ATE535546T1 - Humane monoklonale antikörper, die spezifisch an ifg-ii binden - Google Patents
Humane monoklonale antikörper, die spezifisch an ifg-ii bindenInfo
- Publication number
- ATE535546T1 ATE535546T1 AT06789775T AT06789775T ATE535546T1 AT E535546 T1 ATE535546 T1 AT E535546T1 AT 06789775 T AT06789775 T AT 06789775T AT 06789775 T AT06789775 T AT 06789775T AT E535546 T1 ATE535546 T1 AT E535546T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- disclosed
- nucleic acids
- igf
- ifg
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 102000048143 Insulin-Like Growth Factor II Human genes 0.000 abstract 2
- 108090001117 Insulin-Like Growth Factor II Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 238000010494 dissociation reaction Methods 0.000 abstract 2
- 230000005593 dissociations Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101001076292 Homo sapiens Insulin-like growth factor II Proteins 0.000 abstract 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 1
- 102000004218 Insulin-Like Growth Factor I Human genes 0.000 abstract 1
- 102000004584 Somatomedin Receptors Human genes 0.000 abstract 1
- 108010017622 Somatomedin Receptors Proteins 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 102000057877 human IGF2 Human genes 0.000 abstract 1
- 230000026731 phosphorylation Effects 0.000 abstract 1
- 238000006366 phosphorylation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70922605P | 2005-08-17 | 2005-08-17 | |
| US79881706P | 2006-05-08 | 2006-05-08 | |
| PCT/US2006/031814 WO2007022172A1 (en) | 2005-08-17 | 2006-08-15 | Human monoclonal antibodies that specifically bind igf-ii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE535546T1 true ATE535546T1 (de) | 2011-12-15 |
Family
ID=37564252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06789775T ATE535546T1 (de) | 2005-08-17 | 2006-08-15 | Humane monoklonale antikörper, die spezifisch an ifg-ii binden |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8105598B2 (de) |
| EP (1) | EP1924604B1 (de) |
| JP (1) | JP5149800B2 (de) |
| AT (1) | ATE535546T1 (de) |
| AU (1) | AU2006279633B2 (de) |
| CA (1) | CA2618920C (de) |
| WO (1) | WO2007022172A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG179291A1 (en) | 2003-06-18 | 2012-04-27 | Genelux Corp | Modified recombinant vaccinia viruses and other microorganisms, uses thereof |
| MX2008007688A (es) | 2005-12-13 | 2008-09-26 | Astrazeneca Ab | Proteinas de enlace especificas de factores de crecimiento tipo insulina y usos de las mismas. |
| EP2296703A4 (de) * | 2008-05-09 | 2012-09-05 | Dyax Corp | Igf-ii/gf-iie-bindungsproteine |
| US20110262446A1 (en) * | 2008-10-14 | 2011-10-27 | Dyax Corp. | Use of igf-ii/igf-iie binding proteins for the treatment and prevention of systemic sclerosis associated pulmonary fibrosis |
| CZ2008697A3 (cs) * | 2008-11-03 | 2010-04-28 | Univerzita Karlova v Praze, 1. Lékarská fakulta | Kombinace monoklonálních protilátek nebo jejich Fab fragmentu pro použití jako lécivo a farmaceutický prípravek tyto protilátky nebo jejich Fab fragmenty obsahující |
| US9150644B2 (en) | 2011-04-12 | 2015-10-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Human monoclonal antibodies that bind insulin-like growth factor (IGF) I and II |
| US9127056B2 (en) | 2011-10-17 | 2015-09-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Monospecific and bispecific human monoclonal antibodies targeting insulin-like growth factor II (IGF-II) |
| WO2013119419A1 (en) | 2012-02-08 | 2013-08-15 | North Carolina State University | Treatment of allergic diseases with recombinant antibodies |
| CN106519024A (zh) * | 2015-09-15 | 2017-03-22 | 三生国健药业（上海）股份有限公司 | 一种用于去除单克隆抗体中异构体的复性液及复性方法 |
| CA3041717A1 (en) | 2016-11-09 | 2018-05-17 | North Carolina State University | Treatment of allergic diseases with chimeric protein |
| WO2019183437A1 (en) | 2018-03-23 | 2019-09-26 | North Carolina State University | Methods and compositions for antibody to high affinity receptor for ige |
-
2006
- 2006-08-15 WO PCT/US2006/031814 patent/WO2007022172A1/en active Application Filing
- 2006-08-15 JP JP2008527056A patent/JP5149800B2/ja not_active Expired - Fee Related
- 2006-08-15 AU AU2006279633A patent/AU2006279633B2/en not_active Ceased
- 2006-08-15 EP EP06789775A patent/EP1924604B1/de not_active Not-in-force
- 2006-08-15 CA CA2618920A patent/CA2618920C/en active Active
- 2006-08-15 AT AT06789775T patent/ATE535546T1/de active
-
2010
- 2010-09-23 US US12/889,345 patent/US8105598B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007022172A1 (en) | 2007-02-22 |
| AU2006279633A1 (en) | 2007-02-22 |
| CA2618920C (en) | 2015-03-24 |
| JP2009507471A (ja) | 2009-02-26 |
| US8105598B2 (en) | 2012-01-31 |
| JP5149800B2 (ja) | 2013-02-20 |
| EP1924604A1 (de) | 2008-05-28 |
| AU2006279633B2 (en) | 2011-03-03 |
| EP1924604B1 (de) | 2011-11-30 |
| CA2618920A1 (en) | 2007-02-22 |
| US20110008358A1 (en) | 2011-01-13 |
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