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MX2020010026A - Formulaciones de anticuerpos anti-pdl1. - Google Patents

Formulaciones de anticuerpos anti-pdl1.

Info

Publication number
MX2020010026A
MX2020010026A MX2020010026A MX2020010026A MX2020010026A MX 2020010026 A MX2020010026 A MX 2020010026A MX 2020010026 A MX2020010026 A MX 2020010026A MX 2020010026 A MX2020010026 A MX 2020010026A MX 2020010026 A MX2020010026 A MX 2020010026A
Authority
MX
Mexico
Prior art keywords
pdl1 antibody
antibody formulations
formulations
methods
pdl1
Prior art date
Application number
MX2020010026A
Other languages
English (en)
Inventor
Ying Yang
Sreedhara Alavattam
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51703416&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2020010026(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of MX2020010026A publication Critical patent/MX2020010026A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La invención proporciona formulaciones farmacéuticas acuosas estables que comprenden un anticuerpo anti-PDL1. La invención también proporciona métodos para preparar tales formulaciones y métodos de uso de tales formulaciones.
MX2020010026A 2013-09-27 2016-03-23 Formulaciones de anticuerpos anti-pdl1. MX2020010026A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361883953P 2013-09-27 2013-09-27

Publications (1)

Publication Number Publication Date
MX2020010026A true MX2020010026A (es) 2020-10-14

Family

ID=51703416

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2016003939A MX375378B (es) 2013-09-27 2014-09-26 Formulaciones de anticuerpos anti-pdl1.
MX2020010026A MX2020010026A (es) 2013-09-27 2016-03-23 Formulaciones de anticuerpos anti-pdl1.
MX2022014781A MX2022014781A (es) 2013-09-27 2016-03-23 Formulaciones de anticuerpos anti-pdl1.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2016003939A MX375378B (es) 2013-09-27 2014-09-26 Formulaciones de anticuerpos anti-pdl1.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022014781A MX2022014781A (es) 2013-09-27 2016-03-23 Formulaciones de anticuerpos anti-pdl1.

Country Status (32)

Country Link
US (4) US10875922B2 (es)
EP (3) EP3626742A1 (es)
JP (3) JP6942465B2 (es)
KR (1) KR102331663B1 (es)
CN (1) CN105793288B (es)
AR (2) AR097791A1 (es)
AU (3) AU2014324703C1 (es)
BR (1) BR112016006397B1 (es)
CA (1) CA2925310C (es)
CL (1) CL2016000680A1 (es)
CR (1) CR20160141A (es)
DK (1) DK3049441T3 (es)
EA (2) EA201991715A1 (es)
ES (1) ES2768614T3 (es)
HR (1) HRP20200102T1 (es)
HU (1) HUE047194T2 (es)
IL (3) IL244712B (es)
LT (1) LT3049441T (es)
MA (1) MA38960A1 (es)
MX (3) MX375378B (es)
MY (1) MY175472A (es)
NZ (1) NZ719036A (es)
PE (1) PE20160541A1 (es)
PH (2) PH12016500566A1 (es)
PL (1) PL3049441T3 (es)
PT (1) PT3049441T (es)
RS (1) RS59880B1 (es)
SG (2) SG10201708542RA (es)
SI (1) SI3049441T1 (es)
TW (2) TWI714022B (es)
UA (1) UA122478C2 (es)
WO (1) WO2015048520A1 (es)

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