[go: up one dir, main page]

NO904712D0 - Nanbh diagnostiske midler og vaksiner. - Google Patents

Nanbh diagnostiske midler og vaksiner.

Info

Publication number
NO904712D0
NO904712D0 NO1990904712A NO904712A NO904712D0 NO 904712 D0 NO904712 D0 NO 904712D0 NO 1990904712 A NO1990904712 A NO 1990904712A NO 904712 A NO904712 A NO 904712A NO 904712 D0 NO904712 D0 NO 904712D0
Authority
NO
Norway
Prior art keywords
hcv
genome
nanbh
vaccines
polyprotein
Prior art date
Application number
NO1990904712A
Other languages
English (en)
Other versions
NO303941B1 (no
NO904712L (no
Inventor
Michael Houghton
Qui-Lim Choo
George Kuo
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27406397&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO904712(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of NO904712D0 publication Critical patent/NO904712D0/no
Publication of NO904712L publication Critical patent/NO904712L/no
Priority to NO960741A priority Critical patent/NO304656B1/no
Priority to NO960741A priority patent/NO304654B1/no
Publication of NO303941B1 publication Critical patent/NO303941B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO904712A 1989-03-17 1990-10-30 Vesentlig isolert polypeptid for anvendelse ved detektering av antistoff mot HCV in vitro og i en in vitro immuno analyse, immunoanalysett og antistoff sammensetning NO303941B1 (no)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NO960741A NO304656B1 (no) 1989-03-17 1996-02-23 Polynukleotid i vesentlig isolert form, analysesett, polymerase kjedereaksj
NO960741A NO304654B1 (no) 1989-03-17 1996-02-23 Fremgangsmaate for fremstilling av et terapeutisk aktivt polypeptid, rekombinant vektor og vertscelle

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32533889A 1989-03-17 1989-03-17
US34133489A 1989-04-20 1989-04-20
US35500289A 1989-05-18 1989-05-18
PCT/US1990/001348 WO1990011089A1 (en) 1989-03-17 1990-03-15 Nanbv diagnostics and vaccines

Publications (3)

Publication Number Publication Date
NO904712D0 true NO904712D0 (no) 1990-10-30
NO904712L NO904712L (no) 1990-10-30
NO303941B1 NO303941B1 (no) 1998-09-28

Family

ID=27406397

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904712A NO303941B1 (no) 1989-03-17 1990-10-30 Vesentlig isolert polypeptid for anvendelse ved detektering av antistoff mot HCV in vitro og i en in vitro immuno analyse, immunoanalysett og antistoff sammensetning

Country Status (19)

Country Link
EP (3) EP1034785A3 (no)
JP (13) JP2656995B2 (no)
KR (2) KR0185373B1 (no)
AT (1) ATE286979T1 (no)
AU (3) AU666767B2 (no)
CA (1) CA2012482C (no)
DE (3) DE388232T1 (no)
DK (1) DK0388232T3 (no)
ES (2) ES2228297T1 (no)
FI (3) FI106211B (no)
GR (1) GR910300016T1 (no)
HU (3) HUT54896A (no)
IE (2) IE20060608A1 (no)
IL (1) IL93764A (no)
MY (1) MY110260A (no)
NO (1) NO303941B1 (no)
PT (1) PT93480B (no)
UA (1) UA50829C2 (no)
WO (1) WO1990011089A1 (no)

Families Citing this family (181)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523215A (en) * 1985-03-28 1996-06-04 Chiron Corporation Enhanced purification and expression of insoluble recombinant proteins
US5698390A (en) * 1987-11-18 1997-12-16 Chiron Corporation Hepatitis C immunoassays
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
US6861212B1 (en) 1987-11-18 2005-03-01 Chiron Corporation NANBV diagnostics and vaccines
US5714596A (en) * 1987-11-18 1998-02-03 Chiron Corporation NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus
US6171782B1 (en) 1987-11-18 2001-01-09 Chiron Corporation Antibody compositions to HCV and uses thereof
US5712088A (en) * 1987-11-18 1998-01-27 Chiron Corporation Methods for detecting Hepatitis C virus using polynucleotides specific for same
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
US6027729A (en) * 1989-04-20 2000-02-22 Chiron Corporation NANBV Diagnostics and vaccines
DK0398748T3 (da) * 1989-05-18 2002-03-18 Chiron Corp NANBV-diagnostika: polynukleotider anvendelige til screening for hepatitis C virus
EP0416725A3 (en) * 1989-07-14 1991-03-20 Chugai Seiyaku Kabushiki Kaisha Blood-borne non-a, non-b hepatitis specific protein, dna encoding it, and process for its production
WO1991004262A1 (en) * 1989-09-15 1991-04-04 National Institute Of Health Of Japan New hcv isolates
US5372928A (en) * 1989-09-15 1994-12-13 Chiron Corporation Hepatitis C virus isolates
AU642942B2 (en) 1989-12-18 1993-11-04 Wellcome Foundation Limited, The Viral agent
US7166287B1 (en) 1989-12-18 2007-01-23 Glaxo Wellcome Inc. Viral agent
US5308750A (en) * 1989-12-22 1994-05-03 Abbott Laboratories Monoclonal antibodies to putative HCV E2/NS1 proteins and methods for using same
CA2032907C (en) * 1989-12-22 2002-05-14 Richard R. Lesniewski Hepatitis c assay
EP0435229A1 (en) * 1989-12-27 1991-07-03 Sanwa Kagaku Kenkyusho Co., Ltd. DNA of non-A, non-B hepatitis virus gene, its clone and use thereof
KR940000755B1 (ko) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Hcv에 대한 항체 검출, hcv 감염의 진단 및 백신으로서의 그 예방에 특히 적합한 합성 펩티드
US5747239A (en) * 1990-02-16 1998-05-05 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and preventions thereof as vaccines
US5106726A (en) * 1990-02-16 1992-04-21 United Biomedical, Inc. Synthetic peptides specific for the detection of antibodies to HCV
US5582968A (en) * 1990-02-16 1996-12-10 United Biomedical, Inc. Branched hybrid and cluster peptides effective in diagnosing and detecting non-A, non-B hepatitis
KR100206150B1 (ko) † 1990-04-04 1999-07-01 로버트 피. 블랙버언 항-에이치씨브이 항체에 대한 면역분석용 씨형 간염 바이러스(에이치디브이)항원의 조합체
ATE270326T1 (de) * 1990-04-04 2004-07-15 Chiron Corp Protease von hepatitis-c-virus
AU7679491A (en) * 1990-04-04 1991-10-30 Protos, Inc. Hepatitis c virus protease inhibitors
ES2152922T3 (es) * 1990-04-06 2001-02-16 Genelabs Tech Inc Epitopos del virus de la hepatitis c.
CA2044296A1 (en) * 1990-06-12 1991-12-13 Hiroaki Okamoto Oligonucleotide primers, and their application for high-fidelity detection of non-a, non-b hepatitis virus
JP3050395B2 (ja) * 1990-06-12 2000-06-12 国立感染症研究所長 Ｃ型肝炎ウイルス抗原ポリペプチド、その産生方法および抗体の検出方法
EP0933426A1 (en) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-a, non-b hepatitis virus genomic cdna fragments and antigen polypeptides
US5747339A (en) 1990-06-25 1998-05-05 Research Foundation For Microbial Diseases Of Osaka Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide
FI913068A (fi) * 1990-06-25 1991-12-26 Univ Osaka Res Found Non-a-, non-b-hepatitisviruspartiklar.
US5620843A (en) * 1990-06-30 1997-04-15 Akzo Nobel N.V. Non-A non-B sequences
EP0468657A3 (en) * 1990-07-09 1992-02-05 Tonen Corporation Non-a non b hepatitis-specific antigen and its use in hepatitus diagnosis
ATE150086T1 (de) * 1990-07-11 1997-03-15 Shionogi & Co Cdns-sequenz und detektion des hepatitis c-virus
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
JP2714255B2 (ja) * 1990-08-10 1998-02-16 カイロン コーポレイション Ｎａｎｂｖ診断法：ｃ型肝炎ウイルスのスクリーニングに有用なポリヌクレオチド
JP3114731B2 (ja) * 1990-08-14 2000-12-04 国立感染症研究所長 Ｃ型肝炎ウイルス抗体検出用ペプチド抗原及びその使用方法
CA2049679C (en) * 1990-08-24 2005-06-21 Sushil G. Devare Hepatitis c assay utilizing recombinant antigens
US6172189B1 (en) * 1990-08-24 2001-01-09 Abbott Laboratories Hepatitis C assay utilizing recombinant antigens
KR930702365A (ko) * 1990-08-25 1993-09-08 존 더블유. 아담슨 비-a형, 비-b형 간염 바이러스 항원, 진단 방법 및 백신
US7863008B2 (en) 1990-08-25 2011-01-04 Bioprocess Pty Ltd. Method for detecting NANBV associated seroconversion
DE69106998T2 (de) * 1990-10-05 1995-05-24 Akzo Nobel Nv Mit Antikörper gegen Hepatitis-Virus non-A, non-B immunochemisch reagierende Peptide.
DK0770679T4 (da) * 1990-11-03 2010-05-10 Siemens Healthcare Diagnostics HCV-specifikke peptider, sammensætninger dertil og anvendelse deraf
US5753430A (en) * 1990-11-07 1998-05-19 Abbott Laboratories Monoclonal antibodies to hepatitis C virus and method for using same
AU662503B2 (en) * 1990-11-07 1995-09-07 Abbott Laboratories Monoclonal antibodies to hepatitis C virus and method for using same
ES2314334T3 (es) * 1990-11-08 2009-03-16 Novartis Vaccines And Diagnostics, Inc. Asialoglicoproteinas del virus de la hepatitis c.
EP0485209A1 (en) * 1990-11-08 1992-05-13 Immuno Japan Inc. Non A, non B hepatitis virus related antigen, antibody detection systems, polynucleotides and polypeptides
EP0842947B2 (en) * 1990-11-08 2009-03-18 Novartis Vaccines and Diagnostics, Inc. Hepatitis C virus asialoglycoproteins
US6274148B1 (en) 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
JP2945759B2 (ja) 1990-11-08 1999-09-06 カイロン コーポレイション Ｃ型肝炎ウイルスアシアロ糖タンパク質
EP0516859A1 (en) * 1990-11-29 1992-12-09 Toray Industries, Inc. Non-a non-b hepatitis virus antigen protein
CA2056646A1 (en) * 1990-11-29 1992-05-30 Shunji Mishiro Non-a, non-b hepatitis related nucleic acids, antigens, antibodies and their detection reagents
DK0754704T3 (da) * 1990-12-14 2000-04-03 Innogenetics Nv Syntetiske antigener til påvisning af antistoffer mod hepatitis c-virus
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
DE4041304A1 (de) * 1990-12-21 1992-06-25 Mikrogen Molekularbiol Entw Von strukturproteinen des hepatitis c-virus abgeleitete polypeptide, testkits, die diese polypeptide enthalten und impfstoffe gegen infektionen von hepatitis c-viren
KR930703361A (ko) * 1991-01-31 1993-11-29 찰스 엠. 브룩 추정의 c형 간염 바이러스(hcv) 외막 영역에 대한 모노클로날 항체 및 이의 사용 방법
DE69200512T2 (de) * 1991-03-01 1995-03-09 Akzo Nv Mit Antikörper gegen Hepatitis non-A, non-B-Virus immunochemische reaktive Peptide.
ES2098511T3 (es) * 1991-03-26 1997-05-01 Dade Int Inc Procedimiento de diagnosis de hepatitis no-a no-b.
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
EP0510952A1 (en) * 1991-04-26 1992-10-28 Immuno Japan Inc. Oligonucleotide primers and their application for high-fidelity detection of non-a, non-b hepatitis virus
US6190864B1 (en) 1991-05-08 2001-02-20 Chiron Corporation HCV genomic sequences for diagnostics and therapeutics
PL169880B1 (pl) * 1991-05-08 1996-09-30 Chiron Corp Sposób wytwarzania produktu hybrydyzacji z kwasem nukleinowym wirusa zapalenia watroby C PL PL PL
FR2677372B1 (fr) 1991-06-06 1994-11-10 Pasteur Institut Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.
BR9206131A (pt) * 1991-06-10 1995-05-02 Lucky Ltd Hepatite C: diagnóstico e vacinas
CA2070952A1 (en) * 1991-06-11 1992-12-12 Makoto Seki Gene of hepatitis c virus or fragment thereof, polypeptide encoded by the same
JP3350729B2 (ja) * 1991-06-13 2002-11-25 デイド、ベーリング、インコーポレイテッド 非ａ非ｂ肝炎のためのイムノアッセイ
JP3516681B2 (ja) * 1991-06-24 2004-04-05 カイロン コーポレイション Ｃ型肝炎ウイルス（ｈｃｖ）ポリペプチド
IT1249685B (it) * 1991-07-19 1995-03-09 Sorin Biomedica Spa Medoto per la rivelazione di anticorpi contro il virus dell'epatite c e corredi per la sua realizzazione
IT1249684B (it) * 1991-07-19 1995-03-09 Sorin Biomedica Spa Epitopi della proteina env del virus dell'epatite c.
CA2116026C (en) * 1991-08-21 2004-11-23 Suresh M. Desai Hepatitis c assay utilizing recombinant antigens to c-100 region
WO1993004084A1 (en) * 1991-08-21 1993-03-04 Abbott Laboratories Monoclonal antibodies to putative hcv ns5 proteins and methos for using same
EP0600000A4 (en) * 1991-08-21 1995-03-01 Abbott Lab HEPATITIS C DETECTION TEST USING RECOMBINANT ANTIGENS OF THE NS5 REGION.
AU2513592A (en) * 1991-08-21 1993-03-16 Abbott Laboratories Hepatitis c assay utilizing recombinant antigens to ns1
ES2198514T3 (es) * 1991-08-27 2004-02-01 F. Hoffmann-La Roche Ag Cebadores y sondas para la deteccion de la hepatitis c.
EP0532258A2 (en) * 1991-09-09 1993-03-17 Immuno Japan Inc. Oligonucleotides and determination system of HCV genotypes
ATE228564T1 (de) * 1991-09-13 2002-12-15 Chiron Corp Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden
ATE191792T1 (de) † 1991-09-16 2000-04-15 Abbott Lab Verfahren zur detektion von hepatitis c
WO1993006488A1 (en) * 1991-09-16 1993-04-01 Genelabs Technologies, Inc. Peptide based hepatitis c virus immunoassays
ZA927243B (en) * 1991-10-07 1994-01-26 Akzo Nv Non-A, Non-B peptides
JP3158177B2 (ja) * 1991-10-08 2001-04-23 国立感染症研究所長 Ｃ型肝炎診断薬
ZA927837B (en) * 1991-10-15 1994-03-11 Akzo Nv Monoclonal antibodiesto hepatitis C virus
AU3063992A (en) * 1991-11-07 1993-06-07 Dade International Inc. Epitope mapping ot the c33c region of hcv
JP3688290B2 (ja) * 1991-11-21 2005-08-24 コモン サーヴィシス エージェンシー Ｃ型肝炎ウイルス検査
WO1993011158A2 (en) * 1991-12-06 1993-06-10 Akzo Nobel N.V. Non-a, non-b peptides
US5811246A (en) * 1991-12-17 1998-09-22 The Research Foundation Of State University Of New York Process for immobilization onto the surfaces of ELISA plates of a compound carrier complex and for immunization
JP3439209B2 (ja) * 1992-01-31 2003-08-25 アボツト・ラボラトリーズ Ｈｃｖ蛋白のための哺乳動物発現システム
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
EP0589004B2 (en) 1992-03-06 2004-05-06 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes of hcv
US5866139A (en) * 1992-06-04 1999-02-02 Institut Pasteur Nucleotide and peptide sequences of a hepatitis C virus isolate, diagnostic and therapeutic applications
JPH05344899A (ja) * 1992-06-11 1993-12-27 Kokuritsu Yobou Eisei Kenkyusho Ｃ型肝炎ウイルス外被タンパク質の産生法
UA39944C2 (uk) 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
KR100317509B1 (ko) 1992-07-16 2002-02-20 야스모토 토루 C형간염바이러스를분류하기위한항원성펩티드,이펩티드를포함하는키트및이펩티드를사용하는c형간염바이러스를분류하는방법
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
JPH06311885A (ja) * 1992-08-25 1994-11-08 Mitsubishi Kasei Corp Ｃ型肝炎ウイルス遺伝子に相補的なアンチセンス化合物
DE69330372T2 (de) * 1992-09-10 2002-03-14 Isis Pharmaceuticals, Inc. ZUSAMMENSETZUNGEN UND VERFAHREN FüR DIE BEHANDLUNG VON MIT HEPATITIS C VIREN ASSOZIIERTEN KRANKHEITEN
US6423489B1 (en) * 1992-09-10 2002-07-23 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of Hepatitis C virus-associated diseases
US5922857A (en) * 1992-09-28 1999-07-13 Chiron Corporation Methods and compositions for controlling translation of HCV proteins
ES2256837T3 (es) * 1992-09-28 2006-07-16 Chiron Corporation Procedimientos y composiciones para el control de la traduccion de las proteinas del vch.
AU5142393A (en) * 1992-09-29 1994-04-26 Cedars-Sinai Medical Center One step rna and combined one step rna and dna polymerase chain reaction for detection of rare rna or rna and dna
JPH06153959A (ja) * 1992-10-16 1994-06-03 Evernew Biotec Inc Ｃ型肝炎ウィルスの非構造タンパク質及びそれを用いての診断方法及びキット
US6153378A (en) * 1992-10-16 2000-11-28 Bionova Corporation Diagnosis of, and vaccination against, a positive stranded RNA virus using an isolated, unprocessed polypeptide encoded by a substantially complete genome of such virus
JP2778886B2 (ja) * 1992-10-16 1998-07-23 エバーニュー バイオテック インコーポレイティド Ｃ型肝炎ウィルスのコア抗原タンパク質及びそれを用いての診断方法及びキット
AU6769594A (en) * 1993-04-22 1994-11-08 Genelabs Technologies, Inc. Hepatitis c virus immunodiagnostic antigens and antibodies
KR100330278B1 (ko) 1993-05-10 2002-08-19 카이론 코포레이션 간염c바이러스의타이핑방법및사용시약
EP1421951A3 (en) 1993-05-12 2005-10-05 Chiron Corporation Conserved motif of hepatitis C virus E2/NS1 region
US5610009A (en) * 1994-01-28 1997-03-11 Abbott Laboratories Mammalian expression systems for hepatitis C virus envelope genes
US5709995A (en) 1994-03-17 1998-01-20 The Scripps Research Institute Hepatitis C virus-derived peptides capable of inducing cytotoxic T lymphocyte responses
US6511812B1 (en) 1994-05-09 2003-01-28 Abbott Laboratories Method and test kit for use in improving immunoassay specificity
WO1995030902A1 (en) * 1994-05-09 1995-11-16 Abbott Laboratories Method and reagents useful for improving immunoassay specificity
EP0759979A4 (en) * 1994-05-10 1999-10-20 Gen Hospital Corp ANTISENSE OLIGONUCLEOTIDES INHIBITION OF HEPATITIS C VIRUS
JP3217600B2 (ja) 1994-07-12 2001-10-09 株式会社先端生命科学研究所 非ａ非ｂ型肝炎ウイルス関連抗原のイムノアッセイ、それに使用するモノクローナル抗体、およびこの抗体を産生するハイブリドーマ
DK0773957T3 (da) 1994-07-29 2005-10-24 Chiron Corp Udskilt hepatitis C-virus-E1/E2-kompleks opnået fra C-terminalt trunkerede E1- og E2-polypeptider
WO1996004301A2 (en) * 1994-07-29 1996-02-15 Chiron Corporation Novel hepatitis c e1 and e2 truncated polypeptides and methods of obtaining the same
PT721505E (pt) * 1994-07-29 2002-10-31 Innogenetics Nv Proteinas do envelope do virus da hepatite c purificadas para utilizacao em diagnostico e terapeutica
DE4428705A1 (de) * 1994-08-12 1996-02-15 Boehringer Mannheim Gmbh Rekombinantes Antigen aus der NS3-Region des Hepatitis C Virus
US6235888B1 (en) 1994-10-05 2001-05-22 The General Hospital Corporation Hepatitis C virus vaccine
EP0804584B2 (en) 1994-10-21 2008-07-09 Innogenetics N.V. Sequences of hepatitis c virus genotype 7 and their use as prophylactic, therapeutic and diagnostic agents
DE69617396T2 (de) * 1995-01-16 2002-09-05 Northern Sydney Area Health Service, St. Leonards T-Zellen beeinflussende Peptide
KR970010787A (ko) * 1995-08-14 1997-03-27 성재갑 B형 간염 바이러스 표면항원과 c형 간염 바이러스 외피 단백질의 융합 단백질 및 이를 포함하는 혼합 백신
US6127116A (en) 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
GB9517926D0 (en) 1995-09-01 1995-11-01 Biocine Spa Binding protein
US5837442A (en) 1995-11-29 1998-11-17 Roche Molecular Systems, Inc. Oligonucleotide primers for amplifying HCV nucleic acid
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
IT1284635B1 (it) * 1996-04-24 1998-05-21 Clonit Spa Metodo per la rivelazione di acidi nucleici amplificati e kit per il suo uso.
JP3715027B2 (ja) 1996-05-07 2005-11-09 シスメックス株式会社 Ｃ型肝炎ウイルス感染症診断薬
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
FR2760458B1 (fr) 1997-03-05 1999-04-23 Bio Merieux Peptide structural antigenique, composes antigenique et immunogene et utilisations dans la detection, la prevention et le traitement d'une infection par le vhc
WO1998050556A2 (en) 1997-05-06 1998-11-12 Chiron Corporation Intracellular production of hepatitis c e1 and e2 truncated polypeptides
DE69841322D1 (de) 1997-10-06 2010-01-07 Novartis Vaccines & Diagnostic Hepatitis c rezeptorprotein cd81
EP1154793B1 (en) 1999-02-26 2010-09-15 Novartis Vaccines and Diagnostics, Inc. Use of bioadhesives and adjuvants for the mucosal delivery of antigens
US8206749B1 (en) 1999-02-26 2012-06-26 Novartis Vaccines And Diagnostics, Inc. Microemulsions with adsorbed macromolecules and microparticles
US7196066B1 (en) 1999-11-03 2007-03-27 Powderject Vaccines, Inc. DNA-vaccines based on constructs derived from the genomes of human and animal pathogens
GB9927320D0 (en) * 1999-11-18 2000-01-12 Chiron Spa Exosome separation
JP4837229B2 (ja) 2000-06-15 2011-12-14 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 抗ｈｃｖ抗体についてのイムノアッセイ
EP1178116A1 (en) * 2000-08-03 2002-02-06 Hybrigenics S.A. Sid nucleic acids and polypeptides selected from a pathogenic strain of hepatitis C virus and applications thereof
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
AU9215101A (en) 2000-08-17 2002-02-25 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
JP4608210B2 (ja) 2001-05-31 2011-01-12 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド キメラアルファウイルスレプリコン粒子
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
US7049060B2 (en) * 2001-11-05 2006-05-23 Ortho-Clinical Diagnostics, Inc. HCV anti-core monoclonal antibodies
AU2003215316A1 (en) 2002-02-20 2003-09-09 Chiron Corporation Microparticles with adsorbed polypeptide-containing molecules
US7598421B2 (en) 2002-05-08 2009-10-06 Ucl Biomedica Plc Materials for the delivery of biologically-active material to cells
FR2839555B1 (fr) 2002-05-10 2007-07-27 Bio Rad Pasteur Procede de detection simultanee d'un antigene et d'un anticorps d'un microorganisme infectieux
FR2839722A1 (fr) 2002-05-17 2003-11-21 Bio Merieux Nouvelles compositions peptidiques et leur utilisation notamment dans la preparation de compositions pharmaceutiques actives contre le virus de l'hepatite c
ATE410693T1 (de) 2002-09-09 2008-10-15 Novartis Vaccines & Diagnostic Hcv-test
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
US7115374B2 (en) 2002-10-16 2006-10-03 Gen-Probe Incorporated Compositions and methods for detecting West Nile virus
EP2263687B1 (en) 2002-12-27 2015-03-25 Novartis Vaccines and Diagnostics, Inc. Immunogenic compositions containing phospholipid
US7695725B2 (en) 2003-02-06 2010-04-13 Aduro Biotech Modified free-living microbes, vaccine compositions and methods of use thereof
PT1592441E (pt) 2003-02-06 2012-05-21 Aduro Biotech Listeria atenuada relativamente à entrada em células não patogénicas, vacinas compreendendo a listeria e métodos para sua utilização
KR101173871B1 (ko) 2003-02-06 2012-08-16 앤저 테라퓨틱스 인코퍼레이티드 변형된 독립생존 미생물, 백신 조성물 및 그것의 사용방법
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
ES2596753T3 (es) 2003-08-29 2017-01-11 Fujirebio Europe N.V. Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo
WO2006070028A1 (es) * 2004-12-23 2006-07-06 Berthet Francois Xavier Composiciones y procedimientos para detectar infección patógena
US7842289B2 (en) 2003-12-24 2010-11-30 Aduro Biotech Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof
EP2612679A1 (en) 2004-07-29 2013-07-10 Novartis Vaccines and Diagnostics, Inc. Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
JP5070055B2 (ja) 2004-08-27 2012-11-07 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 改変タンパク分解性切断部位を有するｈｃｖ多エピトープ融合抗原およびその使用
PL1797112T3 (pl) * 2004-09-29 2011-04-29 The Administrators Of The Tulane Educational Fund Inhibitory wirusa zapalenia wątroby typu C
CA2618429A1 (en) 2005-05-25 2007-03-22 Tripep Ab A hepatitis c virus non-structural ns3/4a fusion gene
WO2008114622A1 (ja) 2007-03-20 2008-09-25 Terumo Kabushiki Kaisha 酸化発色化合物またはその塩およびその製造方法、ならびに試薬組成物およびこれを用いた試験具
US8071561B2 (en) 2007-08-16 2011-12-06 Chrontech Pharma Ab Immunogen platform
JP2011506334A (ja) 2007-12-07 2011-03-03 ノバルティス アーゲー 免疫応答を誘導するための組成物
WO2009130588A2 (en) 2008-04-22 2009-10-29 Tripep Ab Immunogen platform
KR20110027695A (ko) 2008-05-19 2011-03-16 아두로 바이오테크 Ｐｒｆａ＊ 돌연변이 리스테리아를 포함하는 조성물 및 그것의 사용방법
WO2010103017A2 (en) 2009-03-09 2010-09-16 William Henry Hapten-carrier conjugates with bacterial toxins having a signal peptide as carrier and their use in immunogenic compositions
EP2451475A2 (en) 2009-07-06 2012-05-16 Novartis AG Self replicating rna molecules and uses thereof
EP3449910A1 (en) 2010-07-06 2019-03-06 GlaxoSmithKline Biologicals S.A. Cationic oil-in-water emulsions
RU2606846C2 (ru) 2011-07-06 2017-01-10 Новартис Аг Эмульсии типа "масло в воде", которые содержат нуклеиновые кислоты
US9636410B2 (en) 2011-07-06 2017-05-02 Glaxosmithkline Biologicals Sa Cationic oil-in-water emulsions
AU2012322704B2 (en) 2011-10-11 2017-09-07 Novartis Ag Recombinant self-replicating polycistronic RNA molecules
EP2994754B1 (en) * 2013-05-10 2018-07-25 The United States of America, as represented by The Secretary, Department of Health and Human Services Compositions and methods for simultaneous detection of hcv antigen/antibody
RU2568872C1 (ru) * 2014-10-15 2015-11-20 Игорь Геннадьевич Сивов Лекарственное средство для лечения вирусного гепатита с
AU2014412513B2 (en) 2014-11-27 2021-04-08 Kimberly-Clark Worldwide, Inc. Devices and methods for detecting norovirus on surfaces
DK3274478T3 (da) 2015-03-27 2020-11-23 Ortho Clinical Diagnostics K K Hcv-ns4a/modificerede ns3-polypeptider og anvendelser deraf
US20200377606A1 (en) 2016-04-18 2020-12-03 Celldex Therapeutics, Inc. Agonistic antibodies that bind human cd40 and uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4542016A (en) * 1981-03-27 1985-09-17 Institut Merieux Non-a non-b hepatitis surface antigen useful for the preparation of vaccines and methods of use
US4702909A (en) * 1982-05-05 1987-10-27 Louisiana State University A & M Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent
US4870026A (en) * 1982-09-16 1989-09-26 The General Hospital Corporation Non-A, non-B. hepatitis, virus, methods of identification purification, characterization, diagnosis and immunization
US5032511A (en) * 1987-03-31 1991-07-16 Mitsubishi Kasei Corporation DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens
AU624105B2 (en) * 1987-11-18 1992-06-04 Novartis Vaccines And Diagnostics, Inc. Nanbv diagnostics and vaccines
HU220204B (hu) * 1987-11-18 2001-11-28 Chiron Corp. HCV polipeptidek és HCV polinukleotidok, ilyen polinukleotidokat tartalmazó vektorok és ezekkel transzformált gazdasejtek, valamint HCV fertőzés kimutatására szolgáló diagnosztikumok és immunvizsgálati készlet
WO1989012641A1 (en) * 1988-06-17 1989-12-28 Genelabs Incorporated Enterically transmitted non-a/non-b hepatitis viral agent
EP0423239A4 (en) * 1988-07-06 1992-05-20 Genelabs Incorporated Post-transfusion, non-a, non-b hepatitis virus and antigens
JP2696116B2 (ja) * 1988-09-30 1998-01-14 財団法人阪大微生物病研究会 非ａ非ｂ肝炎患者の血清と抗原抗体反応するペプチド、及び該ペプチドをコードするｄｎａ
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용

Also Published As

Publication number Publication date
DE388232T1 (de) 1991-05-02
AU4750693A (en) 1993-12-16
CA2012482C (en) 2004-11-23
JPH10295389A (ja) 1998-11-10
PT93480A (pt) 1990-11-07
IL93764A (en) 2003-12-10
JPH04504715A (ja) 1992-08-20
CA2012482A1 (en) 1990-09-17
JP2009275046A (ja) 2009-11-26
EP1034785A2 (en) 2000-09-13
JP2656995B2 (ja) 1997-09-24
AU5278390A (en) 1990-10-22
EP0388232B1 (en) 2005-01-12
KR0167125B1 (en) 1999-05-01
ATE286979T1 (de) 2005-01-15
HU211981A9 (en) 1996-01-29
IE20060608A1 (en) 2006-09-20
IE20060607A1 (en) 2006-09-20
EP0388232A1 (en) 1990-09-19
FI106211B (fi) 2000-12-15
KR920700045A (ko) 1992-02-19
JP2006111632A (ja) 2006-04-27
JPH10309197A (ja) 1998-11-24
EP1034785A3 (en) 2004-06-02
EP1394255A3 (en) 2004-06-02
AU666767B2 (en) 1996-02-22
DE69034182D1 (de) 2005-03-03
ES2020152A4 (es) 1991-08-01
WO1990011089A1 (en) 1990-10-04
JPH09215497A (ja) 1997-08-19
JP2007332148A (ja) 2007-12-27
EP0388232B9 (en) 2005-10-26
AU666766B2 (en) 1996-02-22
FI20002014A (fi) 2000-09-13
UA50829C2 (uk) 2002-11-15
DK0388232T3 (da) 2005-02-07
FI107610B (fi) 2001-09-14
ES2228297T1 (es) 2005-04-16
PT93480B (pt) 1997-07-31
JPH07145194A (ja) 1995-06-06
JP2693908B2 (ja) 1997-12-24
JP2009292819A (ja) 2009-12-17
EP1394255A2 (en) 2004-03-03
FI20002013A (fi) 2000-09-13
HUT54896A (en) 1991-04-29
HU225068B1 (en) 2006-05-29
FI905591A0 (fi) 1990-11-12
FI107619B (fi) 2001-09-14
JPH07101986A (ja) 1995-04-18
JP2809987B2 (ja) 1998-10-15
JP3171792B2 (ja) 2001-06-04
DE03016585T1 (de) 2005-03-31
ES2020152T3 (es) 2005-07-16
MY110260A (en) 1998-03-31
NO303941B1 (no) 1998-09-28
JP2007254475A (ja) 2007-10-04
AU4750493A (en) 1994-01-20
AU640920B2 (en) 1993-09-09
AU4750593A (en) 1993-12-16
KR0185373B1 (ko) 1999-05-01
ES2020152T4 (es) 2006-11-16
IL93764A0 (en) 1990-12-23
AU666576B2 (en) 1996-02-15
GR910300016T1 (en) 1991-11-15
NO904712L (no) 1990-10-30
HU902814D0 (en) 1991-03-28
JP2000039434A (ja) 2000-02-08
JP2006169233A (ja) 2006-06-29
DE69034182T2 (de) 2005-12-15

Similar Documents

Publication Publication Date Title
NO904712D0 (no) Nanbh diagnostiske midler og vaksiner.
YU48038B (sh) Postupak za dijagnostiku ne-a, ne-v hepatitisa
Collett et al. Bovine viral diarrhea virus genomic organization
DE69334357D1 (de) Nachweis und Typisierung das Hepatitis C Virus (HCV) mittels 5'UTR und NS5 Nukleinsäuresequenzen
WO1994025601A3 (en) New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
WO1996013590A3 (en) New sequences of hepatitis c virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
ES2029171A6 (es) Un procedimiento para preparar un polipeptido virico de hepatitis no a y no b post-transfusional (pt-nanbh)
DK0585398T3 (da) HCV genomiske sekvenser til diagnostiske og terapeutiske midler
DE69434116D1 (en) Hepatitis-c virus typ 4,5 und 6
KR870000426A (ko) 합성 fmdv 백신용 화합물의 제조방법
Shukla et al. Evaluation of complete genome sequences and sequences of individual gene products for the classification of hepatitis C viruses
Katayama et al. Full-length GBV-C/HGV genomes from nine Japanese isolates: characterization by comparative analyses
DE69433160D1 (de) Konserviertes Motiv der Hepatitis C Virus E2/NS1 Region
Akkina Pestivirus bovine viral diarrhea virus polypeptides: identification of new precursor proteins and alternative cleavage pathways
KR900009979A (ko) 일본 뇌염 비루스 비구조 단백질의 제조방법
Wong et al. Molecular cloning and nucleotide sequence of 3′-terminal region of classical swine fever virus LPC vaccine strain
Kim et al. Genotype distribution and comparison of the putative envelope region of hepatitis C virus from Korean patients
IS3511A7 (is) Fjölpeptíð framleidd með aðferðum líftækninnar, kjarnsýrur sem samsvara þeim, og notkun fjölpeptíðanna sem bóluefnis gegn VHS veiru í fiski

Legal Events

Date Code Title Description
MK1K Patent expired