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MX9701292A - Compuestos espiro-azabiciclicos utiles en la terapia. - Google Patents

Compuestos espiro-azabiciclicos utiles en la terapia.

Info

Publication number
MX9701292A
MX9701292A MX9701292A MX9701292A MX9701292A MX 9701292 A MX9701292 A MX 9701292A MX 9701292 A MX9701292 A MX 9701292A MX 9701292 A MX9701292 A MX 9701292A MX 9701292 A MX9701292 A MX 9701292A
Authority
MX
Mexico
Prior art keywords
therapy
spiro
compounds useful
azabicyclic compounds
formula
Prior art date
Application number
MX9701292A
Other languages
English (en)
Inventor
Michael Balestra
John Charles Gordon
Ronald Conrad Griffith
Robert John Murray
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9417084A external-priority patent/GB9417084D0/en
Priority claimed from GBGB9504627.2A external-priority patent/GB9504627D0/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of MX9701292A publication Critical patent/MX9701292A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se proporciona los nuevos compuestos de la formula (I), en donde R representa al hidrogeno o metilo; y n representa 1 o 2; o una sal de adicion ácida aceptable en forma farmacéutica de éste, junto con los procesos para la preparacion deéstos, las composiciones que los contienen y su uso en la terapia. Los compuestos (I) se supone que son utiles en el tratamiento de las enfermedades psicoticas, las enfermedades del deterioro y la ansiedad.
MX9701292A 1994-08-24 1995-08-22 Compuestos espiro-azabiciclicos utiles en la terapia. MX9701292A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9417084A GB9417084D0 (en) 1994-08-24 1994-08-24 Compounds useful in therapy
GBGB9504627.2A GB9504627D0 (en) 1995-03-08 1995-03-08 Compounds for use in therapy
PCT/SE1995/000937 WO1996006098A1 (en) 1994-08-24 1995-08-22 Spiro-azabicyclic compounds useful in therapy

Publications (1)

Publication Number Publication Date
MX9701292A true MX9701292A (es) 1997-05-31

Family

ID=26305509

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9701292A MX9701292A (es) 1994-08-24 1995-08-22 Compuestos espiro-azabiciclicos utiles en la terapia.

Country Status (34)

Country Link
US (2) US5902814A (es)
EP (1) EP0777671B1 (es)
JP (1) JP3708962B2 (es)
KR (1) KR100366331B1 (es)
CN (2) CN1056846C (es)
AR (1) AR031828A2 (es)
AT (1) ATE192157T1 (es)
AU (1) AU690735B2 (es)
BR (1) BR9508751A (es)
CA (1) CA2196995C (es)
CZ (1) CZ289512B6 (es)
DE (1) DE69516524T2 (es)
DK (1) DK0777671T3 (es)
EE (1) EE03399B1 (es)
EG (1) EG24222A (es)
ES (1) ES2145922T3 (es)
FI (1) FI112868B (es)
GR (1) GR3033878T3 (es)
HK (1) HK1010370A1 (es)
HU (1) HUT77352A (es)
IL (1) IL115039A (es)
IS (1) IS1852B (es)
MX (1) MX9701292A (es)
NO (1) NO307707B1 (es)
NZ (1) NZ292289A (es)
PL (1) PL183933B1 (es)
PT (1) PT777671E (es)
RU (1) RU2148058C1 (es)
SA (1) SA95160370B1 (es)
SK (1) SK282366B6 (es)
TR (1) TR199501053A2 (es)
TW (1) TW397837B (es)
UA (1) UA54375C2 (es)
WO (1) WO1996006098A1 (es)

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Also Published As

Publication number Publication date
AU3401895A (en) 1996-03-14
AU690735B2 (en) 1998-04-30
DK0777671T3 (da) 2000-07-24
IS4424A (is) 1997-02-03
NO307707B1 (no) 2000-05-15
CN1099419C (zh) 2003-01-22
CA2196995C (en) 2008-05-13
EP0777671A1 (en) 1997-06-11
JP3708962B2 (ja) 2005-10-19
IS1852B (is) 2003-02-21
NO970800D0 (no) 1997-02-21
ATE192157T1 (de) 2000-05-15
RU2148058C1 (ru) 2000-04-27
BR9508751A (pt) 1997-08-12
TW397837B (en) 2000-07-11
WO1996006098A1 (en) 1996-02-29
US6051581A (en) 2000-04-18
EE9700039A (et) 1997-08-15
PL318760A1 (en) 1997-07-07
CN1159808A (zh) 1997-09-17
CZ39297A3 (en) 1997-12-17
CN1284505A (zh) 2001-02-21
CA2196995A1 (en) 1996-02-29
IL115039A (en) 2001-08-26
ES2145922T3 (es) 2000-07-16
HK1010370A1 (en) 1999-06-17
US5902814A (en) 1999-05-11
FI970762A (fi) 1997-02-24
GR3033878T3 (en) 2000-11-30
HUT77352A (hu) 1998-03-30
EG24222A (en) 2008-11-10
NO970800L (no) 1997-02-21
DE69516524D1 (de) 2000-05-31
IL115039A0 (en) 1995-12-08
KR100366331B1 (ko) 2003-04-10
AR031828A2 (es) 2003-10-08
PT777671E (pt) 2000-08-31
NZ292289A (en) 1998-05-27
DE69516524T2 (de) 2001-01-18
CN1056846C (zh) 2000-09-27
FI112868B (fi) 2004-01-30
JPH10504561A (ja) 1998-05-06
CZ289512B6 (cs) 2002-02-13
EP0777671B1 (en) 2000-04-26
UA54375C2 (uk) 2003-03-17
TR199501053A2 (tr) 1996-06-21
SK282366B6 (sk) 2002-01-07
EE03399B1 (et) 2001-04-16
SA95160370B1 (ar) 2006-06-04
SK21697A3 (en) 1997-09-10
FI970762A0 (fi) 1997-02-24
PL183933B1 (pl) 2002-08-30

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