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ZA859462B - New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions - Google Patents

New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions

Info

Publication number
ZA859462B
ZA859462B ZA859462A ZA859462A ZA859462B ZA 859462 B ZA859462 B ZA 859462B ZA 859462 A ZA859462 A ZA 859462A ZA 859462 A ZA859462 A ZA 859462A ZA 859462 B ZA859462 B ZA 859462B
Authority
ZA
South Africa
Prior art keywords
preparing
processes
pharmaceutical compositions
intermediate products
pteridines
Prior art date
Application number
ZA859462A
Other languages
English (en)
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA859462B publication Critical patent/ZA859462B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA859462A 1984-12-12 1985-12-11 New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions ZA859462B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (1)

Publication Number Publication Date
ZA859462B true ZA859462B (en) 1987-07-29

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA859462A ZA859462B (en) 1984-12-12 1985-12-11 New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions

Country Status (15)

Country Link
EP (1) EP0185259A3 (xx)
JP (1) JPS61140585A (xx)
AU (1) AU576924B2 (xx)
CA (1) CA1252783A (xx)
DE (1) DE3445298A1 (xx)
DK (1) DK161327C (xx)
ES (1) ES8707238A1 (xx)
FI (1) FI82696C (xx)
GR (1) GR852996B (xx)
IL (1) IL77294A (xx)
NO (1) NO161373C (xx)
NZ (1) NZ214522A (xx)
PH (1) PH24451A (xx)
PT (1) PT81650B (xx)
ZA (1) ZA859462B (xx)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
WO2003002064A2 (en) * 2001-06-28 2003-01-09 Essential Therapeutics, Inc. Fused pyrimidine dhfr inhibitors as antibacterials
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
ES2295897T3 (es) * 2003-08-29 2008-04-16 4 Aza Ip Nv Efectos inmunodepresores de derivados de pteridina.
CA2537224A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
AU2005221614A1 (en) * 2004-03-04 2005-09-22 Neurogen Corporation Arylalkylamino-substituted quinazoline analogues
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057645A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
KR101464384B1 (ko) * 2005-11-22 2014-11-21 쿠도스 파마슈티칼스 리미티드 ｍＴＯＲ 억제제로서 피리도피리미딘, 피라조피리미딘 및피리미도피리미딘 유도체
EP2032585B1 (de) 2006-05-24 2014-07-23 Boehringer Ingelheim International GmbH Substituierte pteridine als therapeutika
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
WO2008009078A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. 4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
US7902189B2 (en) 2006-08-23 2011-03-08 Astrazeneca Ab Compounds
CN102137860B (zh) 2008-06-20 2013-08-28 阿斯利康(瑞典)有限公司 吡啶并嘧啶化合物及其制备方法
EP3722297A1 (en) 2015-03-04 2020-10-14 Gilead Sciences, Inc. Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
EP3507288B1 (en) 2016-09-02 2020-08-26 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
PL3507276T3 (pl) 2016-09-02 2022-02-21 Gilead Sciences, Inc. Związki modulatory receptorów toll-podobnych
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (de) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS61140585A (ja) 1986-06-27
AU576924B2 (en) 1988-09-08
DK572685D0 (da) 1985-12-11
DK572685A (da) 1986-06-13
DE3445298A1 (de) 1986-06-12
NZ214522A (en) 1988-07-28
EP0185259A3 (de) 1989-03-01
CA1252783A (en) 1989-04-18
FI82696B (fi) 1990-12-31
FI854862A0 (fi) 1985-12-10
ES549806A0 (es) 1987-07-16
NO161373B (no) 1989-05-02
DK161327B (da) 1991-06-24
FI854862A (fi) 1986-06-13
NO854965L (no) 1986-06-13
ES8707238A1 (es) 1987-07-16
EP0185259A2 (de) 1986-06-25
AU5123285A (en) 1986-06-19
GR852996B (xx) 1986-04-16
FI82696C (fi) 1991-04-10
IL77294A (en) 1989-02-28
PH24451A (en) 1990-06-25
PT81650B (pt) 1988-04-21
PT81650A (de) 1986-01-01
NO161373C (no) 1989-08-09
DK161327C (da) 1991-12-09

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