MX2014001377A - Metodo para detectar cancer pancreatico. - Google Patents
Metodo para detectar cancer pancreatico.Info
- Publication number
- MX2014001377A MX2014001377A MX2014001377A MX2014001377A MX2014001377A MX 2014001377 A MX2014001377 A MX 2014001377A MX 2014001377 A MX2014001377 A MX 2014001377A MX 2014001377 A MX2014001377 A MX 2014001377A MX 2014001377 A MX2014001377 A MX 2014001377A
- Authority
- MX
- Mexico
- Prior art keywords
- pancreatic cancer
- detecting pancreatic
- antibody
- caprin
- protein
- Prior art date
Links
- 206010061902 Pancreatic neoplasm Diseases 0.000 title abstract 4
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 title abstract 4
- 201000002528 pancreatic cancer Diseases 0.000 title abstract 4
- 208000008443 pancreatic carcinoma Diseases 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 102100029949 Caprin-1 Human genes 0.000 abstract 2
- 101710072528 Caprin-1 Proteins 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000000439 tumor marker Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un método para detectar cáncer pancreático que utiliza un nuevo marcador tumoral. Más específicamente, la presente invención proporciona lo siguiente: un método para detectar cáncer pancreático que incluye ensayar la existencia o cantidad de un polipéptido reactivo que se une a un anticuerpo contra la proteína CAPRIN-1 a través de una reacción antígeno-anticuerpo en una muestra aislada a partir de un sujeto de prueba; un reactivo para la detección de cáncer pancreático que incluye un anticuerpo contra la proteína CAPRIN-1 o un fragmento de la misma, y un polinucleótido que codifica para un anticuerpo de este tipo, y un kit.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011171364 | 2011-08-04 | ||
PCT/JP2012/069824 WO2013018885A1 (ja) | 2011-08-04 | 2012-08-03 | 膵臓癌の検出方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014001377A true MX2014001377A (es) | 2014-03-21 |
MX349907B MX349907B (es) | 2017-08-18 |
Family
ID=47629399
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014001377A MX349907B (es) | 2011-08-04 | 2012-08-03 | Metodo para detectar cancer pancreatico. |
Country Status (16)
Country | Link |
---|---|
US (1) | US9796775B2 (es) |
EP (1) | EP2741085B1 (es) |
JP (1) | JP6094220B2 (es) |
KR (1) | KR101984554B1 (es) |
CN (1) | CN103718045B (es) |
AU (1) | AU2012290948B2 (es) |
BR (1) | BR112014002616B1 (es) |
CA (1) | CA2844033C (es) |
DK (1) | DK2741085T3 (es) |
ES (1) | ES2629061T3 (es) |
HU (1) | HUE033628T2 (es) |
MX (1) | MX349907B (es) |
PL (1) | PL2741085T3 (es) |
PT (1) | PT2741085T (es) |
RU (1) | RU2624040C2 (es) |
WO (1) | WO2013018885A1 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101638490B1 (ko) | 2008-08-05 | 2016-07-11 | 도레이 카부시키가이샤 | 암의 치료 및 예방용 의약 조성물 |
DK2325648T3 (da) | 2008-08-05 | 2014-07-28 | Toray Industries | Fremgangsmåde til detektering af cancer |
CN102821788B (zh) | 2010-02-04 | 2016-11-16 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
EP2532364B1 (en) | 2010-02-04 | 2016-05-04 | Toray Industries, Inc. | Pharmaceutical composition comprising anti caprin-1 antibodies for treating and/or preventing cancer |
BR112012018951C8 (pt) | 2010-02-04 | 2020-06-23 | Toray Industries | anticorpo monoclonal, composição farmacêutica, combinação farmacêutica, uso de um anticorpo, uso de uma composição farmacêutica e uso de uma combinação farmacêutica |
MX340017B (es) | 2010-02-04 | 2016-06-22 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
RU2603742C2 (ru) | 2010-02-04 | 2016-11-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
ES2691738T3 (es) | 2010-02-04 | 2018-11-28 | Toray Industries, Inc. | Agente farmacéutico para el tratamiento y/o la prevención de cáncer |
CA2844030C (en) | 2011-08-04 | 2019-09-03 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
MX351682B (es) | 2011-08-04 | 2017-10-25 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
BR112014002621B1 (pt) | 2011-08-04 | 2022-09-20 | Toray Industries, Inc | Anticorpo, ou seu fragmento, composição farmacêutica, uso de um anticorpo e uso de uma composição farmacêutica |
BR112014002619A2 (pt) | 2011-08-04 | 2018-10-09 | Toray Industries, Inc | composição farmacêutica e método de tratamento e/ou prevenção de câncer pancreático e combinação farmacêutica |
JP6065590B2 (ja) | 2011-08-04 | 2017-01-25 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
WO2013018889A1 (ja) | 2011-08-04 | 2013-02-07 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
EP2741085B1 (en) | 2011-08-04 | 2017-04-05 | Toray Industries, Inc. | Method for detecting pancreatic cancer |
CA2864864C (en) | 2012-02-21 | 2020-05-12 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
DK2818483T3 (en) | 2012-02-21 | 2017-10-23 | Toray Industries | Medical composition for the treatment and / or prevention of cancer |
HUE046788T2 (hu) * | 2012-02-21 | 2020-03-30 | Toray Industries | Gyógyászati készítmény rák kezelésére és/vagy megelõzésére |
KR102009236B1 (ko) | 2012-02-21 | 2019-08-09 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
WO2013147176A1 (ja) * | 2012-03-30 | 2013-10-03 | 東レ株式会社 | 胆嚢癌の治療及び/又は予防用医薬組成物 |
ES2656620T3 (es) * | 2012-03-30 | 2018-02-27 | Toray Industries, Inc. | Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado |
EP2876447B1 (en) | 2012-07-19 | 2019-11-20 | Toray Industries, Inc. | Method for detecting cancer |
CN104471403B (zh) | 2012-07-19 | 2017-03-01 | 东丽株式会社 | 癌的检测方法 |
PT3031826T (pt) | 2013-08-09 | 2019-01-18 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção do cancro |
RU2612082C1 (ru) * | 2015-10-14 | 2017-03-02 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ прогнозирования направленности патологического процесса при раке головки поджелудочной железы |
JP7011764B2 (ja) | 2016-07-07 | 2022-01-27 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 抗体アジュバント複合体 |
EP3937984A1 (en) | 2019-03-15 | 2022-01-19 | Bolt Biotherapeutics, Inc. | Immunoconjugates targeting her2 |
RU2712921C1 (ru) * | 2019-08-12 | 2020-02-03 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ индивидуального прогнозирования сроков прогрессирования плоскоклеточного рака пищевода II-III стадии после хирургического лечения |
JPWO2022138460A1 (es) * | 2020-12-24 | 2022-06-30 | ||
CN119306830B (zh) * | 2023-07-11 | 2025-06-20 | 东莞市朋志生物科技有限公司 | 抗皮质醇抗体、检测皮质醇的试剂和试剂盒 |
Family Cites Families (81)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9508959A (pt) | 1994-09-19 | 1997-12-30 | Ricardo J Moro | "Detecção e tratamento de cancer" |
US5698396A (en) | 1995-06-07 | 1997-12-16 | Ludwig Institute For Cancer Research | Method for identifying auto-immunoreactive substances from a subject |
US20030118599A1 (en) | 1999-04-02 | 2003-06-26 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
RU2234942C2 (ru) | 1998-07-14 | 2004-08-27 | Корикса Корпорейшн | Выделенный опухолевый полипептид предстательной железы и кодирующий его полинуклеотид |
EP1097208A2 (en) | 1998-07-14 | 2001-05-09 | Corixa Corporation | Compositions and methods for therapy and diagnosis of prostate cancer |
GB9815909D0 (en) | 1998-07-21 | 1998-09-16 | Btg Int Ltd | Antibody preparation |
US6969518B2 (en) | 1998-12-28 | 2005-11-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
WO2000052204A2 (en) | 1999-02-22 | 2000-09-08 | Orntoft Torben F | Gene expression in bladder tumors |
US6444425B1 (en) | 1999-04-02 | 2002-09-03 | Corixa Corporation | Compounds for therapy and diagnosis of lung cancer and methods for their use |
JP2002540790A (ja) | 1999-04-02 | 2002-12-03 | コリクサ コーポレイション | 肺癌の治療および診断のための化合物ならびにその使用のための方法 |
US6949245B1 (en) | 1999-06-25 | 2005-09-27 | Genentech, Inc. | Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies |
AU1438001A (en) | 1999-10-29 | 2001-05-14 | Human Genome Sciences, Inc. | 27 human secreted proteins |
US20020006404A1 (en) | 1999-11-08 | 2002-01-17 | Idec Pharmaceuticals Corporation | Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications |
AU2001261007A1 (en) | 2000-03-29 | 2001-10-08 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US7919467B2 (en) | 2000-12-04 | 2011-04-05 | Immunotope, Inc. | Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
US7408041B2 (en) | 2000-12-08 | 2008-08-05 | Alexion Pharmaceuticals, Inc. | Polypeptides and antibodies derived from chronic lymphocytic leukemia cells and uses thereof |
US20040029114A1 (en) | 2001-01-24 | 2004-02-12 | Eos Technology, Inc. | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer |
RU2306952C2 (ru) | 2001-01-31 | 2007-09-27 | Байоджен Айдек Инк. | Лечение в-клеточных злокачественных опухолей с использованием комбинации применений, связанных с антителами, уменьшающими количество b-клеток, и с иммуномодулирующими антителами |
AU2002311787A1 (en) | 2001-03-28 | 2002-10-15 | Zycos Inc. | Translational profiling |
WO2002083070A2 (en) | 2001-04-10 | 2002-10-24 | Corixa Corporation | Compounds for immunotherapy and diagnosis of colon cancer and methods for their use |
WO2002092001A2 (en) | 2001-05-11 | 2002-11-21 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US20030190640A1 (en) | 2001-05-31 | 2003-10-09 | Mary Faris | Genes expressed in prostate cancer |
RU2319709C2 (ru) | 2001-07-17 | 2008-03-20 | Рисерч Дивелопмент Фаундейшн | Терапевтические агенты, содержащие проапоптозные белки |
AU2002327310B2 (en) | 2001-07-17 | 2006-09-28 | Research Development Foundation | Therapeutic agents comprising pro-apoptotic proteins |
US20040142325A1 (en) | 2001-09-14 | 2004-07-22 | Liat Mintz | Methods and systems for annotating biomolecular sequences |
JP2005535290A (ja) | 2002-02-22 | 2005-11-24 | ジェネンテック・インコーポレーテッド | 免疫関連疾患の治療のための組成物と方法 |
US20050003390A1 (en) | 2002-05-17 | 2005-01-06 | Axenovich Sergey A. | Targets for controlling cellular growth and for diagnostic methods |
US20040126379A1 (en) | 2002-08-21 | 2004-07-01 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents |
CA2504144A1 (en) | 2002-11-26 | 2004-06-10 | Genentech, Inc. | Compositions and methods for the diagnosis of immune related diseases using pro7 |
WO2004076682A2 (en) | 2003-02-26 | 2004-09-10 | Surromed, Inc. | Targets for controlling cellular growth and for diagnostic methods |
WO2004097051A2 (en) | 2003-04-29 | 2004-11-11 | Wyeth | Methods for diagnosing aml and mds differential gene expression |
US20050009067A1 (en) * | 2003-05-19 | 2005-01-13 | Craig Logsdon | Expression profile of pancreatic cancer |
EP2003196A3 (en) | 2003-06-09 | 2009-01-07 | The Regents of the University of Michigan | Compositions and methods for treating and diagnosing cancer |
WO2005007830A2 (en) | 2003-07-14 | 2005-01-27 | Mayo Foundation For Medical Education And Research | Methods and compositions for diagnosis, staging and prognosis of prostate cancer |
US20050032113A1 (en) | 2003-07-17 | 2005-02-10 | Mitsubishi Pharma Corporation | Membrane protein library for proteome analysis and method for preparing same |
WO2005116076A2 (en) | 2004-01-26 | 2005-12-08 | Debiovision Inc. | Neoplasm-specific polypeptides and their uses |
JP4734319B2 (ja) | 2004-03-19 | 2011-07-27 | イムクローン・リミテッド・ライアビリティ・カンパニー | ヒト抗上皮成長因子受容体抗体 |
WO2005100998A2 (en) * | 2004-04-16 | 2005-10-27 | Europroteome Ag | Membrane markers for use in cancer diagnosis and therapy |
WO2006002378A2 (en) | 2004-06-23 | 2006-01-05 | Avalon Pharmaceuticals | Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods |
CN101102776B (zh) | 2005-01-19 | 2011-08-24 | 善利亚新药工业股份有限公司 | 抗肿瘤药 |
CN101141981A (zh) | 2005-01-21 | 2008-03-12 | 健泰科生物技术公司 | Her抗体的固定剂量给药 |
AU2006214105A1 (en) | 2005-02-18 | 2006-08-24 | Children's Medical Center Corporation | Cyr61 as a biomarker for diagnosis and prognosis of cancers of epithelial origin |
EP1869462B1 (en) | 2005-03-11 | 2013-05-08 | Ciphergen Biosystems, Inc. | Biomarkers for ovarian cancer and endometrial cancer: hepcidin |
JP2006316040A (ja) | 2005-05-13 | 2006-11-24 | Genentech Inc | Herceptin(登録商標)補助療法 |
US8014957B2 (en) | 2005-12-15 | 2011-09-06 | Fred Hutchinson Cancer Research Center | Genes associated with progression and response in chronic myeloid leukemia and uses thereof |
EP2591794A1 (en) * | 2006-01-05 | 2013-05-15 | The Ohio State University Research Foundation | MicroRNA expressions abnormalities in pancreatic endocrine and acinar tumors |
WO2007095186A2 (en) * | 2006-02-14 | 2007-08-23 | Dana-Farber Cancer Institute, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
US20100015724A1 (en) | 2006-08-17 | 2010-01-21 | Peter Hornbeck | Lysine acetylation sites |
US20080107668A1 (en) * | 2006-08-30 | 2008-05-08 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
WO2008031041A2 (en) | 2006-09-07 | 2008-03-13 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Melanoma gene signature |
WO2008059252A2 (en) | 2006-11-15 | 2008-05-22 | Oxford Biomedica (Uk) Limited | Methods and composition fro t cell receptors which recognize 5t4 antigen |
US9249409B2 (en) | 2007-10-25 | 2016-02-02 | Toray Industries, Inc. | Method for detection of cancer |
JP5663834B2 (ja) | 2008-03-14 | 2015-02-04 | 東ソー株式会社 | 遺伝子組換え抗体の製造方法 |
IL274393B (en) | 2008-03-18 | 2022-09-01 | Genentech Inc | Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use |
DK2325648T3 (da) * | 2008-08-05 | 2014-07-28 | Toray Industries | Fremgangsmåde til detektering af cancer |
KR101638490B1 (ko) | 2008-08-05 | 2016-07-11 | 도레이 카부시키가이샤 | 암의 치료 및 예방용 의약 조성물 |
DK2837383T3 (en) | 2008-08-05 | 2017-03-20 | Toray Industries | Immunity Inducing Agent |
CN102597001B (zh) | 2009-08-19 | 2014-07-30 | 默克专利有限公司 | 在ffpe材料中用于检测整联蛋白复合体的抗体 |
CA2773240C (en) | 2009-09-22 | 2015-11-10 | Volker Sandig | Process for producing molecules containing specialized glycan structures |
RU2603742C2 (ru) | 2010-02-04 | 2016-11-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
BR112012018951C8 (pt) | 2010-02-04 | 2020-06-23 | Toray Industries | anticorpo monoclonal, composição farmacêutica, combinação farmacêutica, uso de um anticorpo, uso de uma composição farmacêutica e uso de uma combinação farmacêutica |
ES2691738T3 (es) | 2010-02-04 | 2018-11-28 | Toray Industries, Inc. | Agente farmacéutico para el tratamiento y/o la prevención de cáncer |
EP2532364B1 (en) | 2010-02-04 | 2016-05-04 | Toray Industries, Inc. | Pharmaceutical composition comprising anti caprin-1 antibodies for treating and/or preventing cancer |
MX340017B (es) | 2010-02-04 | 2016-06-22 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
CN102821788B (zh) | 2010-02-04 | 2016-11-16 | 东丽株式会社 | 癌的治疗和/或预防用药物组合物 |
KR101271964B1 (ko) | 2010-07-08 | 2013-06-07 | 강원대학교산학협력단 | 담낭암 치료용 약제학적 조성물 및 이를 이용한 담낭암의 성장, 전이 억제 및 치료 방법 |
WO2012013609A1 (en) | 2010-07-26 | 2012-02-02 | Bioréalités S.A.S. | Methods and compositions for liver cancer therapy |
BR112014002621B1 (pt) * | 2011-08-04 | 2022-09-20 | Toray Industries, Inc | Anticorpo, ou seu fragmento, composição farmacêutica, uso de um anticorpo e uso de uma composição farmacêutica |
EP2741085B1 (en) | 2011-08-04 | 2017-04-05 | Toray Industries, Inc. | Method for detecting pancreatic cancer |
JP6065590B2 (ja) | 2011-08-04 | 2017-01-25 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
CA2844030C (en) * | 2011-08-04 | 2019-09-03 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
WO2013018889A1 (ja) * | 2011-08-04 | 2013-02-07 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
BR112014002619A2 (pt) | 2011-08-04 | 2018-10-09 | Toray Industries, Inc | composição farmacêutica e método de tratamento e/ou prevenção de câncer pancreático e combinação farmacêutica |
MX351682B (es) | 2011-08-04 | 2017-10-25 | Toray Industries | Composicion farmaceutica para el tratamiento y/o prevencion del cancer. |
CA2864864C (en) * | 2012-02-21 | 2020-05-12 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
KR102009236B1 (ko) * | 2012-02-21 | 2019-08-09 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
DK2818483T3 (en) * | 2012-02-21 | 2017-10-23 | Toray Industries | Medical composition for the treatment and / or prevention of cancer |
HUE046788T2 (hu) * | 2012-02-21 | 2020-03-30 | Toray Industries | Gyógyászati készítmény rák kezelésére és/vagy megelõzésére |
WO2013147176A1 (ja) | 2012-03-30 | 2013-10-03 | 東レ株式会社 | 胆嚢癌の治療及び/又は予防用医薬組成物 |
ES2656620T3 (es) | 2012-03-30 | 2018-02-27 | Toray Industries, Inc. | Composición farmacéutica para el tratamiento y/o la prevención del cáncer de hígado |
PT3031826T (pt) | 2013-08-09 | 2019-01-18 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção do cancro |
-
2012
- 2012-08-03 EP EP12819473.5A patent/EP2741085B1/en active Active
- 2012-08-03 ES ES12819473.5T patent/ES2629061T3/es active Active
- 2012-08-03 CN CN201280038482.9A patent/CN103718045B/zh active Active
- 2012-08-03 MX MX2014001377A patent/MX349907B/es active IP Right Grant
- 2012-08-03 CA CA2844033A patent/CA2844033C/en active Active
- 2012-08-03 RU RU2014108048A patent/RU2624040C2/ru active
- 2012-08-03 HU HUE12819473A patent/HUE033628T2/en unknown
- 2012-08-03 KR KR1020147005905A patent/KR101984554B1/ko active Active
- 2012-08-03 PL PL12819473T patent/PL2741085T3/pl unknown
- 2012-08-03 JP JP2012543815A patent/JP6094220B2/ja active Active
- 2012-08-03 DK DK12819473.5T patent/DK2741085T3/en active
- 2012-08-03 WO PCT/JP2012/069824 patent/WO2013018885A1/ja active Application Filing
- 2012-08-03 US US14/236,807 patent/US9796775B2/en active Active
- 2012-08-03 AU AU2012290948A patent/AU2012290948B2/en active Active
- 2012-08-03 PT PT128194735T patent/PT2741085T/pt unknown
- 2012-08-03 BR BR112014002616-5A patent/BR112014002616B1/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
MX349907B (es) | 2017-08-18 |
CN103718045B (zh) | 2016-08-17 |
AU2012290948B2 (en) | 2017-05-25 |
EP2741085A4 (en) | 2015-03-04 |
CA2844033A1 (en) | 2013-02-07 |
CN103718045A (zh) | 2014-04-09 |
BR112014002616A2 (pt) | 2019-03-19 |
BR112014002616B1 (pt) | 2022-01-18 |
EP2741085B1 (en) | 2017-04-05 |
HUE033628T2 (en) | 2017-12-28 |
DK2741085T3 (en) | 2017-06-19 |
PL2741085T3 (pl) | 2017-09-29 |
US9796775B2 (en) | 2017-10-24 |
US20140179558A1 (en) | 2014-06-26 |
CA2844033C (en) | 2021-07-27 |
EP2741085A1 (en) | 2014-06-11 |
PT2741085T (pt) | 2017-06-30 |
AU2012290948A1 (en) | 2014-03-20 |
WO2013018885A1 (ja) | 2013-02-07 |
JPWO2013018885A1 (ja) | 2015-03-05 |
ES2629061T3 (es) | 2017-08-07 |
JP6094220B2 (ja) | 2017-03-15 |
RU2624040C2 (ru) | 2017-06-30 |
KR20140048318A (ko) | 2014-04-23 |
RU2014108048A (ru) | 2015-09-10 |
KR101984554B1 (ko) | 2019-05-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX349907B (es) | Metodo para detectar cancer pancreatico. | |
MX2015008045A (es) | Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano. | |
NZ593514A (en) | p-mTOR and p-AKT as Ratio Based Biomarkers for the Prognosis and/or Diagnosis of Cancer | |
MX337991B (es) | Metodo para detectar cancer. | |
MX2015006680A (es) | Composiciones y metodos para diagnosticar tumores de tiroides. | |
BR112016004437A2 (pt) | métodos de imunoteste e de seleção de linhagem de células, anticorpos e kit | |
MX2015000684A (es) | Metodo para detectar cancer. | |
TW200741203A (en) | Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody | |
BR112012030788B8 (pt) | Anticorpo monoclonal, linhagem celular de hibridoma, e métodos para identificar a presença e para determinação quantitativa de uma enzima aad-12 | |
WO2010096674A3 (en) | A+ biomarker assays | |
MX344053B (es) | Metodos para determinar isotipos de anticuerpos anti-farmacos. | |
WO2012075506A3 (en) | Methods for predicting and treating infection-induced illnesses and predicting the severity of infection-induced illnesses | |
MX357292B (es) | Método para detectar cáncer. | |
WO2008012362A3 (en) | New protein isoforms and uses thereof | |
MX2008000282A (es) | Anticuerpos monoclonales, lineas celulares de hibridomas, metodos y kits para la deteccion de fitasa. | |
WO2012155134A3 (en) | Assay reagents for a neurogranin diagnostic kit | |
RU2015104737A (ru) | Способ обнаружения мультиспецифического связывающего агента | |
EA201370030A1 (ru) | Бифункциональный количественный анализ in vitro связывания мишени для обнаружения нейтрализующих антител к антителам-мишеням | |
MX2015004419A (es) | Deteccion de analito y determinacion de concentracion de analito mediante uso de perlas magnetizables. | |
WO2006034278A3 (en) | Methods and compositions for detecting cancer using components of the u2 spliceosomal particle | |
GB201119585D0 (en) | Assay | |
WO2011137389A3 (en) | Compositions and methods for reliably detecting and/or measuring the amount of a modified target protein in a sample | |
WO2007105110A3 (en) | Ercc1 expression in predicting response for cancer chemotherapy | |
CA3080263A1 (en) | Method for diagnosing cancer from blood | |
GB201010405D0 (en) | Assay |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |