NO20052883L - New drugs for the treatment of chronic obstructive airway disease. - Google Patents
New drugs for the treatment of chronic obstructive airway disease.Info
- Publication number
- NO20052883L NO20052883L NO20052883A NO20052883A NO20052883L NO 20052883 L NO20052883 L NO 20052883L NO 20052883 A NO20052883 A NO 20052883A NO 20052883 A NO20052883 A NO 20052883A NO 20052883 L NO20052883 L NO 20052883L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- chronic obstructive
- new drugs
- airway disease
- obstructive airway
- Prior art date
Links
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 title abstract 3
- 239000002547 new drug Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Anvendelsen av forbindelser med den generelle formel (I) hvor restene R\ R^ og R^ kan ha de betydninger som er nevnt i patentkravene og i beskrivelsen, til fremstilling av et legemiddel til behandling av COPD (kronisk obstruktiv lungesykdom), samt nye forbindelser med den generelle formel (i) som sådanne, beskrives.The use of compounds of general formula (I) wherein the residues R 1, R 2 and R 2 may have the meanings mentioned in the claims and in the specification for the manufacture of a medicament for the treatment of COPD (chronic obstructive pulmonary disease), as well as new compounds. with general formula (i) as such is described.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10253282A DE10253282A1 (en) | 2002-11-15 | 2002-11-15 | Treatment of chronic obstructive pulmonary disease, using new or known N-substituted 2-amino-1-(benz-(1,4)-oxazin-3-on-8-yl)-ethanol derivative beta-mimetic agents, suitable for once-daily administration |
| PCT/EP2003/012565 WO2004045618A2 (en) | 2002-11-15 | 2003-11-11 | Novel medicaments for the treatment of chronic obstructive pulmonary diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20052883L true NO20052883L (en) | 2005-06-14 |
| NO334314B1 NO334314B1 (en) | 2014-02-03 |
Family
ID=32185709
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052883A NO334314B1 (en) | 2002-11-15 | 2005-06-14 | Compounds, pharmaceutical formulations containing such and their use in the manufacture of medicaments for the treatment of chronic obstructive pulmonary disease |
| NO2014005C NO2014005I1 (en) | 2002-11-15 | 2014-03-10 | olodaterol, acid addition salts and pharmacologically acceptable acids thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2014005C NO2014005I1 (en) | 2002-11-15 | 2014-03-10 | olodaterol, acid addition salts and pharmacologically acceptable acids thereof |
Country Status (38)
| Country | Link |
|---|---|
| EP (2) | EP1562603B3 (en) |
| JP (1) | JP4317138B2 (en) |
| KR (1) | KR101092247B1 (en) |
| CN (3) | CN101817800A (en) |
| AR (2) | AR041969A1 (en) |
| AT (1) | ATE430569T1 (en) |
| AU (1) | AU2003285326B2 (en) |
| BE (1) | BE2014C016I2 (en) |
| BR (1) | BRPI0316264B8 (en) |
| CA (1) | CA2506082C (en) |
| CO (1) | CO5570670A2 (en) |
| CY (2) | CY1110500T1 (en) |
| DE (2) | DE10253282A1 (en) |
| DK (1) | DK1562603T3 (en) |
| EA (1) | EA008665B1 (en) |
| EC (1) | ECSP055774A (en) |
| ES (1) | ES2326878T7 (en) |
| FR (1) | FR14C0049I2 (en) |
| HR (1) | HRP20050432B1 (en) |
| HU (1) | HUS1400011I1 (en) |
| IL (1) | IL167900A (en) |
| LT (1) | LTC1562603I2 (en) |
| LU (1) | LU92433I2 (en) |
| ME (1) | ME00354B (en) |
| MX (1) | MXPA05005081A (en) |
| MY (1) | MY136034A (en) |
| NL (1) | NL300650I2 (en) |
| NO (2) | NO334314B1 (en) |
| NZ (1) | NZ540661A (en) |
| PE (1) | PE20040694A1 (en) |
| PL (1) | PL212238B1 (en) |
| PT (1) | PT1562603E (en) |
| RS (1) | RS51607B (en) |
| SI (1) | SI1562603T1 (en) |
| TW (1) | TWI343812B (en) |
| UA (1) | UA81276C2 (en) |
| WO (1) | WO2004045618A2 (en) |
| ZA (1) | ZA200502246B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO337714B1 (en) * | 2004-04-22 | 2016-06-06 | Boehringer Ingelheim Int | Drug combinations containing benzoxazines and their use in the treatment of respiratory disorders |
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|---|---|---|---|---|
| US7056916B2 (en) | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
| DE102004019539A1 (en) * | 2004-04-22 | 2005-11-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New drugs for the treatment of respiratory diseases |
| EP1789394A1 (en) * | 2004-05-13 | 2007-05-30 | Boehringer Ingelheim International Gmbh | Hydroxy-substituted benzo-condensed heterocycles for use as beta agonists in the treatment of respiratory diseases |
| DE102004024451A1 (en) * | 2004-05-14 | 2005-12-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder formulations for inhalation containing enantiomerically pure beta agonists |
| US7745621B2 (en) | 2004-05-14 | 2010-06-29 | Boehringer Ingelheim International Gmbh | Long acting bronchodilators for the treatment of respiratory diseases |
| DE102004024453A1 (en) * | 2004-05-14 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New long-acting bronchodilators for the treatment of respiratory diseases |
| US7220742B2 (en) | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
| US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
| DE102004024452A1 (en) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for the inhalation of beta agonists |
| DE102004024454A1 (en) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel enantiomerically pure beta agonists, process for their preparation and their use as pharmaceuticals |
| GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
| DE102004045648A1 (en) * | 2004-09-21 | 2006-03-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New betamimetics for the treatment of respiratory diseases |
| GT200500281A (en) | 2004-10-22 | 2006-04-24 | Novartis Ag | ORGANIC COMPOUNDS. |
| GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
| GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
| DE102005007654A1 (en) * | 2005-02-19 | 2006-08-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New long-acting betamimetics for the treatment of respiratory diseases |
| GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
| GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
| DE102005030733A1 (en) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient |
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| US20070088030A1 (en) * | 2005-10-10 | 2007-04-19 | Barbara Niklaus-Humke | Aerosol formulations for the inhalation of beta-agonists |
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| GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
| JP2009526817A (en) * | 2006-02-16 | 2009-07-23 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pharmaceutical composition for the treatment of respiratory diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3134590A1 (en) * | 1981-09-01 | 1983-03-10 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW BENZO HETEROCYCLES |
| US4460581A (en) | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
| DE3743265A1 (en) * | 1987-12-19 | 1989-06-29 | Boehringer Ingelheim Kg | NEW AMMONIUM COMPOUNDS, THEIR MANUFACTURE AND USE |
| WO2001083462A1 (en) * | 2000-04-27 | 2001-11-08 | Boehringer Ingelheim Pharma Kg | Novel, slow-acting betamimetics, a method for their production and their use as medicaments |
-
2002
- 2002-11-15 DE DE10253282A patent/DE10253282A1/en not_active Withdrawn
-
2003
- 2003-11-11 CA CA2506082A patent/CA2506082C/en not_active Expired - Lifetime
- 2003-11-11 EA EA200500715A patent/EA008665B1/en active Protection Beyond IP Right Term
- 2003-11-11 SI SI200331634T patent/SI1562603T1/en unknown
- 2003-11-11 ME MEP-2008-536A patent/ME00354B/en unknown
- 2003-11-11 AU AU2003285326A patent/AU2003285326B2/en active Active
- 2003-11-11 KR KR1020057008679A patent/KR101092247B1/en not_active Expired - Lifetime
- 2003-11-11 DK DK03778312T patent/DK1562603T3/en active
- 2003-11-11 CN CN201010004697A patent/CN101817800A/en active Pending
- 2003-11-11 EP EP03778312.3A patent/EP1562603B3/en not_active Expired - Lifetime
- 2003-11-11 ES ES03778312.3T patent/ES2326878T7/en active Active
- 2003-11-11 CN CN200910266327A patent/CN101735166A/en active Pending
- 2003-11-11 UA UAA200505926A patent/UA81276C2/en unknown
- 2003-11-11 CN CNA2003801030945A patent/CN1713914A/en active Pending
- 2003-11-11 EP EP08169872A patent/EP2025338A1/en not_active Withdrawn
- 2003-11-11 NZ NZ540661A patent/NZ540661A/en not_active IP Right Cessation
- 2003-11-11 JP JP2004552561A patent/JP4317138B2/en not_active Expired - Lifetime
- 2003-11-11 BR BRPI0316264A patent/BRPI0316264B8/en active IP Right Grant
- 2003-11-11 PT PT03778312T patent/PT1562603E/en unknown
- 2003-11-11 HR HR20050432A patent/HRP20050432B1/en not_active IP Right Cessation
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO337714B1 (en) * | 2004-04-22 | 2016-06-06 | Boehringer Ingelheim Int | Drug combinations containing benzoxazines and their use in the treatment of respiratory disorders |
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