PL2316431T3 - Kompozycja w postaci stałego preparatu do stosowania doustnego obejmująca agonistę receptora S1P i alkohol cukrowy - Google Patents

Kompozycja w postaci stałego preparatu do stosowania doustnego obejmująca agonistę receptora S1P i alkohol cukrowy

Info

Publication number: PL2316431T3
Authority: PL; Poland
Prior art keywords: receptor agonist; sugar alcohol; oral composition; solid oral; solid
Prior art date: 2003-04-08

Application number

PL10184951.1T

Other languages

English (en)

Inventor

Tomoyuki Oomura

Madhusudhan Pudipeddi

Alan Edward Royce

Colleen Ruegger

Masaki Sasaki

Tokuhiro Tamura

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-08

Filing date

2004-04-06

Publication date

2016-09-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32326722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2316431(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-04-06 Application filed filed Critical

2016-09-30 Publication of PL2316431T3 publication Critical patent/PL2316431T3/pl

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K9/4841—Filling excipients; Inactive ingredients
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Oil, Petroleum & Natural Gas (AREA)
Physiology (AREA)
Nutrition Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Surgery (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Virology (AREA)
Transplantation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

PL10184951.1T 2003-04-08 2004-04-06 Kompozycja w postaci stałego preparatu do stosowania doustnego obejmująca agonistę receptora S1P i alkohol cukrowy PL2316431T3 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US46121503P	2003-04-08	2003-04-08

Publications (1)

Publication Number	Publication Date
PL2316431T3 true PL2316431T3 (pl)	2016-09-30

Family

ID=32326722

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
PL10184951.1T PL2316431T3 (pl)	2003-04-08	2004-04-06	Kompozycja w postaci stałego preparatu do stosowania doustnego obejmująca agonistę receptora S1P i alkohol cukrowy
PL04725895T PL1613288T3 (pl)	2003-04-08	2004-04-06	Stała kompozycja farmaceutyczna zawierająca agonistę receptora S1P oraz alkohol cukrowy

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
PL04725895T PL1613288T3 (pl)	2003-04-08	2004-04-06	Stała kompozycja farmaceutyczna zawierająca agonistę receptora S1P oraz alkohol cukrowy

Country Status (42)

Country	Link
US (11)	US20060275357A1 (pl)
EP (5)	EP2319502A1 (pl)
JP (3)	JP5495467B2 (pl)
KR (3)	KR101367574B1 (pl)
CN (2)	CN101797241B (pl)
AR (3)	AR043987A1 (pl)
AT (3)	ATE414508T1 (pl)
AU (1)	AU2004228929B2 (pl)
BE (2)	BE1015972A5 (pl)
BR (1)	BRPI0409250B8 (pl)
CA (2)	CA2707750A1 (pl)
CL (2)	CL2004000745A1 (pl)
CY (3)	CY1110260T1 (pl)
DE (4)	DE122011100047I1 (pl)
DK (2)	DK2316431T3 (pl)
EC (1)	ECSP056090A (pl)
ES (3)	ES2320767T3 (pl)
FR (2)	FR2854073B1 (pl)
GB (1)	GB2400318B (pl)
GR (1)	GR1005052B (pl)
HK (3)	HK1071685A1 (pl)
HR (3)	HRP20050886B1 (pl)
HU (2)	HUE028247T2 (pl)
IL (3)	IL170888A (pl)
IS (2)	IS2682B (pl)
IT (1)	ITMI20040682A1 (pl)
LU (1)	LU91867I2 (pl)
MA (1)	MA27729A1 (pl)
MX (1)	MXPA05010860A (pl)
MY (1)	MY141249A (pl)
NO (4)	NO329332B1 (pl)
NZ (3)	NZ592339A (pl)
PE (5)	PE20050396A1 (pl)
PL (2)	PL2316431T3 (pl)
PT (1)	PT1613288E (pl)
RU (5)	RU2358716C2 (pl)
SG (1)	SG175449A1 (pl)
SI (2)	SI2316431T1 (pl)
TN (1)	TNSN05256A1 (pl)
TW (1)	TWI332847B (pl)
WO (1)	WO2004089341A1 (pl)
ZA (1)	ZA200507394B (pl)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0513935A (pt) *	2004-07-30	2008-05-20	Novartis Ag	formulações de compostos de 2-amina-1,3-propanodiol
CN1891212B (zh) *	2005-07-07	2010-10-13	马启明	一种口服制剂及其制备方法
ES2529724T3 (es) *	2005-09-09	2015-02-25	Novartis Ag	Tratamiento de enfermedades autoinmunes
PT2623113T (pt)	2005-11-09	2017-07-14	Onyx Therapeutics Inc	Compostos para inibição de enzimas
TWI389683B (zh) *	2006-02-06	2013-03-21	Kyorin Seiyaku Kk	A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient
MY147832A (en)	2006-06-19	2013-01-31	Onyx Therapeutics Inc	Compounds for enzyme inhibition
GB0612721D0 (en)	2006-06-27	2006-08-09	Novartis Ag	Organic compounds
KR20090057399A (ko) *	2006-09-26	2009-06-05	노파르티스 아게	Ｓ１ｐ 조정제를 포함하는 제약 조성물
EP1923054A1 (en) *	2006-09-26	2008-05-21	Novartis AG	Fast disintegrating pharmaceutical composition comprising an S1P agonist or modulator
EP1905434A1 (en) *	2006-09-26	2008-04-02	Novartis AG	Organic compounds comprising an S1P receptor agonist and their therapeutic use
EP1923055A1 (en) *	2006-09-26	2008-05-21	Novartis AG	Freeze-dried pharmaceutical composition comprising an S1P agonist or modulator
AU2011235934A1 (en) *	2006-09-26	2011-11-03	Novartis Ag	Pharmaceutical compositions comprising an S1P modulator
EP1923058A1 (en) *	2006-09-26	2008-05-21	Novartis AG	Coated pharmaceutical composition comprising an S1P agonist or modulator
WO2008124210A1 (en) *	2007-02-14	2008-10-16	Emory University	Methods and compositions for treating or preventing infection using leukocyte sequestration agents
MY149356A (en)	2007-03-29	2013-08-30	Daiichi Sankyo Co Ltd	Pharmaceutical composition
JP5734656B2 (ja)	2007-10-04	2015-06-17	オニキスセラピューティクス，インク．ＯｎｙｘＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	ペプチドエポキシケトンプロテアーゼ阻害剤結晶及びアミノ酸ケトエポキシドの調製
AU2012216630B2 (en) *	2007-10-12	2015-01-22	Novartis Ag	Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
PL2465492T3 (pl) *	2007-10-12	2015-11-30	Novartis Ag	Mieszaniny zawierające modulatory receptora 1-fosforanu sfingozyny (S1P)
JP5534645B2 (ja) *	2008-01-11	2014-07-02	日医工株式会社	無包装状態において安定性に優れた塩酸サルポグレラート含有経口投与製剤
WO2009099174A1 (ja)	2008-02-07	2009-08-13	Kyorin Pharmaceutical Co., Ltd.	アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤
KR101718639B1 (ko)	2008-03-17	2017-03-21	액테리온 파마슈티칼 리미티드	선별적 ｓ1ｐ₁ 수용체 작동약에 대한 투약 섭생
KR20170081755A (ko)	2008-06-20	2017-07-12	노파르티스 아게	다발성 경화증을 치료하기 위한 소아용 조성물
BRPI0914164B1 (pt) *	2008-06-20	2019-04-30	Merck Patent Gmbh	Comistura para produção de comprimidos de desintegração rápida em um processo de formação de comprimido direto, seus usos, e formulações de comprimido
WO2010025796A1 (en) *	2008-09-04	2010-03-11	Cargill Incorporated	Tabletting of ervthritol
AU2009308516B2 (en)	2008-10-21	2016-08-25	Onyx Therapeutics, Inc.	Combination therapy with peptide epoxyketones
EP2358660A2 (en)	2008-11-11	2011-08-24	Novartis AG	Salts of fingolimod
AU2013100532B4 (en) *	2008-11-11	2013-11-28	Novartis Ag	Crystalline forms of fingolimod HCL
RU2015111229A (ru) *	2008-11-11	2015-11-20	Новартис Аг	Кристаллические формы гидрохлорида финголимода
JP5305421B2 (ja)	2008-12-17	2013-10-02	第一三共株式会社	ジアミン誘導体の製造方法
WO2010082531A1 (ja)	2009-01-13	2010-07-22	第一三共株式会社	活性化血液凝固因子阻害剤
EP2407457B1 (en)	2009-03-10	2015-04-22	Daiichi Sankyo Company, Limited	Process for producing diamine derivative
ES2542237T3 (es)	2009-03-13	2015-08-03	Daiichi Sankyo Company, Limited	Procedimiento de producción de un derivado de diamina ópticamente activo
TWI504598B (zh)	2009-03-20	2015-10-21	Onyx Therapeutics Inc	結晶性三肽環氧酮蛋白酶抑制劑
JPWO2010147169A1 (ja) *	2009-06-18	2012-12-06	第一三共株式会社	溶出性の改善された医薬組成物
US9675566B2 (en)	2009-07-16	2017-06-13	Pathologica Llc	Method of treatment with anti-inflammatory and analgesic compounds which are GI-, renal-, and platelet-sparing
US8853147B2 (en)	2009-11-13	2014-10-07	Onyx Therapeutics, Inc.	Use of peptide epoxyketones for metastasis suppression
MA34133B1 (fr)	2010-03-01	2013-04-03	Onyx Therapeutics Inc	Composes pour inhibiteurs de l'immunoproteasome
CA2793413C (en)	2010-03-19	2015-11-24	Daiichi Sankyo Company, Limited	Crystal form of edoxaban tosylate monohydrate and method of producing same
ES2601884T3 (es)	2010-03-19	2017-02-16	Daiichi Sankyo Company, Limited	Procedimiento para mejorar la capacidad de disolución de un anticoagulante
US20130095177A1 (en) *	2010-04-22	2013-04-18	Ratiopharm Gmbh	Method of preparing an oral dosage form comprising fingolimod
HUE031961T2 (en)	2010-07-02	2017-09-28	Daiichi Sankyo Co Ltd	A method for preparing an optically active salt of diamine derivative
EP2646409A4 (en)	2010-11-25	2015-12-16	Shilpa Medicare Ltd	FINGOLIMODE POLYMORPHS AND METHODS THEREOF
UA114283C2 (uk)	2011-01-07	2017-05-25	Новартіс Аг	Композиції імуносупресантів
DK2665471T3 (en)	2011-01-19	2018-03-19	Pathologica Llc	ORAL PHARMACEUTICAL DOSAGE FORMS WITH MANAGED RELEASE COMPREHENSIVE MGBG
JO3177B1 (ar)	2011-04-01	2018-03-08	Novartis Ag	تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
EP2739272A1 (en)	2011-08-01	2014-06-11	Teva Pharmaceutical Industries Ltd.	Process for preparing pharmaceutical compositions comprising fingolimod
CN103732227B (zh)	2011-08-10	2017-04-12	第一三共株式会社	含有二胺衍生物的药物组合物
WO2013091704A1 (en)	2011-12-22	2013-06-27	Synthon Bv	Pharmaceutical composition comprising fingolimod
RU2482842C1 (ru) *	2012-04-26	2013-05-27	Открытое акционерное общество "Новосибхимфарм"	Фармацевтическая композиция агониста рецептора s1p для лечения демиелинизационных заболеваний (варианты) и способ ее получения
RU2506949C1 (ru) *	2012-06-13	2014-02-20	Открытое акционерное общество "Новосибхимфарм"	Фармацевтическая композиция агониста рецептора s1p для лечения демиелинизационных заболеваний
EP2869820A4 (en)	2012-07-09	2016-02-17	Onyx Therapeutics Inc	PRODRUGS OF PEPTIDEPOXIDE KETONE PROTEASE INHIBITORS
RU2496486C1 (ru) *	2012-07-11	2013-10-27	Александр Васильевич Иващенко	Фармацевтическая композиция с улучшенной сыпучестью, лекарственное средство, способ получения и применение
CN105163730B (zh)	2013-01-08	2018-10-30	帕萨罗杰卡有限公司	用于治疗脱髓鞘疾病的方法和组合物
WO2014141298A2 (en) *	2013-03-11	2014-09-18	Astron Research Limited	Stable pharmaceutical composition of fingolimod
EP2990055B1 (en) *	2013-04-26	2019-06-05	Kyoto University	Composition comprising a sphingosine-1-phosphate receptor 1 agonist for inhibiting formation and/or enlargement of cerebral aneurysm or for shrinking it
ES2770500T3 (es) *	2013-05-13	2020-07-01	Synthon Bv	Composición farmacéutica que comprende fingolimod
EP3027174B1 (en)	2013-07-29	2019-07-24	Aizant Drug Research Solutions Private Limited	Pharmaceutical compositions of fingolimod
RU2530626C1 (ru) *	2013-10-21	2014-10-10	Ооо "Валента-Интеллект"	Фармацевтическая композиция агониста рецептора s1p для лечения демиелинизационных заболеваний
CN106794159A (zh) *	2014-08-22	2017-05-31	广东东阳光药业有限公司	一种芬戈莫德固体组合物及其制备方法
WO2016042493A1 (en) *	2014-09-19	2016-03-24	Aizant Drug Research Pvt. Ltd	Pharmaceutical compositions of fingolimod
US9925138B2 (en)	2015-01-20	2018-03-27	Handa Pharmaceuticals, Llc	Stable solid fingolimod dosage forms
AU2016209466A1 (en) *	2015-01-20	2017-08-10	Handa Pharmaceuticals, Llc	Stable solid fingolimod dosage forms
US20180042895A1 (en)	2015-02-26	2018-02-15	Novartis Ag	Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
RU2577230C1 (ru) *	2015-04-09	2016-03-10	Общество с ограниченной ответственностью "Лонг Шенг Фарма Рус"	Способ получения капсул финголимода гидрохлорида
US9690975B2 (en)	2015-05-28	2017-06-27	Axogen Corporation	Quantitative structural assay of a nerve graft
US11434200B2 (en)	2017-03-09	2022-09-06	Novartis Ag	Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof
WO2018178744A1 (en)	2017-03-29	2018-10-04	Deva Holding Anonim Sirketi	Stable formulations of fingolimod
GR1009654B (el)	2018-08-31	2019-11-18	Φαρματεν Α.Β.Ε.Ε.	Φαρμακευτικο σκευασμα που περιλαμβανει εναν ανοσοτροποποιητικο παραγοντα και μεθοδος για την παρασκευη αυτου
DE102018217334A1 (de) *	2018-10-10	2020-04-16	Harbins Ruhr Bioscience, Inc.	Sphingoid-Base und/oder Wirkstoff zur Verwendung bei der Prophylaxe und/oder Therapie einer viralen Infektion und/oder viralen Infektionskrankheit oder der Desinfektion, Nahrungsmittel/Nahrungsergänzungsmittel, Futtermittel/Futterergänzungsmittel und Pflanzenschutzmittel
JP7503420B2 (ja) *	2020-05-18	2024-06-20	東和薬品株式会社	フィンゴリモドを含む医薬組成物とその製造方法及び安定化方法
US11298412B2 (en)	2020-07-16	2022-04-12	Harbins Ruhr Bioscience, Inc.	Sphingoid compounds for prophylaxis and/or therapy of coronaviridae infection

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7607683A (nl) *	1976-07-12	1978-01-16	Akzo Nv	Werkwijze ter bereiding van nieuwe peptiden en peptide-derivaten en de toepassing hiervan.
US4110332A (en) *	1977-05-05	1978-08-29	Chevron Research Company	1-Triorganostannyl-3-organothio-4-substituted-1,2,4-delta2 -triazolidin-5-ones
US4559153A (en)	1983-10-25	1985-12-17	Phillips Petroleum Company	Metal working lubricant
US5112616A (en) *	1988-11-30	1992-05-12	Schering Corporation	Fast dissolving buccal tablet
JP2841857B2 (ja) *	1990-11-29	1998-12-24	田辺製薬株式会社	長期間安定な経口用医薬製剤
DK0627406T3 (da)	1992-10-21	1999-07-12	Taito Co	2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler
DK0778263T3 (da)	1994-08-22	2002-04-22	Mitsubishi Pharma Corp	Benzenforbindelser og farmaceutisk anvendelse af disse
US6121329A (en)	1995-12-28	2000-09-19	Yoshitomi Pharmaceutical Industries, Ltd.	Topical administration of 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol
JP2002241272A (ja)	1996-07-18	2002-08-28	Mitsubishi Pharma Corp	医薬処方組成物
JPH11209277A (ja) *	1998-01-19	1999-08-03	Yoshitomi Pharmaceut Ind Ltd	医薬組成物
US6476004B1 (en) *	1996-07-18	2002-11-05	Mitsubishi Pharma Corporation	Pharmaceutical composition
GB9624038D0 (en)	1996-11-19	1997-01-08	Sandoz Ltd	Organic compounds
WO1998037875A1 (fr) *	1997-02-27	1998-09-03	Yoshitomi Pharmaceutical Industries, Ltd.	Composition medicamenteuse
IL132208A (en)	1997-04-04	2003-07-31	Mitsubishi Pharma Corp	2-aminopropane-1,3-diol derivatives and pharmaceutical compositions containing the same
JPH1180026A (ja) *	1997-09-02	1999-03-23	Yoshitomi Pharmaceut Ind Ltd	新規免疫抑制剤、その使用方法およびその同定方法
JP3545595B2 (ja)	1998-04-01	2004-07-21	花王株式会社	スフィンゴ糖脂質の製造法
JP4627356B2 (ja) *	1999-06-30	2011-02-09	松森　　昭	ウイルス性心筋炎の予防または治療薬剤
KR20020027463A (ko) *	1999-07-12	2002-04-13	우에노 도시오	스핀고신-1-인산 수용체 아고니스트 또는스핀고신-1-인산을 유효 성분으로서 함유하는 선유화 억제제
MXPA03000397A (es)	2000-07-13	2003-05-27	Sankyo Co	Derivados de aminoalcohol.
CA2421893A1 (en) *	2000-08-31	2002-03-07	Merck And Co., Inc.	Phosphate derivatives as immunoregulatory agents
US6953332B1 (en)	2000-11-28	2005-10-11	St. Jude Medical, Inc.	Mandrel for use in forming valved prostheses having polymer leaflets by dip coating
US7326801B2 (en)	2001-03-26	2008-02-05	Novartis Ag	2-amino-propanol derivatives
US7521192B2 (en) *	2001-04-18	2009-04-21	Rigel Pharmaceuticals, Inc.	EDG: modulators of lymphocyte activation and migration
JP2002316985A (ja)	2001-04-20	2002-10-31	Sankyo Co Ltd	ベンゾチオフェン誘導体
WO2003020313A1 (fr)	2001-09-04	2003-03-13	Ono Pharmaceutical Co., Ltd.	Medicaments contre les maladies respiratoires renfermant un agent de regulation du recepteur de la sphingosine-1-phosphate
DE60235900D1 (de)	2001-09-27	2010-05-20	Kyorin Seiyaku Kk	Osuppressivum
PT1431284E (pt)	2001-09-27	2008-01-21	Kyorin Seiyaku Kk	Derivado de sulfureto de diarilo, um seu sal de adição e imunossupressor
CA2473740A1 (en)	2002-01-18	2003-07-31	David Solow-Cordero	Methods of treating conditions associated with an edg receptor
DE60330047D1 (en)	2002-01-18	2009-12-24	Merck & Co Inc	"n-(benzyl)aminoalkyl carboxylate, phosphinate, phosphonate und tetrazole als edg rezeptoragonisten"
CA2472680A1 (en)	2002-01-18	2003-07-31	Merck & Co., Inc.	Selective s1p1/edg1 receptor agonists
EP1470137B1 (en)	2002-01-18	2009-09-02	Merck & Co., Inc.	Edg receptor agonists
PT1772145E (pt) *	2004-07-16	2011-05-27	Kyorin Seiyaku Kk	Processo de utiliza??o eficaz de um medicamento e processo respeitante ? preven??o de efeitos secund?rios

2004
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Also Published As

Publication number	Publication date
EP2316431B1 (en)	2015-09-30
BRPI0409250B8 (pt)	2022-01-18
EP2008650A2 (en)	2008-12-31
US20220031609A1 (en)	2022-02-03
KR20110005320A (ko)	2011-01-17
CA2521325C (en)	2010-09-14
WO2004089341A1 (en)	2004-10-21
HRP20050886A2 (en)	2006-11-30
FR11C0036I1 (fr)	2011-10-14
GB2400318B (en)	2005-08-10
MA27729A1 (fr)	2006-01-02
FR2854073A1 (fr)	2004-10-29
GB0407819D0 (en)	2004-05-12
CY2011013I2 (el)	2014-04-09
EP1613288A1 (en)	2006-01-11
JP2011006461A (ja)	2011-01-13
AU2004228929A1 (en)	2004-10-21
RU2475236C2 (ru)	2013-02-20
NO2011016I2 (no)	2012-08-27
RU2475237C2 (ru)	2013-02-20
US20190175527A1 (en)	2019-06-13
PE20090743A1 (es)	2009-07-17
BE2011C030I2 (pl)	2023-03-07
PE20150676A1 (es)	2015-05-17
NO329332B1 (no)	2010-09-27
FR2854073B1 (fr)	2008-03-14
RU2012148593A (ru)	2014-05-20
TNSN05256A1 (en)	2007-07-10
AU2004228929B2 (en)	2008-02-07
NO20055231L (no)	2006-01-09
CY1110260T1 (el)	2014-04-09
PE20050396A1 (es)	2005-07-05
RU2358716C2 (ru)	2009-06-20
DK2316431T3 (en)	2016-01-11
GR1005052B (el)	2005-11-30
JP5495467B2 (ja)	2014-05-21
GB2400318A (en)	2004-10-13
MY141249A (en)	2010-03-31
CN101797241B (zh)	2013-03-27
ES2228282B1 (es)	2006-02-16
DE202004021680U1 (de)	2010-04-22
PE20131352A1 (es)	2013-11-14
CL2004000745A1 (es)	2005-02-11
US20140011885A1 (en)	2014-01-09
IL197578A (en)	2015-10-29
US20170290787A1 (en)	2017-10-12
CA2707750A1 (en)	2004-10-21
JP2013177404A (ja)	2013-09-09
AR078781A2 (es)	2011-11-30
NO335120B1 (no)	2014-09-22
NO2011016I1 (no)	2011-09-19
HK1155647A1 (en)	2012-05-25
CY1117071T1 (el)	2017-04-05
NO334116B1 (no)	2013-12-16
MXPA05010860A (es)	2006-05-25
ITMI20040682A1 (it)	2004-07-06
HRP20100600A2 (hr)	2011-03-31
HK1071685A1 (en)	2005-07-29
HRP20100601B1 (hr)	2016-12-02
ES2320767T3 (es)	2009-05-28
IL197578A0 (en)	2011-07-31
IS8885A (is)	2010-02-25
KR20050121712A (ko)	2005-12-27
IL242037A0 (en)	2015-11-30
HUE028247T2 (en)	2016-12-28
HRP20100601A2 (hr)	2011-03-31
RU2010146697A (ru)	2012-05-27
EP1613288B1 (en)	2008-11-19
ES2228282A1 (es)	2005-04-01
US20110105620A1 (en)	2011-05-05
BRPI0409250A (pt)	2006-03-28
ECSP056090A (es)	2006-03-01
SI2316431T1 (sl)	2016-04-29
AT504853A2 (de)	2008-08-15
CN101797241A (zh)	2010-08-11
IS2682B (is)	2010-10-15
EP2319502A1 (en)	2011-05-11
PL1613288T3 (pl)	2009-07-31
US20140255497A1 (en)	2014-09-11
AT501681B1 (de)	2012-04-15
TW200503784A (en)	2005-02-01
NZ586280A (en)	2011-12-22
CA2521325A1 (en)	2004-10-21
US20090203798A1 (en)	2009-08-13
BRPI0409250B1 (pt)	2017-07-11
NO20055231D0 (no)	2005-11-07
BE1015972A5 (fr)	2005-12-06
CL2011000450A1 (es)	2011-11-25
ZA200507394B (en)	2007-03-28
KR20120101148A (ko)	2012-09-12
GR20040100121A (el)	2004-12-17
EP2769713A1 (en)	2014-08-27
US20080311188A1 (en)	2008-12-18
NZ592339A (en)	2012-09-28
TWI332847B (en)	2010-11-11
JP5543298B2 (ja)	2014-07-09
LU91867I2 (fr)	2011-11-08
DE122011100047I1 (de)	2011-12-15
EP2316431A1 (en)	2011-05-04
DE102004016947A1 (de)	2004-10-21
PE20130200A1 (es)	2013-03-09
US20130108675A1 (en)	2013-05-02
US20200237690A1 (en)	2020-07-30
SI1613288T1 (sl)	2009-04-30
HUS1100016I1 (hu)	2016-08-29
CN1767819B (zh)	2010-07-28
EP2008650A3 (en)	2011-04-27
SG175449A1 (en)	2011-11-28
HRP20050886B1 (en)	2011-01-31
HK1091114A1 (en)	2007-01-12
RU2010147000A (ru)	2012-08-10
LU91867I9 (pl)	2019-01-03
FR11C0036I2 (fr)	2023-12-29
KR101367574B1 (ko)	2014-02-25
RU2009105403A (ru)	2010-08-27
IE20040246A1 (en)	2004-12-15
PT1613288E (pt)	2009-02-25
AR078782A2 (es)	2011-11-30
AR043987A1 (es)	2005-08-17
IS8114A (is)	2005-11-01
JP2004307506A (ja)	2004-11-04
ATE414508T1 (de)	2008-12-15
DK1613288T3 (da)	2009-03-23
CY2011013I1 (el)	2014-04-09
NO20100250L (no)	2006-01-09
IL170888A (en)	2010-06-16
NZ542622A (en)	2009-01-31
NO20131287L (no)	2006-01-09
DE602004017847D1 (de)	2009-01-02
CN1767819A (zh)	2006-05-03
US20060275357A1 (en)	2006-12-07
AT501681A1 (de)	2006-10-15
ES2556947T3 (es)	2016-01-21
RU2005134173A (ru)	2006-09-10
US8324283B2 (en)	2012-12-04

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