NO317296B1 - Hypnotisk <beta>- karbolinderivater, fremgangsmater til deres fremstilling og deres anvendelse som legemiddelprodukt - Google Patents

Hypnotisk <beta>- karbolinderivater, fremgangsmater til deres fremstilling og deres anvendelse som legemiddelprodukt Download PDF

Info

Publication number: NO317296B1
Authority: NO; Norway
Prior art keywords: methoxy; quinolizin; general formula; derivatives; ethyl
Prior art date: 1998-03-17

Application number

NO20004638A

Other languages

English (en)

Norwegian (no)

Other versions

NO20004638L (no

NO20004638D0 (no

Inventor

Jean-Claude Jacquesy

Marie-Paule Jouannetaud

Bruno Violeau

Omar Karam

Jean-Bernard Fourtillan

Marianne Fourtillan

Original Assignee

Besins Iscovesco Lab

Macef

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-17

Filing date

2000-09-15

Publication date

2004-10-04

1998-03-17 Priority claimed from US09/042,990 external-priority patent/US6048868A/en

2000-09-15 Application filed by Besins Iscovesco Lab, Macef filed Critical Besins Iscovesco Lab

2000-09-15 Publication of NO20004638D0 publication Critical patent/NO20004638D0/no

2000-11-16 Publication of NO20004638L publication Critical patent/NO20004638L/no

2004-10-04 Publication of NO317296B1 publication Critical patent/NO317296B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Anesthesiology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)

NO20004638A 1998-03-17 2000-09-15 Hypnotisk <beta>- karbolinderivater, fremgangsmater til deres fremstilling og deres anvendelse som legemiddelprodukt NO317296B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/042,990 US6048868A (en)	1994-09-14	1998-03-17	Melatonin-antagonist β-carboline derivatives and analogues thereof containing naphthalenic structure, process for their preparation and their use as medicinal products
PCT/IB1999/000494 WO1999047521A1 (en)	1998-03-17	1999-03-17	HYPNOTIC β-CARBOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS

Publications (3)

Publication Number	Publication Date
NO20004638D0 NO20004638D0 (no)	2000-09-15
NO20004638L NO20004638L (no)	2000-11-16
NO317296B1 true NO317296B1 (no)	2004-10-04

Family

ID=21924862

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20004638A NO317296B1 (no)	1998-03-17	2000-09-15	Hypnotisk <beta>- karbolinderivater, fremgangsmater til deres fremstilling og deres anvendelse som legemiddelprodukt

Country Status (24)

Country	Link
EP (1)	EP1064284B1 (sk)
JP (1)	JP4333036B2 (sk)
CN (1)	CN1115342C (sk)
AR (1)	AR018767A1 (sk)
AT (1)	ATE215087T1 (sk)
AU (1)	AU752364B2 (sk)
BG (1)	BG63973B1 (sk)
BR (1)	BR9908833A (sk)
CA (1)	CA2324270A1 (sk)
DE (1)	DE69901098T2 (sk)
DK (1)	DK1064284T3 (sk)
ES (1)	ES2174632T3 (sk)
HU (1)	HUP0101234A3 (sk)
IL (1)	IL138442A (sk)
IS (1)	IS2199B (sk)
NO (1)	NO317296B1 (sk)
NZ (1)	NZ506913A (sk)
PL (1)	PL193450B1 (sk)
PT (1)	PT1064284E (sk)
RU (1)	RU2210571C2 (sk)
SK (1)	SK284387B6 (sk)
TR (1)	TR200003596T2 (sk)
UA (1)	UA71911C2 (sk)
WO (1)	WO1999047521A1 (sk)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2824829B1 (fr) *	2001-05-16	2005-06-03	Macef	Nouveaux derives de dihydroimidazo [5,1-a]-beta-carboline, leur procede de preparation et leur application a titre de medicament
FR2904973A1 (fr) *	2006-08-18	2008-02-22	Fourtillan Snc	Derives de 1-methylidene-pyrido[3,4-b]indole et leur utilisation en therapeutique.
FR2916200A1 (fr) *	2007-05-18	2008-11-21	Fourtillan Snc	Nouveaux derives des 1,2,3,4,6,7,12,12a-octahydro pyrazino[1',2':1,6]pyrido[3,4-b]indoles, leur preparation et leur utilisation en therapeutique
NZ586120A (en)	2008-01-11	2012-07-27	Albany Molecular Res Inc	(1-azinone) -substituted pyridoindoles as mch antagonists
WO2011003012A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
WO2011003021A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en)	2009-07-01	2011-01-06	Albany Molecular Research, Inc.	Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
EP2448585B1 (en)	2009-07-01	2014-01-01	Albany Molecular Research, Inc.	Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en)	2010-12-21	2012-06-28	Albany Molecular Research, Inc.	Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
US8697700B2 (en)	2010-12-21	2014-04-15	Albany Molecular Research, Inc.	Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
FI130627B (en) *	2021-03-31	2023-12-18	Equinorm Ltd	Novel heterocyclic compounds and their use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5283343A (en) *	1987-08-17	1994-02-01	Whitby Research, Inc.	2-aryl substituted N-acetyltryptamines and process of preparing such
FR2724384B1 (fr) *	1994-09-14	1999-04-16	Cemaf	Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament

1999
- 1999-03-17 NZ NZ506913A patent/NZ506913A/en unknown
- 1999-03-17 JP JP2000536716A patent/JP4333036B2/ja not_active Expired - Fee Related
- 1999-03-17 ES ES99939844T patent/ES2174632T3/es not_active Expired - Lifetime
- 1999-03-17 SK SK1385-2000A patent/SK284387B6/sk not_active IP Right Cessation
- 1999-03-17 IL IL138442A patent/IL138442A/en not_active IP Right Cessation
- 1999-03-17 HU HU0101234A patent/HUP0101234A3/hu unknown
- 1999-03-17 PT PT99939844T patent/PT1064284E/pt unknown
- 1999-03-17 TR TR2000/03596T patent/TR200003596T2/xx unknown
- 1999-03-17 DE DE69901098T patent/DE69901098T2/de not_active Expired - Lifetime
- 1999-03-17 RU RU2000126288/04A patent/RU2210571C2/ru not_active IP Right Cessation
- 1999-03-17 PL PL99342929A patent/PL193450B1/pl not_active IP Right Cessation
- 1999-03-17 UA UA2000105839A patent/UA71911C2/uk unknown
- 1999-03-17 BR BR9908833-9A patent/BR9908833A/pt not_active Application Discontinuation
- 1999-03-17 DK DK99939844T patent/DK1064284T3/da active
- 1999-03-17 AT AT99939844T patent/ATE215087T1/de not_active IP Right Cessation
- 1999-03-17 CN CN99805687A patent/CN1115342C/zh not_active Expired - Fee Related
- 1999-03-17 AU AU32707/99A patent/AU752364B2/en not_active Ceased
- 1999-03-17 EP EP99939844A patent/EP1064284B1/en not_active Expired - Lifetime
- 1999-03-17 WO PCT/IB1999/000494 patent/WO1999047521A1/en active IP Right Grant
- 1999-03-17 AR ARP990101166A patent/AR018767A1/es active IP Right Grant
- 1999-03-17 CA CA002324270A patent/CA2324270A1/en not_active Abandoned
2000
- 2000-09-12 IS IS5627A patent/IS2199B/is unknown
- 2000-09-14 BG BG104768A patent/BG63973B1/bg unknown
- 2000-09-15 NO NO20004638A patent/NO317296B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0101234A3 (en)	2002-12-28
JP4333036B2 (ja)	2009-09-16
EP1064284A1 (en)	2001-01-03
DE69901098D1 (de)	2002-05-02
DK1064284T3 (da)	2002-07-22
IL138442A (en)	2006-12-10
AU3270799A (en)	1999-10-11
PL342929A1 (en)	2001-07-16
DE69901098T2 (de)	2002-11-21
CN1299361A (zh)	2001-06-13
ATE215087T1 (de)	2002-04-15
AU752364B2 (en)	2002-09-19
NZ506913A (en)	2003-07-25
NO20004638L (no)	2000-11-16
EP1064284B1 (en)	2002-03-27
TR200003596T2 (tr)	2001-04-20
JP2002506867A (ja)	2002-03-05
UA71911C2 (en)	2005-01-17
BR9908833A (pt)	2000-11-21
BG63973B1 (bg)	2003-08-29
PT1064284E (pt)	2002-09-30
ES2174632T3 (es)	2002-11-01
CN1115342C (zh)	2003-07-23
IS2199B (is)	2007-02-15
PL193450B1 (pl)	2007-02-28
AR018767A1 (es)	2001-12-12
HUP0101234A2 (hu)	2001-12-28
IL138442A0 (en)	2001-10-31
RU2210571C2 (ru)	2003-08-20
SK284387B6 (sk)	2005-02-04
BG104768A (en)	2001-05-31
CA2324270A1 (en)	1999-09-23
NO20004638D0 (no)	2000-09-15
WO1999047521A1 (en)	1999-09-23
IS5627A (is)	2000-09-12
SK13852000A3 (sk)	2001-09-11

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Legal Events

Date	Code	Title	Description
2011-10-24	MM1K	Lapsed by not paying the annual fees