonists and taxanes |
AU2014368898B2 (en) | 2013-12-20 | 2020-06-11 | Dana-Farber Cancer Institute, Inc. | Combination therapy with neoantigen vaccine |
WO2015103005A1 (en) | 2014-01-03 | 2015-07-09 | Research Institute At Nationwide Children's Hospital | Amphiphilic amine compounds and their use as therapeutic agents and nanocarriers |
TWI601542B (zh) | 2014-04-18 | 2017-10-11 | 林信湧 | 一種用於治療肺癌之吸入式醫藥組成物及其備製方法 |
US20150342872A1 (en) | 2014-06-01 | 2015-12-03 | Crititech, Inc. | Use of Paclitaxel Particles |
WO2015191590A2 (en) | 2014-06-09 | 2015-12-17 | Biomed Valley Discoveries, Inc. | Combination therapies targeting tumor-associated stroma or tumor cells and microtubules |
EP3234193B1 (en) | 2014-12-19 | 2020-07-15 | Massachusetts Institute of Technology | Molecular biomarkers for cancer immunotherapy |
US9814685B2 (en) | 2015-06-04 | 2017-11-14 | Crititech, Inc. | Taxane particles and their use |
KR102742522B1 (ko) | 2015-09-16 | 2024-12-12 | 디에프비 소리아, 엘엘씨 | 약물 나노입자 전달체 및 이의 제조방법 |
KR20180058759A (ko) | 2015-09-25 | 2018-06-01 | 제트와이 테라퓨틱스 인코포레이티드 | 폴리사카라이드-비타민 접합체를 포함하는 미립자를 기재로 하는 약물 제제 |
DE202016006620U1 (de) | 2015-10-28 | 2017-04-12 | Qass Gmbh | Vorrichtungen zum Beobachten eines Magnetfelds eines Materialvolumens |
EP3405567A4 (en) | 2016-01-20 | 2019-10-30 | Fate Therapeutics, Inc. | COMPOUNDS AND METHODS FOR IMMUNOCELL MODULATION IN ADOPTIVE IMMUNOTHERAPIES |
DK3439635T3 (da) | 2016-04-04 | 2021-03-08 | Crititech Inc | Formuleringer til behandling af fast tumor |
CN107281502B (zh) | 2016-04-05 | 2021-05-04 | 上海市肿瘤研究所 | 一种复合显影温敏凝胶栓塞剂、制备方法及其应用 |
EP3429633B1 (en) | 2016-04-15 | 2021-02-24 | Cellectis | A method of engineering drug-specific hypersensitive t-cells for immunotherapy by gene inactivation |
US9567399B1 (en) | 2016-06-20 | 2017-02-14 | Kymab Limited | Antibodies and immunocytokines |
KR102462041B1 (ko) | 2016-09-01 | 2022-11-02 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 암 치료용 담체-pd-l1 결합제 조성물 |
WO2018170210A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of vulvar intraepithelial neoplasia (vin) and genital warts using nanoparticles of taxanes |
WO2018170207A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of skin keratoses using nanoparticles of taxanes |
ES2955884T3 (es) | 2017-03-15 | 2023-12-07 | Dfb Soria Llc | Terapia tópica para el tratamiento de malignidades de la piel con nanoparticulas de taxanos |
ES2980123T3 (es) | 2017-06-09 | 2024-09-30 | Crititech Inc | Composiciones para uso en el tratamiento de quistes epiteliales mediante inyección intraquística de partículas antineoplásicas |
CA3063436A1 (en) | 2017-06-14 | 2018-12-20 | Crititech, Inc. | Methods for treating lung disorders |
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