[go: up one dir, main page]

PH26827A - A locally administrable therapeutic composition for inflammatory disease - Google Patents

A locally administrable therapeutic composition for inflammatory disease Download PDF

Info

Publication number
PH26827A
PH26827A PH38108A PH38108A PH26827A PH 26827 A PH26827 A PH 26827A PH 38108 A PH38108 A PH 38108A PH 38108 A PH38108 A PH 38108A PH 26827 A PH26827 A PH 26827A
Authority
PH
Philippines
Prior art keywords
eye
inflammatory
acid
sodium
salt
Prior art date
Application number
PH38108A
Other languages
English (en)
Inventor
Takahiro Ogawa
Yoshikazu Kuribayashi
Original Assignee
Senju Pharma Co
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11923115&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH26827(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Senju Pharma Co, Robins Co Inc A H filed Critical Senju Pharma Co
Priority to PH42478A priority Critical patent/PH30230A/en
Publication of PH26827A publication Critical patent/PH26827A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH38108A 1988-01-27 1989-01-26 A locally administrable therapeutic composition for inflammatory disease PH26827A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PH42478A PH30230A (en) 1988-01-27 1991-05-20 A locally administrable therapeutic composition for inflammatory disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1668388 1988-01-27

Publications (1)

Publication Number Publication Date
PH26827A true PH26827A (en) 1992-11-05

Family

ID=11923115

Family Applications (1)

Application Number Title Priority Date Filing Date
PH38108A PH26827A (en) 1988-01-27 1989-01-26 A locally administrable therapeutic composition for inflammatory disease

Country Status (12)

Country Link
US (1) US4910225A (fr)
EP (1) EP0326915B1 (fr)
JP (1) JP2683676B2 (fr)
KR (1) KR960005707B1 (fr)
AT (1) ATE80043T1 (fr)
AU (1) AU609932B2 (fr)
CA (1) CA1325382C (fr)
DE (1) DE68902649T2 (fr)
ES (1) ES2052784T3 (fr)
GR (1) GR3005586T3 (fr)
HK (1) HK162895A (fr)
PH (1) PH26827A (fr)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897858A (en) 1994-02-03 1999-04-27 Schering-Plough Healthcare Products, Inc. Nasal spray compositions exhibiting increased retention in the nasal cavity
US5475034A (en) * 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
US5895645A (en) * 1995-01-31 1999-04-20 Bausch & Lomb Incorporated Opthalmic solution for artificial tears
AR020661A1 (es) * 1998-09-30 2002-05-22 Alcon Lab Inc Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento
DE19961307A1 (de) * 1999-12-18 2001-07-12 Krewel Meuselbach Gmbh Medizinprodukt zur Befeuchtung und Reinigung der Nasenschleimhaut
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
AR030346A1 (es) 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes neurodegenerativos de la retina y cabeza de nervio optico
US6646003B2 (en) 2001-04-02 2003-11-11 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders of the posterior segment of the eye using an amide derivative of flurbiprofen or ketorolac
US7030149B2 (en) 2002-04-19 2006-04-18 Allergan, Inc. Combination of brimonidine timolol for topical ophthalmic use
BR0309747A (pt) * 2002-05-03 2005-04-26 Alcon Inc Método para o tratamento de distúrbios vasculares mediados pelo fator de crescimento vascular endotelial
CN100341498C (zh) * 2003-01-21 2007-10-10 千寿制药株式会社 含有2-氨基-3-(4-溴苯甲酰基)苯乙酸的水成液制剂
US20030187072A1 (en) * 2003-02-14 2003-10-02 Kapin Michael A. Method of treating angiogenesis-related disorders
RU2006101150A (ru) * 2003-06-13 2006-06-10 Алькон, Инк. (Ch) Композиции нестероидных противовоспалительных средств для лечения патологического ангиогенеза глаз
PL1683526T3 (pl) * 2003-11-14 2012-09-28 Senju Pharma Co Preparat wodnego roztworu zawierający antybiotyk aminoglikozydowy i bromfenak
FR2876581B1 (fr) * 2004-10-20 2007-05-18 Interpharm Dev Composition bioadhesive a liberation programmee
CA2560559C (fr) * 2004-11-05 2013-07-02 Senju Pharmaceutical Co., Ltd. Gouttes ophtalmiques aqueuses favorisant la penetration intraoculaire
TWI358290B (en) 2004-12-02 2012-02-21 Alcon Inc Topical nepafenac formulations
MX2007014084A (es) * 2005-05-10 2008-02-07 Alcon Inc Suspension oftalmica que comprende un farmaco oftalmico, una poloxamina y un agente ajustador de la tonicidad de glicol, el uso de dicha composicion para la fabricacion de un medicamento para tratar trastornos oftalmicos.
PT1885336E (pt) * 2005-05-10 2009-05-07 Alcon Inc Formulações de suspensão compreendendo um princípio activo, um tensoactivo poloxâmero ou meroxapol e um glicol, sua utilização no fabrico de um medicamento para tratamento de distúrbios oftálmicos
AU2007208054A1 (en) * 2006-01-25 2007-08-02 Aciex Therapeutics, Inc. Formulations and methods for treating dry eye
US20090010850A1 (en) * 2007-05-24 2009-01-08 Ousler Iii George W Formulations and methods for treating dry eye
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
TW200812575A (en) * 2006-04-28 2008-03-16 Alcon Inc Formulations containing amide derivatives of carboxylic acid NSAIDs for topical administration to the eye
US20080153819A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for treating macular edema and pathologic ocular angiogenesis using a neuroprotective agent and a receptor tyrosine kinase inhibitor
US20090105245A1 (en) * 2006-12-21 2009-04-23 Bingaman David P Methods for treating macular edema and ocular angiogenesis using an anti-inflammatory agent and a receptor tyrosine kinase inhibitor
US20080153818A1 (en) * 2006-12-21 2008-06-26 Bingaman David P Methods for preventing inflammation during surgery
UY31058A1 (es) * 2007-05-01 2008-10-31 Alcon Res Ltd Formulaciones de aminoacido n-halogenado con compuestos antiinflamatorios
BRPI0908502A2 (pt) * 2008-02-21 2017-05-23 Ista Pharmaceuticals aines oftálmicos como adjuvantes
US8778999B2 (en) 2009-03-05 2014-07-15 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic compositions
US8299295B2 (en) * 2009-10-15 2012-10-30 Johnson Matthey Public Limited Company Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
GB0919757D0 (en) 2009-11-12 2009-12-30 Johnson Matthey Plc Polymorphs of bromfenac sodium and methods for preparing bromfenac sodium polymorphs
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
WO2012099142A1 (fr) 2011-01-18 2012-07-26 千寿製薬株式会社 Composition liquide aqueuse de bromfénac qui est efficace comme conservateur
KR102140989B1 (ko) 2012-05-03 2020-08-04 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
US10688041B2 (en) 2012-05-03 2020-06-23 Kala Pharmaceuticals, Inc. Compositions and methods utilizing poly(vinyl alcohol) and/or other polymers that aid particle transport in mucus
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
MX358604B (es) 2012-11-19 2018-08-28 Bausch & Lomb Composicion liquida acuosa que contiene acido 2-amino-3-(4-bromobenzoil) fenilacetico.
US9353122B2 (en) 2013-02-15 2016-05-31 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
EP3763710A1 (fr) 2013-02-20 2021-01-13 Kala Pharmaceuticals, Inc. Composés thérapeutiques et leurs utilisations
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US20160143869A1 (en) 2013-06-19 2016-05-26 Sentiss Research Center Stable bromfenac solution
NZ719185A (en) 2013-11-01 2017-11-24 Kala Pharmaceuticals Inc Crystalline forms of therapeutic compounds and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
US20170000889A1 (en) 2013-12-12 2017-01-05 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
CN106404952B (zh) * 2016-08-31 2019-06-11 辰欣佛都药业(汶上)有限公司 一种溴芬酸钠滴眼液有关物质的测定方法
US10392399B2 (en) 2016-09-08 2019-08-27 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
EP3509422A4 (fr) 2016-09-08 2020-05-20 Kala Pharmaceuticals, Inc. Formes cristallines de composés thérapeutiques et leurs utilisations
AU2017324251A1 (en) 2016-09-08 2019-03-21 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
JPWO2019117252A1 (ja) * 2017-12-14 2020-12-17 参天製薬株式会社 2−アミノ−3−(4−ブロモベンゾイル)フェニル酢酸またはその塩を含有する点眼剤
JP2023547828A (ja) 2020-10-29 2023-11-14 テジュン ファーマシューティカル カンパニー リミテッド 眼科用組成物
EP4282403A4 (fr) 2021-01-21 2024-12-18 Taejoon Pharmaceutical Co., Ltd. Composition ophtalmique

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH577461A5 (fr) * 1975-08-13 1976-07-15 Robins Co Inc A H
AU512570B2 (en) * 1975-08-13 1980-10-16 A.H. Robins Company, Incorporated Amino benzophenones
JPS58201710A (ja) * 1982-05-18 1983-11-24 Meiji Seika Kaisha Ltd 口腔内用抗炎症ペ−スト剤
US4568695A (en) * 1983-12-07 1986-02-04 A. H. Robins Company, Incorporated 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor
US4683242A (en) * 1985-10-28 1987-07-28 A. H. Robins Company, Incorporated Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters

Also Published As

Publication number Publication date
EP0326915A1 (fr) 1989-08-09
HK162895A (en) 1995-10-27
JP2683676B2 (ja) 1997-12-03
ES2052784T3 (es) 1994-07-16
ATE80043T1 (de) 1992-09-15
US4910225A (en) 1990-03-20
AU609932B2 (en) 1991-05-09
DE68902649T2 (de) 1993-02-11
JPH02124817A (ja) 1990-05-14
GR3005586T3 (fr) 1993-06-07
DE68902649D1 (de) 1992-10-08
KR890011823A (ko) 1989-08-22
AU2878689A (en) 1989-07-27
KR960005707B1 (ko) 1996-05-01
EP0326915B1 (fr) 1992-09-02
CA1325382C (fr) 1993-12-21

Similar Documents

Publication Publication Date Title
PH26827A (en) A locally administrable therapeutic composition for inflammatory disease
US5110493A (en) Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
NL192821C (nl) Oftalmische oplossing.
JP4234907B2 (ja) 抗炎症点眼剤
HU211972A9 (en) Antiallergic composition for ophthalmic or nasal use
JPH01104023A (ja) 眼用保存製剤およびその製法
JPS6038323A (ja) 眼科用消炎剤
JPH0696521B2 (ja) 眼局所投与用眼圧降下剤
WO1993024121A1 (fr) Medicament pour le glaucome
US10973758B2 (en) Methods of eye treatment using therapeutic compositions containing dipyridamole
JP6320616B1 (ja) 新規眼科用組成物および使用方法
WO2019135779A1 (fr) Nouvelle composition ophtalmique et méthodes d'utilisation
JPS5929616A (ja) 抗炎症眼科用液剤およびその製法
EP0728480A1 (fr) Utilisation d'ifenprodil pour le traitement de la pression intraoculaire élevée
RU2657419C1 (ru) Фармацевтическая композиция для назального применения
US5428030A (en) Method of reducing elevated intraocular pressure
KR950013745B1 (ko) 안과 제제용 방부 시스템
JPH10203979A (ja) チアプロフェン酸を含有する抗眼炎症剤
CN119385935A (zh) 一种不含抑菌剂和增粘剂的美洛昔康溶液型眼用制剂及其制备方法
JPH0778022B2 (ja) 緑内障治療剤
US20180200289A1 (en) Novel ophthalmic composition and methods of use
JPS63201122A (ja) トリフルオロメタンスルホンアミドを含有する緑内障治療配合物
JP2002322060A (ja) 粘膜適用組成物
JPH0797318A (ja) オキシフェドリンを必須成分とする眼圧降下剤
JPH09295935A (ja) 抗眼炎症剤