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MX2022014974A - Anticuerpos anti-pd-1. - Google Patents

Anticuerpos anti-pd-1.

Info

Publication number
MX2022014974A
MX2022014974A MX2022014974A MX2022014974A MX2022014974A MX 2022014974 A MX2022014974 A MX 2022014974A MX 2022014974 A MX2022014974 A MX 2022014974A MX 2022014974 A MX2022014974 A MX 2022014974A MX 2022014974 A MX2022014974 A MX 2022014974A
Authority
MX
Mexico
Prior art keywords
antibodies
antigen
therapeutic
compositions
cell death
Prior art date
Application number
MX2022014974A
Other languages
English (en)
Inventor
Pankaj Gupta
Ivo Lorenz
Priyanka Gupta
Fei Han
Dongmei Liu
Helen Haixia Wu
David A Blair
Nicole K Garaffa
Aaron Timothy Karlak
Mouhamadou Lamine Mbow
Miguel E Moreno-Garcia
Joseph A Mozdzierz
Kerry L M Ralph
Abdulsalam Shaaban
Della M White
Guangwei Yang
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2022014974A publication Critical patent/MX2022014974A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a nuevos anticuerpos anti-PD-1 (muerte celular programada 1) y fragmentos de unión al antígeno de los mismos para métodos terapéuticos y de diagnóstico y composiciones que los utilizan.
MX2022014974A 2020-05-26 2021-05-24 Anticuerpos anti-pd-1. MX2022014974A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063029962P 2020-05-26 2020-05-26
US202063039686P 2020-06-16 2020-06-16
PCT/US2021/033823 WO2021242663A1 (en) 2020-05-26 2021-05-24 Anti-pd-1 antibodies

Publications (1)

Publication Number Publication Date
MX2022014974A true MX2022014974A (es) 2023-01-11

Family

ID=76808128

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022014974A MX2022014974A (es) 2020-05-26 2021-05-24 Anticuerpos anti-pd-1.

Country Status (30)

Country Link
US (1) US12312405B2 (es)
EP (2) EP4464383A3 (es)
JP (2) JP7512433B2 (es)
KR (1) KR102871588B1 (es)
CN (1) CN115956087B (es)
AU (1) AU2021280232B2 (es)
BR (1) BR112022023989A2 (es)
CA (1) CA3181776A1 (es)
CL (1) CL2022003304A1 (es)
CO (1) CO2022018416A2 (es)
CR (1) CR20220596A (es)
DK (1) DK4157876T3 (es)
DO (1) DOP2022000264A (es)
EC (1) ECSP22092185A (es)
ES (1) ES2994127T3 (es)
FI (1) FI4157876T3 (es)
HR (1) HRP20241488T1 (es)
HU (1) HUE069403T2 (es)
IL (1) IL298431A (es)
LT (1) LT4157876T (es)
MA (1) MA59827B1 (es)
MX (1) MX2022014974A (es)
PE (1) PE20231076A1 (es)
PH (1) PH12022553181A1 (es)
PL (1) PL4157876T3 (es)
PT (1) PT4157876T (es)
RS (1) RS66193B1 (es)
SI (1) SI4157876T1 (es)
TW (1) TWI859446B (es)
WO (1) WO2021242663A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7512433B2 (ja) 2020-05-26 2024-07-08 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗pd-1抗体
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WO2026008665A1 (en) * 2024-07-01 2026-01-08 Vib Vzw Binders of the pd-1•pd-l1 complex and their use

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CN113456582B (zh) 2020-03-30 2024-06-14 鲁南制药集团股份有限公司 重组人源化抗pd-1单克隆抗体的液体制剂
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CN113797330A (zh) 2020-06-11 2021-12-17 三生国健药业(上海)股份有限公司 一种抗pd-1单克隆抗体液体制剂
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CN111956799A (zh) 2020-09-18 2020-11-20 生物抗素公司 抗pd-1抗体和/或pd-l1抗体在制备治疗帕金森病药物中的应用

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