[go: up one dir, main page]

MA55903A - Matières et méthodes pour moduler l'immunité médiée par les lymphocytes t - Google Patents

Matières et méthodes pour moduler l'immunité médiée par les lymphocytes t

Info

Publication number
MA55903A
MA55903A MA055903A MA55903A MA55903A MA 55903 A MA55903 A MA 55903A MA 055903 A MA055903 A MA 055903A MA 55903 A MA55903 A MA 55903A MA 55903 A MA55903 A MA 55903A
Authority
MA
Morocco
Prior art keywords
lymphocyte
modulating
materials
methods
mediated immunity
Prior art date
Application number
MA055903A
Other languages
English (en)
Inventor
Rajkumar Ganesan
Iqbal S Grewal
Sanjaya Singh
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA55903A publication Critical patent/MA55903A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MA055903A 2019-05-08 2020-05-07 Matières et méthodes pour moduler l'immunité médiée par les lymphocytes t MA55903A (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962844959P 2019-05-08 2019-05-08
US201962844966P 2019-05-08 2019-05-08
US201962844976P 2019-05-08 2019-05-08
US201962844970P 2019-05-08 2019-05-08
US201962844995P 2019-05-08 2019-05-08

Publications (1)

Publication Number Publication Date
MA55903A true MA55903A (fr) 2022-03-16

Family

ID=73051172

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055903A MA55903A (fr) 2019-05-08 2020-05-07 Matières et méthodes pour moduler l'immunité médiée par les lymphocytes t

Country Status (22)

Country Link
US (2) US11667712B2 (fr)
EP (1) EP3965818A4 (fr)
JP (2) JP7686571B2 (fr)
KR (1) KR20220017892A (fr)
CN (1) CN113966231B (fr)
AU (1) AU2020267504A1 (fr)
BR (1) BR112021022089A2 (fr)
CA (1) CA3139508A1 (fr)
CL (1) CL2021002905A1 (fr)
CO (1) CO2021015998A2 (fr)
CR (1) CR20210548A (fr)
DO (1) DOP2021000229A (fr)
EC (1) ECSP21087921A (fr)
IL (1) IL287817A (fr)
JO (1) JOP20210297A1 (fr)
MA (1) MA55903A (fr)
MX (1) MX2021013532A (fr)
PE (1) PE20220763A1 (fr)
PH (1) PH12021552790A1 (fr)
SG (1) SG11202112021QA (fr)
TW (1) TW202108618A (fr)
WO (1) WO2020227457A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX386714B (es) 2015-01-27 2025-03-11 Lava Therapeutics N V Anticuerpos de dominio simple dirigidos al grupo de diferenciación 1d (cd1d).
WO2020060406A1 (fr) 2018-09-19 2020-03-26 Lava Therapeutics B.V. Nouveaux anticorps bispécifiques destinés à être utilisés dans le traitement d'hémopathies malignes
US20220306739A1 (en) * 2020-02-27 2022-09-29 Janssen Biotech, Inc. Materials and methods for modulating an immune response
US20210284731A1 (en) * 2020-03-13 2021-09-16 Janssen Biotech, Inc. Methods and materials for modulating an immune response
AR123935A1 (es) 2020-10-28 2023-01-25 Janssen Biotech Inc COMPOSICIONES Y MÉTODOS PARA MODULAR LA INMUNIDAD MEDIADA POR LA CADENA d g
BR112023017099A2 (pt) 2021-02-26 2023-11-21 Lava Therapeutics N V Anticorpos que se ligam a cd123 e a receptores de células t gama-delta
WO2025022361A1 (fr) * 2023-07-26 2025-01-30 Janssen Biotech, Inc. Matériaux et procédés de croissance cellulaire
WO2025103451A1 (fr) * 2023-11-15 2025-05-22 上海盛迪医药有限公司 Protéines de liaison à trgv9 et leur utilisation médicale

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698880B1 (fr) * 1992-11-25 1995-02-24 Inst Nat Sante Rech Med Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques.
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
AU2002351208A1 (en) 2001-12-03 2003-06-17 Abgenix, Inc. Antibodies against carbonic anhydrase IX (CA IX) tumor antigen
EP1789446A2 (fr) 2004-09-02 2007-05-30 Genentech, Inc. Molecules heteromultimeriques
TWI671403B (zh) 2005-03-31 2019-09-11 中外製藥股份有限公司 控制組裝之多肽的製造方法
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
EP1790664A1 (fr) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Anticorps monoclonaux contre claudin-18 pour le traitement du cancer
PT1999154E (pt) 2006-03-24 2013-01-24 Merck Patent Gmbh Domínios proteicos heterodiméricos modificados
EP2035456A1 (fr) 2006-06-22 2009-03-18 Novo Nordisk A/S Production d'anticorps bispécifiques
AU2008282218A1 (en) 2007-07-31 2009-02-05 Medimmune, Llc Multispecific epitope binding proteins and uses thereof
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
US20100261620A1 (en) 2008-10-14 2010-10-14 Juan Carlos Almagro Methods of Humanizing and Affinity-Maturing Antibodies
EP2424567B1 (fr) 2009-04-27 2018-11-21 OncoMed Pharmaceuticals, Inc. Procédé de fabrication de molécules hétéromultimères
EP3211094A3 (fr) 2009-09-03 2017-11-01 F. Hoffmann-La Roche AG Procédés pour traiter, diagnostiquer, et surveiller la polyarthrite rhumatoïde
FI2560993T3 (fi) 2010-04-20 2024-09-23 Genmab As Heterodimeeristä vasta-ainetta FC sisältävät proteiinit ja menetelmät niiden tuottamiseksi
CN103154026B (zh) 2010-08-05 2016-07-06 安奈普泰斯生物有限公司 抗il-17的抗体
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
UA116192C2 (uk) 2011-08-23 2018-02-26 Рош Глікарт Аг Активуюча т-клітини біоспецифічна антигензв'язуюча молекула
EP2773671B1 (fr) 2011-11-04 2021-09-15 Zymeworks Inc. Structure d'anticorps hétérodimérique stable comprenant des mutations dans le domaine fc
ES2628075T3 (es) 2011-12-19 2017-08-01 Synimmune Gmbh Molécula de anticuerpo biespecífica
US9907820B2 (en) * 2013-10-25 2018-03-06 Board Of Regents, The University Of Texas System Polyclonal gamma delta T cells for immunotherapy
JP6617138B2 (ja) 2014-04-10 2019-12-11 ラヴァ・セラピューティクス・ベー・フェー ヒトＶγ９Ｖδ２ Ｔ細胞受容体と結合する免疫グロブリン
CR20170079A (es) * 2014-09-05 2017-04-27 Janssen Pharmaceutica Nv Agentes de unión a cd123 y usos de estos
KR102660362B1 (ko) * 2014-11-17 2024-04-23 아디셋 바이오, 인크. 조작된 감마 델타 t 세포
PE20180672A1 (es) 2015-05-29 2018-04-19 Agenus Inc Anticuerpos anti-ctla-4 y metodos de uso de los mismos
EP3560955A4 (fr) 2016-12-26 2020-12-23 Kyowa Kirin Co., Ltd. Anticorps capable de se lier à la glycoprotéine d'oligodendrocytes de myéline
US11236145B2 (en) * 2017-03-23 2022-02-01 Immatics Biotechnologies Gmbh T cell receptors and immune therapy using the same against PRAME positive cancers
EP3743081A4 (fr) 2018-01-23 2021-12-01 New York University Anticorps spécifiques de la chaîne delta 1 du récepteur des lymphocytes t
US20220306739A1 (en) 2020-02-27 2022-09-29 Janssen Biotech, Inc. Materials and methods for modulating an immune response
US20210284731A1 (en) 2020-03-13 2021-09-16 Janssen Biotech, Inc. Methods and materials for modulating an immune response
AR123935A1 (es) 2020-10-28 2023-01-25 Janssen Biotech Inc COMPOSICIONES Y MÉTODOS PARA MODULAR LA INMUNIDAD MEDIADA POR LA CADENA d g

Also Published As

Publication number Publication date
JOP20210297A1 (ar) 2023-01-30
BR112021022089A2 (pt) 2022-02-08
CO2021015998A2 (es) 2021-12-10
WO2020227457A1 (fr) 2020-11-12
US11667712B2 (en) 2023-06-06
CR20210548A (es) 2022-02-11
ECSP21087921A (es) 2022-01-31
MX2021013532A (es) 2022-02-11
KR20220017892A (ko) 2022-02-14
DOP2021000229A (es) 2022-07-31
CN113966231A (zh) 2022-01-21
CL2021002905A1 (es) 2022-06-17
PE20220763A1 (es) 2022-05-16
PH12021552790A1 (en) 2022-09-05
TW202108618A (zh) 2021-03-01
CA3139508A1 (fr) 2020-11-12
JP7686571B2 (ja) 2025-06-02
AU2020267504A1 (en) 2021-12-02
CN113966231B (zh) 2025-04-01
JP2022533538A (ja) 2022-07-25
IL287817A (en) 2022-01-01
JP2024170410A (ja) 2024-12-10
SG11202112021QA (en) 2021-11-29
US20240150464A1 (en) 2024-05-09
EP3965818A1 (fr) 2022-03-16
US20210032338A1 (en) 2021-02-04
EP3965818A4 (fr) 2023-05-31

Similar Documents

Publication Publication Date Title
MA55903A (fr) Matières et méthodes pour moduler l'immunité médiée par les lymphocytes t
MA54952A (fr) Conjugués d'il-2 et méthodes d'utilisation de ceux-ci
MA50833A (fr) Compositions et méthodes pour l'édition génique pour l'hémophilie a
MA52198A (fr) Systèmes et méthodes pour l'administration retardée de médicament
EP3999079A4 (fr) Polypeptide de fusion pour l'immunothérapie
EP3786916A4 (fr) Dispositif d'aide au déplacement
EP3439675A4 (fr) Méthodes et compositions pour thérapie par lymphocytes t car
EP3534899A4 (fr) Composés et méthodes de modulation de kinase de lymphocytes t inductible par l'interleukine 2
EP3419534A4 (fr) Système d'implant pour arthroplastie de l'épaule
EP3370754A4 (fr) Méthodes pour augmenter les taux d'érythrocytes et traiter l'érythropoïèse inefficace
EP3853585C0 (fr) Méthodes de cytométrie en flux d'impédance
EP3927735A4 (fr) Combinaisons de multiples récepteurs antigéniques chimériques pour l'immunothérapie
MA54078A (fr) Méthodes pour le traitement au moyen de récepteurs antigéniques chimériques spécifiques de l'antigene de maturation des lymphocytes b
EP3402483A4 (fr) Procédés et compositions pour l'activation de lymphocytes t gamma-delta
EP3841062A4 (fr) Dispositifs et méthodes pour membranes de filtration d'eau
EP3920926A4 (fr) Procédés et compositions pour moduler l'épissage
MA51645A (fr) Modulateurs de l'expression de dnm2
EP3880710A4 (fr) Anticorps anti-cd73 activant les lymphocytes b
MA53924A (fr) Modulateurs de l'expression d'apol1
EP3852925C0 (fr) Appareil de cytométrie de flux d'impédance
EP3860890C0 (fr) Essieu monté et système d'entraînement pour un véhicule ferroviaire
EP3526408A4 (fr) Escalier d'accès pour véhicule de transfert de matériau
EP4171587A4 (fr) Récepteurs de lymphocytes t spécifiques d'antigènes et récepteurs antigéniques chimériques, et méthodes d'utilisation dans la modulation de la signalisation immunitaire pour l'immunothérapie anticancéreuse
EP3784777A4 (fr) Récepteurs antigéniques chimériques et édition génique de cd2 pour l'immunothérapie des malignités des lymphocytes t
EP4022523A4 (fr) Fonctions d'activation pour des opérations d'intelligence artificielle