DK572685A - Hidtil ukendte pteridiner, deres fremstilling og anvendelse - Google Patents

Hidtil ukendte pteridiner, deres fremstilling og anvendelse Download PDF

Info

Publication number: DK572685A
Authority: DK; Denmark
Prior art keywords: pteridines; unknown; preparation; unknown pteridines
Prior art date: 1984-12-12

Application number

DK572685A

Other languages

English (en)

Other versions

DK572685D0 (da

DK161327B (da

DK161327C (da

Inventor

Josef Roch

Armin Heckel

Josef Nickl

Erich Mueller

Berthold Narr

Rainer Zimmermann

Weisenberger Hans

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-12

Filing date

1985-12-11

Publication date

1986-06-13

1985-12-11 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1985-12-11 Publication of DK572685D0 publication Critical patent/DK572685D0/da

1986-06-13 Publication of DK572685A publication Critical patent/DK572685A/da

1991-06-24 Publication of DK161327B publication Critical patent/DK161327B/da

1991-12-09 Application granted granted Critical

1991-12-09 Publication of DK161327C publication Critical patent/DK161327C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DK572685A 1984-12-12 1985-12-11 Substituerede 2-piperazinopteridiner, fremgangsmaade til fremstilling deraf samt laegemidler indeholdende forbindelserne DK161327C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3445298		1984-12-12
DE19843445298 DE3445298A1 (de)	1984-12-12	1984-12-12	Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (4)

Publication Number	Publication Date
DK572685D0 DK572685D0 (da)	1985-12-11
DK572685A true DK572685A (da)	1986-06-13
DK161327B DK161327B (da)	1991-06-24
DK161327C DK161327C (da)	1991-12-09

Family

ID=6252576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK572685A DK161327C (da)	1984-12-12	1985-12-11	Substituerede 2-piperazinopteridiner, fremgangsmaade til fremstilling deraf samt laegemidler indeholdende forbindelserne

Country Status (15)

Country	Link
EP (1)	EP0185259A3 (da)
JP (1)	JPS61140585A (da)
AU (1)	AU576924B2 (da)
CA (1)	CA1252783A (da)
DE (1)	DE3445298A1 (da)
DK (1)	DK161327C (da)
ES (1)	ES8707238A1 (da)
FI (1)	FI82696C (da)
GR (1)	GR852996B (da)
IL (1)	IL77294A (da)
NO (1)	NO161373C (da)
NZ (1)	NZ214522A (da)
PH (1)	PH24451A (da)
PT (1)	PT81650B (da)
ZA (1)	ZA859462B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7276506B2 (en)	1998-12-28	2007-10-02	4 Aza Bioscience Nv	Immunosuppressive effects of pteridine derivatives
WO2003002064A2 (en) *	2001-06-28	2003-01-09	Essential Therapeutics, Inc.	Fused pyrimidine dhfr inhibitors as antibacterials
DE10202468A1 (de) *	2002-01-23	2004-09-30	Faustus Forschungs Cie. Translational Cancer Research Gmbh	Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
ES2295897T3 (es) *	2003-08-29	2008-04-16	4 Aza Ip Nv	Efectos inmunodepresores de derivados de pteridina.
CA2537224A1 (en) *	2003-10-17	2005-05-06	4 Aza Bioscience Nv	Heterocycle-substituted pteridine derivatives and their use in therapy
GB2407089A (en) *	2003-10-17	2005-04-20	4 Aza Bioscience Nv	Pteridine derivatives
AU2005221614A1 (en) *	2004-03-04	2005-09-22	Neurogen Corporation	Arylalkylamino-substituted quinazoline analogues
DE102004057595A1 (de)	2004-11-29	2006-06-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de)	2004-11-29	2006-06-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057645A1 (de)	2004-11-29	2006-06-01	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de)	2004-11-29	2006-06-08	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
RU2445315C2 (ru) *	2005-11-22	2012-03-20	Кудос Фармасьютиклз Лимитед	ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
KR101464384B1 (ko) *	2005-11-22	2014-11-21	쿠도스 파마슈티칼스 리미티드	ｍＴＯＲ 억제제로서 피리도피리미딘, 피라조피리미딘 및피리미도피리미딘 유도체
EP2032585B1 (de)	2006-05-24	2014-07-23	Boehringer Ingelheim International GmbH	Substituierte pteridine als therapeutika
WO2008009079A2 (en)	2006-07-20	2008-01-24	Gilead Sciences, Inc.	Substituted pteridines useful for the treatment and prevention of viral infections
WO2008009078A2 (en)	2006-07-20	2008-01-24	Gilead Sciences, Inc.	4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
US7902189B2 (en)	2006-08-23	2011-03-08	Astrazeneca Ab	Compounds
CN102137860B (zh)	2008-06-20	2013-08-28	阿斯利康(瑞典)有限公司	吡啶并嘧啶化合物及其制备方法
EP3722297A1 (en)	2015-03-04	2020-10-14	Gilead Sciences, Inc.	Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
EP3507288B1 (en)	2016-09-02	2020-08-26	Gilead Sciences, Inc.	4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
PL3507276T3 (pl)	2016-09-02	2022-02-21	Gilead Sciences, Inc.	Związki modulatory receptorów toll-podobnych
TWI751516B (zh)	2019-04-17	2022-01-01	美商基利科學股份有限公司	類鐸受體調節劑之固體形式
TWI751517B (zh)	2019-04-17	2022-01-01	美商基利科學股份有限公司	類鐸受體調節劑之固體形式
TW202115056A (zh)	2019-06-28	2021-04-16	美商基利科學股份有限公司	類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3159628A (en) *	1962-05-28	1964-12-01	Smith Kline French Lab	Pteridine-5-oxide derivatives
DE3323932A1 (de) *	1983-07-02	1985-01-10	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

1984
- 1984-12-12 DE DE19843445298 patent/DE3445298A1/de not_active Withdrawn
1985
- 1985-12-05 EP EP85115459A patent/EP0185259A3/de not_active Ceased
- 1985-12-10 FI FI854862A patent/FI82696C/fi not_active IP Right Cessation
- 1985-12-11 ZA ZA859462A patent/ZA859462B/xx unknown
- 1985-12-11 JP JP60278859A patent/JPS61140585A/ja active Pending
- 1985-12-11 PT PT81650A patent/PT81650B/pt not_active IP Right Cessation
- 1985-12-11 NZ NZ214522A patent/NZ214522A/xx unknown
- 1985-12-11 NO NO854965A patent/NO161373C/no unknown
- 1985-12-11 PH PH33161A patent/PH24451A/en unknown
- 1985-12-11 IL IL77294A patent/IL77294A/xx unknown
- 1985-12-11 DK DK572685A patent/DK161327C/da not_active IP Right Cessation
- 1985-12-11 CA CA000497336A patent/CA1252783A/en not_active Expired
- 1985-12-11 ES ES549806A patent/ES8707238A1/es not_active Expired
- 1985-12-12 AU AU51232/85A patent/AU576924B2/en not_active Ceased
- 1985-12-12 GR GR852996A patent/GR852996B/el unknown

Also Published As

Publication number	Publication date
JPS61140585A (ja)	1986-06-27
AU576924B2 (en)	1988-09-08
DK572685D0 (da)	1985-12-11
DE3445298A1 (de)	1986-06-12
NZ214522A (en)	1988-07-28
EP0185259A3 (de)	1989-03-01
CA1252783A (en)	1989-04-18
FI82696B (fi)	1990-12-31
FI854862A0 (fi)	1985-12-10
ES549806A0 (es)	1987-07-16
NO161373B (no)	1989-05-02
DK161327B (da)	1991-06-24
FI854862A (fi)	1986-06-13
NO854965L (no)	1986-06-13
ES8707238A1 (es)	1987-07-16
EP0185259A2 (de)	1986-06-25
AU5123285A (en)	1986-06-19
GR852996B (da)	1986-04-16
ZA859462B (en)	1987-07-29
FI82696C (fi)	1991-04-10
IL77294A (en)	1989-02-28
PH24451A (en)	1990-06-25
PT81650B (pt)	1988-04-21
PT81650A (de)	1986-01-01
NO161373C (no)	1989-08-09
DK161327C (da)	1991-12-09

Publication	Publication Date	Title
DK572685A (da)	1986-06-13	Hidtil ukendte pteridiner, deres fremstilling og anvendelse
DK546186D0 (da)	1986-11-14	Substituerede benzylethere, deres fremstilling og anvendelse
DK129386D0 (da)	1986-03-20	Iodpropargylethere, deres fremstilling og anvendelse
DK354687D0 (da)	1987-07-09	7-acyloxy-6-aminoacyloxypolyoxylabdaner, deres fremstilling og anvendelse
DK519586A (da)	1987-05-01	1-aryl-4-nitro-pyrazoler, deres fremstilling og anvendelse
DK535287A (da)	1988-04-15	Piperidin-4-yl-tetracycliske benzodiazepiner, deres fremstilling og anvendelse
DK28685D0 (da)	1985-01-22	Azolyl-aryl-alkanol-derivater, deres fremstilling og anvendelse
DK385185D0 (da)	1985-08-23	Substituerede phenylurinstoffer, deres fremstilling og anvendelse
DK380286D0 (da)	1986-08-08	Sulfonamider, deres fremstilling og anvendelse
DK396886A (da)	1987-02-22	Gem-dihalogen-1,8-diamino-4-azaoctaner, deres fremstilling og anvendelse
DK617886D0 (da)	1986-12-19	1-aryl-pyrazoler, deres fremstilling og anvendelse
DK289287D0 (da)	1987-06-04	1-phenylalkylimidazol-4- og/eller -5-carboxamider samt deres fremstiling og anvendelse
DK377786D0 (da)	1986-08-07	1-aryl-5-hydrazino-pyrazoler, deres fremstilling og anvendelse
DK136985D0 (da)	1985-03-26	Sulfamoylguanidin-derivater, deres fremstilling og anvendelse
DK675687A (da)	1988-06-23	Substituerede n-methylisoxazolidiner, deres fremstilling og anvendelse
DK625287A (da)	1988-05-29	1-aryloxy-3-amino-2-propanoler, deres fremstilling og anvendelse
DK558582A (da)	1983-06-19	Hidtil ukendte ergotanilider, deres fremstilling og anvendelse
DK126987A (da)	1987-09-14	Pyrimidoindoler, deres fremstilling og anvendelse
DK393986A (da)	1987-02-21	Lactamamider, deres fremstilling og anvendelse
DK136885A (da)	1985-09-28	Thiatriazin-derivater, deres fremstilling og anvendelse
DK451486A (da)	1987-03-24	Alkenylazoler, deres fremstilling og anvendelse
DK564986D0 (da)	1986-11-25	Thienylurinstofderivater, deres fremstilling og anvendelse
DK452087A (da)	1988-03-01	3-brom-2,6-dimethoxybenzamider, deres fremstilling og anvendelse
DK540786D0 (da)	1986-11-12	2-hydroxybenzamider, deres fremstilling og anvendelse
DK136785A (da)	1985-09-28	Thiatriazin-derivater, deres fremstilling og anvendelse

Legal Events

Date	Code	Title	Description
1992-08-24	PBP	Patent lapsed