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PT1224164E - Derivados de acido hidroxamico como inibidor da formacao de cd23 humano soluvel - Google Patents

Derivados de acido hidroxamico como inibidor da formacao de cd23 humano soluvel

Info

Publication number
PT1224164E
PT1224164E PT00975954T PT00975954T PT1224164E PT 1224164 E PT1224164 E PT 1224164E PT 00975954 T PT00975954 T PT 00975954T PT 00975954 T PT00975954 T PT 00975954T PT 1224164 E PT1224164 E PT 1224164E
Authority
PT
Portugal
Prior art keywords
inhibitor
formation
acid derivatives
hydroxamic acid
human soluble
Prior art date
Application number
PT00975954T
Other languages
English (en)
Inventor
Andrew Faller
John Gerard Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of PT1224164E publication Critical patent/PT1224164E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
PT00975954T 1999-10-27 2000-10-25 Derivados de acido hidroxamico como inibidor da formacao de cd23 humano soluvel PT1224164E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9925470.8A GB9925470D0 (en) 1999-10-27 1999-10-27 Novel compounds

Publications (1)

Publication Number Publication Date
PT1224164E true PT1224164E (pt) 2005-04-29

Family

ID=10863507

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00975954T PT1224164E (pt) 1999-10-27 2000-10-25 Derivados de acido hidroxamico como inibidor da formacao de cd23 humano soluvel

Country Status (32)

Country Link
US (2) US6673965B1 (pt)
EP (1) EP1224164B1 (pt)
JP (1) JP3922431B2 (pt)
KR (1) KR20020044578A (pt)
CN (1) CN1182107C (pt)
AR (1) AR026244A1 (pt)
AT (1) ATE284382T1 (pt)
AU (1) AU766072B2 (pt)
BR (1) BR0015082A (pt)
CA (1) CA2389319A1 (pt)
CO (1) CO5261576A1 (pt)
CZ (1) CZ20021424A3 (pt)
DE (1) DE60016622T2 (pt)
DK (1) DK1224164T3 (pt)
ES (1) ES2233474T3 (pt)
GB (1) GB9925470D0 (pt)
GC (1) GC0000142A (pt)
HK (1) HK1049146A1 (pt)
HU (1) HUP0203270A3 (pt)
IL (1) IL149364A0 (pt)
MX (1) MXPA02004228A (pt)
MY (1) MY133601A (pt)
NO (1) NO20021965L (pt)
NZ (1) NZ518566A (pt)
PE (1) PE20010898A1 (pt)
PL (1) PL356524A1 (pt)
PT (1) PT1224164E (pt)
SI (1) SI1224164T1 (pt)
TW (1) TW561141B (pt)
UY (1) UY26416A1 (pt)
WO (1) WO2001030747A1 (pt)
ZA (1) ZA200203255B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5524215B2 (ja) 2008-09-19 2014-06-18 ファイザー・インク 抗菌剤として有用なヒドロキサム酸誘導体
EP2507266B1 (en) 2009-12-01 2015-02-18 Boston Medical Center Corporation TREATMENT OF IgE-MEDIATED DISEASE
PT2512474E (pt) 2009-12-16 2014-12-23 Pfizer Derivados de ácido hidroxâmico n-ligado úteis como agentes antibacterianos
CN104529883A (zh) 2011-03-07 2015-04-22 辉瑞大药厂 可用作抗菌剂的氟吡啶酮衍生物
WO2012137094A1 (en) 2011-04-08 2012-10-11 Pfizer Inc. Isoxazole derivatives useful as antibacterial agents
MX2013011432A (es) 2011-04-08 2013-12-09 Pfizer Derivados de imidazol, pirazol, y triazol utiles como agentes antibacterianos.
EP2525213A1 (en) * 2011-05-16 2012-11-21 Renishaw plc Spectroscopic apparatus and methods for determining components present in a sample

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513331D0 (en) 1995-06-30 1995-09-06 British Biotech Pharm Matrix metalloproteinase inhibitors
GB9813451D0 (en) * 1998-06-22 1998-08-19 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
AU1389501A (en) 2001-05-08
UY26416A1 (es) 2001-05-31
US6673965B1 (en) 2004-01-06
TW561141B (en) 2003-11-11
CO5261576A1 (es) 2003-03-31
MXPA02004228A (es) 2002-10-17
GC0000142A (en) 2005-06-29
MY133601A (en) 2007-11-30
ES2233474T3 (es) 2005-06-16
HK1049146A1 (en) 2003-05-02
PL356524A1 (en) 2004-06-28
CA2389319A1 (en) 2001-05-03
US20040077727A1 (en) 2004-04-22
NO20021965L (no) 2002-06-13
HUP0203270A2 (hu) 2003-02-28
DE60016622D1 (de) 2005-01-13
IL149364A0 (en) 2002-11-10
DE60016622T2 (de) 2005-11-03
EP1224164A1 (en) 2002-07-24
WO2001030747A1 (en) 2001-05-03
NZ518566A (en) 2004-02-27
AR026244A1 (es) 2003-02-05
JP3922431B2 (ja) 2007-05-30
BR0015082A (pt) 2003-04-15
DK1224164T3 (da) 2005-03-29
GB9925470D0 (en) 1999-12-29
JP2003512450A (ja) 2003-04-02
CZ20021424A3 (cs) 2002-09-11
ZA200203255B (en) 2003-03-20
HUP0203270A3 (en) 2003-11-28
CN1182107C (zh) 2004-12-29
PE20010898A1 (es) 2001-10-13
AU766072B2 (en) 2003-10-09
CN1411436A (zh) 2003-04-16
ATE284382T1 (de) 2004-12-15
EP1224164B1 (en) 2004-12-08
KR20020044578A (ko) 2002-06-15
SI1224164T1 (en) 2005-06-30
NO20021965D0 (no) 2002-04-25

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