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MX2009006706A - Compuestos heterociclicos biciclicos como inhibidores del receptor del factor de crecimiento de fibroblastos. - Google Patents

Compuestos heterociclicos biciclicos como inhibidores del receptor del factor de crecimiento de fibroblastos.

Info

Publication number
MX2009006706A
MX2009006706A MX2009006706A MX2009006706A MX2009006706A MX 2009006706 A MX2009006706 A MX 2009006706A MX 2009006706 A MX2009006706 A MX 2009006706A MX 2009006706 A MX2009006706 A MX 2009006706A MX 2009006706 A MX2009006706 A MX 2009006706A
Authority
MX
Mexico
Prior art keywords
bicyclic heterocyclic
heterocyclic compounds
fgfr inhibitors
compounds
fgfr
Prior art date
Application number
MX2009006706A
Other languages
English (en)
Inventor
Miles Stuart Congreve
Valerio Berdini
Adrian Liam Gill
Gilbert Ebai Bensong
Maria Grazia Carr
Andrew Madin
Christopher William Murray
Rajdeep Kaur Nijjar
Michael Alistair O'brien
Andrew Pike
Gordon Saxty
Emma Vickerstaffe
Richard David Taylor
Owen Callaghan
Charlotte Mary Griffiths-Jones
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0625826A external-priority patent/GB0625826D0/en
Priority claimed from GB0720000A external-priority patent/GB0720000D0/en
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of MX2009006706A publication Critical patent/MX2009006706A/es

Links

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Psychiatry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)

Abstract

La invención se refiere a nuevos compuestos derivados heterocíclicos bicíclicos, a composiciones farmacéuticas que comprenden los compuestos y al uso de los compuestos en el tratamiento de enfermedades, por ejemplo, el cáncer.
MX2009006706A 2006-12-22 2007-12-21 Compuestos heterociclicos biciclicos como inhibidores del receptor del factor de crecimiento de fibroblastos. MX2009006706A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US87154306P 2006-12-22 2006-12-22
GB0625826A GB0625826D0 (en) 2006-12-22 2006-12-22 New compounds
US97958707P 2007-10-12 2007-10-12
GB0720000A GB0720000D0 (en) 2007-10-12 2007-10-12 New compounds
US98103907P 2007-10-18 2007-10-18
PCT/GB2007/004934 WO2008078091A1 (en) 2006-12-22 2007-12-21 Bicyclic heterocyclic compounds as fgfr inhibitors

Publications (1)

Publication Number Publication Date
MX2009006706A true MX2009006706A (es) 2009-07-02

Family

ID=39260738

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006706A MX2009006706A (es) 2006-12-22 2007-12-21 Compuestos heterociclicos biciclicos como inhibidores del receptor del factor de crecimiento de fibroblastos.

Country Status (11)

Country Link
US (1) US8895745B2 (es)
EP (1) EP2114941B1 (es)
JP (1) JP5442448B2 (es)
CN (1) CN101679408B (es)
AR (1) AR064491A1 (es)
AU (1) AU2007337886C1 (es)
CA (1) CA2672172C (es)
HR (1) HRP20150642T1 (es)
MX (1) MX2009006706A (es)
NO (1) NO343370B1 (es)
WO (1) WO2008078091A1 (es)

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AU2007337886B2 (en) 2014-01-30
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JP5442448B2 (ja) 2014-03-12
AR064491A1 (es) 2009-04-08
WO2008078091A1 (en) 2008-07-03
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