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MX9700535A - Formulaciones de peroxido de cetona ciclico. - Google Patents

Formulaciones de peroxido de cetona ciclico.

Info

Publication number
MX9700535A
MX9700535A MX9700535A MX9700535A MX9700535A MX 9700535 A MX9700535 A MX 9700535A MX 9700535 A MX9700535 A MX 9700535A MX 9700535 A MX9700535 A MX 9700535A MX 9700535 A MX9700535 A MX 9700535A
Authority
MX
Mexico
Prior art keywords
cyclic ketone
ketone peroxide
peroxides
formulations
percent
Prior art date
Application number
MX9700535A
Other languages
English (en)
Inventor
Reinder Torenbeek
John Meijer
Andreas Herman Hogt
Gerrit Bekendam
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8217055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9700535(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of MX9700535A publication Critical patent/MX9700535A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D323/00Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25Component parts, details or accessories; Auxiliary operations
    • B29C48/92Measuring, controlling or regulating
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D323/00Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
    • C07D323/04Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00Polymerisation catalysts
    • C08F4/28Oxygen or compounds releasing free oxygen
    • C08F4/32Organic compounds
    • C08F4/38Mixtures of peroxy-compounds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/50Partial depolymerisation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/04Oxygen-containing compounds
    • C08K5/14Peroxides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C2948/00Indexing scheme relating to extrusion moulding
    • B29C2948/92Measuring, controlling or regulating
    • B29C2948/92504Controlled parameter
    • B29C2948/92704Temperature
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/022Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the choice of material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/25Component parts, details or accessories; Auxiliary operations
    • B29C48/36Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die
    • B29C48/395Means for plasticising or homogenising the moulding material or forcing it through the nozzle or die using screws surrounded by a cooperating barrel, e.g. single screw extruders
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00Chemical modification of a polymer
    • C08F2810/10Chemical modification of a polymer including a reactive processing step which leads, inter alia, to morphological and/or rheological modifications, e.g. visbreaking

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Polymerization Catalysts (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)

Abstract

Se describe una composicion de peroxido de cetona cíclico transportable y estable en almacenamiento que consta de 1.0-90% en peso de uno o más peroxidos de cetona cíclicos y 10-99% en peso de uno o más diluyentes seleccionados del grupo que consta de flemetizadores líquidos para los peroxidos de cetona cíclicos, plastificadores, vehículos poliméricos solidos, soportes inorgánicos, peroxidos orgánicos y mezclas de los mismos; también se describe el uso de estas formulaciones de peroxido de cetona cíclico en la modificacion de copolímeros; estas formulaciones proveen un grado sorprendente de modificacion de los polímeros en comparacion con sus contrapartes, los peroxidos de cetona no cíclicos.
MX9700535A 1994-07-21 1995-07-14 Formulaciones de peroxido de cetona ciclico. MX9700535A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94202136 1994-07-21
PCT/EP1995/002830 WO1996003397A1 (en) 1994-07-21 1995-07-14 Cyclic ketone peroxide formulations

Publications (1)

Publication Number Publication Date
MX9700535A true MX9700535A (es) 1997-04-30

Family

ID=8217055

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700535A MX9700535A (es) 1994-07-21 1995-07-14 Formulaciones de peroxido de cetona ciclico.

Country Status (17)

Country Link
US (1) US5808110A (es)
EP (1) EP0772609B1 (es)
JP (1) JP3794701B2 (es)
KR (1) KR100441557B1 (es)
CN (1) CN1068323C (es)
AT (1) ATE176910T1 (es)
AU (1) AU686466B2 (es)
BR (1) BR9508409A (es)
CA (1) CA2195537C (es)
CZ (1) CZ18497A3 (es)
DE (1) DE69507956T2 (es)
HU (1) HU216142B (es)
MX (1) MX9700535A (es)
PL (1) PL179659B1 (es)
RU (1) RU2154649C2 (es)
TW (1) TW414709B (es)
WO (1) WO1996003397A1 (es)

Families Citing this family (178)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR001122A1 (es) * 1995-03-06 1997-09-24 Akzo Nobel Nv Procedimiento de polímerizacion que utiliza una composición de peróxidos (co)polímero funcionalizadoobtenido por el proceso y uso de una composición de peróxidos
JP3991439B2 (ja) * 1997-08-04 2007-10-17 東レ株式会社 繊維強化プラスチックおよび繊維強化プラスチックの成形方法
WO1999032584A1 (en) * 1997-12-22 1999-07-01 Akzo Nobel N.V. Ignition improved fuels
GB9809108D0 (en) * 1998-04-30 1998-07-01 British Nuclear Fuels Plc Dimer
EP1121352B1 (en) * 1998-10-16 2003-04-16 Akzo Nobel N.V. Improved phlegmatization of cyclic ketone peroxides
JP2003527474A (ja) * 2000-03-16 2003-09-16 バーゼル、ポリオレフィン、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング ポリエチレンの製造方法
KR100819680B1 (ko) 2000-08-15 2008-04-04 아크조 노벨 엔.브이. 트리옥세판 화합물
EP1186618A1 (en) * 2000-09-08 2002-03-13 ATOFINA Research Controlled rheology polypropylene heterophasic copolymers
EP1216991A1 (en) * 2000-12-22 2002-06-26 Akzo Nobel N.V. Transportable and safely packaged organic peroxide formulations comprising reactive phlegmatizers
EP1219602A1 (en) 2000-12-29 2002-07-03 Akzo Nobel N.V. Methyl isopropyl ketone peroxide formulations and their use for curing unsaturated polyesters
WO2002053531A2 (en) * 2000-12-29 2002-07-11 Akzo Nobel N.V. Methyl propyl ketone peroxide formulations and their use for curing unsaturated polyesters
US6762208B2 (en) 2001-10-01 2004-07-13 Air Products And Chemicals, Inc. Alkane diol foam controlling agents
EP1312617A1 (en) 2001-11-14 2003-05-21 ATOFINA Research Impact strength polypropylene
US20040132101A1 (en) 2002-09-27 2004-07-08 Xencor Optimized Fc variants and methods for their generation
CA2490758C (en) 2002-07-15 2014-09-23 Genentech, Inc. Dosage form of recombinant humanized monoclonal antibody 2c4
CA2832136C (en) 2002-09-27 2015-11-17 Xencor Optimized fc variants and methods for their generation
US7252784B2 (en) 2002-12-06 2007-08-07 Akzo Nobel N.V. Cyclic ketone peroxide formulations
DE60323877D1 (de) * 2002-12-06 2008-11-13 Akzo Nobel Nv Formulierungen cylischer ketonperoxide
EP1447404A1 (en) * 2003-02-13 2004-08-18 Akzo Nobel N.V. Improved cyclic ketone peroxide compositions
KR101089113B1 (ko) 2003-02-13 2011-12-06 아크조 노벨 엔.브이. 저장 안정성 환형 케톤 퍼옥사이드 조성물
BR122018071968B8 (pt) 2003-11-06 2021-07-27 Seattle Genetics Inc conjugado de anticorpo-droga, composição farmacêutica, artigo de manufatura e uso de um conjugado de anticorpo-droga
CA2567520A1 (en) 2004-06-01 2005-12-15 Genentech, Inc. Maytansinoid-antibody conjugates
DE102004029732A1 (de) 2004-06-21 2006-01-19 Basf Ag Hilfsmittel enthaltend Cyclohexanpolycarbonsäurederivate
DK2471813T3 (en) 2004-07-15 2015-03-02 Xencor Inc Optimized Fc variants
KR101270829B1 (ko) 2004-09-23 2013-06-07 제넨테크, 인크. 시스테인 유전자조작 항체 및 접합체
JO3000B1 (ar) 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
DK1850874T3 (da) 2005-02-23 2013-11-11 Genentech Inc Forlængelse af tid til sygdomsprogression eller overlevelse for ovariecancer ved anvendelse af pertuzumab
PL1991601T3 (pl) 2006-03-03 2011-02-28 Akzo Nobel Chemicals Int Bv Sposób modyfikowania biodegradowalnych polimerów
WO2008022152A2 (en) 2006-08-14 2008-02-21 Xencor, Inc. Optimized antibodies that target cd19
EP2061906B1 (en) 2006-09-12 2011-08-31 Genentech, Inc. Methods and compositions for the diagnosis and treatment of lung cancer using pdgfra, kit or kdr gene as genetic marker
PL2132573T3 (pl) 2007-03-02 2014-09-30 Genentech Inc Prognozowanie odpowiedzi na inhibitor dimeryzacji HER oparte na niskiej ekspresji HER3
LT2176298T (lt) 2007-05-30 2018-04-10 Xencor, Inc. Būdai ir kompozicijos, skirti cd32b ekspresuojančių ląstelių slopinimui
EP2592156B1 (en) 2007-06-08 2016-04-20 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至her2結構域ii之抗體及其酸性變異體的組合物
DE102009002652A1 (de) * 2009-04-27 2010-10-28 BAM Bundesanstalt für Materialforschung und -prüfung Triacetontriperoxid und Diacetondiperoxid-Derivat, Verfahren zu ihrer Herstellung sowie ihre Verwendung
JP2012531492A (ja) * 2009-06-23 2012-12-10 ダウ グローバル テクノロジーズ エルエルシー 制御されたレオロジーのポリプロピレン
US9345661B2 (en) 2009-07-31 2016-05-24 Genentech, Inc. Subcutaneous anti-HER2 antibody formulations and uses thereof
MX2012006406A (es) 2009-12-04 2012-07-25 Genentech Inc Anticuerpos multiespecificos, analogos de anticuerpo, composiciones y metodos.
EP2523957A1 (en) 2010-01-12 2012-11-21 F. Hoffmann-La Roche AG Tricyclic heterocyclic compounds, compositions and methods of use thereof
WO2011113802A2 (en) 2010-03-17 2011-09-22 F. Hoffmann-La Roche Ag Imidazopyridine compounds, compositions and methods of use
WO2011120134A1 (en) 2010-03-29 2011-10-06 Zymeworks, Inc. Antibodies with enhanced or suppressed effector function
RU2012148699A (ru) 2010-04-16 2014-05-27 Дженентек, Инк. Foxo3a как прогностический биомаркер для эффективности ингибитора пути киназы pi3k/акт
WO2011146568A1 (en) 2010-05-19 2011-11-24 Genentech, Inc. Predicting response to a her inhibitor
EP2616072A1 (en) 2010-09-15 2013-07-24 F.Hoffmann-La Roche Ag Azabenzothiazole compounds, compositions and methods of use
WO2012065161A2 (en) 2010-11-12 2012-05-18 Scott & White Healthcare Antibodies to tumor endothelial marker 8
BR112013011520A2 (pt) 2010-11-19 2019-09-24 Hoffmann La Roche pirazolo piridinas e pirazolo piridinas e seu uso como inibidores de tyk2
WO2012085176A1 (en) 2010-12-23 2012-06-28 F. Hoffmann-La Roche Ag Tricyclic pyrazinone compounds, compositions and methods of use thereof as janus kinase inhibitors
FR2971510B1 (fr) * 2011-02-10 2013-03-22 Arkema France Polymerisation radicalaire de l'ethylene amorcee par des peroxydes organiques a haute productivite
US8609818B2 (en) 2011-03-10 2013-12-17 Omeros Corporation Generation of anti-FN14 monoclonal antibodies by ex-vivo accelerated antibody evolution
WO2013007765A1 (en) 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Fused tricyclic compounds for use as inhibitors of janus kinases
WO2013007768A1 (en) 2011-07-13 2013-01-17 F. Hoffmann-La Roche Ag Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
CA2843499A1 (en) 2011-08-12 2013-02-21 F. Hoffmann-La Roche Ag Indazole compounds, compositions and methods of use
JP5944994B2 (ja) 2011-08-12 2016-07-05 オメロス コーポレーション 抗fzd10モノクローナル抗体およびそれらの使用方法
EP2758397A1 (en) 2011-09-20 2014-07-30 F.Hoffmann-La Roche Ag Imidazopyridine compounds, compositions and methods of use
CN102584782A (zh) * 2011-12-31 2012-07-18 北京理工大学 过氧化丙酮四聚体的制备方法
MX2014010750A (es) 2012-03-08 2015-02-05 Halozyme Inc Anticuerpos receptores del factor de crecimiento anti-epidermico condicionalmente activos y metodos de uso de los mismos.
CA2865082A1 (en) 2012-03-27 2013-10-03 Genentech, Inc. Diagnosis and treatments relating to her3 inhibitors
PL2885349T3 (pl) * 2012-08-17 2018-10-31 Akzo Nobel Chemicals International B.V. Sposób utwardzania żywic termoutwardzalnych
CA2881550A1 (en) * 2012-08-17 2014-02-20 Akzo Nobel Chemicals International B.V. Process for curing thermoset resins
DE102013112821A1 (de) 2012-11-30 2014-06-05 Shell Internationale Research Maatschappij B.V. Kraftstoffzusammensetzungen
RU2655322C2 (ru) * 2012-12-05 2018-05-25 Акцо Нобель Кемикалз Интернэшнл Б.В. Мастербатч, содержащий циклический пероксид кетона
AR093663A1 (es) * 2012-12-05 2015-06-17 Akzo Nobel Chemicals Int Bv Lote maestro de peroxido basado en bioresina
AR093664A1 (es) * 2012-12-05 2015-06-17 Akzo Nobel Chemicals Int Bv Mezcla madre formada por un peroxido de cetona ciclico
PL2928951T3 (pl) * 2012-12-05 2019-05-31 Akzo Nobel Chemicals Int Bv Przedmieszka nadtlenkowa na bazie biożywicy
MY178296A (en) * 2012-12-05 2020-10-07 Akzo Nobel Chemicals Int Bv Peroxide masterbatch based on bioresin
US10316162B2 (en) * 2012-12-05 2019-06-11 Akzo Nobel Chemicals International B.V. Masterbatch comprising a cyclic ketone peroxide
JP6351616B2 (ja) 2012-12-21 2018-07-04 シエル・インターナシヨネイル・リサーチ・マーチヤツピイ・ベー・ウイShell Internationale Research Maatschappij Besloten Vennootshap 有機サンスクリーン化合物を含有する液体ディーゼル燃料組成物
JP6336598B2 (ja) 2013-09-05 2018-06-06 ジェネンテック, インコーポレイテッド 抗増殖性化合物
AR097894A1 (es) 2013-10-03 2016-04-20 Hoffmann La Roche Inhibidores terapéuticos de cdk8 o uso de los mismos
CN105658774B (zh) 2013-10-24 2018-04-06 国际壳牌研究有限公司 液体燃料组合物
WO2015091458A1 (en) 2013-12-16 2015-06-25 Shell Internationale Research Maatschappij B.V. Liquid fuel compositions
MX2016007965A (es) 2013-12-17 2016-10-28 Genentech Inc Terapia de combinacion que comprende agonistas de union a ox40 y antagonistas de union al eje pd-1.
RS59659B2 (sr) 2013-12-17 2023-08-31 Hoffmann La Roche Postupci lečenjа raka pomoću аntаgonistа koji vežu osovinu pd-1 i pomoću tаksаnа
RU2679146C2 (ru) 2014-03-11 2019-02-06 Акцо Нобель Кемикалз Интернэшнл Б.В. Состав циклического пероксида кетона
JP6588461B2 (ja) 2014-03-31 2019-10-09 ジェネンテック, インコーポレイテッド 抗血管新生剤及びox40結合アゴニストを含む併用療法
SG11201607969XA (en) 2014-03-31 2016-10-28 Genentech Inc Anti-ox40 antibodies and methods of use
EP2949732B1 (en) 2014-05-28 2018-06-20 Shell International Research Maatschappij B.V. Use of an oxanilide compound in a diesel fuel composition for the purpose of modifying the ignition delay and/or the burn period
FR3022251A1 (fr) * 2014-06-13 2015-12-18 Arkema France Solvant organique pour peroxydes
EP3189046B1 (en) 2014-09-05 2020-08-26 Genentech, Inc. Therapeutic compounds and uses thereof
CN107073125A (zh) 2014-09-19 2017-08-18 基因泰克公司 Cbp/ep300和bet抑制剂用于治疗癌症的用途
JP6783230B2 (ja) 2014-10-10 2020-11-11 ジェネンテック, インコーポレイテッド ヒストンデメチラーゼのインヒビターとしてのピロリドンアミド化合物
CA2966523A1 (en) 2014-11-03 2016-05-12 Genentech, Inc. Assays for detecting t cell immune subsets and methods of use thereof
AU2015343494A1 (en) 2014-11-06 2017-04-27 Genentech, Inc. Combination therapy comprising OX40 binding agonists and TIGIT inhibitors
MA40943A (fr) 2014-11-10 2017-09-19 Constellation Pharmaceuticals Inc Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
JP6639497B2 (ja) 2014-11-10 2020-02-05 ジェネンテック, インコーポレイテッド ブロモドメインインヒビターおよびその使用
MA40940A (fr) 2014-11-10 2017-09-19 Constellation Pharmaceuticals Inc Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
BR112017010198A2 (pt) 2014-11-17 2017-12-26 Genentech Inc terapia de combinação compreendendo agonistas de ligação a ox40 e antagonistas de ligação ao eixo de pd-1
CN107531690B (zh) 2014-11-27 2020-11-06 基因泰克公司 用作CBP和/或EP300抑制剂的4,5,6,7-四氢-1H-吡唑并[4,3-c]吡啶-3-胺化合物
MX2017006864A (es) 2014-12-23 2017-08-28 Genentech Inc Composiciones y métodos para tratar y diagnosticar cánceres resistentes a la quimioterapia.
WO2016109546A2 (en) 2014-12-30 2016-07-07 Genentech, Inc. Methods and compositions for prognosis and treatment of cancers
CN107406429B (zh) 2015-01-09 2021-07-06 基因泰克公司 哒嗪酮衍生物及其在治疗癌症中的用途
JP6855379B2 (ja) 2015-01-09 2021-04-07 ジェネンテック, インコーポレイテッド 癌の処置のためのヒストンデメチラーゼkdm2bのインヒビターとしての(ピペリジン−3−イル)(ナフタレン−2−イル)メタノン誘導体および関連化合物
EP3242875B1 (en) 2015-01-09 2022-02-23 Genentech, Inc. 4,5-dihydroimidazole derivatives and their use as histone demethylase (kdm2b) inhibitors
JP6709792B2 (ja) 2015-01-29 2020-06-17 ジェネンテック, インコーポレイテッド 治療用化合物およびその使用
EP3250552B1 (en) 2015-01-30 2019-03-27 Genentech, Inc. Therapeutic compounds and uses thereof
MA41598A (fr) 2015-02-25 2018-01-02 Constellation Pharmaceuticals Inc Composés thérapeutiques de pyridazine et leurs utilisations
AU2016246695A1 (en) 2015-04-07 2017-10-26 Genentech, Inc. Antigen binding complex having agonistic activity and methods of use
ES2789500T5 (es) 2015-05-29 2023-09-20 Hoffmann La Roche Procedimientos terapéuticos y de diagnóstico para el cáncer
AU2016274585A1 (en) 2015-06-08 2017-12-14 Genentech, Inc. Methods of treating cancer using anti-OX40 antibodies
CA2988420A1 (en) 2015-06-08 2016-12-15 Genentech, Inc. Methods of treating cancer using anti-ox40 antibodies and pd-1 axis binding antagonists
CA2986263A1 (en) 2015-06-17 2016-12-22 Genentech, Inc. Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
EP3341376B1 (en) 2015-08-26 2020-12-23 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Condensed tricyclic compounds as protein kinase inhibitors
EP3374471B1 (en) 2015-11-11 2020-10-28 Shell International Research Maatschappij B.V. Process for preparing a diesel fuel composition
MX2018008347A (es) 2016-01-08 2018-12-06 Hoffmann La Roche Metodos de tratamiento de canceres positivos para ace utilizando antagonistas de union a eje pd-1 y anticuerpos biespecificos anti-ace/anti-cd3.
EP3423596B1 (en) 2016-02-29 2022-09-28 Genentech, Inc. Therapeutic and diagnostic methods for cancer
KR20190003957A (ko) 2016-04-15 2019-01-10 제넨테크, 인크. 암 모니터링 및 치료 방법
ES2850428T3 (es) 2016-04-15 2021-08-30 Hoffmann La Roche Procedimientos de monitorización y tratamiento del cáncer
JP2019518426A (ja) 2016-04-15 2019-07-04 ジェネンテック, インコーポレイテッド がんの診断及び治療方法
WO2017194554A1 (en) 2016-05-10 2017-11-16 Inserm (Institut National De La Sante Et De La Recherche Medicale) Combinations therapies for the treatment of cancer
CN109476663B (zh) 2016-05-24 2021-11-09 基因泰克公司 用于治疗癌症的吡唑并吡啶衍生物
EP4067347B1 (en) 2016-05-24 2024-06-19 Genentech, Inc. Heterocyclic inhibitors of cbp/ep300 for the treatment of cancer
JP2019527037A (ja) 2016-06-08 2019-09-26 ジェネンテック, インコーポレイテッド がんのための診断及び治療方法
ES2963807T3 (es) 2016-06-08 2024-04-02 Xencor Inc Tratamiento de enfermedades relacionadas con la IgG4 con anticuerpos anti-CD19 de reticulación a CD32B
JP2019530434A (ja) 2016-08-05 2019-10-24 ジェネンテック, インコーポレイテッド アゴニスト活性を有する多価及び多重エピトープ抗体ならびに使用方法
CN109476748B (zh) 2016-08-08 2023-05-23 豪夫迈·罗氏有限公司 用于癌症的治疗和诊断方法
JP7579056B2 (ja) 2016-10-06 2024-11-07 ジェネンテック, インコーポレイテッド がんのための治療方法及び診断方法
WO2018077976A1 (en) 2016-10-27 2018-05-03 Shell Internationale Research Maatschappij B.V. Process for preparing an automotive gasoil
CN110267678A (zh) 2016-10-29 2019-09-20 霍夫曼-拉罗奇有限公司 抗mic抗体和使用方法
FR3060011B1 (fr) * 2016-12-08 2020-06-26 Arkema France Agent de durcissement pour durcir une resine de polymere
WO2018206729A1 (en) 2017-05-11 2018-11-15 Shell Internationale Research Maatschappij B.V. Process for preparing an automotive gas oil fraction
JP2020527351A (ja) 2017-07-21 2020-09-10 ジェネンテック, インコーポレイテッド がんの治療法及び診断法
EP3710001A4 (en) 2017-10-27 2021-07-14 University Of Virginia Patent Foundation COMPOUNDS AND PROCESSES FOR REGULATING, LIMITING OR INHIBITING THE EXPRESSION OF AVIL
EP3707510B1 (en) 2017-11-06 2024-06-26 F. Hoffmann-La Roche AG Diagnostic and therapeutic methods for cancer
BR112020018457A2 (pt) * 2018-03-13 2020-12-29 Nouryon Chemicals International B.V. Solução, formulação de peróxido, e processo de cura de resina radicalmente curável
CN108503885A (zh) * 2018-05-28 2018-09-07 广州印田新材料有限公司 一种含有酯类减敏剂的稳定的环酮过氧化物组合物
CN108586802A (zh) * 2018-05-28 2018-09-28 广州印田新材料有限公司 含有酯类减敏剂的稳定环酮过氧化物组合物的制备方法
KR20210024550A (ko) 2018-06-23 2021-03-05 제넨테크, 인크. Pd-1 축 결합 길항제, 백금 제제, 및 토포이소머라제 ii 억제제를 이용한 폐암 치료 방법
CN112368359B (zh) 2018-07-02 2023-03-28 国际壳牌研究有限公司 液体燃料组合物
EP3823611A1 (en) 2018-07-18 2021-05-26 Genentech, Inc. Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
TW202024023A (zh) 2018-09-03 2020-07-01 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法
JP2022501332A (ja) 2018-09-19 2022-01-06 ジェネンテック, インコーポレイテッド 膀胱がんの治療方法および診断方法
EP4249917A3 (en) 2018-09-21 2023-11-08 F. Hoffmann-La Roche AG Diagnostic methods for triple-negative breast cancer
KR20210079311A (ko) 2018-10-18 2021-06-29 제넨테크, 인크. 육종성 신장암에 대한 진단과 치료 방법
WO2020163589A1 (en) 2019-02-08 2020-08-13 Genentech, Inc. Diagnostic and therapeutic methods for cancer
EP3931220A1 (en) 2019-02-27 2022-01-05 F. Hoffmann-La Roche AG Dosing for treatment with anti-tigit and anti-cd20 or anti-cd38 antibodies
WO2020223233A1 (en) 2019-04-30 2020-11-05 Genentech, Inc. Prognostic and therapeutic methods for colorectal cancer
TW202108616A (zh) 2019-05-03 2021-03-01 美商建南德克公司 用抗pd-l1抗體治療癌症之方法
CN112300279A (zh) 2019-07-26 2021-02-02 上海复宏汉霖生物技术股份有限公司 针对抗cd73抗体和变体的方法和组合物
CR20220095A (es) 2019-09-04 2022-06-06 Genentech Inc Agentes de unión a cd8 y usos de los mismos
EP4034532A1 (en) 2019-09-26 2022-08-03 Exelixis, Inc. Pyridone compounds and methods of use in the modulation of a protein kinase
FR3101349B1 (fr) * 2019-09-27 2022-02-25 Arkema France Composition anhydre solide sous forme de poudre comprenant au moins un peroxyde organique, au moins un agent flegmatisant et au moins un liant et procédé préparation correspondant
KR20220070237A (ko) 2019-09-27 2022-05-30 제넨테크, 인크. 항-tigit 및 항-pd-l1 길항제 항체를 이용한 치료를 위한 투약
JP2023511472A (ja) 2019-10-29 2023-03-20 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト がんの治療のための二官能性化合物
IL292458A (en) 2019-11-06 2022-06-01 Genentech Inc Diagnostic and treatment methods for the treatment of hematological cancer
JP7629916B2 (ja) 2019-11-13 2025-02-14 ジェネンテック, インコーポレイテッド 治療用化合物および使用方法
AU2020403145A1 (en) 2019-12-13 2022-07-07 Genentech, Inc. Anti-Ly6G6D antibodies and methods of use
CN115315256A (zh) 2020-01-27 2022-11-08 基因泰克公司 用抗tigit拮抗剂抗体治疗癌症的方法
WO2022050954A1 (en) 2020-09-04 2022-03-10 Genentech, Inc. Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
WO2021194481A1 (en) 2020-03-24 2021-09-30 Genentech, Inc. Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
WO2021177980A1 (en) 2020-03-06 2021-09-10 Genentech, Inc. Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
WO2021202959A1 (en) 2020-04-03 2021-10-07 Genentech, Inc. Therapeutic and diagnostic methods for cancer
JP2023523450A (ja) 2020-04-28 2023-06-05 ジェネンテック, インコーポレイテッド 非小細胞肺がん免疫療法のための方法及び組成物
IL299039A (en) 2020-06-16 2023-02-01 Genentech Inc Methods and preparations for the treatment of triple-negative breast cancer
CN115916348A (zh) 2020-06-18 2023-04-04 基因泰克公司 使用抗tigit抗体和pd-1轴结合拮抗剂的治疗
JP2023531305A (ja) 2020-06-30 2023-07-21 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 術前補助療法後の固形癌患者の再発及び/又は死亡のリスクを予測するための方法。
US20230266322A1 (en) 2020-06-30 2023-08-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapy and radical surgery
US11787775B2 (en) 2020-07-24 2023-10-17 Genentech, Inc. Therapeutic compounds and methods of use
CN116568824A (zh) 2020-08-03 2023-08-08 基因泰克公司 淋巴瘤的诊断和治疗方法
EP4196612A1 (en) 2020-08-12 2023-06-21 Genentech, Inc. Diagnostic and therapeutic methods for cancer
MX2023003338A (es) 2020-09-23 2023-06-14 Erasca Inc Piridonas y pirimidonas tricíclicas.
TW202446417A (zh) 2020-10-05 2024-12-01 美商建南德克公司 用抗 fcrh5/抗 cd3 雙特異性抗體進行治療之給藥
US20230107642A1 (en) 2020-12-18 2023-04-06 Erasca, Inc. Tricyclic pyridones and pyrimidones
EP4291558A1 (en) 2021-02-12 2023-12-20 F. Hoffmann-La Roche AG Bicyclic tetrahydroazepine derivatives for the treatment of cancer
CA3211063A1 (en) 2021-02-19 2022-08-25 Exelixis, Inc. Pyridone compounds and methods of use
EP4347603A1 (en) 2021-05-25 2024-04-10 Erasca, Inc. Sulfur-containing heteroaromatic tricyclic kras inhibitors
US20240293558A1 (en) 2021-06-16 2024-09-05 Erasca, Inc. Kras inhibitor conjugates
TW202321261A (zh) 2021-08-10 2023-06-01 美商伊瑞斯卡公司 選擇性kras抑制劑
TW202332429A (zh) 2021-11-24 2023-08-16 美商建南德克公司 治療性化合物及其使用方法
AU2022450448A1 (en) 2022-04-01 2024-10-10 Genentech, Inc. Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
IL316738A (en) 2022-05-11 2024-12-01 Genentech Inc Dosage for treatment with anti-FCRH5/anti-CD3 bispecific antibodies
KR20250022049A (ko) 2022-06-07 2025-02-14 제넨테크, 인크. 항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법
CN119585308A (zh) 2022-07-13 2025-03-07 基因泰克公司 针对用抗fcrh5/抗cd3双特异性抗体进行的治疗的给药
WO2024033389A1 (en) 2022-08-11 2024-02-15 F. Hoffmann-La Roche Ag Bicyclic tetrahydrothiazepine derivatives
IL318163A (en) 2022-08-11 2025-03-01 Hoffmann La Roche TETRAHYDROTHIAZEPINE DERIVATIVES CYCLES
TW202417001A (zh) 2022-08-11 2024-05-01 瑞士商赫孚孟拉羅股份公司 雙環四氫吖呯衍生物
WO2024033457A1 (en) 2022-08-11 2024-02-15 F. Hoffmann-La Roche Ag Bicyclic tetrahydrothiazepine derivatives
WO2024091991A1 (en) 2022-10-25 2024-05-02 Genentech, Inc. Therapeutic and diagnostic methods for multiple myeloma
WO2025049277A1 (en) 2023-08-25 2025-03-06 Genentech, Inc. Methods and compositions for treating non-small cell lung cancer comprising an anti-tigit antagonist antibody and a pd-1 axis binding antagonist

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB827511A (en) * 1957-02-07 1960-02-03 Laporte Chemical Improvements in or relating to methyl ethyl ketone peroxides
US3003000A (en) * 1959-07-01 1961-10-03 Research Corp Organic peroxides
GB912061A (en) * 1959-09-01 1962-12-05 Laporte Chemical Improvements in or relating to the manufacture of ketone peroxides
GB1072728A (en) * 1965-11-17 1967-06-21 Wallace & Tiernan Inc Stabilised ketone peroxide compositions
US3649546A (en) * 1967-05-15 1972-03-14 Norac Co Non-hazardous ketone peroxide polymerization initiators
US3867461A (en) * 1968-02-05 1975-02-18 Argus Chem Non-hazardous ketone peroxide compositions
AT319589B (de) * 1972-07-25 1974-12-27 Chemie Linz Ag Verfahren zur Herstellung von Polypropylen
TR17756A (tr) * 1972-07-25 1976-07-01 Oesterr Stickstoffwerke Ag Mahdut molekuel agirligi dagilisina sahip polipropilenin imal edilmesine mahsus usul
DE2660923C2 (de) * 1975-06-30 1987-03-19 Argus Chemical Corp., New York, N.Y. Masse zur Herstellung von vernetztem Polyäthylen hoher Dichte und Verfahren zu dessen Herstellung
US4271279A (en) * 1975-06-30 1981-06-02 Argus Chemical Corporation Cyclic perketals and their use for cross-linking high density polyethylene
IT1104579B (it) * 1978-12-29 1985-10-21 Montedison Spa Procedimento per la preparazione di miscele ferossidiche
NL8502042A (nl) * 1985-07-16 1985-10-01 Akzo Nv Nieuwe geflegmatiseerde keton peroxide samenstellingen en hun toepassing bij de vervaardiging van gietkernen of -vormen.
US4956416A (en) * 1988-08-18 1990-09-11 Atochem North America, Inc. Amino or hydrazino peroxides, derivatives and their uses

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