NO313813B1 - Transdermale, terapeutiske systemer som inneholder seksualsteroider og anvendelser - Google Patents

Transdermale, terapeutiske systemer som inneholder seksualsteroider og anvendelser Download PDF

Info

Publication number: NO313813B1
Authority: NO; Norway
Prior art keywords: transdermal; dimethylisosorbide; adhesive; contain; active substances
Prior art date: 1994-02-18

Application number

NO19963447A

Other languages

English (en)

Norwegian (no)

Other versions

NO963447L (no

Inventor

Ralph Lipp

Clemens Gunther

Jutta Riedl

Ulrich Touber

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-02-18

Filing date

1996-08-19

Publication date

2002-12-09

1996-08-19 Application filed by Schering Ag filed Critical Schering Ag

1996-08-19 Publication of NO963447L publication Critical patent/NO963447L/no

2002-12-09 Publication of NO313813B1 publication Critical patent/NO313813B1/no

Links

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125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
230000037317 transdermal delivery Effects 0.000 description 1
CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 1
229940029284 trichlorofluoromethane Drugs 0.000 description 1
150000004670 unsaturated fatty acids Chemical class 0.000 description 1
235000021122 unsaturated fatty acids Nutrition 0.000 description 1
229920002554 vinyl polymer Polymers 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)

NO19963447A 1994-02-18 1996-08-19 Transdermale, terapeutiske systemer som inneholder seksualsteroider og anvendelser NO313813B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4405898A DE4405898A1 (de)	1994-02-18	1994-02-18	Transdermale therapeutische Systeme enthaltend Sexualsteroide
PCT/EP1995/000483 WO1995022322A1 (fr)	1994-02-18	1995-02-09	Systemes therapeutiques transdermiques contenant des steroides sexuels

Publications (2)

Publication Number	Publication Date
NO963447L NO963447L (no)	1996-08-19
NO313813B1 true NO313813B1 (no)	2002-12-09

Family

ID=6511044

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19963447A NO313813B1 (no)	1994-02-18	1996-08-19	Transdermale, terapeutiske systemer som inneholder seksualsteroider og anvendelser

Country Status (17)

Country	Link
US (1)	US5904931A (fr)
EP (1)	EP0744944B1 (fr)
JP (1)	JPH09508912A (fr)
KR (1)	KR100392435B1 (fr)
AT (1)	ATE186213T1 (fr)
AU (1)	AU1706695A (fr)
CA (1)	CA2183543C (fr)
DE (2)	DE4405898A1 (fr)
DK (1)	DK0744944T3 (fr)
ES (1)	ES2140658T3 (fr)
GR (1)	GR3032512T3 (fr)
HU (1)	HUT74876A (fr)
NO (1)	NO313813B1 (fr)
NZ (1)	NZ279820A (fr)
PT (1)	PT744944E (fr)
RU (1)	RU2154455C2 (fr)
WO (1)	WO1995022322A1 (fr)

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1994
- 1994-02-18 DE DE4405898A patent/DE4405898A1/de not_active Withdrawn
1995
- 1995-02-09 KR KR1019960704501A patent/KR100392435B1/ko not_active IP Right Cessation
- 1995-02-09 DE DE59507188T patent/DE59507188D1/de not_active Expired - Fee Related
- 1995-02-09 JP JP7521561A patent/JPH09508912A/ja active Pending
- 1995-02-09 US US08/693,050 patent/US5904931A/en not_active Expired - Fee Related
- 1995-02-09 AU AU17066/95A patent/AU1706695A/en not_active Abandoned
- 1995-02-09 DK DK95908925T patent/DK0744944T3/da active
- 1995-02-09 ES ES95908925T patent/ES2140658T3/es not_active Expired - Lifetime
- 1995-02-09 EP EP95908925A patent/EP0744944B1/fr not_active Expired - Lifetime
- 1995-02-09 PT PT95908925T patent/PT744944E/pt unknown
- 1995-02-09 AT AT95908925T patent/ATE186213T1/de not_active IP Right Cessation
- 1995-02-09 HU HU9602283A patent/HUT74876A/hu unknown
- 1995-02-09 RU RU96118462/14A patent/RU2154455C2/ru not_active IP Right Cessation
- 1995-02-09 NZ NZ279820A patent/NZ279820A/en not_active IP Right Cessation
- 1995-02-09 WO PCT/EP1995/000483 patent/WO1995022322A1/fr active IP Right Grant
- 1995-02-09 CA CA002183543A patent/CA2183543C/fr not_active Expired - Fee Related
1996
- 1996-08-19 NO NO19963447A patent/NO313813B1/no not_active IP Right Cessation
2000
- 2000-01-28 GR GR20000400206T patent/GR3032512T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR100392435B1 (ko)	2003-11-28
WO1995022322A1 (fr)	1995-08-24
HU9602283D0 (en)	1996-10-28
EP0744944A1 (fr)	1996-12-04
DE4405898A1 (de)	1995-08-24
KR970701039A (ko)	1997-03-17
ES2140658T3 (es)	2000-03-01
JPH09508912A (ja)	1997-09-09
AU1706695A (en)	1995-09-04
GR3032512T3 (en)	2000-05-31
DE59507188D1 (de)	1999-12-09
CA2183543A1 (fr)	1995-08-24
NZ279820A (en)	1998-08-26
EP0744944B1 (fr)	1999-11-03
DK0744944T3 (da)	2000-04-25
HUT74876A (en)	1997-02-28
US5904931A (en)	1999-05-18
PT744944E (pt)	2000-04-28
RU2154455C2 (ru)	2000-08-20
CA2183543C (fr)	2009-07-14
NO963447L (no)	1996-08-19
ATE186213T1 (de)	1999-11-15

Publication	Publication Date	Title
NO313813B1 (no)	2002-12-09	Transdermale, terapeutiske systemer som inneholder seksualsteroider og anvendelser
AU710760B2 (en)	1999-09-30	Drug delivery compositions for improved stability of steroids
DK171138B1 (da)	1996-07-01	Transdermal absorptionsdosisenhed til behandling af postmenopausesyndrom
RU2176499C2 (ru)	2001-12-10	Композиция для чрескожного введения стероидных лекарственных средств и содержащий ее препарат
NO180567B (no)	1997-02-03	Befruktningshindrende og/eller syklusregulerende middel for transdermal applikasjon
JPH09501398A (ja)	1997-02-10	活性成分パッチ
US20010023261A1 (en)	2001-09-20	Novel composition for the transdermal administration of drugs
NO335025B1 (no)	2014-08-25	Forsterket medikamentlevering i transdermale systemer
WO2011000210A1 (fr)	2011-01-06	Composition d'un promoteur de permeation et utilisation associee dans un systeme d'administration de medicament transdermique
JP4965263B2 (ja)	2012-07-04	浸透増強剤を必要としないホルモンの経皮送達
NZ279226A (en)	1998-05-27	Desogestrel-containing transdermal application
RU2044541C1 (ru)	1995-09-27	Способ получения лечебного средства для трансдермального применения
AU724308B2 (en)	2000-09-14	Transdermal therapeutic systems that contain sex steroids
JPH11509222A (ja)	1999-08-17	１３−エチル−１７β−ヒドロキシ−１１−メチレン−１８，１９−ジノル−１７α−プレグン−４−エン−２０−イン−３−オンのエステルを含む経皮投与のための剤
MXPA99006959A (en)	2000-01-01	Composition for the transdermal administration of steroid drugs

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