MX337991B - Metodo para detectar cancer. - Google Patents
Metodo para detectar cancer.Info
- Publication number
- MX337991B MX337991B MX2013011525A MX2013011525A MX337991B MX 337991 B MX337991 B MX 337991B MX 2013011525 A MX2013011525 A MX 2013011525A MX 2013011525 A MX2013011525 A MX 2013011525A MX 337991 B MX337991 B MX 337991B
- Authority
- MX
- Mexico
- Prior art keywords
- protein
- cancer detection
- caprin
- fragment
- detection method
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 3
- 102100029949 Caprin-1 Human genes 0.000 abstract 4
- 101710072528 Caprin-1 Proteins 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 230000009257 reactivity Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La presente invención se refiere a un método in vitro para detectar cáncer, caracterizado porque comprende medir la expresión de un polipéptido que tiene una reactividad de unión por medio de una reacción antígeno-anticuerpo a un anticuerpo contra una proteína CAPRIN-1que tiene cualquiera de las secuencias de aminoácidos que se muestran en las SEC ID. NOS: 2 a 30 con numeración par en el listado de secuencias, sobre una superficie de célula cancerosa en una muestra separada de un organismo vivo. El método in vitro porque comprende detectar además el progreso de cáncer un base a un indicador de que la extensión del cáncer ha avanzado cuando el nivel de expresión del polipéptido es mayor que la de un control.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008202320 | 2008-08-05 | ||
PCT/JP2009/063883 WO2010016527A1 (ja) | 2008-08-05 | 2009-08-05 | 癌の検出方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX337991B true MX337991B (es) | 2016-03-30 |
Family
ID=41663744
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011001445A MX2011001445A (es) | 2008-08-05 | 2009-08-05 | Metodo para detectar cancer. |
MX2013011525A MX337991B (es) | 2008-08-05 | 2009-08-05 | Metodo para detectar cancer. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011001445A MX2011001445A (es) | 2008-08-05 | 2009-08-05 | Metodo para detectar cancer. |
Country Status (16)
Country | Link |
---|---|
US (1) | US11137401B2 (es) |
EP (2) | EP2733492B1 (es) |
JP (2) | JP5644110B2 (es) |
KR (2) | KR20160039295A (es) |
CN (1) | CN102171570B (es) |
AU (2) | AU2009278387B2 (es) |
BR (1) | BRPI0911925B8 (es) |
CA (1) | CA2732980C (es) |
DK (2) | DK2325648T3 (es) |
ES (2) | ES2570731T3 (es) |
HU (1) | HUE027332T2 (es) |
MX (2) | MX2011001445A (es) |
PL (2) | PL2733492T3 (es) |
PT (1) | PT2325648E (es) |
RU (2) | RU2519089C2 (es) |
WO (1) | WO2010016527A1 (es) |
Families Citing this family (31)
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MX2011001445A (es) | 2008-08-05 | 2011-04-05 | Toray Industries | Metodo para detectar cancer. |
JP5691172B2 (ja) | 2008-08-05 | 2015-04-01 | 東レ株式会社 | 癌の治療及び予防用医薬組成物 |
CN102844048A (zh) * | 2010-02-04 | 2012-12-26 | 东丽株式会社 | 用于癌的治疗和/或预防的药物 |
JP5742713B2 (ja) | 2010-02-04 | 2015-07-01 | 東レ株式会社 | 癌の治療及び/又は予防用医薬組成物 |
CA2788547C (en) | 2010-02-04 | 2018-06-05 | Toray Industries, Inc. | Pharmaceutical composition for treating and/or preventing cancer |
RU2607366C2 (ru) | 2010-02-04 | 2017-01-10 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики рака |
ES2540858T3 (es) * | 2010-02-04 | 2015-07-14 | Toray Industries, Inc. | Composición farmacéutica para el tratamiento y/o la prevención de cáncer |
ES2583777T3 (es) | 2010-02-04 | 2016-09-22 | Toray Industries, Inc. | Composición farmacéutica que comprende anticuerpos anti CAPRIN-1 para el tratamiento y/o la prevención del cáncer |
RU2611197C2 (ru) * | 2011-08-04 | 2017-02-21 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли |
RU2595400C2 (ru) * | 2011-08-04 | 2016-08-27 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и/или профилактики злокачественной опухоли |
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WO2014014086A1 (ja) | 2012-07-19 | 2014-01-23 | 東レ株式会社 | 癌の検出方法 |
PT3031826T (pt) | 2013-08-09 | 2019-01-18 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção do cancro |
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