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NL8700966A - Nieuwe ergoleenderivaten, farmaceutische preparaten met dergelijke derivaten erin, alsmede werkwijze voor de bereiding ervan. - Google Patents

Nieuwe ergoleenderivaten, farmaceutische preparaten met dergelijke derivaten erin, alsmede werkwijze voor de bereiding ervan. Download PDF

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Publication number
NL8700966A
NL8700966A NL8700966A NL8700966A NL8700966A NL 8700966 A NL8700966 A NL 8700966A NL 8700966 A NL8700966 A NL 8700966A NL 8700966 A NL8700966 A NL 8700966A NL 8700966 A NL8700966 A NL 8700966A
Authority
NL
Netherlands
Prior art keywords
formula
derivative
group
halogen
acyl
Prior art date
Application number
NL8700966A
Other languages
English (en)
Dutch (nl)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NL8700966A publication Critical patent/NL8700966A/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NL8700966A 1986-04-25 1987-04-24 Nieuwe ergoleenderivaten, farmaceutische preparaten met dergelijke derivaten erin, alsmede werkwijze voor de bereiding ervan. NL8700966A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU861719A HU196598B (en) 1986-04-25 1986-04-25 Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
HU171986 1986-04-25

Publications (1)

Publication Number Publication Date
NL8700966A true NL8700966A (nl) 1987-11-16

Family

ID=10955843

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8700966A NL8700966A (nl) 1986-04-25 1987-04-24 Nieuwe ergoleenderivaten, farmaceutische preparaten met dergelijke derivaten erin, alsmede werkwijze voor de bereiding ervan.

Country Status (30)

Country Link
US (1) US4859682A (pt)
JP (1) JPS62258379A (pt)
KR (1) KR920008167B1 (pt)
CN (1) CN87102944A (pt)
AT (1) AT391472B (pt)
AU (1) AU592637B2 (pt)
BE (1) BE1001159A4 (pt)
CH (1) CH669791A5 (pt)
CS (1) CS268534B2 (pt)
DD (1) DD256133A5 (pt)
DE (1) DE3713768A1 (pt)
DK (1) DK208887A (pt)
EG (1) EG18272A (pt)
ES (1) ES2007339A6 (pt)
FI (1) FI871128A (pt)
FR (1) FR2597869B1 (pt)
GB (1) GB2189487B (pt)
GR (1) GR870645B (pt)
HU (1) HU196598B (pt)
IL (1) IL82324A0 (pt)
IN (1) IN165245B (pt)
IT (1) IT1203976B (pt)
LU (1) LU86853A1 (pt)
NL (1) NL8700966A (pt)
NO (1) NO165800C (pt)
PL (1) PL152619B1 (pt)
PT (1) PT84739B (pt)
SE (1) SE466401B (pt)
SU (1) SU1500161A3 (pt)
ZA (1) ZA872931B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
KR20040104677A (ko) * 2002-04-30 2004-12-10 비오갈 기오기스제르갸르 알티. 신규의 온단세트론 결정 형태, 그 제조 방법, 그 신규의결정 형태를 함유하는 약학 조성물 및 이들을 이용한구역질 치료 방법
US20240343692A1 (en) * 2021-08-09 2024-10-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Selective psychedelic compounds

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE237837C (pt) *
DE1936410A1 (de) * 1969-07-17 1971-02-11 Hoechst Ag O-Acyl-lysergole und Verfahren zu ihrer Herstellung
AR206772A1 (es) * 1972-07-21 1976-08-23 Lilly Co Eli Procedimiento para preparar una nueva d-2-halo-6-metil-8-ciano(carboxamido)metil ergolina
US3992385A (en) * 1975-01-20 1976-11-16 Eli Lilly And Company 2,3-Dihydroergolines
CH619709A5 (en) * 1975-03-14 1980-10-15 Siphar Sa Process for the preparation of carbamates of 2-halogenoergolines and 2-halogenoergolenes
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
US4035094A (en) * 1976-03-11 1977-07-12 Trw Inc. Ball and socket joint
DK75177A (da) * 1976-04-27 1977-10-28 Sandoz Ag Fremgangsmade til fremstilling af prostaglandiner
US4098790A (en) * 1976-09-15 1978-07-04 Eli Lilly And Company Ergoline chlorination process
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DD237837A1 (de) * 1983-11-29 1986-07-30 1086 Berlin,Otto-Nuscke-Str. 2/23,Dd Verfahren zur herstellung von 2-bromergolinen
DE3403067A1 (de) * 1984-01-30 1985-08-14 Eckart Prof. Dr. 6500 Mainz Eich Ergolin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3413657A1 (de) * 1984-04-09 1985-10-17 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergoline
HU193781B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof
US4782152A (en) * 1985-08-16 1988-11-01 Eli Lilly And Company Decyanation of pergolide intermediate
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives

Also Published As

Publication number Publication date
GB2189487B (en) 1990-05-23
PL265357A1 (en) 1988-07-21
IL82324A0 (en) 1987-10-30
NO165800C (no) 1991-04-10
FI871128A (fi) 1987-10-26
AU7194587A (en) 1987-10-29
ES2007339A6 (es) 1989-06-16
EG18272A (en) 1993-04-30
GB8709893D0 (en) 1987-06-03
FI871128A0 (fi) 1987-03-13
SU1500161A3 (ru) 1989-08-07
KR870010051A (ko) 1987-11-30
AU592637B2 (en) 1990-01-18
CS268534B2 (en) 1990-03-14
DK208887D0 (da) 1987-04-24
CN87102944A (zh) 1987-11-25
LU86853A1 (de) 1987-08-12
SE8701700L (sv) 1987-10-26
IN165245B (pt) 1989-09-09
FR2597869B1 (fr) 1991-04-26
GR870645B (en) 1987-08-28
CS292087A2 (en) 1989-06-13
PT84739A (en) 1987-05-01
NO165800B (no) 1991-01-02
DE3713768A1 (de) 1987-10-29
IT8720271A0 (it) 1987-04-24
ATA102287A (de) 1990-04-15
PL152619B1 (en) 1991-01-31
SE8701700D0 (sv) 1987-04-24
IT1203976B (it) 1989-02-23
JPH0462316B2 (pt) 1992-10-05
FR2597869A1 (fr) 1987-10-30
US4859682A (en) 1989-08-22
JPS62258379A (ja) 1987-11-10
SE466401B (sv) 1992-02-10
NO871721L (no) 1987-10-26
PT84739B (pt) 1989-12-29
KR920008167B1 (ko) 1992-09-24
BE1001159A4 (fr) 1989-08-01
AT391472B (de) 1990-10-10
CH669791A5 (pt) 1989-04-14
DK208887A (da) 1987-10-26
ZA872931B (pt) 1987-10-19
GB2189487A (en) 1987-10-28
NO871721D0 (no) 1987-04-24
DD256133A5 (de) 1988-04-27
HU196598B (en) 1988-12-28

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BV The patent application has lapsed