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MA47678A - Plateforme personnalisée d'identification de peptide immunogène - Google Patents

Plateforme personnalisée d'identification de peptide immunogène

Info

Publication number
MA47678A
MA47678A MA047678A MA47678A MA47678A MA 47678 A MA47678 A MA 47678A MA 047678 A MA047678 A MA 047678A MA 47678 A MA47678 A MA 47678A MA 47678 A MA47678 A MA 47678A
Authority
MA
Morocco
Prior art keywords
immunogenic peptide
identification platform
peptide identification
personalized
personalized immunogenic
Prior art date
Application number
MA047678A
Other languages
English (en)
Inventor
Zsolt Csiszovszki
Julianna Lisziewicz
Orsolya Lorincz
Mónika Megyesi
Levente Molnár
Katalin Pántya
Eszter Somogyi
József Toth
Enikö R Töke
Original Assignee
Treos Bio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61386864&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA47678(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from EP17159243.9A external-priority patent/EP3370065A1/fr
Priority claimed from EP17159242.1A external-priority patent/EP3369431A1/fr
Priority claimed from GBGB1703809.2A external-priority patent/GB201703809D0/en
Application filed by Treos Bio Ltd filed Critical Treos Bio Ltd
Publication of MA47678A publication Critical patent/MA47678A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
MA047678A 2017-03-03 2018-03-02 Plateforme personnalisée d'identification de peptide immunogène MA47678A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17159243.9A EP3370065A1 (fr) 2017-03-03 2017-03-03 Peptides immunogènes
EP17159242.1A EP3369431A1 (fr) 2017-03-03 2017-03-03 Vaccin
GBGB1703809.2A GB201703809D0 (en) 2017-03-09 2017-03-09 Vaccine

Publications (1)

Publication Number Publication Date
MA47678A true MA47678A (fr) 2021-05-26

Family

ID=61386864

Family Applications (3)

Application Number Title Priority Date Filing Date
MA047683A MA47683A (fr) 2017-03-03 2018-03-02 Plate-forme d'identification de peptide immunogène reposant sur une population
MA047678A MA47678A (fr) 2017-03-03 2018-03-02 Plateforme personnalisée d'identification de peptide immunogène
MA047677A MA47677A (fr) 2017-03-03 2018-03-02 Vaccins peptidiques

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA047683A MA47683A (fr) 2017-03-03 2018-03-02 Plate-forme d'identification de peptide immunogène reposant sur une population

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Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016235388B2 (en) * 2015-03-20 2022-02-03 Children's National Medical Center Generating virus or other antigen-specific T cells from a naive T cell population
CA3054866A1 (fr) 2017-03-03 2018-09-07 Treos Bio Zrt Plateforme personnalisee d'identification de peptide immunogene
GB201814361D0 (en) * 2018-09-04 2018-10-17 Treos Bio Zrt Immunogenetic cancer screening test
JP7642530B2 (ja) 2018-09-04 2025-03-10 トレオス バイオ リミテッド ペプチドワクチン
GB201814362D0 (en) 2018-09-04 2018-10-17 Treos Bio Zrt Composition and process for preparing vaccine
TW202028224A (zh) * 2018-09-17 2020-08-01 德商英麥提克生物技術股份有限公司 B*44限制肽在抗癌免疫治療的用途和相關方法
TW202039535A (zh) * 2018-12-18 2020-11-01 德商英麥提克生物技術股份有限公司 B*08限制肽和肽組合物抗癌免疫治療和相關方法
KR102159921B1 (ko) * 2020-03-24 2020-09-25 주식회사 테라젠바이오 펩타이드 서열 및 hla 대립유전자 서열을 이용하여 신생항원을 예측하는 방법 및 컴퓨터 프로그램
GB202004974D0 (en) 2020-04-03 2020-05-20 Treos Bio Ltd Coronavirus vaccine
CN115715199A (zh) 2020-04-03 2023-02-24 帕普泰克疫苗有限公司 冠状病毒疫苗
US20230024150A1 (en) * 2020-04-20 2023-01-26 NEC Laboratories Europe GmbH Method and system for optimal vaccine design
CN112048001B (zh) * 2020-09-08 2022-04-05 南方科技大学 一种肿瘤新生抗原多肽及其应用
KR102278727B1 (ko) * 2020-09-16 2021-07-19 주식회사 테라젠바이오 대상 암 조직 및 세포 유리형 dna 유래 펩타이드 서열 및 hla 클래스 ii 대립유전자 서열을 이용하여 신생항원을 예측하는 방법 및 컴퓨터 프로그램
JP7627826B2 (ja) 2021-08-10 2025-02-07 日本電気株式会社 情報処理システム及び情報処理方法
TW202322137A (zh) 2021-10-04 2023-06-01 日商日本電氣股份有限公司 管理方法、管理系統及電子健康紀錄系統
US20240424094A1 (en) * 2021-10-06 2024-12-26 CancerVAX Inc. Methods and compositions for cancer treatment
EP4516932A1 (fr) * 2022-04-27 2025-03-05 POSTECH Research and Business Development Foundation Procédé de construction de molécules hybrides peptide-acide nucléique issues de points chauds reposant sur une sélection in vitro
CN115785203B (zh) * 2022-06-10 2024-03-12 河北博海生物工程开发有限公司 肺癌特异性分子靶标10及其用途
WO2024038510A1 (fr) 2022-08-17 2024-02-22 日本電気株式会社 Système de traitement d'informations, procédé de traitement d'informations et programme
GB202216453D0 (en) 2022-11-04 2022-12-21 Lisziewicz Julianna Identification of antigens which induce t-cell responses

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235877A (en) 1979-06-27 1980-11-25 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
CA2248657A1 (fr) 1996-03-11 1997-09-18 Epimmune Inc. Peptides presentant une affinite accrue de liaison avec des molecules
US6617434B1 (en) 1996-05-31 2003-09-09 North Shore Long Island Jewish Research Institute Identificiaton of differentially methylated and mutated nucleic acids
US20030148463A1 (en) 1997-04-14 2003-08-07 Micromet Ag Novel method for the production of anti-human antigen receptors and uses thereof
ATE200679T1 (de) * 1997-04-14 2001-05-15 Micromet Ag Neues verfahren zur herstellung von anti-humanen antigenrezeptoren und deren verwendungen
FR2791895B1 (fr) 1999-03-23 2001-06-15 Pasteur Merieux Serums Vacc Utilisation de trehalose pour stabiliser un vaccin liquide
AUPQ776100A0 (en) 2000-05-26 2000-06-15 Australian National University, The Synthetic molecules and uses therefor
US6673580B2 (en) 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
US7892559B2 (en) 2002-01-30 2011-02-22 Survac Aps Survivin-derived peptides and use thereof
CN1691964A (zh) 2002-09-06 2005-11-02 曼康公司 表位序列
GB0228900D0 (en) * 2002-12-11 2003-01-15 Ml Lab Plc Cancer Immunotherapy
US20060257852A1 (en) 2003-04-10 2006-11-16 Chiron Corporation Severe acute respiratory syndrome coronavirus
US20050100883A1 (en) 2003-11-12 2005-05-12 Wang Chang Y. Peptide-based diagnostic reagents for SARS
JP4779067B2 (ja) * 2004-01-20 2011-09-21 愛知県 ＨＬＡ−Ａ２４０２拘束性Ｅｐ−ＣＡＭ特異的ＣＴＬが認識するエピトープ・ペプチド及びその用途
EP1756147A2 (fr) 2004-06-01 2007-02-28 Innogenetics N.V. Peptides pour provoquer une réponse ctl et/ou htl à un antigène de l'hépatite c
JP4475469B2 (ja) 2005-01-25 2010-06-09 日本電気株式会社 Ｈｌａ結合性ペプチド、それをコードするｄｎａ断片および組み換えベクター
CA2593714C (fr) 2005-02-04 2013-09-10 Survac Aps Vaccin a base de peptide de survivine
CN100402554C (zh) * 2005-02-25 2008-07-16 李玉新 睾丸特异性蛋白50人源抗体的制备及用途
FR2891462B1 (fr) 2005-09-30 2009-10-16 Commissariat Energie Atomique Epitopes t cd4+ de la survivine et leurs applications
GB0520067D0 (en) 2005-10-01 2005-11-09 Cancer Rec Tech Ltd Treatment of cancer
AU2007298494B2 (en) 2006-09-21 2013-09-26 Vaxil Biotherapeutics Ltd. Antigen specific multi epitope vaccines
CA2700573C (fr) 2006-09-26 2016-11-22 Cedars-Sinai Medical Center Vaccins comprenant des antigenes de cellules souches cancereuses et procedes
EP2155782A2 (fr) 2007-03-26 2010-02-24 Dako Denmark A/S Complexes peptidiques du cmh et leurs utilisations dans des maladies infectieuses
EP2042600A1 (fr) * 2007-09-28 2009-04-01 Commissariat A L'energie Atomique Epitope de cellule CD4+ T publique et immunogène de la protéine tat vih et ses applications
CN105330733A (zh) 2008-03-31 2016-02-17 株式会社生物免疫平衡 MHC II类分子提呈的存活蛋白（Survivin）的部分肽及其利用方法
DK2119726T5 (en) 2008-05-14 2018-03-26 Immatics Biotechnologies Gmbh Novel and powerful MHC class II peptides derived from survivin and neurocan
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
EP2337795A2 (fr) 2008-10-01 2011-06-29 Dako Denmark A/S Multimères de mhc dans des vaccins et la surveillance immunitaire contre le cancer
GB0818065D0 (en) * 2008-10-02 2008-11-05 Cancer Rec Tech Ltd Immunogenic peptides and uses thereof
US20120244145A1 (en) * 2009-11-16 2012-09-27 Duke University Enhanced immunological responses
GB201004575D0 (en) * 2010-03-19 2010-05-05 Immatics Biotechnologies Gmbh Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers
US20170039314A1 (en) * 2010-03-23 2017-02-09 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
WO2012051282A2 (fr) * 2010-10-14 2012-04-19 The Ohio State University Research Foundation Diagnostic et thérapie du cancer ciblés sur des protéines de type piwil2 (pl2l)
EP2745845A1 (fr) * 2012-12-19 2014-06-25 Centre Hospitalier Universitaire de Bordeaux Procédé de prévention ou de traitement d'une infection par VIH
WO2014180490A1 (fr) * 2013-05-10 2014-11-13 Biontech Ag Prédiction de l'immunogénicité d'épitopes de lymphocytes t
GB201315946D0 (en) 2013-09-06 2013-10-23 Immune Targeting Systems Its Ltd Oncology vaccine
WO2015069770A1 (fr) * 2013-11-05 2015-05-14 Cognate Bioservices, Inc. Combinaisons d'inhibiteurs de point de contrôle et d'agents thérapeutiques pour traiter un cancer
WO2015143335A1 (fr) 2014-03-20 2015-09-24 The University Of North Carolina At Chapel Hill Méthodes et compositions pour protéines spike de coronavirus chimère
US10111948B2 (en) 2014-04-25 2018-10-30 Tria Bioscience Corp. Synthetic hapten carrier compositions and methods
WO2016040900A1 (fr) * 2014-09-14 2016-03-17 Washington University Vaccins anticancéreux personnalisés, et procédés correspondants
CA2969231C (fr) * 2014-12-03 2021-06-08 Verik Bio, Inc. Identification, selection et utilisation d'epitopes de cellule t a haut potentiel curatif
EP3286361A4 (fr) * 2015-04-23 2019-05-08 Nantomics, LLC Néo-épitopes de cancer
US11090332B2 (en) 2015-05-21 2021-08-17 Regen BioPharma, Inc. Antigen specific mRNA cellular cancer vaccines
JP2018532736A (ja) * 2015-10-12 2018-11-08 ナントミクス，エルエルシー チェックポイント阻害物質への感受性を予測するｍｓｉおよびネオエピトープの探索のための系、組成物、および方法
GB201604755D0 (en) 2016-03-21 2016-05-04 Vaxeal Res Sas Immunogenic compositions
JP2020503840A (ja) 2016-10-07 2020-02-06 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Ｈｌａ拘束性ｖｇｌｌ１ペプチドおよびその使用
TWI796314B (zh) 2017-01-27 2023-03-21 德商英麥提克生物技術股份有限公司 用於卵巢癌和其他癌症免疫治療的新型肽和肽組合物
CA3054866A1 (fr) 2017-03-03 2018-09-07 Treos Bio Zrt Plateforme personnalisee d'identification de peptide immunogene
EP3369431A1 (fr) 2017-03-03 2018-09-05 Treos Bio Kft Vaccin
EP3370065A1 (fr) 2017-03-03 2018-09-05 Treos Bio Kft Peptides immunogènes
WO2019133853A1 (fr) 2017-12-28 2019-07-04 Gritstone Oncology, Inc. Protéines se liant à l'antigène ciblant des antigènes partagés
WO2019222762A1 (fr) 2018-05-18 2019-11-21 Children's National Medical Center Compositions de thérapie cellulaire améliorées pour patients ayant subi une transplantation de cellules souches hématopoïétiques
CA3100775A1 (fr) 2018-05-18 2019-11-21 Children's National Medical Center Therapie ciblee amelioree par lymphocytes t
JP7642530B2 (ja) 2018-09-04 2025-03-10 トレオス バイオ リミテッド ペプチドワクチン
GB201814362D0 (en) 2018-09-04 2018-10-17 Treos Bio Zrt Composition and process for preparing vaccine
GB201814361D0 (en) 2018-09-04 2018-10-17 Treos Bio Zrt Immunogenetic cancer screening test
EP3908292A4 (fr) 2019-01-07 2023-01-04 Children's National Medical Center Thérapie améliorée à lymphocytes t ciblés pour le traitement du myélome multiple
US20220064598A1 (en) 2019-01-07 2022-03-03 Children's National Medical Center Ex vivo activated t-lymphocytic compositions and methods of using the same
GB202004974D0 (en) 2020-04-03 2020-05-20 Treos Bio Ltd Coronavirus vaccine

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