PL374266A1 - Rekombinowane polipeptydy - Google Patents
Rekombinowane polipeptydyInfo
- Publication number
- PL374266A1 PL374266A1 PL02374266A PL37426602A PL374266A1 PL 374266 A1 PL374266 A1 PL 374266A1 PL 02374266 A PL02374266 A PL 02374266A PL 37426602 A PL37426602 A PL 37426602A PL 374266 A1 PL374266 A1 PL 374266A1
- Authority
- PL
- Poland
- Prior art keywords
- polypeptides
- recombinant polypeptides
- inducing
- domain
- trimers
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 230000001939 inductive effect Effects 0.000 abstract 2
- 239000013638 trimer Substances 0.000 abstract 2
- 230000004927 fusion Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34331501P | 2001-12-21 | 2001-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL374266A1 true PL374266A1 (pl) | 2005-10-03 |
| PL208287B1 PL208287B1 (pl) | 2011-04-29 |
Family
ID=23345581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL374266A PL208287B1 (pl) | 2001-12-21 | 2002-12-20 | Polipeptyd fuzyjny, sposób jego wytwarzania oraz kodujący go kwas nukleinowy, komórka gospodarza, rekombinowany wektor oraz sposób jego konstruowania |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7238499B2 (pl) |
| EP (1) | EP1463755B1 (pl) |
| JP (1) | JP4660092B2 (pl) |
| AT (1) | ATE399180T1 (pl) |
| AU (1) | AU2002359780B2 (pl) |
| CA (1) | CA2470564C (pl) |
| DE (1) | DE60227285D1 (pl) |
| ES (1) | ES2309224T3 (pl) |
| MX (1) | MXPA04005909A (pl) |
| PL (1) | PL208287B1 (pl) |
| WO (1) | WO2003060072A2 (pl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050100548A1 (en) * | 2001-07-24 | 2005-05-12 | Biogen Idec Ma Inc. | BAFF, inhibitors thereof and their use in the modulation of B-cell response |
| US20030095967A1 (en) | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
| WO2003072713A2 (en) * | 2002-02-21 | 2003-09-04 | Biogen Idec Ma Inc. | Use of bcma as an immunoregulatory agent |
| US20070010658A1 (en) * | 2002-10-29 | 2007-01-11 | Holtet Thor L | Trimeric binding proteins for trimeric cytokines |
| WO2006044582A2 (en) | 2004-10-13 | 2006-04-27 | The Washington University | Use of baff to treat sepsis |
| WO2006081516A2 (en) * | 2005-01-28 | 2006-08-03 | Biogen Idec Ma Inc. | USE OF BAFF TO TREAT Th2-MEDIATED CONDITIONS |
| AU2011265482B2 (en) * | 2005-05-06 | 2013-08-29 | Providence Health & Services - Oregon | Trimeric OX40L-immunoglobulin fusion protein and methods of use |
| PL2650020T3 (pl) * | 2005-05-06 | 2017-07-31 | Providence Health & Services - Oregon | Trimeryczne białko fuzyjne OX-4-immunoglobulina i sposoby stosowania |
| US8383774B2 (en) | 2007-07-10 | 2013-02-26 | Apogenix Gmbh | Collectin fusion proteins comprising TNF or trail |
| WO2009059298A2 (en) | 2007-11-01 | 2009-05-07 | Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancinc immune responses to eimeria |
| JP2012507299A (ja) * | 2008-10-31 | 2012-03-29 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｌｉｇｈｔ標的分子およびその使用 |
| WO2013166290A1 (en) | 2012-05-04 | 2013-11-07 | Abbvie Biotherapeutics Inc. | P21 biomarker assay |
| WO2013177386A1 (en) | 2012-05-24 | 2013-11-28 | Abbvie Biotherapeutics Inc. | Biomarkers for predicting response to tweak receptor (tweakr) agonist therapy |
| ES2968398T3 (es) | 2013-02-14 | 2024-05-09 | Univ Arkansas | Composiciones y métodos para potenciar las respuestas inmunitarias a Eimeria o limitar la infección por Eimeria |
| EP3578190A1 (en) | 2013-03-15 | 2019-12-11 | The Board of Trustees of the University of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
| ES2744479T3 (es) * | 2014-04-07 | 2020-02-25 | Lokon Pharma Ab | Agentes medicinales novedosos y usos de los mismos |
| TWI843057B (zh) | 2016-05-03 | 2024-05-21 | 阿肯色州大學董事會 | 包含免疫刺激性及抗原性多肽的酵母菌疫苗載體以及其使用方法 |
| AR108468A1 (es) * | 2016-05-13 | 2018-08-22 | Medimmune Llc | POLIPÉPTIDOS DE FUSIÓN CD40L-Fc Y MÉTODOS DE USO DE LOS MISMOS |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5962406A (en) * | 1991-10-25 | 1999-10-05 | Immunex Corporation | Recombinant soluble CD40 ligand polypeptide and pharmaceutical composition containing the same |
| US5716805A (en) * | 1991-10-25 | 1998-02-10 | Immunex Corporation | Methods of preparing soluble, oligomeric proteins |
| CA2146559A1 (en) * | 1992-10-23 | 1994-05-11 | Melanie K. Spriggs | Methods of preparing soluble, oligomeric proteins |
| GB9409768D0 (en) * | 1994-05-16 | 1994-07-06 | Medical Res Council | Trimerising polypeptides |
| US7056695B2 (en) * | 2000-03-02 | 2006-06-06 | Xencor | TNF-α variants |
-
2002
- 2002-12-20 PL PL374266A patent/PL208287B1/pl unknown
- 2002-12-20 EP EP02794341A patent/EP1463755B1/en not_active Expired - Lifetime
- 2002-12-20 MX MXPA04005909A patent/MXPA04005909A/es active IP Right Grant
- 2002-12-20 AT AT02794341T patent/ATE399180T1/de not_active IP Right Cessation
- 2002-12-20 CA CA2470564A patent/CA2470564C/en not_active Expired - Fee Related
- 2002-12-20 AU AU2002359780A patent/AU2002359780B2/en not_active Ceased
- 2002-12-20 WO PCT/US2002/040913 patent/WO2003060072A2/en active Application Filing
- 2002-12-20 DE DE60227285T patent/DE60227285D1/de not_active Expired - Lifetime
- 2002-12-20 US US10/326,186 patent/US7238499B2/en not_active Expired - Fee Related
- 2002-12-20 ES ES02794341T patent/ES2309224T3/es not_active Expired - Lifetime
- 2002-12-20 JP JP2003560159A patent/JP4660092B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005514061A (ja) | 2005-05-19 |
| US20030119149A1 (en) | 2003-06-26 |
| ATE399180T1 (de) | 2008-07-15 |
| ES2309224T3 (es) | 2008-12-16 |
| AU2002359780B2 (en) | 2009-08-13 |
| US7238499B2 (en) | 2007-07-03 |
| EP1463755A2 (en) | 2004-10-06 |
| PL208287B1 (pl) | 2011-04-29 |
| CA2470564C (en) | 2011-02-22 |
| AU2002359780A1 (en) | 2003-07-30 |
| WO2003060072A3 (en) | 2004-01-15 |
| WO2003060072A2 (en) | 2003-07-24 |
| JP4660092B2 (ja) | 2011-03-30 |
| EP1463755B1 (en) | 2008-06-25 |
| DE60227285D1 (de) | 2008-08-07 |
| CA2470564A1 (en) | 2003-07-24 |
| MXPA04005909A (es) | 2005-05-17 |
| EP1463755A4 (en) | 2005-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RECP | Rectifications of patent specification |