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NO20055688L - Organiske forbindelser - Google Patents

Organiske forbindelser

Info

Publication number
NO20055688L
NO20055688L NO20055688A NO20055688A NO20055688L NO 20055688 L NO20055688 L NO 20055688L NO 20055688 A NO20055688 A NO 20055688A NO 20055688 A NO20055688 A NO 20055688A NO 20055688 L NO20055688 L NO 20055688L
Authority
NO
Norway
Prior art keywords
compounds
organic compounds
muscarinic
meanings
receptor
Prior art date
Application number
NO20055688A
Other languages
English (en)
Other versions
NO20055688D0 (no
Inventor
Gurdip Bhalay
Stephen Paul Collingwood
Brian Cox
Urs Baettig
Nicholas James Devereux
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20055688(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0324887A external-priority patent/GB0324887D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20055688D0 publication Critical patent/NO20055688D0/no
Publication of NO20055688L publication Critical patent/NO20055688L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Forbindelser med formel I i salt eller zwitterionform hvori, R1, R2, R3, og R4 har betydningene som indikert i beskrivelsen, som er anvendelige for behandling av tilstander som medieres av muskarin M3 reseptor. Farmasøytiske sammensetninger som inneholder forbindelsene og en fremgangsmåte for fremstilling av forbindelsene er også beskrevet.
NO20055688A 2003-05-02 2005-12-01 Organiske forbindelser NO20055688L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0310232 2003-05-02
GB0324887A GB0324887D0 (en) 2003-10-24 2003-10-24 Organic compounds
PCT/EP2004/004605 WO2004096800A2 (en) 2003-05-02 2004-04-30 Quinuclidine derivatives binding to mucarinic m3 receptors

Publications (2)

Publication Number Publication Date
NO20055688D0 NO20055688D0 (no) 2005-12-01
NO20055688L true NO20055688L (no) 2006-01-09

Family

ID=33420896

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055688A NO20055688L (no) 2003-05-02 2005-12-01 Organiske forbindelser

Country Status (32)

Country Link
US (2) US20070060563A1 (no)
EP (1) EP1631569B1 (no)
JP (1) JP4416786B2 (no)
KR (1) KR100896544B1 (no)
AR (1) AR044134A1 (no)
AT (1) ATE440840T1 (no)
AU (1) AU2004234069B2 (no)
BR (1) BRPI0410238A (no)
CA (1) CA2523436C (no)
CL (1) CL2004000918A1 (no)
CO (1) CO5700782A2 (no)
CY (1) CY1109655T1 (no)
DE (1) DE602004022805D1 (no)
DK (1) DK1631569T3 (no)
EC (1) ECSP056134A (no)
ES (1) ES2331185T3 (no)
HK (1) HK1087704A1 (no)
HR (1) HRP20050933A2 (no)
IL (1) IL171591A (no)
IS (1) IS2746B (no)
MA (1) MA27775A1 (no)
MX (1) MXPA05011739A (no)
MY (1) MY142652A (no)
NO (1) NO20055688L (no)
NZ (1) NZ542995A (no)
PE (1) PE20050465A1 (no)
PL (1) PL1631569T3 (no)
PT (1) PT1631569E (no)
RU (1) RU2363700C2 (no)
SI (1) SI1631569T1 (no)
TW (1) TWI340139B (no)
WO (1) WO2004096800A2 (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0428416D0 (en) 2004-12-24 2005-02-02 Novartis Ag Organic compounds
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1894568A1 (en) * 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
MX2009006018A (es) * 2006-12-19 2009-06-16 Astrazeneca Ab Derivados de quinuclidinol como antagonistas de receptores muscarinicos.
EP1950196A1 (de) * 2007-01-29 2008-07-30 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
ES2375516T3 (es) 2007-09-07 2012-03-01 Theravance, Inc. Compuestos que contienen guanidina, útiles como antagonistas del receptor muscar�?nico.
WO2009079392A1 (en) * 2007-12-14 2009-06-25 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
JP5584138B2 (ja) 2008-01-11 2014-09-03 ノバルティス アーゲー キナーゼ阻害剤としてのピリミジン類
GB0808709D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New combination 295
CN102089304A (zh) 2008-05-13 2011-06-08 阿斯利康(瑞典)有限公司 作为m3毒蕈碱性受体拮抗剂的奎宁环衍生物
CN102088976B (zh) * 2008-05-13 2012-12-26 阿斯利康(瑞典)有限公司 包含毒蕈碱性受体拮抗剂和β2-肾上腺素受体激动剂的药物产品
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
EP2585459B1 (en) * 2010-06-22 2015-01-07 Chiesi Farmaceutici S.p.A. Alkaloid aminoester derivatives and medicinal compositions thereof
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
ES2551592T3 (es) 2011-02-25 2015-11-20 Novartis Ag Pirazolo[1,5-a]piridinas como inhibidores de TRK
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
BR112014013179A2 (pt) * 2011-12-30 2017-06-13 Chiesi Farm Spa compostos, combinação de um composto, composição farmacêutica e usos de um composto
US9687488B2 (en) 2012-05-03 2017-06-27 St. Louis College Of Pharmacy Compositions and methods for increasing neurotrophic peptides
TWI647227B (zh) * 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs) 2013-10-29 2017-07-12 Zentiva, K.S. Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) * 2015-03-30 2018-10-25 Hovione Farm S A Processo de preparação de brometo de aclidínio
EP3111978B1 (en) 2015-07-03 2021-09-01 Novartis AG Inhaler adapted to read information stored in a data storage means of a container

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
DK534178A (da) * 1977-12-16 1979-06-17 Interx Research Corp Anticholinerge midler med sektrtionshaemmende virkning
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
CA2415468A1 (en) * 2000-07-11 2003-01-10 Yoshio Ogino Ester derivatives
AU2002238471B2 (en) * 2000-12-28 2007-06-28 Almirall, S.A. Quinuclidine derivatives and their use as M3 antagonists
GEP20063958B (en) * 2001-12-20 2006-11-10 Chiesi Farma Spa 1-alkyl-1-azoniabicyclo [2.2.2] octane carbamate derivatives and their use as muscarinic receptor antagonists
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

Also Published As

Publication number Publication date
PL1631569T3 (pl) 2010-02-26
IS8158A (is) 2005-11-30
NZ542995A (en) 2009-02-28
BRPI0410238A (pt) 2006-05-16
DK1631569T3 (da) 2009-11-23
EP1631569A2 (en) 2006-03-08
IL171591A (en) 2010-11-30
US8168654B2 (en) 2012-05-01
DE602004022805D1 (de) 2009-10-08
ATE440840T1 (de) 2009-09-15
RU2005137360A (ru) 2006-07-27
JP4416786B2 (ja) 2010-02-17
EP1631569B1 (en) 2009-08-26
KR100896544B1 (ko) 2009-05-07
CL2004000918A1 (es) 2005-02-11
PT1631569E (pt) 2009-11-26
SI1631569T1 (sl) 2010-01-29
TWI340139B (en) 2011-04-11
MA27775A1 (fr) 2006-02-01
AR044134A1 (es) 2005-08-24
MXPA05011739A (es) 2006-01-26
RU2363700C2 (ru) 2009-08-10
CO5700782A2 (es) 2006-11-30
TW200505920A (en) 2005-02-16
US20100041887A1 (en) 2010-02-18
JP2006525267A (ja) 2006-11-09
MY142652A (en) 2010-12-15
PE20050465A1 (es) 2005-07-18
HRP20050933A2 (en) 2006-12-31
WO2004096800A2 (en) 2004-11-11
KR20060015572A (ko) 2006-02-17
AU2004234069B2 (en) 2008-02-21
IS2746B (is) 2011-08-15
CA2523436A1 (en) 2004-11-11
HK1087704A1 (en) 2006-10-20
ES2331185T3 (es) 2009-12-23
US20070060563A1 (en) 2007-03-15
NO20055688D0 (no) 2005-12-01
AU2004234069A1 (en) 2004-11-11
ECSP056134A (es) 2006-04-19
CY1109655T1 (el) 2014-08-13
WO2004096800A3 (en) 2005-01-06
CA2523436C (en) 2011-11-01

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application