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NO2015005I2 - Flutemetamol (18F) - Google Patents

Flutemetamol (18F)

Info

Publication number
NO2015005I2
NO2015005I2 NO2015005C NO2015005C NO2015005I2 NO 2015005 I2 NO2015005 I2 NO 2015005I2 NO 2015005 C NO2015005 C NO 2015005C NO 2015005 C NO2015005 C NO 2015005C NO 2015005 I2 NO2015005 I2 NO 2015005I2
Authority
NO
Norway
Prior art keywords
fluoromethamol
Prior art date
Application number
NO2015005C
Other languages
English (en)
Other versions
NO2015005I1 (no
Original Assignee
Univ Pittsburgh Commonwealth Sys Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en
Application filed by Univ Pittsburgh Commonwealth Sys Higher Education filed Critical Univ Pittsburgh Commonwealth Sys Higher Education
Publication of NO2015005I2 publication Critical patent/NO2015005I2/no
Publication of NO2015005I1 publication Critical patent/NO2015005I1/no

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/64Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO2015005C 2003-03-14 2015-02-18 Flutemetamol (18F) NO2015005I1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en) 2003-03-14 2004-03-15 Benzothiazole derivative compounds, compositions and uses

Publications (2)

Publication Number Publication Date
NO2015005I2 true NO2015005I2 (no) 2015-02-18
NO2015005I1 NO2015005I1 (no) 2015-03-02

Family

ID=35057877

Family Applications (3)

Application Number Title Priority Date Filing Date
NO20054674A NO330861B1 (no) 2003-03-14 2005-10-11 Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no) 2003-03-14 2011-07-06 Benzotiazolavledede forbindelser, preparater og anvendelser
NO2015005C NO2015005I1 (no) 2003-03-14 2015-02-18 Flutemetamol (18F)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO20054674A NO330861B1 (no) 2003-03-14 2005-10-11 Benzotiazolavledede forbindelser, preparater og anvendelser
NO20110980A NO20110980L (no) 2003-03-14 2011-07-06 Benzotiazolavledede forbindelser, preparater og anvendelser

Country Status (16)

Country Link
EP (1) EP1611115B1 (no)
JP (1) JP4875487B2 (no)
CN (2) CN1784392A (no)
AU (2) AU2004221897B2 (no)
BE (1) BE2015C005I2 (no)
BR (1) BRPI0408274B8 (no)
CY (2) CY1113334T1 (no)
DK (1) DK1611115T3 (no)
ES (1) ES2393921T3 (no)
FR (1) FR15C0005I2 (no)
HU (1) HUS1500006I1 (no)
NO (3) NO330861B1 (no)
PL (1) PL1611115T3 (no)
PT (1) PT1611115E (no)
RU (1) RU2440995C2 (no)
SI (1) SI1611115T1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
HU230375B1 (hu) 2000-08-24 2016-03-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Tioflavin-származékok és alkalmazásuk az Alzheimer-kór diagnózisában és kezelésében
BRPI0510033A (pt) * 2004-05-20 2007-10-02 Scripps Res Insittute estabilização de transtiretina
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
RU2494669C2 (ru) * 2007-01-30 2013-10-10 Джи-И Хелткер Лимитед Средства диагностики нейродегенеративных заболеваний
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
JP2011529086A (ja) * 2008-07-24 2011-12-01 シーメンス メディカル ソリューションズ ユーエスエー インコーポレイテッド Ad病変を同定するために有用な造影剤
US8895313B2 (en) * 2008-09-23 2014-11-25 Wista Laboratories Ltd. Ligands for aggregated tau molecules
EP3049411B1 (en) * 2013-09-26 2017-04-26 F. Hoffmann-La Roche AG Imidazo[1,2-a]pyridin-7-amines as imaging tools
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
ES2818107T3 (es) * 2014-08-29 2021-04-09 Chdi Foundation Inc Sondas para obtener imágenes de la proteína huntingtina
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998022493A2 (en) * 1996-11-22 1998-05-28 Elan Pharmaceuticals, Inc. N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
HU230375B1 (hu) * 2000-08-24 2016-03-29 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Tioflavin-származékok és alkalmazásuk az Alzheimer-kór diagnózisában és kezelésében
WO2002051821A1 (en) * 2000-12-22 2002-07-04 Astrazeneca Ab Therapeutic compounds
JP4317955B2 (ja) * 2001-04-23 2009-08-19 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア アミロイド斑凝集阻害剤および診断用造影剤
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
EP1611115B1 (en) 2012-08-22
SI1611115T1 (sl) 2012-12-31
AU2011200667A1 (en) 2011-03-10
BRPI0408274B1 (pt) 2019-02-26
PT1611115E (pt) 2012-12-07
CY1113334T1 (el) 2015-12-09
AU2011200667B2 (en) 2011-12-22
CN1784392A (zh) 2006-06-07
RU2440995C2 (ru) 2012-01-27
ES2393921T3 (es) 2013-01-02
NO20054674D0 (no) 2005-10-11
PL1611115T3 (pl) 2013-01-31
JP4875487B2 (ja) 2012-02-15
BE2015C005I2 (no) 2023-03-07
FR15C0005I2 (fr) 2015-07-24
NO2015005I1 (no) 2015-03-02
BRPI0408274A (pt) 2006-03-21
JP2006522104A (ja) 2006-09-28
CN102532055B (zh) 2016-05-11
AU2004221897A1 (en) 2004-09-30
EP1611115A1 (en) 2006-01-04
NO20054674L (no) 2005-12-13
BRPI0408274B8 (pt) 2021-05-25
RU2005131872A (ru) 2006-02-27
AU2004221897B2 (en) 2010-11-18
AU2004221897A2 (en) 2004-09-30
CN102532055A (zh) 2012-07-04
NO330861B1 (no) 2011-08-01
NO20110980L (no) 2005-12-13
DK1611115T3 (da) 2012-11-26
CY2015007I1 (el) 2015-12-09
HUS1500006I1 (hu) 2015-02-18
AU2004221897A9 (en) 2009-08-20
HK1086270A1 (en) 2006-09-15

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