PT777498E - Conjugados de complexos metalicos e oligonucleotidos - Google Patents
Conjugados de complexos metalicos e oligonucleotidosInfo
- Publication number
- PT777498E PT777498E PT95925792T PT95925792T PT777498E PT 777498 E PT777498 E PT 777498E PT 95925792 T PT95925792 T PT 95925792T PT 95925792 T PT95925792 T PT 95925792T PT 777498 E PT777498 E PT 777498E
- Authority
- PT
- Portugal
- Prior art keywords
- conjugates
- oligonucleotidated
- complexes
- metallic
- oligonucleotides
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4424922A DE4424922A1 (de) | 1994-07-14 | 1994-07-14 | Konjugate aus Metallkomplexen und Oligonucleotiden, die spezifisch an bestimmte Zielstrukturen binden |
DE19944445078 DE4445078A1 (de) | 1994-12-05 | 1994-12-05 | Konjugate aus Metallkomplexen und Oligonucleotiden, diese enthaltende Mittel, deren Verwendung in der Radiodiagnostik sowie Verfahren zu deren Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
PT777498E true PT777498E (pt) | 2004-09-30 |
Family
ID=25938359
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95925792T PT777498E (pt) | 1994-07-14 | 1995-06-30 | Conjugados de complexos metalicos e oligonucleotidos |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0777498B1 (pt) |
JP (2) | JPH10503182A (pt) |
KR (1) | KR100366525B1 (pt) |
CN (1) | CN1219551C (pt) |
AT (1) | ATE265229T1 (pt) |
AU (1) | AU2979195A (pt) |
CA (1) | CA2194558A1 (pt) |
CZ (1) | CZ295930B6 (pt) |
DE (1) | DE69532958T2 (pt) |
DK (1) | DK0777498T3 (pt) |
ES (1) | ES2220933T3 (pt) |
HU (1) | HU220859B1 (pt) |
IL (1) | IL114237A (pt) |
MX (1) | MX9606443A (pt) |
NO (1) | NO318585B1 (pt) |
NZ (1) | NZ289831A (pt) |
PL (1) | PL318147A1 (pt) |
PT (1) | PT777498E (pt) |
RU (1) | RU2165771C2 (pt) |
SK (1) | SK284598B6 (pt) |
TW (1) | TW502040B (pt) |
UA (1) | UA48140C2 (pt) |
WO (1) | WO1996002274A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000514799A (ja) * | 1996-07-03 | 2000-11-07 | プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | オリゴヌクレオチドリンカーおよび固定化および結合オリゴヌクレオチドを用いる技術 |
US6335437B1 (en) * | 1998-09-07 | 2002-01-01 | Isis Pharmaceuticals, Inc. | Methods for the preparation of conjugated oligomers |
AU2007245599B2 (en) * | 2006-05-03 | 2012-05-10 | Baltic Technology Development, Ltd. | Antisense agents combining strongly bound base - modified oligonucleotide and artificial nuclease |
GB201012418D0 (en) * | 2010-07-23 | 2010-09-08 | Santaris Pharma As | Process |
US10357578B2 (en) | 2014-05-13 | 2019-07-23 | Paul Scherrer Institut | Production of 43SC radionuclide and radiopharmaceuticals thereof for use in positron emission tomography |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5013831A (en) * | 1984-01-30 | 1991-05-07 | Enzo Biochem, Inc. | Detectable molecules, method of preparation and use |
WO1988009152A1 (en) * | 1985-03-19 | 1988-12-01 | Mills Randell L | Apparatus providing diagnosis and selective tissue necrosis |
US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
WO1989000062A1 (en) * | 1987-07-07 | 1989-01-12 | The Cancer Institute Board | Radiotherapy |
US5457183A (en) * | 1989-03-06 | 1995-10-10 | Board Of Regents, The University Of Texas System | Hydroxylated texaphyrins |
US5270163A (en) * | 1990-06-11 | 1993-12-14 | University Research Corporation | Methods for identifying nucleic acid ligands |
EP1493825A3 (en) * | 1990-06-11 | 2005-02-09 | Gilead Sciences, Inc. | Method for producing nucleic acid ligands |
IE914220A1 (en) * | 1990-12-10 | 1992-06-17 | Akzo Nv | Labelled, modified oligonucleotides |
EP0588229A3 (en) * | 1992-09-12 | 1994-06-15 | Hoechst Ag | Macrocyclic chelating agents for the preparation of technetium or rhenium complexes |
-
1995
- 1995-06-20 IL IL11423795A patent/IL114237A/xx not_active IP Right Cessation
- 1995-06-30 KR KR1019970700223A patent/KR100366525B1/ko not_active IP Right Cessation
- 1995-06-30 RU RU97102039/14A patent/RU2165771C2/ru not_active IP Right Cessation
- 1995-06-30 MX MX9606443A patent/MX9606443A/es not_active IP Right Cessation
- 1995-06-30 WO PCT/EP1995/002539 patent/WO1996002274A1/en active IP Right Grant
- 1995-06-30 CA CA002194558A patent/CA2194558A1/en not_active Abandoned
- 1995-06-30 AU AU29791/95A patent/AU2979195A/en not_active Abandoned
- 1995-06-30 JP JP8504630A patent/JPH10503182A/ja not_active Withdrawn
- 1995-06-30 ES ES95925792T patent/ES2220933T3/es not_active Expired - Lifetime
- 1995-06-30 AT AT95925792T patent/ATE265229T1/de not_active IP Right Cessation
- 1995-06-30 CZ CZ1997114A patent/CZ295930B6/cs not_active IP Right Cessation
- 1995-06-30 PT PT95925792T patent/PT777498E/pt unknown
- 1995-06-30 PL PL95318147A patent/PL318147A1/xx unknown
- 1995-06-30 UA UA97020642A patent/UA48140C2/uk unknown
- 1995-06-30 HU HU9700100A patent/HU220859B1/hu not_active IP Right Cessation
- 1995-06-30 NZ NZ289831A patent/NZ289831A/xx not_active IP Right Cessation
- 1995-06-30 DE DE69532958T patent/DE69532958T2/de not_active Expired - Fee Related
- 1995-06-30 EP EP95925792A patent/EP0777498B1/en not_active Expired - Lifetime
- 1995-06-30 DK DK95925792T patent/DK0777498T3/da active
- 1995-06-30 SK SK28-97A patent/SK284598B6/sk not_active IP Right Cessation
- 1995-06-30 CN CNB951940007A patent/CN1219551C/zh not_active Expired - Fee Related
- 1995-10-14 TW TW084110812A patent/TW502040B/zh not_active IP Right Cessation
-
1997
- 1997-01-13 NO NO19970141A patent/NO318585B1/no not_active IP Right Cessation
-
2009
- 2009-06-04 JP JP2009134684A patent/JP2009197024A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR970704471A (ko) | 1997-09-06 |
PL318147A1 (en) | 1997-05-12 |
NO318585B1 (no) | 2005-04-11 |
IL114237A0 (en) | 1995-10-31 |
HU9700100D0 (en) | 1997-02-28 |
MX9606443A (es) | 1997-12-31 |
CZ11497A3 (cs) | 1998-08-12 |
IL114237A (en) | 2000-08-31 |
RU2165771C2 (ru) | 2001-04-27 |
DK0777498T3 (da) | 2004-08-16 |
EP0777498B1 (en) | 2004-04-28 |
SK2897A3 (en) | 1997-09-10 |
UA48140C2 (uk) | 2002-08-15 |
NO970141D0 (no) | 1997-01-13 |
JPH10503182A (ja) | 1998-03-24 |
EP0777498A1 (en) | 1997-06-11 |
SK284598B6 (sk) | 2005-07-01 |
NO970141L (no) | 1997-03-14 |
CZ295930B6 (cs) | 2005-12-14 |
CN1219551C (zh) | 2005-09-21 |
ATE265229T1 (de) | 2004-05-15 |
HUT76329A (en) | 1997-08-28 |
DE69532958T2 (de) | 2009-04-09 |
CN1152879A (zh) | 1997-06-25 |
WO1996002274A1 (en) | 1996-02-01 |
CA2194558A1 (en) | 1996-02-01 |
TW502040B (en) | 2002-09-11 |
KR100366525B1 (ko) | 2003-03-15 |
NZ289831A (en) | 1999-01-28 |
JP2009197024A (ja) | 2009-09-03 |
DE69532958D1 (de) | 2004-06-03 |
ES2220933T3 (es) | 2004-12-16 |
AU2979195A (en) | 1996-02-16 |
HU220859B1 (en) | 2002-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA02010801A (es) | Agentes diagnosticos, de representacion y terapeuticos cationicos asociados con sitios vasculares activados. | |
EP2112165A3 (en) | Methods and compositions for the treatment of glomerulonephritis and other inflammatory diseases | |
ATE228361T1 (de) | Reduzierung der kardiotoxizität von antitumormitteln mit manganverbindungen | |
DK0841949T3 (da) | Anvendelse af saccharid-konjugater | |
PT1258497E (pt) | Conjugados de factor viii e um polimero biocompativel | |
TR200003161T2 (tr) | Poliol-IFN-Beta konjugatları | |
CA2334267A1 (en) | Use of peg-ifn-alpha and ribavirin for the treatment of chronic hepatitis c | |
DE69735901D1 (de) | Verbesseringen an oder in verbindung mit diagnostischen/therapeutischen mitteln | |
DK1242115T3 (da) | Kemisk programmerbar immunitet | |
HUT51594A (en) | Process for production of celates and their complexes containing ortolizating functional groups, compositions containing such active substances and process for production of conjugates consisting of one complex and linked to it antibody or fragment of antibody | |
WO2000013712A3 (en) | Methods and compositions for the prevention or treatment of cancer | |
PT777498E (pt) | Conjugados de complexos metalicos e oligonucleotidos | |
MXPA05006306A (es) | Agentes de direccionamiento antilinfoma con funciones efectoras y de afinidad enlazados a traves de un reactivo trifuncional. | |
WO1996040273A3 (en) | Conjugates of ferrites and oligonucleotides, which bond specifically to certain target structures | |
EP1234585A3 (en) | Methods and compositions for the prevention or treatment of cancer | |
TR200000728T2 (tr) | Kronik hepatit C' nin tedavisinde IFN-alfa ve amantadin kullanımı. | |
WO1998051792A8 (en) | Fac molecules and uses thereof | |
RU94001222A (ru) | Способ лечения воспаленных тканей организма |