[go: up one dir, main page]

PT750672E - Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao. - Google Patents

Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao.

Info

Publication number
PT750672E
PT750672E PT95915743T PT95915743T PT750672E PT 750672 E PT750672 E PT 750672E PT 95915743 T PT95915743 T PT 95915743T PT 95915743 T PT95915743 T PT 95915743T PT 750672 E PT750672 E PT 750672E
Authority
PT
Portugal
Prior art keywords
dna sequences
preparation
metaloproteases
matrical
disclosed
Prior art date
Application number
PT95915743T
Other languages
English (en)
Inventor
Horst Will
Bernd Hinzmann
Original Assignee
Max Delbrueck Centrum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4438838A external-priority patent/DE4438838C1/de
Application filed by Max Delbrueck Centrum filed Critical Max Delbrueck Centrum
Publication of PT750672E publication Critical patent/PT750672E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489Metalloendopeptidases (3.4.24)
    • C12N9/6491Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT95915743T 1994-03-17 1995-03-17 Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao. PT750672E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4409663 1994-03-17
DE4438838A DE4438838C1 (de) 1994-03-17 1994-10-21 DNA-Sequenzen für Matrix-Metallproteasen, ihre Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
PT750672E true PT750672E (pt) 2002-05-31

Family

ID=25934916

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95915743T PT750672E (pt) 1994-03-17 1995-03-17 Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao.

Country Status (8)

Country Link
US (2) US6114159A (pt)
EP (1) EP0750672B1 (pt)
JP (1) JP3802560B2 (pt)
AT (1) ATE209684T1 (pt)
DK (1) DK0750672T3 (pt)
ES (1) ES2168361T3 (pt)
PT (1) PT750672E (pt)
WO (1) WO1995025171A2 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07303482A (ja) 1993-11-30 1995-11-21 Fuji Yakuhin Kogyo Kk 新規なメタロプロテアーゼおよびそれをコードするdna
US6825024B1 (en) 1993-11-30 2004-11-30 Fuji Yakuhin Kogyo Kabushiki Kaisha Metalloproteinase and encoding DNA therefor
US6191255B1 (en) * 1995-07-14 2001-02-20 Fuji Yakuhin Kogyo Kabushiki Kaisha Protein and monoclonal antibody specific thereto
DE19543265A1 (de) * 1995-11-20 1997-06-05 Univ Konstanz Autoantigene und Verfahren zur Diagnose von Autoimmunkrankheiten
WO1997040157A1 (en) * 1996-04-25 1997-10-30 Takeda Chemical Industries, Ltd. Matrix metalloprotease
WO1998040475A1 (en) 1997-03-11 1998-09-17 Abbott Laboratories Human matrix metalloprotease gene, proteins encoded therefrom and methods of using same
US6271014B1 (en) 1998-01-09 2001-08-07 Schering-Plough Mammalian proteinases; related reagents and methods
WO2000018900A1 (fr) * 1998-09-29 2000-04-06 Motoji Seiki Adn codant pour de nouveaux polypeptides
WO2001026671A1 (en) * 1999-10-12 2001-04-19 Smithkline Beecham Corporation Methods of treatment using dual matrix-metalloproteinase-2 and matrix metalloproteinase-9 inhibitors
EP1288297A4 (en) * 2000-05-19 2004-11-17 Daiichi Fine Chem Co Ltd REGULATION OF MT1-MMP ACTIVITY
KR20040101502A (ko) * 2002-04-16 2004-12-02 제넨테크, 인크. 종양의 진단 및 치료 방법 및 이를 위한 조성물
US20070004036A1 (en) * 2005-07-01 2007-01-04 Rodolfo Faudoa Methods and compositions for keratinocyte culture
US20070003541A1 (en) * 2005-07-01 2007-01-04 Rodolfo Faudoa Methods and compositions for therapeutics
US20070128685A1 (en) * 2005-07-01 2007-06-07 Rodolfo Faudoa Methods and compositions for cell culture
ITFI20050178A1 (it) * 2005-08-12 2007-02-13 Protera S R L Uso di metalloproteinasi di matrice, mutate e non, per la preparazione di composizioni farmaceutiche, e metalloproteinasi mutate aventi aumentata stabilita'
WO2007079218A2 (en) 2005-12-30 2007-07-12 Dyax Corp. Metalloproteinase binding proteins
WO2008043309A1 (en) * 2006-09-29 2008-04-17 Accelergy Shanghai R & D Center Co., Ltd. Process and system of preparing ultra pure ionic liquids
JP2011506614A (ja) 2007-12-17 2011-03-03 ダイアックス コーポレーション Mmp−14結合タンパク質を含む、骨溶解性障害を処置するための組成物および方法
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
JP5649589B2 (ja) * 2009-03-06 2015-01-07 ハロザイム インコーポレイテッド マトリックスメタロプロテアーゼ1の温度感受性突然変異体およびその使用
US20130012451A1 (en) * 2009-12-21 2013-01-10 The Research Foundation Of State University Of New York Compositions and methods for inhibiting mmp-9-mediated cell migration
WO2013059439A2 (en) 2011-10-21 2013-04-25 Dyax Corp. Combination therapy comprising an mmp-14 binding protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0685557B1 (en) * 1993-11-30 1998-08-12 Fuji Yakuhin Kogyo Kabushiki Kaisha Novel metalloprotease and dna coding for the same
US5652127A (en) * 1995-06-02 1997-07-29 Genencor International, Inc. Method for liquefying starch

Also Published As

Publication number Publication date
WO1995025171A3 (de) 1996-02-22
US6399348B1 (en) 2002-06-04
EP0750672B1 (de) 2001-11-28
ATE209684T1 (de) 2001-12-15
WO1995025171A2 (de) 1995-09-21
JP3802560B2 (ja) 2006-07-26
US6114159A (en) 2000-09-05
JPH10501962A (ja) 1998-02-24
EP0750672A1 (de) 1997-01-02
ES2168361T3 (es) 2002-06-16
DK0750672T3 (da) 2002-03-18

Similar Documents

Publication Publication Date Title
PT750672E (pt) Sequencias de adn para metaloproteases matriciais, sua preparacao e utilizacao.
DK0910647T3 (da) Human DNase i hyperaktive varianter
DE3856180D1 (de) Nukleinsaürefragmente, die mannose bindende fragmente vom menschlichen mannosebindenden protein kodieren
AU7494701A (en) Nrg-2 nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
EP1067182A8 (en) Secretory protein or membrane protein
ES2141761T3 (es) Secuencias de dna codificantes de nuevos factores de crecimiento/diferenciacion.
BR9908823A (pt) Compostos e processos para terapia e diagnóstico de câncer de pulmão
GR3030811T3 (en) Proteins produced by human lymphocytes, dna sequence coding these proteins, and pharmaceutical and biological uses thereof
MX344216B (es) Productos geneticos expresados de forma diferencial en tumores y su uso.
FI945221A0 (fi) Yhdistelmä-DNA-molekyylejä, jotka koodittavat aminopeptidaasientsyymejä, ja niiden käyttö rokotteiden valmistamiseksi matotartuntoja vastaan
ZA87141B (en) Dna sequences coding for proteins having the biological activity of husi-type i inhibitors,biotechnological methods for the preparation of said proteins and pharmaceutical compositions containing said proteins
GEP20043386B (en) β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same
MX9805158A (es) Adn que codifica una proteina activadora de plasminogeno.
ATE278011T1 (de) Human dnase ii
WO2002000878A3 (fr) Dynamine mitochondriale humaine msp1, ses isoformes msp1-x, et leur utilisation en therapeutique
ATE407944T1 (de) Mit trp-proteinen verwandtes protein mtr1 und dieses codierende dna-sequenz
ATE193324T1 (de) Rekombinante herstellung von laktoperoxidase
DE60120187D1 (de) Verkürztes bard1 protein und dessen diagnostische und therapeutische anwendungen
FI954889A0 (fi) Proteiini, jolla on TPO-aktiviteetti
DE60027419D1 (de) Regulatorische Sequenzen des humanen MCP-1 Gens
AU2002350406A1 (en) Identification of ses-3 (spr-5) in c. elegans and the uses of the same
ATE223227T1 (de) Verwendung von lbp zur sepsistherapie
AU2002314193A1 (en) Identification of ses-1 and the uses of the same
MX9709390A (es) Cistatina e humana.