PL3495505T3 - Ocena ilościowa wydajności czapeczki informacyjnego rna - Google Patents
Ocena ilościowa wydajności czapeczki informacyjnego rnaInfo
- Publication number
- PL3495505T3 PL3495505T3 PL18207398.1T PL18207398T PL3495505T3 PL 3495505 T3 PL3495505 T3 PL 3495505T3 PL 18207398 T PL18207398 T PL 18207398T PL 3495505 T3 PL3495505 T3 PL 3495505T3
- Authority
- PL
- Poland
- Prior art keywords
- messenger rna
- quantitative assessment
- cap efficiency
- cap
- efficiency
- Prior art date
Links
- 108020004999 messenger RNA Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784253P | 2013-03-14 | 2013-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3495505T3 true PL3495505T3 (pl) | 2025-01-13 |
Family
ID=50625146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18207398.1T PL3495505T3 (pl) | 2013-03-14 | 2014-03-14 | Ocena ilościowa wydajności czapeczki informacyjnego rna |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10626439B2 (pl) |
| EP (2) | EP2971098B1 (pl) |
| JP (1) | JP2016515216A (pl) |
| CN (1) | CN105209633A (pl) |
| AU (1) | AU2014239264A1 (pl) |
| BR (1) | BR112015022141A2 (pl) |
| CA (1) | CA2903488A1 (pl) |
| DK (1) | DK2971098T3 (pl) |
| EA (1) | EA201591286A1 (pl) |
| ES (2) | ES2997341T3 (pl) |
| HU (1) | HUE069140T2 (pl) |
| MX (1) | MX2015011945A (pl) |
| PL (1) | PL3495505T3 (pl) |
| TR (1) | TR201901396T4 (pl) |
| WO (1) | WO2014152673A1 (pl) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3338765T1 (sl) | 2009-12-01 | 2019-05-31 | Translate Bio, Inc. | Derivat steroida za dostavo MRNA pri humanih genetskih boleznih |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US20140206753A1 (en) | 2011-06-08 | 2014-07-24 | Shire Human Genetic Therapies, Inc. | Lipid nanoparticle compositions and methods for mrna delivery |
| DK2718269T3 (en) | 2011-06-08 | 2018-04-09 | Translate Bio Inc | SPLITLY LIPIDS |
| EP2859102A4 (en) | 2012-06-08 | 2016-05-11 | Shire Human Genetic Therapies | NUCLEASE RESISTANT POLYNUCLEOTIDES AND USES THEREOF |
| DK3467108T3 (da) | 2013-03-14 | 2024-06-10 | Translate Bio Inc | Fremgangsmåder til oprensning af messenger-RNA |
| WO2014152659A1 (en) | 2013-03-14 | 2014-09-25 | Shire Human Genetic Therapies, Inc. | Quantitative assessment for cap efficiency of messenger rna |
| PL3495505T3 (pl) * | 2013-03-14 | 2025-01-13 | Translate Bio, Inc. | Ocena ilościowa wydajności czapeczki informacyjnego rna |
| EP2968586B1 (en) | 2013-03-14 | 2018-07-25 | Translate Bio, Inc. | Cftr mrna compositions and related methods and uses |
| US10077439B2 (en) | 2013-03-15 | 2018-09-18 | Modernatx, Inc. | Removal of DNA fragments in mRNA production process |
| WO2014144767A1 (en) | 2013-03-15 | 2014-09-18 | Moderna Therapeutics, Inc. | Ion exchange purification of mrna |
| EP2971033B8 (en) | 2013-03-15 | 2019-07-10 | ModernaTX, Inc. | Manufacturing methods for production of rna transcripts |
| US11377470B2 (en) | 2013-03-15 | 2022-07-05 | Modernatx, Inc. | Ribonucleic acid purification |
| US10385088B2 (en) | 2013-10-02 | 2019-08-20 | Modernatx, Inc. | Polynucleotide molecules and uses thereof |
| ES2954366T3 (es) | 2013-10-22 | 2023-11-21 | Translate Bio Inc | Terapia de ácido ribonucleico mensajero para la deficiencia de argininosuccinato sintetasa |
| US9522176B2 (en) | 2013-10-22 | 2016-12-20 | Shire Human Genetic Therapies, Inc. | MRNA therapy for phenylketonuria |
| ES2750661T3 (es) | 2014-04-25 | 2020-03-26 | Translate Bio Inc | Métodos para la purificación de ARN mensajero |
| WO2015196128A2 (en) | 2014-06-19 | 2015-12-23 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
| JP2017522028A (ja) | 2014-07-16 | 2017-08-10 | モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． | 環状ポリヌクレオチド |
| SE539096C2 (en) * | 2015-03-18 | 2017-04-04 | C Conjunction Ab | A method, system and software application for providing context based commercial information |
| US11434486B2 (en) | 2015-09-17 | 2022-09-06 | Modernatx, Inc. | Polynucleotides containing a morpholino linker |
| WO2017049275A2 (en) | 2015-09-17 | 2017-03-23 | Moderna Therapeutics, Inc. | Polynucleotides containing a stabilizing tail region |
| DK4104687T5 (da) | 2015-09-21 | 2024-07-22 | Trilink Biotechnologies Llc | Sammensætninger og fremgangsmåder til syntetisering af RNA'er med 5-kappe |
| CN114686548A (zh) | 2015-10-14 | 2022-07-01 | 川斯勒佰尔公司 | 用于增强生产的rna相关酶的修饰 |
| EP3362460A1 (en) * | 2015-10-16 | 2018-08-22 | Modernatx, Inc. | Mrna cap analogs and methods of mrna capping |
| US11866754B2 (en) * | 2015-10-16 | 2024-01-09 | Modernatx, Inc. | Trinucleotide mRNA cap analogs |
| EP3656872A1 (en) * | 2015-12-09 | 2020-05-27 | Novartis AG | Label-free analysis of rna capping efficiency using rnase h, probes and liquid chromatography/mass spectrometry |
| WO2017127750A1 (en) | 2016-01-22 | 2017-07-27 | Modernatx, Inc. | Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof |
| US20190167811A1 (en) | 2016-04-13 | 2019-06-06 | Modernatx, Inc. | Lipid compositions and their uses for intratumoral polynucleotide delivery |
| DK3458083T5 (da) | 2016-05-18 | 2024-10-21 | Modernatx Inc | Polynukleotider, der koder for interleukin-12 (il12), og anvendelser heraf |
| GB201615233D0 (en) * | 2016-09-08 | 2016-10-26 | Bbi Solutions Oem Ltd | Solid Phase Conjugate |
| IL268857B2 (en) | 2017-02-27 | 2024-09-01 | Translate Bio Inc | Methods for purification of messenger rna |
| EP3585892B8 (en) | 2017-02-27 | 2022-07-13 | Translate Bio, Inc. | Methods for purification of messenger rna |
| EP3585417B1 (en) | 2017-02-27 | 2023-02-22 | Translate Bio, Inc. | Method of making a codon-optimized cftr mrna |
| EP3624824B1 (en) | 2017-05-16 | 2024-07-10 | Translate Bio, Inc. | Codon-optimized mrna encoding cftr for use in treating cystic fibrosis |
| US20200131498A1 (en) | 2017-06-14 | 2020-04-30 | Modernatx, Inc. | Polynucleotides encoding methylmalonyl-coa mutase |
| US10034951B1 (en) | 2017-06-21 | 2018-07-31 | New England Biolabs, Inc. | Use of thermostable RNA polymerases to produce RNAs having reduced immunogenicity |
| KR20250028535A (ko) * | 2017-06-30 | 2025-02-28 | 코덱시스, 인코포레이티드 | T7 rna 폴리머라제 변이체 |
| WO2019005539A1 (en) | 2017-06-30 | 2019-01-03 | Codexis, Inc. | T7 POLYMERASE RNA VARIANTS |
| KR20210060480A (ko) | 2018-08-24 | 2021-05-26 | 트랜슬레이트 바이오 인코포레이티드 | 전령 rna의 정제 방법 |
| CN113166737A (zh) * | 2018-10-04 | 2021-07-23 | 新英格兰生物实验室公司 | 提高转录的rna的加帽效率的方法和组合物 |
| US11072808B2 (en) | 2018-10-04 | 2021-07-27 | New England Biolabs, Inc. | Methods and compositions for increasing capping efficiency of transcribed RNA |
| AU2019364545A1 (en) * | 2018-10-26 | 2021-04-29 | Illumina, Inc. | Modulating polymer beads for DNA processing |
| KR20210089648A (ko) | 2018-11-08 | 2021-07-16 | 트랜슬레이트 바이오 인코포레이티드 | 메신저 rna 정제를 위한 방법 및 조성물 |
| CA3120647A1 (en) | 2018-11-21 | 2020-05-28 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of nebulized mrna encoding cftr |
| CA3122645A1 (en) | 2018-12-21 | 2020-06-25 | Curevac Ag | Methods for rna analysis |
| CN113453707A (zh) | 2018-12-21 | 2021-09-28 | 库瑞瓦格股份公司 | 用于疟疾疫苗的rna |
| KR20220029556A (ko) | 2019-05-15 | 2022-03-08 | 트랜슬레이트 바이오 인코포레이티드 | 전령 rna의 정제 방법 |
| WO2020254535A1 (en) | 2019-06-18 | 2020-12-24 | Curevac Ag | Rotavirus mrna vaccine |
| JP2022544412A (ja) | 2019-08-14 | 2022-10-18 | キュアバック アーゲー | 免疫賦活特性が減少したｒｎａ組み合わせおよび組成物 |
| CN112626177A (zh) * | 2019-10-09 | 2021-04-09 | 华中科技大学 | 一种快速定量检测rna加帽效率的方法 |
| IL293571B2 (en) | 2020-02-04 | 2025-01-01 | Curevac Ag | Coronavirus vaccine |
| IL298084A (en) | 2020-05-29 | 2023-01-01 | CureVac SE | Nucleic acid based combination vaccines |
| AU2021296914A1 (en) * | 2020-06-26 | 2023-01-19 | Carisma Therapeutics Inc. | mRNA transfection of immune cells |
| CA3170741A1 (en) | 2020-07-31 | 2022-02-03 | Curevac Ag | Nucleic acid encoded antibody mixtures |
| CN113308503A (zh) * | 2020-08-20 | 2021-08-27 | 深圳市瑞吉生物科技有限公司 | 一种Cap2结构5′帽子类似物及其制备方法和应用 |
| US20240066114A1 (en) | 2020-08-31 | 2024-02-29 | CureVac SE | Multivalent nucleic acid based coronavirus vaccines |
| WO2022137133A1 (en) | 2020-12-22 | 2022-06-30 | Curevac Ag | Rna vaccine against sars-cov-2 variants |
| US20240299309A1 (en) | 2020-12-22 | 2024-09-12 | CureVac SE | Pharmaceutical composition comprising lipid-based carriers encapsulating rna for multidose administration |
| US20240102065A1 (en) | 2021-01-27 | 2024-03-28 | CureVac SE | Method of reducing the immunostimulatory properties of in vitro transcribed rna |
| CN117377491A (zh) | 2021-03-26 | 2024-01-09 | 葛兰素史克生物有限公司 | 免疫原性组合物 |
| WO2022233880A1 (en) | 2021-05-03 | 2022-11-10 | Curevac Ag | Improved nucleic acid sequence for cell type specific expression |
| EP4351777A1 (en) * | 2021-06-07 | 2024-04-17 | The University of Massachusetts | Apparatus and method for continuous production of rna |
| IL309502A (en) | 2021-09-03 | 2024-02-01 | CureVac SE | Novel lipid nanoparticles for delivery of nucleic acids comprising phosphatidylserine |
| CN115260264B (zh) * | 2022-02-28 | 2023-06-09 | 广州市恒诺康医药科技有限公司 | 用于rna加帽的化合物及其应用 |
| JP7642260B2 (ja) | 2022-02-28 | 2025-03-10 | ▲広▼州市恒▲諾▼康医▲薬▼科技有限公司 | Ｒｎａキャッピング用化合物及びその使用 |
| WO2023201161A1 (en) * | 2022-04-15 | 2023-10-19 | Thermo Finnigan Llc | Method for quantitative monitoring of mrna capping efficiency |
| AU2023353931A1 (en) | 2022-09-26 | 2025-03-20 | Glaxosmithkline Biologicals Sa | Influenza virus vaccines |
| US12186389B2 (en) | 2022-10-28 | 2025-01-07 | Glaxosmithkline Biologicals Sa | Nucleic acid base vaccine against emerging SARS-CoV-2 variants |
| WO2024161314A1 (en) * | 2023-01-31 | 2024-08-08 | Seqirus Inc. | Capping assay |
| WO2024160936A1 (en) | 2023-02-03 | 2024-08-08 | Glaxosmithkline Biologicals Sa | Rna formulation |
| GB202302092D0 (en) | 2023-02-14 | 2023-03-29 | Glaxosmithkline Biologicals Sa | Analytical method |
| WO2024223728A1 (en) | 2023-04-27 | 2024-10-31 | Glaxosmithkline Biologicals Sa | Influenza virus vaccines |
| WO2024223724A1 (en) | 2023-04-27 | 2024-10-31 | Glaxosmithkline Biologicals Sa | Influenza virus vaccines |
| CN116640833B (zh) * | 2023-06-01 | 2024-11-26 | 中国医学科学院医学生物学研究所 | 一种利用毛细管电泳技术自动化批量检测mRNA加帽率的方法 |
| CN116426610B (zh) * | 2023-06-08 | 2024-01-05 | 启辰生生物科技(珠海)有限公司 | 一种LC-MS法准确定量mRNA加帽效率的方法 |
| GB202404607D0 (en) | 2024-03-29 | 2024-05-15 | Glaxosmithkline Biologicals Sa | RNA formulation |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| DE3529478A1 (de) | 1985-08-16 | 1987-02-19 | Boehringer Mannheim Gmbh | 7-desaza-2'desoxyguanosin-nukleotide, verfahren zu deren herstellung und deren verwendung zur nukleinsaeure-sequenzierung |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| JPS6412935A (en) | 1987-07-02 | 1989-01-17 | Mitsubishi Electric Corp | Constant-speed travel device for vehicle |
| WO1990011353A1 (en) | 1989-03-24 | 1990-10-04 | Research Corporation Technologies, Inc. | Recombinant alpha-galactosidase, a therapy for fabry disease |
| DE69030172T2 (de) | 1990-01-26 | 1997-06-19 | Immunomedics Inc | Impfstoffe gegen Krebs und Infektionskrankheiten |
| US5356804A (en) | 1990-10-24 | 1994-10-18 | Mount Sinai School Of Medicine Of The City Of New York | Cloning and expression of biologically active human α-galactosidase A |
| DE4140463A1 (de) | 1991-12-09 | 1993-06-17 | Boehringer Mannheim Gmbh | 2'-desoxy-isoguanosin, dessen isostere analoge sowie anwendung derselben |
| US5256555A (en) | 1991-12-20 | 1993-10-26 | Ambion, Inc. | Compositions and methods for increasing the yields of in vitro RNA transcription and other polynucleotide synthetic reactions |
| US6458574B1 (en) | 1996-09-12 | 2002-10-01 | Transkaryotic Therapies, Inc. | Treatment of a α-galactosidase a deficiency |
| US6043060A (en) | 1996-11-18 | 2000-03-28 | Imanishi; Takeshi | Nucleotide analogues |
| JP3756313B2 (ja) | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
| US6143877A (en) | 1997-04-30 | 2000-11-07 | Epoch Pharmaceuticals, Inc. | Oligonucleotides including pyrazolo[3,4-D]pyrimidine bases, bound in double stranded nucleic acids |
| DE69829760T3 (de) | 1997-09-12 | 2016-04-14 | Exiqon A/S | Bi- und tri-zyklische - nukleosid, nukleotid und oligonukleotid-analoga |
| US6127121A (en) | 1998-04-03 | 2000-10-03 | Epoch Pharmaceuticals, Inc. | Oligonucleotides containing pyrazolo[3,4-D]pyrimidines for hybridization and mismatch discrimination |
| ES2272322T3 (es) | 1999-08-30 | 2007-05-01 | Roche Diagnostics Gmbh | Compuestos de 2-azapurina y su utilizacion. |
| US6660845B1 (en) | 1999-11-23 | 2003-12-09 | Epoch Biosciences, Inc. | Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof |
| EP1373874A4 (en) | 2001-01-31 | 2004-03-31 | Univ Texas | METHOD AND APPARATUS FOR CONTAINING MATERIALS IN A MICROUSINE CHEMICAL SENSOR NETWORK |
| US20050053942A1 (en) * | 2002-06-24 | 2005-03-10 | Sakari Kauppinen | Methods and systems for detection and isolation of a nucleotide sequence |
| EP2010659B1 (en) | 2006-04-14 | 2014-06-18 | CellScript, Inc. | Kits and methods for generating 5' capped RNA |
| US8304529B2 (en) | 2006-07-28 | 2012-11-06 | Life Technologies Corporation | Dinucleotide MRNA cap analogs |
| WO2009058911A2 (en) | 2007-10-31 | 2009-05-07 | Applied Biosystems Inc. | Preparation and isolation of 5' capped mrna |
| US20100035249A1 (en) * | 2008-08-05 | 2010-02-11 | Kabushiki Kaisha Dnaform | Rna sequencing and analysis using solid support |
| SI3338765T1 (sl) | 2009-12-01 | 2019-05-31 | Translate Bio, Inc. | Derivat steroida za dostavo MRNA pri humanih genetskih boleznih |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| WO2014152659A1 (en) | 2013-03-14 | 2014-09-25 | Shire Human Genetic Therapies, Inc. | Quantitative assessment for cap efficiency of messenger rna |
| PL3495505T3 (pl) | 2013-03-14 | 2025-01-13 | Translate Bio, Inc. | Ocena ilościowa wydajności czapeczki informacyjnego rna |
| WO2017149139A1 (en) | 2016-03-03 | 2017-09-08 | Curevac Ag | Rna analysis by total hydrolysis |
| KR20210022535A (ko) | 2018-04-25 | 2021-03-03 | 에트리스 게엠베하 | Rna 전달용 지질 기반 제형 |
-
2014
- 2014-03-14 PL PL18207398.1T patent/PL3495505T3/pl unknown
- 2014-03-14 WO PCT/US2014/027602 patent/WO2014152673A1/en active Application Filing
- 2014-03-14 AU AU2014239264A patent/AU2014239264A1/en not_active Withdrawn
- 2014-03-14 ES ES18207398T patent/ES2997341T3/es active Active
- 2014-03-14 JP JP2016502491A patent/JP2016515216A/ja not_active Withdrawn
- 2014-03-14 CN CN201480010108.7A patent/CN105209633A/zh active Pending
- 2014-03-14 BR BR112015022141A patent/BR112015022141A2/pt not_active IP Right Cessation
- 2014-03-14 CA CA2903488A patent/CA2903488A1/en not_active Abandoned
- 2014-03-14 DK DK14720376.4T patent/DK2971098T3/en active
- 2014-03-14 EA EA201591286A patent/EA201591286A1/ru unknown
- 2014-03-14 EP EP14720376.4A patent/EP2971098B1/en active Active
- 2014-03-14 EP EP18207398.1A patent/EP3495505B1/en active Active
- 2014-03-14 ES ES14720376T patent/ES2708562T3/es active Active
- 2014-03-14 TR TR2019/01396T patent/TR201901396T4/tr unknown
- 2014-03-14 US US14/775,844 patent/US10626439B2/en active Active
- 2014-03-14 MX MX2015011945A patent/MX2015011945A/es unknown
- 2014-03-14 HU HUE18207398A patent/HUE069140T2/hu unknown
-
2020
- 2020-01-16 US US16/744,985 patent/US11104934B2/en active Active
-
2021
- 2021-05-19 US US17/325,092 patent/US11920182B2/en active Active
-
2024
- 2024-02-01 US US18/430,247 patent/US20240417774A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3495505C0 (en) | 2024-09-11 |
| DK2971098T3 (en) | 2019-02-18 |
| EP3495505B1 (en) | 2024-09-11 |
| US20240417774A1 (en) | 2024-12-19 |
| US20160002705A1 (en) | 2016-01-07 |
| EA201591286A1 (ru) | 2016-02-29 |
| EP3495505A1 (en) | 2019-06-12 |
| US11104934B2 (en) | 2021-08-31 |
| TR201901396T4 (tr) | 2019-02-21 |
| EP2971098A1 (en) | 2016-01-20 |
| AU2014239264A1 (en) | 2015-08-27 |
| CN105209633A (zh) | 2015-12-30 |
| ES2708562T3 (es) | 2019-04-10 |
| US10626439B2 (en) | 2020-04-21 |
| US20210371900A1 (en) | 2021-12-02 |
| JP2016515216A (ja) | 2016-05-26 |
| MX2015011945A (es) | 2015-12-01 |
| EP2971098B1 (en) | 2018-11-21 |
| BR112015022141A2 (pt) | 2017-08-29 |
| CA2903488A1 (en) | 2014-09-25 |
| ES2997341T3 (en) | 2025-02-17 |
| US11920182B2 (en) | 2024-03-05 |
| WO2014152673A1 (en) | 2014-09-25 |
| US20200318156A1 (en) | 2020-10-08 |
| HUE069140T2 (hu) | 2025-02-28 |
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