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PE27597A1 - Metodo para producir l-lisina y acido l-glutamico por fermentacion - Google Patents

Metodo para producir l-lisina y acido l-glutamico por fermentacion

Info

Publication number
PE27597A1
PE27597A1 PE1995276735A PE27673595A PE27597A1 PE 27597 A1 PE27597 A1 PE 27597A1 PE 1995276735 A PE1995276735 A PE 1995276735A PE 27673595 A PE27673595 A PE 27673595A PE 27597 A1 PE27597 A1 PE 27597A1
Authority
PE
Peru
Prior art keywords
glutamic acid
lysine
medium
mutant
producing
Prior art date
Application number
PE1995276735A
Other languages
English (en)
Inventor
Uehara Akinori
Kimura Eiichiro
Inoue Sumio
Kawahara Yoshio
Yoshihara Yasuhiko
Asakura Yoko
Nakamatsu Tsuyoshi
Original Assignee
Suzuki Sanei Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzuki Sanei Co Ltd filed Critical Suzuki Sanei Co Ltd
Publication of PE27597A1 publication Critical patent/PE27597A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/84—Brevibacterium
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/843—Corynebacterium

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

CARACTERIZADO PORQUE COMPRENDE: a) CULTIVAR UNA ESTIRPE MUTANTE EN UN MEDIO LIQUIDO; b) PRODUCIR Y ACUMULAR L-LISINA Y ACIDO L-GLUTAMICO EN EL MEDIO; c) RECOLECTAR ESTOS DESDE EL MEDIO; ESTA ESTIRPE MUTANTE PROVIENE DE UNA BACTERIA CORYNEFORM PRODUCTORA DE ACIDO L-GLUTAMICO, TENIENDO MUTACION PARA PROPORCIONAR LA PRODUCTIVIDAD DE L-LISINA Y MUTACION SENSIBLE A LA TEMPERATURA ANTE UN AGENTE SUPRESOR DE LA ACTIVIDAD DE LA BIOTINA, TAL COMO MONOPALMITATO DE POLIOXIETILENO SORBITANO, Y CAPACIDAD PARA PRODUCIR L-LISINA Y ACIDO L-GLUTAMICO EN AUSENCIA DEL AGENTE SUPRESOR DE BIOTINA, EN UN MEDIO CONTENIENDO EXCESO DE BIOTINA. TAMBIEN SE REFIERE AL METODO PARA PRODUCIR ACIDO L-GLUTAMICO POR FERMENTACION QUE COMPRENDE: a) CULTIVAR UNA ESTIRPE MUTANTE EN UN MEDIO LIQUIDO; b) PRODUCIR Y ACUMULAR ACIDO L-GLUTAMICO EN EL MEDIO; c) RECOLECTAR EL ACIDO L-GLUTAMICO DESDE EL MEDIO; DICHA ESTIRPE MUTANTE PROVIENE DE UNA BACTERIA CORYNEFORM PRODUCTORA DE ACIDO L-GLUTAMICO, QUE TIENE UNA MUTACION SENSIBLE A LA TEMPERATURA ANTE UN AGENTE SUPRESOR DE LA ACCION DE LA BIOTINA TAL COMO MONOPALMITATO DE POLIOXIETILENO SORBITANO Y QUE TIENE CAPACIDAD PARA PRODUCIR ACIDO L- GLUTAMICO EN AUSENCIA DE EL AGENTE SUPRESOR, EN UN MEDIO QUE CONTENGA UNA CANTIDAD EXCESIVA DE BIOTINA
PE1995276735A 1994-08-19 1995-08-18 Metodo para producir l-lisina y acido l-glutamico por fermentacion PE27597A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19546594 1994-08-19

Publications (1)

Publication Number Publication Date
PE27597A1 true PE27597A1 (es) 1997-08-12

Family

ID=16341537

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1995276735A PE27597A1 (es) 1994-08-19 1995-08-18 Metodo para producir l-lisina y acido l-glutamico por fermentacion

Country Status (9)

Country Link
US (1) US5846790A (es)
EP (2) EP0780477B1 (es)
JP (1) JP2926991B2 (es)
CN (1) CN1079836C (es)
BR (1) BR9508730A (es)
DE (2) DE69535643D1 (es)
ES (1) ES2191710T3 (es)
PE (1) PE27597A1 (es)
WO (1) WO1996006180A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1193343A (zh) * 1995-08-23 1998-09-16 味之素株式会社 通过发酵制备l－谷氨酸的方法
GB9620144D0 (en) * 1996-09-27 1996-11-13 Cerestar Holding Bv Process for the production of of glumatic acid and the use of protein hydrolysates in this process
JP3812019B2 (ja) * 1996-11-21 2006-08-23 味の素株式会社 連続発酵によるｌ−グルタミン酸の製造法
US20030077765A1 (en) * 1997-07-09 2003-04-24 Ajinomoto Co. Inc. Temperature-sensitive dtsR gene
WO1999002692A1 (fr) * 1997-07-09 1999-01-21 Ajinomoto Co., Inc. Genes dtsr sensibles a la temperature
DE69938652D1 (de) * 1998-03-06 2008-06-19 Ajinomoto Kk Gen für penicillin-bindendes protein und verfahren zur herstellung von l-glutaminsäure
AU756507B2 (en) * 1998-03-18 2003-01-16 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
DE69942821D1 (de) * 1998-12-18 2010-11-18 Ajinomoto Kk Verfahren zur fermentativen Herstellung von L-Glutaminsäure
JP2003159092A (ja) * 1999-07-02 2003-06-03 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
US6830903B1 (en) 1999-07-23 2004-12-14 Archer-Daniels-Midland Company Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene
KR100575403B1 (ko) * 1999-07-23 2006-05-03 아처 다니엘 미드랜드 캄파니 세포 ｎａｄｐｈ를 증가시켜 ｌ-아미노산을 생산하는 방법
US6984512B1 (en) 1999-08-02 2006-01-10 Archer-Daniels-Midland Company Bacterial strains, methods of preparing the same and use thereof in fermentation processes for L-lysine production
DE60042552D1 (de) * 1999-08-02 2009-08-27 Archer Daniels Midland Co Metabolische manipulation der produktion von aminosäuren
CN1367827A (zh) * 1999-08-02 2002-09-04 阿彻-丹尼尔斯-米德兰公司 突变细菌株的l－赖氨酸生产
JP4427878B2 (ja) * 1999-08-20 2010-03-10 味の素株式会社 析出を伴う発酵法によるｌ−グルタミン酸の製造法
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
US6737262B1 (en) * 2000-07-11 2004-05-18 Robert I. Bolla Animal feed containing polypeptides
JP2008511318A (ja) * 2004-09-01 2008-04-17 アグロテクノロジー アンド フード イノベイションズ ビー．ブイ． 基質の変換効率が向上された発酵方法
DE102005017508A1 (de) * 2005-04-15 2006-10-19 Basf Ag Verfahren zur Gewinnung einer basischen Aminosäure aus einer Fermentationsbrühe II
JPWO2007024010A1 (ja) * 2005-08-26 2009-03-05 味の素株式会社 Ｌ−グルタミン酸生産菌及びｌ−グルタミン酸の製造方法
JP2010088301A (ja) 2007-02-01 2010-04-22 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
WO2008133161A1 (ja) 2007-04-17 2008-11-06 Ajinomoto Co., Inc. カルボキシル基を有する酸性物質の製造法
CN103088081B (zh) * 2013-02-06 2014-12-03 中粮生化能源（龙江）有限公司 一种补加生物素的生产谷氨酸的发酵方法
CN113444655B (zh) * 2020-03-26 2023-05-16 吉林中粮生化有限公司 谷氨酸棒状杆菌、高谷氨酸产量的温度敏感型菌株及其获得方法、应用以及谷氨酸发酵方法
CN113292758B (zh) * 2021-05-25 2022-06-21 南京工业大学 一种同时具有电和温度响应的形状记忆复合材料及其制备方法和在固定化细胞中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5224593B2 (es) * 1973-10-17 1977-07-01
JPS561889A (en) * 1979-06-20 1981-01-10 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS57102193A (en) * 1980-12-17 1982-06-25 Kyowa Hakko Kogyo Co Ltd Preparation of l-glutamic acid
FR2590592B1 (fr) * 1985-11-26 1989-12-22 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour une enzyme catalysant une reaction dans le cycle tca et adn recombinant le contenant.
JPS62201585A (ja) * 1985-11-26 1987-09-05 Asahi Chem Ind Co Ltd クエン酸合成酵素産生遺伝子を含むｄｎａ断片
JPS6244171A (ja) * 1986-08-07 1987-02-26 Kyowa Hakko Kogyo Co Ltd Ｌ−グルタミン酸生産性新規微生物
JP2578463B2 (ja) * 1988-02-03 1997-02-05 協和醗酵工業株式会社 発酵法によるｌ−リジンの製造法
JPH029384A (ja) * 1988-06-28 1990-01-12 Kyowa Hakko Kogyo Co Ltd 発酵法によるｌ−グルタミン酸の製造方法
JP3245881B2 (ja) * 1990-02-15 2002-01-15 味の素株式会社 塩基性アミノ酸と酸性アミノ酸の同時発酵法
KR0130196B1 (ko) * 1990-02-15 1998-04-03 도바 다다스 염기성 아미노산과 산성 아미노산의 동시 발효법

Also Published As

Publication number Publication date
EP0780477A4 (en) 1999-06-30
DE69535643D1 (de) 2007-12-27
EP1293560A2 (en) 2003-03-19
BR9508730A (pt) 1997-10-21
WO1996006180A1 (fr) 1996-02-29
DE69530306D1 (de) 2003-05-15
EP0780477B1 (en) 2003-04-09
EP0780477A1 (en) 1997-06-25
EP1293560A3 (en) 2004-12-01
EP1293560B1 (en) 2007-11-14
CN1161059A (zh) 1997-10-01
CN1079836C (zh) 2002-02-27
DE69530306T2 (de) 2003-12-11
US5846790A (en) 1998-12-08
ES2191710T3 (es) 2003-09-16
JP2926991B2 (ja) 1999-07-28

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