US20030036092A1
(en)
*
|
1991-11-15 |
2003-02-20 |
Board Of Regents, The University Of Texas System |
Directed evolution of enzymes and antibodies
|
US5866344A
(en)
*
|
1991-11-15 |
1999-02-02 |
Board Of Regents, The University Of Texas System |
Antibody selection methods using cell surface expressed libraries
|
RU2159807C2
(ru)
*
|
1993-02-26 |
2000-11-27 |
Саппоро Бревериз Лтд. |
Гены агглютинации, дрожжи
|
US5766914A
(en)
*
|
1995-01-26 |
1998-06-16 |
Michigan State University |
Method of producing and purifying enzymes
|
WO1997027216A1
(en)
*
|
1996-01-29 |
1997-07-31 |
Georgetown University |
Amplification of response from expressed recombinant protein
|
US6300065B1
(en)
|
1996-05-31 |
2001-10-09 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US6696251B1
(en)
|
1996-05-31 |
2004-02-24 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
EP0879878A1
(en)
*
|
1997-05-23 |
1998-11-25 |
Quest International B.V. |
Beer and similar light-sensitive beverages with increased flavour stability and process for producing them
|
EP0916726A1
(en)
|
1997-11-13 |
1999-05-19 |
Rijksuniversiteit te Groningen |
Attaching substances to micro-organisms
|
US6759243B2
(en)
|
1998-01-20 |
2004-07-06 |
Board Of Trustees Of The University Of Illinois |
High affinity TCR proteins and methods
|
US7390619B1
(en)
|
1998-02-11 |
2008-06-24 |
Maxygen, Inc. |
Optimization of immunomodulatory properties of genetic vaccines
|
EP0954978B1
(en)
*
|
1998-03-12 |
2011-11-30 |
VHsquared Limited |
New products comprising inactivated yeasts or moulds provided with active antibodies
|
ATE535154T1
(de)
|
1998-03-12 |
2011-12-15 |
Vhsquared Ltd |
Produkten die inaktivierte hefen oder schimmel enthalten, die auf ihrer aussenoberfläche aktive antikörper haben
|
ATE431834T1
(de)
*
|
1999-03-25 |
2009-06-15 |
Valtion Teknillinen |
Prozess zur trennung von proteinen
|
US7132273B1
(en)
*
|
2000-07-26 |
2006-11-07 |
Korea Research Institute Of Bioscience And Biotechnology |
Cell wall anchor proteins derived from yeast, genes thereof and cell surface expression systems using the same
|
WO2002046400A2
(en)
*
|
2000-12-08 |
2002-06-13 |
The Board Of Trustees Of The University Of Illinois |
Mutated class ii major histocompatibility proteins
|
AU2002229639A1
(en)
*
|
2000-12-13 |
2002-06-24 |
De Haard, Johannes Joseph Wilhelmus |
Camelidae antibody arrays
|
EP1380592B1
(en)
*
|
2001-04-19 |
2008-12-03 |
Kansai Chemical Engineering Co. Ltd |
Cell surface layer-binding protein and utilization thereof
|
WO2002101026A2
(en)
|
2001-06-11 |
2002-12-19 |
Applied Nanosystems B.V. |
Methods for binding acma-type protein anchor fusions to cell-wall material of micro-organisms
|
EP2093286B1
(en)
*
|
2001-10-01 |
2013-02-27 |
Dyax Corporation |
Multi-chain eukaryotic display vectors and uses thereof
|
WO2003064608A2
(en)
*
|
2002-01-25 |
2003-08-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Surface based translation system
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
US8946387B2
(en)
*
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8193318B2
(en)
*
|
2002-08-14 |
2012-06-05 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8044180B2
(en)
*
|
2002-08-14 |
2011-10-25 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
ATE536188T1
(de)
|
2002-08-14 |
2011-12-15 |
Macrogenics Inc |
Fcgammariib-spezifische antikörper und verfahren zur verwendung davon
|
US8187593B2
(en)
*
|
2002-08-14 |
2012-05-29 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8530627B2
(en)
*
|
2002-08-14 |
2013-09-10 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US7563600B2
(en)
|
2002-09-12 |
2009-07-21 |
Combimatrix Corporation |
Microarray synthesis and assembly of gene-length polynucleotides
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
ES2897506T3
(es)
*
|
2003-01-09 |
2022-03-01 |
Macrogenics Inc |
Identificación y modificación de anticuerpos con regiones Fc variantes y métodos de utilización de los mismos
|
CN101979650B
(zh)
|
2003-10-22 |
2015-09-16 |
凯克研究生院 |
使用单倍体交配策略在酵母中合成异聚多亚基多肽的方法
|
EP2497478A3
(en)
|
2003-12-05 |
2012-11-07 |
Children's Hospital Medical Center |
Oligosaccaride compositions and use thereof in the treatment of infection
|
KR101297146B1
(ko)
|
2004-05-10 |
2013-08-21 |
마크로제닉스, 인크. |
인간화 FcγRIIB 특이적 항체 및 그의 사용 방법
|
WO2007024249A2
(en)
|
2004-11-10 |
2007-03-01 |
Macrogenics, Inc. |
Engineering fc antibody regions to confer effector function
|
US20080003617A1
(en)
*
|
2004-12-20 |
2008-01-03 |
Xiaomin Fan |
Methods for the identification and the isolation of epitope specific antibodies
|
EP1674479A1
(en)
*
|
2004-12-22 |
2006-06-28 |
Memorial Sloan-Kettering Cancer Center |
Modulation of Fc Gamma receptors for optimizing immunotherapy
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
EP3479844B1
(en)
*
|
2005-04-15 |
2023-11-22 |
MacroGenics, Inc. |
Covalent diabodies and uses thereof
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
EP1726650A1
(en)
*
|
2005-05-27 |
2006-11-29 |
Universitätsklinikum Freiburg |
Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
|
EP1893635A4
(en)
*
|
2005-06-17 |
2009-02-25 |
Biorexis Pharmaceutical Corp |
LIBRARIES ANCHORED TRANSFERRINFUSION PROTEINS
|
WO2007009082A1
(en)
*
|
2005-07-12 |
2007-01-18 |
Codon Devices, Inc. |
Compositions and methods for biocatalytic engineering
|
EP1746103A1
(en)
*
|
2005-07-20 |
2007-01-24 |
Applied NanoSystems B.V. |
Bifunctional protein anchors
|
PL1919503T3
(pl)
|
2005-08-10 |
2015-04-30 |
Macrogenics Inc |
Identyfikacja i inżynieria przeciwciał ze zmiennymi regionami FC oraz sposoby ich stosowania
|
EP1999470A4
(en)
*
|
2006-03-10 |
2009-08-19 |
Macrogenics Inc |
IDENTIFICATION AND GENETIC MODIFICATION OF ANTIBODIES WITH HEAVY CHAINS OF VARIANTS AND METHODS OF USE THEREOF
|
US20070231805A1
(en)
*
|
2006-03-31 |
2007-10-04 |
Baynes Brian M |
Nucleic acid assembly optimization using clamped mismatch binding proteins
|
US7786270B2
(en)
*
|
2006-05-26 |
2010-08-31 |
Macrogenics, Inc. |
Humanized FcγRIIB-specific antibodies and methods of use thereof
|
WO2008002933A2
(en)
|
2006-06-26 |
2008-01-03 |
Macrogenics, Inc. |
Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof
|
ES2599319T3
(es)
|
2006-06-26 |
2017-02-01 |
Macrogenics, Inc. |
Anticuerpos específicos de Fc RIIB y métodos de uso de éstos
|
US20080112961A1
(en)
*
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
WO2008140603A2
(en)
|
2006-12-08 |
2008-11-20 |
Macrogenics, Inc. |
METHODS FOR THE TREATMENT OF DISEASE USING IMMUNOGLOBULINS HAVING FC REGIONS WITH ALTERED AFFINITIES FOR FCγR ACTIVATING AND FCγR INHIBITING
|
KR20090098880A
(ko)
|
2006-12-12 |
2009-09-17 |
바이오렉시스 파마슈티칼 코포레이션 |
트랜스페린 융합 단백질 라이브러리
|
US20110076752A1
(en)
*
|
2007-02-09 |
2011-03-31 |
Medimmune, Llc |
Antibody library display by yeast cell plasma membrane
|
WO2008118476A2
(en)
|
2007-03-26 |
2008-10-02 |
Codon Devices, Inc. |
Cell surface display, screening and production of proteins of interest
|
BRPI0816785A2
(pt)
|
2007-09-14 |
2017-05-02 |
Adimab Inc |
bibliotecas de anticorpos sintéticos racionalmente desenhadas, e, usos para as mesmas
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
US8637435B2
(en)
*
|
2007-11-16 |
2014-01-28 |
Merck Sharp & Dohme Corp. |
Eukaryotic cell display systems
|
US8883146B2
(en)
|
2007-11-30 |
2014-11-11 |
Abbvie Inc. |
Protein formulations and methods of making same
|
NZ622583A
(en)
|
2007-11-30 |
2015-08-28 |
Abbvie Biotechnology Ltd |
Protein formulations and methods of making same
|
WO2009117030A2
(en)
|
2007-12-19 |
2009-09-24 |
Macrogenics, Inc. |
Improved compositions for the prevention and treatment of smallpox
|
WO2009111183A1
(en)
|
2008-03-03 |
2009-09-11 |
Glycofi, Inc. |
Surface display of recombinant proteins in lower eukaryotes
|
ITUD20080055A1
(it)
*
|
2008-03-13 |
2009-09-14 |
Transactiva S R L |
Procedimento per la produzione di una proteina umana in pianta, in particolare un enzima lisosomiale umano ricombinante in endosperma di cereali
|
EP3067063A1
(en)
|
2008-04-02 |
2016-09-14 |
MacroGenics, Inc. |
Her2/neu-specific antibodies and methods of using same
|
ES2654937T3
(es)
|
2008-04-02 |
2018-02-15 |
Macrogenics, Inc. |
Anticuerpos específicos para el complejo BCR y procedimientos de uso de los mismos
|
EP2282770B1
(en)
*
|
2008-06-04 |
2018-03-07 |
MacroGenics, Inc. |
Antibodies with altered binding to fcrn and methods of using same
|
US8067339B2
(en)
|
2008-07-09 |
2011-11-29 |
Merck Sharp & Dohme Corp. |
Surface display of whole antibodies in eukaryotes
|
EP2379718B2
(en)
|
2008-12-16 |
2020-12-30 |
Novartis AG |
Yeast display systems
|
PL2486141T3
(pl)
|
2009-10-07 |
2018-07-31 |
Macrogenics, Inc. |
Polipeptydy zawierające regiony fc i mające w wyniku zmian w zakresie fukozylacji ulepszoną funkcję efektorową, i sposoby zastosowania tych polipeptydów
|
PH12018501083A1
(en)
|
2010-03-04 |
2019-02-18 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
BR112013001175A2
(pt)
|
2010-07-16 |
2017-07-04 |
Adimab Llc |
bibliotecas de anticorpos
|
JP5964300B2
(ja)
|
2010-08-02 |
2016-08-03 |
マクロジェニクス,インコーポレーテッド |
共有結合型ダイアボディおよびその使用
|
WO2012105833A1
(en)
|
2011-02-01 |
2012-08-09 |
Bac Ip B.V. |
Antigen-binding protein directed against epitope in the ch1 domain of human igg antibodies
|
EP2710382B1
(en)
|
2011-05-17 |
2017-10-18 |
Bristol-Myers Squibb Company |
Improved methods for the selection of binding proteins
|
ES2605784T3
(es)
|
2011-05-21 |
2017-03-16 |
Macrogenics, Inc. |
Dominios de enlazamiento a suero desinmunizados y su uso para extender la vida media en suero
|
TW201326207A
(zh)
|
2011-10-24 |
2013-07-01 |
Abbvie Inc |
抗tnf免疫結合物
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
DK2968520T3
(da)
|
2013-03-14 |
2021-08-09 |
Macrogenics Inc |
Bispecifikke molekyler som er immunoreaktive med immuneffektorceller der udtrykker en aktiverende receptor
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
CA2963991A1
(en)
|
2014-09-29 |
2016-04-07 |
Duke University |
Bispecific molecules comprising an hiv-1 envelope targeting arm
|
US11136613B2
(en)
|
2015-04-30 |
2021-10-05 |
Board Of Regents, The University Of Texas System |
Antibacterial polypeptide libraries and methods for screening the same
|
IL262396B2
(en)
|
2016-04-15 |
2023-09-01 |
Macrogenics Inc |
New b7-h3 binding molecules, drug-antibody conjugates and their uses
|
WO2018104893A1
(en)
|
2016-12-06 |
2018-06-14 |
Glaxosmithkline Intellectual Property Development Limited |
Alpha4-beta7 antibodies with incrased fcrn binding and/or half-life
|