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PL432971A1 - 6-Methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone and method of producing 6-methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone - Google Patents

6-Methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone and method of producing 6-methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone

Info

Publication number
PL432971A1
PL432971A1 PL432971A PL43297120A PL432971A1 PL 432971 A1 PL432971 A1 PL 432971A1 PL 432971 A PL432971 A PL 432971A PL 43297120 A PL43297120 A PL 43297120A PL 432971 A1 PL432971 A1 PL 432971A1
Authority
PL
Poland
Prior art keywords
methylglucopyranosyl
flavanone
methyl
hours
formula
Prior art date
Application number
PL432971A
Other languages
Polish (pl)
Other versions
PL241535B1 (en
Inventor
Agnieszka Krawczyk-Łebek
Edyta Kostrzewa-Susłow
Monika Dymarska
Tomasz Janeczko
Original Assignee
Uniwersytet Przyrodniczy we Wrocławiu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Przyrodniczy we Wrocławiu filed Critical Uniwersytet Przyrodniczy we Wrocławiu
Priority to PL432971A priority Critical patent/PL241535B1/en
Publication of PL432971A1 publication Critical patent/PL432971A1/en
Publication of PL241535B1 publication Critical patent/PL241535B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Wynalazek polega na tym, że do podłoża odpowiedniego dla grzybów strzępkowych wprowadza się szczep Isaria fumosorosea KCH J2. Po upływie co najmniej 72 godzin do hodowli wprowadza się substrat, którym jest 6-metyloflawanon o wzorze 1, rozpuszczony w rozpuszczalniku organicznym mieszającym się z wodą. Transformację prowadzi się w temperaturze od 20 do 30 stopni Celsjusza, przy ciągłym wstrząsaniu, przez co najmniej 96 godzin. Następnie produkt jakim jest 6-metylo-4'-O-β-D-(4"-O-metyloglukopiranozylo)-flawanon o wzorze 2, ekstrahuje się rozpuszczalnikiem organicznym niemieszającym się z wodą i oczyszcza chromatograficznie.The invention consists in introducing the Isaria fumosorosea KCH J2 strain into a medium suitable for filamentous fungi. After at least 72 hours, the substrate is introduced into the culture, which is 6-methylflavanone of the formula I, dissolved in a water-miscible organic solvent. The transformation is carried out at a temperature of 20 to 30 degrees Celsius with continuous shaking for at least 96 hours. The product 6-methyl-4'-O-β-D- (4 "-O-methylglucopyranosyl) -flavanone of formula II is then extracted with a water-immiscible organic solvent and purified by chromatography.

PL432971A 2020-02-20 2020-02-20 6-Methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone and method of producing 6-methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone PL241535B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL432971A PL241535B1 (en) 2020-02-20 2020-02-20 6-Methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone and method of producing 6-methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL432971A PL241535B1 (en) 2020-02-20 2020-02-20 6-Methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone and method of producing 6-methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone

Publications (2)

Publication Number Publication Date
PL432971A1 true PL432971A1 (en) 2021-08-23
PL241535B1 PL241535B1 (en) 2022-10-17

Family

ID=77561326

Family Applications (1)

Application Number Title Priority Date Filing Date
PL432971A PL241535B1 (en) 2020-02-20 2020-02-20 6-Methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone and method of producing 6-methyl-4'-O-β-D-(4"-O-methylglucopyranosyl)-flavanone

Country Status (1)

Country Link
PL (1) PL241535B1 (en)

Also Published As

Publication number Publication date
PL241535B1 (en) 2022-10-17

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