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NO161373C - Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater.

Info

Publication number
NO161373C
NO161373C NO854965A NO854965A NO161373C NO 161373 C NO161373 C NO 161373C NO 854965 A NO854965 A NO 854965A NO 854965 A NO854965 A NO 854965A NO 161373 C NO161373 C NO 161373C
Authority
NO
Norway
Prior art keywords
preparation
therapeutic active
pteridine derivatives
analogue procedure
active pteridine
Prior art date
Application number
NO854965A
Other languages
English (en)
Norwegian (no)
Other versions
NO161373B (no
NO854965L (no
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO854965L publication Critical patent/NO854965L/no
Publication of NO161373B publication Critical patent/NO161373B/no
Publication of NO161373C publication Critical patent/NO161373C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO854965A 1984-12-12 1985-12-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater. NO161373C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (3)

Publication Number Publication Date
NO854965L NO854965L (no) 1986-06-13
NO161373B NO161373B (no) 1989-05-02
NO161373C true NO161373C (no) 1989-08-09

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
NO854965A NO161373C (no) 1984-12-12 1985-12-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive pteridin-derivater.

Country Status (15)

Country Link
EP (1) EP0185259A3 (da)
JP (1) JPS61140585A (da)
AU (1) AU576924B2 (da)
CA (1) CA1252783A (da)
DE (1) DE3445298A1 (da)
DK (1) DK161327C (da)
ES (1) ES8707238A1 (da)
FI (1) FI82696C (da)
GR (1) GR852996B (da)
IL (1) IL77294A (da)
NO (1) NO161373C (da)
NZ (1) NZ214522A (da)
PH (1) PH24451A (da)
PT (1) PT81650B (da)
ZA (1) ZA859462B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
WO2003002064A2 (en) * 2001-06-28 2003-01-09 Essential Therapeutics, Inc. Fused pyrimidine dhfr inhibitors as antibacterials
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
ES2295897T3 (es) * 2003-08-29 2008-04-16 4 Aza Ip Nv Efectos inmunodepresores de derivados de pteridina.
CA2537224A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
AU2005221614A1 (en) * 2004-03-04 2005-09-22 Neurogen Corporation Arylalkylamino-substituted quinazoline analogues
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057645A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
KR101464384B1 (ko) * 2005-11-22 2014-11-21 쿠도스 파마슈티칼스 리미티드 mTOR 억제제로서 피리도피리미딘, 피라조피리미딘 및피리미도피리미딘 유도체
EP2032585B1 (de) 2006-05-24 2014-07-23 Boehringer Ingelheim International GmbH Substituierte pteridine als therapeutika
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
WO2008009078A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. 4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
US7902189B2 (en) 2006-08-23 2011-03-08 Astrazeneca Ab Compounds
CN102137860B (zh) 2008-06-20 2013-08-28 阿斯利康(瑞典)有限公司 吡啶并嘧啶化合物及其制备方法
EP3722297A1 (en) 2015-03-04 2020-10-14 Gilead Sciences, Inc. Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
EP3507288B1 (en) 2016-09-02 2020-08-26 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
PL3507276T3 (pl) 2016-09-02 2022-02-21 Gilead Sciences, Inc. Związki modulatory receptorów toll-podobnych
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (de) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS61140585A (ja) 1986-06-27
AU576924B2 (en) 1988-09-08
DK572685D0 (da) 1985-12-11
DK572685A (da) 1986-06-13
DE3445298A1 (de) 1986-06-12
NZ214522A (en) 1988-07-28
EP0185259A3 (de) 1989-03-01
CA1252783A (en) 1989-04-18
FI82696B (fi) 1990-12-31
FI854862A0 (fi) 1985-12-10
ES549806A0 (es) 1987-07-16
NO161373B (no) 1989-05-02
DK161327B (da) 1991-06-24
FI854862A (fi) 1986-06-13
NO854965L (no) 1986-06-13
ES8707238A1 (es) 1987-07-16
EP0185259A2 (de) 1986-06-25
AU5123285A (en) 1986-06-19
GR852996B (da) 1986-04-16
ZA859462B (en) 1987-07-29
FI82696C (fi) 1991-04-10
IL77294A (en) 1989-02-28
PH24451A (en) 1990-06-25
PT81650B (pt) 1988-04-21
PT81650A (de) 1986-01-01
DK161327C (da) 1991-12-09

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